Polycyclic Compounds

Stability Hygroscopic
Applications 5-Amino-6-nitroquinoline is a reagent used in the synthesis of benzodiazepine sulfonamide-based bombesin receptor 3 agonists. It is also used in the synthesis of quinoxalinediones.
References Liu, P. et al.: ACS. Med. Chem. Lett., 2, 933 (2011); Bigge, C. et al.: J. Med. Chem., 38, 5720 (1995);

Applications 2,6-Dimethylphenanthrene have been used in investigating Polycyclic Aromatic Hydrocarbons Profiles in Higher Plants Using Statistical Models.
References Sojinu O., et al.: Int. J. Phytoremediat., 15, 439-451 (2013)

Applications tert-Butyl 6-amino-3,4-dihydroquinoline-1(2H)-carboxylate (cas# 1152923-36-8) is a useful research chemical.

Applications 5,6,7,8-TETRAHYDROISOQUINOLIN-1-AMINE (cas# 75704-51-7) is a useful research chemical.

Applications 4-NITROQUINOLINE N-OXIDE (cas# 56-57-5) is a useful research chemical.

Applications 2-(chloroacetyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (cas# 111631-72-2) is a useful research chemical.

Applications An indole derivative used in synthesis of matrix metalloprotease inhibitors.
References Somei, M., et al.: Nat. Prod. Rep., 22, 73 (2005),

Stability Hygroscopic
Applications 5-Bromo-4-chloro-3-indolyl caprylate (cas# 129541-42-0) is a useful research chemical.

Applications 5-Amino-8-fluoroquinoline is an intermediate for organic synthesis. It functions as a reagent in the preparation of pyridoquinolinones and pyridoquinolinecarboxylates as bactericides.
References Lee, J. K., et al.: Bull. Korean Chem. Soc., 17, 90 (1996)

Applications m-Toluquinoline is a reagent used in the preparation of diarylmethylpiperazines as potent opioid receptor agonists with improved side effects. Also used in the preparation of novel pyrazine compounds derived from 2-phenylquinolin-7-yl which act as potent insulin-like growth factor-I receptor inhibitors.
References Plobeck, N. et al.: J. Med. Chem., 43, 3878 (2000); Mulvihill, M. et al.: Bioorg Med. Chem. Lett., 16, 1359 (2008);

Applications 2-Amino-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 16321-99-6) is a compound useful in organic synthesis.

Applications 2,6-Dichloropurine-9-β-D-riboside (cas# 13276-52-3) is a compound useful in organic synthesis.

Applications 5-Cyano-2,3-dihydro-1H-indole

Applications 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester is used in the synthesis of antibacterials.
References Phillips, O. et al.: Exp. Opin. Ther. Pat., 19, 529 (2009);

Applications 5,6,7,8-Tetrahydroquinoline (cas# 10500-57-9) is a useful research chemical.

Applications 6-Bromo-3-cyanoindole

Applications 5,7-Dichloro-1,2,3,4-tetrahydro-2-(triphenylmethyl)-6-isoquinolinecarboxylic Acid, can be sued in the preparation of novel series of compounds which has been found to be a potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for treating dry eye.
References Zhong, M. et al,: ACS Med. Chem. Let. Vol. 3, page 203-206 (2012);

Applications 4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione (cas# 5488-36-8) is a useful research chemical.

Applications 2-[(Dimethylamino)methyl]indole (cas# 3978-16-3) is a compound useful in organic synthesis.
References Inion, H., et al.: Eur. J. Med. Chem., 10, 276 (1975),

Applications 2-chloro-1-{1H,2H,3H,4H,5H-pyrido[4,3-b]indol-2-yl}ethan-1-one (cas# 1087784-16-4) is a useful research chemical.

Applications 4,7-Dichloro-2-phenyl-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of phthalic compounds, phthalazines, and quinones with antimicrobial activity.
References Marriott, G. J., et al.: J. Chem. Soc., 134 (1939); Katayama, H., et al.: Tetrahedron., 63, 6642 (2007);

Applications 4,4'-Dicyano-2,2'-bipyridine is a photosensitizers for solar fuel generation
References Mills, I. N., et al.: Polyhedron, 82, 104 (2014)

Applications 4,4-Dimethyl-1,2,3,4-tetrahydroquinoline

Applications 2,3-dihydrobenzo[g]quinolin-4(1H)-one (cas# 21516-07-4) is a useful research chemical.

Applications 9,10-Phenanthrenequinone is used in the formation of spirophosphoranes containing acyclic 5-methyl-2-phenyl-2H-1,2,3-diazaphosphol-4-yl substituent.
References Mironov, V. F., et al.: Russ. J. Electrochem., 88, 430-438 (2018)

Applications Ethyl 2-Aminoindole-3-carboxylate (cas# 6433-72-3) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications 2-AMINO-1,2,3,4-TETRAHYDROISOQUINOLINE-1,3-DIONE (cas# 22177-46-4) is a useful research chemical.

Applications N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide is used in synthesis of an antitumor agent, neratinib (N390090).
References Zhang, P., et al.: Zhongguo Yaowu Huaxue Zazhi, 18, 355 (2008);

Applications 2,2'-Bipyridine-4,4'-dicarboxamide

Applications 2-(Chloroacetyl)isoindoline was used in the reaction with potassium thiocyanate to synthesize N-​(α-​Thiocyanatoacetyl)​indolines, which is useful as agricultural fungicides.
References Richter, S.: U.S. (1975), US 3929830 A 19751230.

Applications 2,6-Diazaspiro[3.3]heptane-2-carboxylic Acid tert-Butyl Ester Hemioxylate is preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for treatment of diseases.
References Katamreddy, S. R., et al.: PCT Int. Appl. (2020), WO 2020140055 A1

Applications Triclocarban Related Compound A (cas# 1219-99-4) is a useful research chemical.

Applications 2,2'-Bipyridyl-d8 was a useful compound in the NMR study of soft porous nanocrystal and a bulk crystal.
References Hijikata, Y., et al.: Chem. Commun. (Cambridge, UK), 47, 7632 (2011)

Applications 2-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 79999-39-6) is a compound useful in organic synthesis.

Stability Moisture Sensitive
Applications 1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-sulfonyl chloride (cas# 1240529-56-9) is a useful research chemical.

Applications 4-Acetoxyindole is a useful intermediate for organic synthesis of Psilocine and Psilocine analogs.
References Julia, M., et al.: Chimica Therapeutica, 5, 279 (1970); Repke, D. B., et al.: J. Heterocycl. Chem., 14, 71 (1977)

Stability Moisture Sensitive
Applications Isoquinoline-5-sulfonyl Chloride, Hydrochloride (cas# 105627-79-0) is a compound useful in organic synthesis.

Applications 3-Aminoquinoline-2-carboxylic acid (cas# 887245-74-1) is a useful research chemical.

Applications 7-Aminoindole

Applications 1H-Indole-d5-3-acetamide is the isotope labelled analogue of Indole-3-acetamide, a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants.
References Mano, Y., et al.: J. Exp. Bot., 61, 25 (2010);

Applications 9-oxo-9H-Thioxanthene-4-carboxylic acid (cas# 51762-56-2) is a useful research chemical.

Applications 5-Hydroxyquinoline-3-carboxylic acid (cas# 911108-90-2) is a useful research chemical.

Applications 4,8-DICHLOROQUINOLINE (cas# 21617-12-9) is a useful research chemical.

Applications 2-Oxa-7-azaspiro[3.5]nonane is an intermediate used to prepare benzothienoazepine derivatives as potent respiratory syncytial virus RNA polymerase inhibitors. It is also used to prepare 1,7-Diazacarbazole derivatives as inhibitors of checkpoint kinase 1.
References Xiong, H., et al.: Bioorg. Med. Chem. Lett., 23, 6789 (2013); Gazzard, L., et al.: J. Med. Chem., 58, 5053 (2015)

Applications 3-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-3,4-dihydro-5H-imidazo[2,1-i]purine-5-thione is used in the synthesis of azidoetheno analogs of deoxyadenosine as nucleotide photo-affinity probes.
References Flaherty, D. et al.: Nucleos. Nucleot., 14, 65 (1995);

Stability Hygrscopic
Applications 2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt

Applications Methyl quinoline-4-carboxylate (cas# 21233-61-4) is a useful research chemical.

Applications Ethyl 4,6,8-trichloroquinoline-3-carboxylate

Applications 6-Fluoroquinoline, is a versatile building block used in the synthesis of various chemical compounds.

Applications 2,6-Dichloro-9-nitroso-9H-purine is a compound useful in organic synthesis.

Applications 4-Hydroxy-quinoline-6-carboxylic acid