Oligosaccharides

<p>GD1b ganglioside (shown as ammonium salt) is one of the major gangliosides in neuronal and glial membranes. It has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with its two sialic acids linked α2,3/α2,8 to the inner galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD1b ganglioside acts as a receptor for BK virus, as well as for heat-labile LTII-a toxin, produced by enteropathogenic E. coli. GD1b ganglioside also interacts with tetanus neurotoxin (TeNT) and is crucial for its entry into cells (Kolter, 2012). The functional significance of ammonia in the brain is not yet fully understood: see (Modi 1994).</p>

<p>Hyaluronate fluorescein is a fluorinated carbohydrate that has been modified for use in the detection of methylation. It contains an oligosaccharide and polysaccharide that are attached to a 20kDa fluorinated saccharide. This product is available in high purity and is custom synthesized for your specific needs.</p>

<p>Tool for studying carbohydrate metabolism</p>

<p>Tumor associated antigen and target for the development of anti-cancer vaccines.</p>

<p>The 6-O-[2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-b-D-glucopyranosyl]-D-galactopyranose is a disaccharide carbohydrate that can be found in the blood group H. This particular carbohydrate is an example of a sialic acid, which plays an important role in the immune system and other biological processes. Lectins are proteins that bind to carbohydrates and are often used as probes to study glycan structures. Lectin binding assays have been used to characterize this molecule as well as oligosaccharides, glycans, and biohazards.</p>

<p>Useful glycosylation donor</p>

<p>Methyl 4-O-[4,6-O-benzylidene)-b-D-galactopyranosyl] b-D-glucopyranoside is a synthetic sugar with a high purity and custom synthesis. It has been modified by fluorination, methylation, glycosylation, and click modification. This product can be used as a pharmaceutical ingredient for the treatment of tuberculosis.</p>

<p>Decyl 4-O-b-D-lactopyranosyl-b-D-lactopyranoside is a high purity, custom synthesis, glycosylated oligosaccharide. It has been modified with Click chemistry to incorporate a fluorine atom on the sugar ring. This complex carbohydrate has a CAS No. of 1858224-00-6 and is synthesized by methylation and fluorination reactions. Decyl 4-O-b-D-lactopyranosyl-b-D-lactopyranoside can be used in biomedical research as a model for glycans and glycolipids, as well as in industrial applications such as food production.</p>

<p>3,4,2',3',6'-Penta-O-acetylsucrose is a deuterated analog of sucrose. It can be synthesized by reacting sucrose with acetyl chloride in the presence of a base. The transesterification reaction yields the desired product in an overall yield of about 20%. This process is similar to that used for the synthesis of fatty acid esters, but 3,4,2',3',6'-Penta-O-acetylsucrose does not exist in nature and cannot be found as a natural product. The X-ray crystallography studies show that 3,4,2',3',6'-Penta-O-acetylsucrose has a conformation different from that of 6-phosphate sucrose.</p>

<p>Blood group antigen derivative with spacer arm</p>

<p>Linear B-6 trisaccharide 1-O-n-pentylamine is a glycosylated, fluorinated, saccharide that can be custom synthesized. This compound can be modified with methyl groups, click chemistry, or fluorination. It has a CAS number of 188768-84-0 and is soluble in methanol, ethanol, and water. Linear B-6 trisaccharide 1-O-n-pentylamine is a monosaccharide with a molecular weight of 258.</p>

<p>Galb1-3Galb1-4GlcNAcb1-3Galb1-4Glc is a complex carbohydrate that is synthesized from Galb1-4GlcNAcb1-3Galb1-4Glc and 3,6-anhydro-L-galactose. It has been modified with fluorination to prevent degradation. The synthesis of this product may be modified by methylation, glycosylation, or carbonylation. Galb1-3Galb1-4GlcNAcb1-3Galb1-4Glc has CAS No. 443660-52-4 and a purity of 96%. This product is stable at room temperature and may be used in the preparation of vaccines or diagnostic kits.</p>

<p>2-Acetamido-2-deoxy-6-a-O-sialyl-D-galactopyranose is a monosaccharide that is synthesized from D-galactose and acetamide. It has a molecular weight of 388.13 and an empirical formula of C8H14N2O4. This product can be custom synthesized to meet the needs of customers, with a purity level of 98%. 2-Acetamido-2-deoxy-6-a-O-sialyl--D--galactopyranose is used in glycosylation reactions, as well as in the synthesis of oligosaccharides, sugar and saccharide derivatives. This product can also be used for fluorination reactions, methylation reactions, and click modification reactions.</p>

<p>Allyl β-D-lactose is a disaccharide with an aliphatic alkene functional handle.  This can be used as a functionalised monomer in the synthesis of glycopolymers.</p>

<p>Hyaluronate biotin (HB) is a modified form of hyaluronic acid. It is produced by the methylation and glycosylation of hyaluronic acid and it has an average molecular weight of 250 kDa. HB is used in tissue engineering, cell culture, and as a contrast agent for magnetic resonance imaging. The modification of hyaluronate with biotin allows for the visualization of HB using immunofluorescence microscopy. Hyaluronate biotin is a synthetic product that can be custom-synthesized to customer specifications, such as purity level, oligosaccharide content, and monosaccharide content.</p>

<p>Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions.</p>

<p>Lactosyl-b-1,1'-N-octanoyl-L-threo-sphingosine is a glycosylation agent that is used in the synthesis of complex carbohydrates. This compound has been shown to be stable in aqueous solutions and can be used for the modification of saccharides, oligosaccharides, and polysaccharides. Lactosyl-b-1,1'-N-octanoyl-L-threo-sphingosine is also useful for the fluorination of sugars. The CAS number for this compound is 939036-94-9.</p>

<p>GT2 oligosaccharide (free acid) has a core trisaccharide structure (GalNAcβ1,4Galβ1,4Glc) with three sialic acid residues (NeuAc) linked α2,8/α2,8/α2,3 to the inner galactose residue (Ledeen, 2009). GT2 oligosaccharide is the carbohydrate moiety in the GT2 ganglioside. A key role has been reported for gangliosides, such as, GT1b and GT2 as modulators in the interaction between microglia (resident cells of the brain that regulate brain development) and brain tumors. It is possible that they will be important targets for therapeutical intervention in the near future (Daniele, 2020). In addition, C-series gangliosides, such as GT3, GT2, GQ1c, and CP1c are expressed in normal pancreatic tissue but are practically lost in the pancreas of diabetic animals (Saito, 1999).</p>

<p>1,3:1,4-B-glucotetraose (A) is a high purity and custom synthesis of Oligosaccharide. It is an oligosaccharide sugar derived from glucose. The chemical structure contains an alpha-(1,4)-linked 1,4-alpha-D-glucopyranosyl residue with a glycosylation at the 3 position. 1,3:1,4-B-glucotetraose (A) is synthesized by methylation of 1,3:1,4-B-glucotetraose (B), followed by fluorination and then click modification. This compound has CAS No. 58484-04-1 and can be used in applications such as Fluorination or Click Modification.</p>

<p>Difucosyl-para-lacto-N-hexaose III is a custom synthesis. It is an oligosaccharide that belongs to the class of polysaccharides. It has a molecular weight of 1,000 Da and contains two monosaccharides: difucose and para-lactohexose. This product can be modified with fluorination or click chemistry. Difucosyl-para-lacto-N-hexaose III has a purity of &gt; 98% and CAS No., which is 93794-37-5.</p>