Oligosaccharides

<p>Applications 1-O-n-Octyl-d17-beta-D-glucopyranoside (CAS# 129522-81-2) is a useful isotopically labeled research compound.<br></p>

<p>Stability Moisture Sensitive<br>Applications US Pat. 7033765<br></p>

<p>Applications Propylene Glycol 1-Glucuronide is a metabolite of propylene glycol, used in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds.<br>References Szczepankiewicz, B. et al.: J. Med. Chem., 49, 3563 (2006); Mateus, R. et al.: Int. J. Pharm., 444, 106 (2013);<br></p>

<p>Applications 5'-(Methyl-d3-thio)adenosine (CAS# 174838-38-1) is a useful isotopically labeled research compound, where it is used in synthesis reactions.<br>References Sugiyama, T., et.al., Nucleic Acids Symp.Ser., 34,13-14,(1995);<br></p>

<p>Stability Hygroscopic<br>Applications 6-Deoxy-D-talose is an derivative of D-Talose (T005560), a monosaccharide sugar that can convert between aldose and ketose forms in pyridine in the presence of aluminum oxide.<br>References Davies, S.G., et al.: Org. Biomolec. Chem., 3, 348 (2005);<br></p>

<p>Applications Cytidine-5,6-d2 (CAS# 40632-25-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Cytarabine-5,6-d2 (CAS# 40632-26-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications An iridoid glycoside that exhibits protective effects against hepatic injury and other diabetic complications associated with abnormal metabolic states and inflammation caused by oxidative stress and advanced glycation endproduct formation. A potential anti-amnesic agent.<br>References Yamabe, N. et al.: Eur. J. Pharmmacol., 648, 179 (2010); de Carman Recio, M. et al.: Planta Medica, 3, 232 (1994); Kwon, S. et al.: Eur. J. Pharmacol., 619, 44 (2009);<br></p>

<p>Applications Methyl 4-Deoxy-4-fluoro-α-D-glucose (cas# 56926-53-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Polyhyllin VI is a natural saponin extracted from the plant, Rhizoma Paridis, and displays anti-proliferative activity in vivo. Used in the treatment of HepG2 cells for tumor mitigation.<br>References Ma, D. et al.: J. Int Med. Res., 37, 631 (2009); Yin, X. et al.: Biomed. Chrom., 27, 343 (2013); Jiang, H. et al.: Mol. Med. Rep., 9, 2265 (2014); Cheng, Z. et al.: J. Ethnopharmacol., 120, 129 (2008);<br></p>

<p>Applications 4-O-β-D-Mannopyranosyl-D-glucopyranoside (cas# 29276-55-9) is a compound useful in organic synthesis.<br></p>

<p>Gala1-3Galb1-3GlcNac</p>

<p>A mixture of sodium trigalacturonate &amp; tetragalacturonate (α-1,4 sodium galacturonotriose + α-1,4 sodium galacturonotetraose) is derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s), and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides, restore development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>b1-4-Galactosyl-Galactose-BSA is a carbohydrate, modification and saccharide that is an Oligosaccharide and sugar. It is custom synthesized and has high purity. This compound can be fluorinated, complexed, or methylated. It also contains glycosylation or click modification.</p>

<p>Methyl b-N-acetyllactosamine is a sulfated glycosaminoglycan (GAG) that is expressed in the brain and is involved in the development of myelin. This compound has been shown to inhibit the transfer of sulfate groups, which are essential for the synthesis of GAGs. Methyl b-N-acetyllactosamine inhibits transglycosylation reactions, which is a process by which sugar moieties are transferred from one molecule to another. This inhibition results in decreased cross-coupling reactions and decreases the production of GAGs. Methyl b-N-acetyllactosamine has been shown to have potent inhibitory properties against sulfonylating enzymes, such as regiospecifically catalyzed sulfonylation and transglycosylation. It also has been shown to inhibit the transition state in an enzymatic reaction involving triazoles.</p>

Globo-N-tetraose conjugated to HSA with acetyl-phenylenediamine spacer

<p>1,5-a-L-Arabinoheptaose is a sugar that is found in the cell walls of bacteria. The chemical modification of this sugar has been studied extensively. The modification of this sugar with methyl groups and click chemistry has been shown to alter its properties, such as binding affinity and solubility. This modified sugar can be used for glycosylation reactions or custom synthesis. 1,5-a-L-Arabinoheptaose is also available in high purity and with a custom synthesis.</p>