Oligosaccharides

<p>1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] is a complex carbohydrate that contains a fluorinated sugar. It is synthesized from a monosaccharide and an oligosaccharide and glycosylated with a polysaccharide. The compound has been modified to include methylation and click modification. 1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] can be purchased in high purity from the CAS registry number of 538570–75–6.</p>

<p>Gal[2346Ac]b(1-3)GlcN3[46Bzd]-b-MP is a custom synthesis that has been modified with fluorination, methylation, and modification. The product contains a monosaccharide, oligosaccharide, saccharides, and complex carbohydrates.</p>

<p>Tool for studying carbohydrate metabolism</p>

<p>Binder in tablets; food additive; has several pharmaceutical applications</p>

<p>GM1a pentasaccharide (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the inner galactose residue (Ledeen, 2009). GM1a pentasaccharide is the carbohydrate moiety in GM1a ganglioside which interacts and modulates tyrosine kinases, such as, neural tropomyosin receptor kinase A (TrkA), by inducing the release of neurotrophins from fibroblast cells and the epidermal growth factor receptor (EGFR) (Higuero, 2009). Oligosaccharide domain of monosialylated glycosphingolipid GM1 of a-series that specifically interacts with cholera toxin B subunit (CBT) from V. cholerae, heat-labile toxin B subunit (LTB) from E. coli and alpha toxin from C. perfrigens. This ganglioside is abundant in nervous system as well as in other peripheral tissues (Chiricozzi, 2020).</p>

<p>Chondroitin is a complex carbohydrate that consists of repeating disaccharides of glucuronic acid and N-acetylgalactosamine. Chondroitin di-diSE trisodium salt is a synthetic chondroitin with the same chemical structure as natural chondroitin, but it has been modified to increase its solubility in water. This product is available as a white powder in bulk or as a custom synthesis, which is available in any desired quantity. It has high purity, methylation, glycosylation, and click modification.</p>

<p>NGA2 Glycan, 2-AB labelled is a complex carbohydrate that is custom synthesized for research purposes. It is a high purity, high quality product that has been fluorinated and glycosylated. NGA2 Glycan, 2-AB labelled is used in the synthesis of oligosaccharides and polysaccharides. This product can be used for glycosylation, methylation and click modification.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-b-D-lactosyl isothiocyanate is a fluorinated oligosaccharide that has been custom synthesized with a click modification. This compound is a high purity product and can be used in the synthesis of complex carbohydrates.</p>

<p>A3 N-Glycan is a glycosylation profile marker that is specific for the cancer cells. It discriminates between healthy and cancerous cells, which has been shown by analyzing the A3 N-glycan profiles in human plasma samples. The A3 N-glycan marker is detected using high performance liquid chromatography (HPL) analysis. This assay can be used to diagnose cancer and monitor its progression.</p>

<p>Gala1-3(Fuca1-2)Galb1-3GlcNAc</p>

<p>Lacto-N-difucohexaose I-APD-HSA is a custom synthesis of an oligosaccharide with a molecular weight of 5,000 Da. It is modified with fluorine and methyl groups at the C6 and C1 positions. Lacto-N-difucohexaose I-APD-HSA is synthesized by click chemistry and has been shown to be effective in inhibiting the growth of cancer cells. This sugar can be modified by glycosylation or carbohydrate modification.</p>

<p>A disaccharide</p>

<p>D-Fructose-13C6-1,6-diphosphate sodium salt is a reactive compound used as a model in studies of metabolic disorders. It has been shown to have an inhibitory effect on the enzymes that catalyze the conversion of D-fructose 1,6 diphosphate to D-fructose 6 phosphate in the cytosol. The compound is also useful for determining the binding of calcium ions to proteins and for measuring the activity of carbon source enzymes.</p>

<p>This is a custom synthesis for a polysaccharide. The CAS number is not available. It is a complex carbohydrate that contains an oligosaccharide. This polysaccharide has been modified with methylation and glycosylation, as well as click modification. It can be fluorinated to increase the purity. It is a sugar with high purity.</p>

<p>Galacto-N-biose-PAA-biotin is a carbohydrate that is synthesized by the addition of PAA (polyallylamine) to galactose. This compound can be used in fluorescence labeling and detection of carbohydrates, glycosylation, and polysaccharide synthesis. Galacto-N-biose-PAA-biotin has a CAS number (CAS: 146988-01-4).</p>

<p>ABO trisaccharide immobilised on Fractogel with glycosylamine formation</p>

<p>Disaccharide alcohol from agarobiose by reduction with Na borohydride</p>

<p>Used for treatment of duodenal ulcers and gastroesophageal reflux</p>

<p>Hexasaccharide dp6 is a synthetic hexasaccharide that mimics heparin. It binds to the antithrombin III and pentasaccharide in human plasma, which are proteins that inhibit blood clotting. Hexasaccharide dp6 also has affinity for peptides from HIV-1 and anti-HIV activity. Hexasaccharide dp6 can be used to prevent coagulation or as an antithrombotic agent.</p>

<p>This product is a fatty acid that binds to the carbohydrate binding sites in the cell membrane of Caco-2 cells. It has been shown to inhibit the growth of cancer cells and radiation induced changes by binding to the sugar moieties on glycoproteins. This product also inhibits the production of glycoconjugates, which are important for cell-cell interactions and biological function. The disaccharide form has been found to be a diagnostic agent for cancer cells, with a structural formula that can be seen in the figure below.</p>