Oligosaccharides

<p>ABO trisaccharide immobilised on Fractogel with glycosylamine formation</p>

<p>Globo series antigen</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>Computational fluid dynamics (CFD) is the study of fluid flow, a subject which has been studied for over two thousand years. The idea of CFD is to use computers to solve the equations that govern fluid flow and to make predictions about the behavior of gases, liquids and complex fluids in various situations. Computational analysis can be used to calculate how air flows around an object such as a car or plane. This allows engineers to create designs with less drag. Computational analysis can also be used in designing buildings, bridges, and other structures that are exposed to large amounts of wind. <br>CFD is a "convective" computational method because it solves problems by using convection-diffusion equations with appropriate boundary conditions. A "transport" computational method solves problems by solving momentum equations and energy conservation equations simultaneously; this method is often more accurate than convective methods but computationally more expensive. A "laminar" computational method solves problems by solving continuity equations. A "nature</p>

<p>Hyaluronate fluorescein is a polymer of hyaluronic acid that has been modified with fluorescein. It is synthesized by the methylation and saccharide coupling of an oligosaccharide, followed by Click modification and the addition of a fluorescent dye. Hyaluronate fluorescein has a molecular weight of 2500kDa. It is highly purified and can be custom-synthesized to suit specific needs.</p>

<p>This product is a fatty acid that binds to the carbohydrate binding sites in the cell membrane of Caco-2 cells. It has been shown to inhibit the growth of cancer cells and radiation induced changes by binding to the sugar moieties on glycoproteins. This product also inhibits the production of glycoconjugates, which are important for cell-cell interactions and biological function. The disaccharide form has been found to be a diagnostic agent for cancer cells, with a structural formula that can be seen in the figure below.</p>

<p>Sulpho Lewisa Na is a complex carbohydrate that has been modified with fluorination and methylation. This product is custom synthesized, high purity, and has a CAS number. It is available for synthesis in various lengths of saccharides with a variety of modifications. Sulpho Lewisa Na can be used in the following applications: glycosylations, click modification, and methylation.</p>

Difucosyl-para-lacto-N-hexaose-APD-HSA is a complex carbohydrate that is a custom synthesis. It has been modified by the addition of difucosyl groups to the para position of lactose and by the attachment of an APD moiety to the N-acetyl group of hexitol. The molecular weight is approximately 1,000 Da. This product is used in glycosylation reactions, such as polysaccharide synthesis, and in fluorination reactions. Difucosyl-para-lacto-N-hexaose-APD-HSA can be found under CAS No. 366511-00-7 and is soluble in water and DMSO.

<p>The Lewis X trisaccharide 4-methylumbelliferyl glycoside is a high purity, custom synthesis sugar that has been fluorinated and glycosylated. This product is a complex carbohydrate that can be used for various purposes. The CAS number for this product is 359436-57-0.</p>

<p>Difucosyl-para-lacto-N-neohexaose is an extracellular, acidic oligosaccharide with a lactose backbone and two fucoses attached to the 2' position. Difucosyl-para-lacto-N-neohexaose is found in human milk and has been shown to be a potent inhibitor of the lectin anagyroides. Difucosyl-para-lacto-N-neohexaose is composed of tetraoses linked by α(1→4) glycosidic bonds. The linkage between the first two sugars of each tetraose can be either α(1→6) or β(1→3). The linkage between the second two sugars in each tetraose can be either β(1→4) or α(1→6). This linkage pattern restricts the possible structures to six different types,</p>

Hyaluronate rhodamine is a synthetic, high-purity, fluorinated, hydrophilic oligosaccharide. It is a complex carbohydrate with a molecular weight of 1500kDa and a very low viscosity. Hyaluronate rhodamine has been modified to include Click chemistry that provides the potential for site-specific modification on the sugar backbone. The fluorination process can be customized to produce the desired degree of substitution (DS) and functionalization for specific applications. This product has been glycosylated and polysaccharide modified to create an oligosaccharide that is suitable for use in therapeutic and diagnostic applications.

2, 3, 6, 2', 3', 4', 6'-Hepta-O-acetyl-D-maltose is a fluorinated monosaccharide that is used in the synthesis of glycosides. It has a CAS number of 56285-96-2 and can be custom synthesized. This product is an oligosaccharide that can be modified by glycosylation, methylation, or click modification. It is a complex carbohydrate with a high purity and can be used in the modification of sugars.

<p>GalNAca1-3Galb1-4GlcNAc</p>

<p>Heparin derived dp24 saccharide ammonium salt is a complex carbohydrate and a saccharide. It is used for the modification of polysaccharides and oligosaccharides. The compound has been shown to reduce blood coagulation by preventing the binding of calcium ions to thrombin, which then blocks the conversion of fibrinogen to fibrin. Heparin derived dp24 saccharide ammonium salt has high purity and can be custom synthesized with high quality. The compound is also methylated, glycosylated, or click-modified.</p>

<p>GM3-ganglioside NBD (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue with nitrobenzoxadiazole (NBD) linked β to position 1 on the reducing terminal glucose residue, in place of the ceramide fatty acid (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain, and melanomas, where it is frequently found to be overexpressed. GM3 ganglioside is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function, and immune disorders (e.g. allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and is a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>APF Sialoglycopeptide ammonium salt is a custom synthesis of sialoglycopeptides. The molecule is modified with fluorination, methylation and click modification. It contains a monosaccharide and an oligosaccharide. The saccharide is glycosylated to a complex carbohydrate. APF Sialoglycopeptide ammonium salt has CAS No.:</p>

<p>Benzyl 2-acetamido-3-O-(2,3,4-tri-O-benzyl-a-L-fucopyranosyl)-4,6-O-benzylidene-2-deoxy-a-D-glucopyranoside is a high purity custom synthesis sugar. This compound has been synthesized by Click modification of the amino acid glycoside and fluorination of the sugar. It is an Oligosaccharide with a saccharide chain composed of Monosaccharides and Carbohydrates. The CAS number for this compound is 196941 – 73 – 8.</p>

<p>Useful for raising antibodies to Blood Group B</p>

4-Methoxyphenyl 4-O-(2,4,6-tri-O-benzyl-b-D-galactopyranosyl)-2,3,6-tri-O-benzyl-b-D-glucopyranoside is a suppressor of genes that has been shown to be active in the treatment of leukemia. It suppresses transcription by inhibiting histone H3 acetylation and DNA replication by binding to the dna replication complex at sites of replication. The suppression of genes may be due to its ability to inhibit translation by blocking signal sequences and hybridization with complementary mRNA.

<p>The maltose solution we offer is a 20% solution in water and of high purity and can be customized to meet your needs.</p>