Organic Building Blocks

Applications Bis(4-diethylaminophenyl)methanol (cas# 134-91-8) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N-Boc Gatifloxacin is an intermediate used in the synthesis of Gatifloxacin N-Oxide (G250005), which is an impurity of Gatifloxacin (G250000), an antibacterial agent.
References Bauernfeind, A.: J. Antimicro. Chemother., 40, 639 (1997), Fukuda, H., et al.: Antimicrob. Ag. Chemother., 42, 1917 (1998),

Applications c-GpAp induces the production of interferons, a usual response to triggers in the cytoplasm of mammalian cells by the presence of DNA.
References Sun, L. et al.: Science, 339, 786 (2013);

Applications 3,6-Dimethyl-3-heptanol (cas# 1573-28-0) is a compound useful in organic synthesis.

Applications Methanesulfonylacetic acid (cas# 2516-97-4) is a useful research chemical.

Applications PD-146176 is a potent and selective 15-LO inhibitor.

Applications (S,S)-(-)-Hydrobenzoin is a chral auxiliary with versatile applications. It is also used as a building block.
References Marshall, J., et al.: J. Org. Chem. 60, 7230 (1995); Stolle, A., et al. Tetrahedron Lett. 35, 3521 (1994); Burk, M., et al.: J. Am. Chem. Soc. 115, 10125 (1993); Burk, M., et al.: Tetrahedron Asymmetry 2, 569 (1991); Pichon, M., et al: Tetrahedron Asymmetry 7, 927 (1996)

Applications Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate is a useful synthetic intermediate in the synthesis of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase (DPP) IV inhibitor for the treatment of type II diabetes.
References Liu, F., et al.: J. Chem. Res., 34, 230 (2010); Ahn, J. H., et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007); Hansen, K. B., et al.: Org. Process Res. Dev., 9, 634 (2005)

Applications Methanesulfonic anhydride is a reagent that is used in the synthesis of (R)-Amino Carnitine (A603400), which is an inhibitor of fatty acid oxidation.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jenkins, D.L., et al.: J. Biol. Chem., 260, 14748 (1985), Kanamaru, T., et al.: M. Life Sci., 37, 217 (1985), Hulsmann, W.C., et al.: J. Biochim. Biophys. Acta., 1097, 263 (1991), Chiodi, P., et al.: Biochim, Biophys. Acta., 1127, 81 (1992),

Applications 2-(tert-Butoxy)-2-oxoethyl 2-cyclohexyl-2-hydroxy-2-phenylacetate is an intermediate in the synthesis of 2-(2-Cyclohexyl-2-hydroxy-2-phenylacetyloxy)acetic Acid (C988080) which is an impurity of Oxybutynin (O868525), an inhibitor of proliferation and gene expression in bladder smooth muscle cells.
References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)

Applications Euscaphic Acid is a hypoglycemic natural product from Folium Eriobotryae with anti-inflammatory properties. Euscaphic Acid also downregulates NF-κB activations and inhibits LPS-induced inflammatory responses.
References Chen, J., et al.: Pharmazie. 63, 765 (2008); Kim, I. T., et al.: J Cell Biochem. 113, 1936 (2012)

Stability Air Sensitive, Light Sensitive
Applications 4-Toluidine-d7 is an isotopically labeled research compound of 4-Toluidine (T536210) which is compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 7-Hydroxyquinoline-6-carboxylic Acid is a useful research compound.

Applications N,N',N''-Tris(2-hydroxyethyl)phosphorothioic Triamide is a useful intermediate for organic synthesis.

Applications Bicyclo[1.1.1]pentan-1-amine is a reagent useful in a variety of synthesis. In particular, it is used in the prepartion of 2,4-diaminopyrimidines which are histamine H4 receptor ligands.
References Bell, A. S. et al.: PCT Int. Appl. 85 pp. (2007)

Stability Hygroscopic
Applications 4-O-Methyl-D-glucuronic acid (cas# 2463-49-2) is a useful research chemical.

Applications 2-PHENYLNICOTINIC ACID (cas# 33421-39-5) is a useful research chemical.

Applications A useful synthetic intermediate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Mercaptoisobutyric Acid, 90% (cas# 4695-31-2) is a compound useful in organic synthesis.
References McIntosh, J.M. and Siddiqui, M.A.: Can. J. Chem., 61, 1872-1875 (1983), Bienlarz, C. and Cornwall, M.J.: Tetrahedron Lett., 34 (6), 939-942 (1993)

Applications Dimethyl Hexanedioate-d8 (CAS# 52089-64-2) is a useful isotopically labeled research compound.

Applications DP-1 is a reagent used in the metal-catalyzed and highly enantioselective formation of complex pyrazolone derivatives.
References Tao, Z., et. al.: J. Am. Chem. Soc., 135, 9255 (2013);Wang, Z., et. al.: Angew. Chem. Int. Ed. Engl., 50, 4928 (2011);Yang, Z., et. al.: Org. Lett., 13, 596 (2011)

Applications N-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles.
References Lee, D. H., et al.: PCT Int. Appl. 23 pp. (2019)

Applications 4-(4-Methylpiperazin-1-ylmethyl)Benzoic Acid (cas# 106261-48-7) is a useful research chemical.

Applications 3-Methylpentanedioic-2,2,4,4-d4 Acid (CAS# 1219798-68-1) is a useful isotopically labeled research compound.

Applications n-Dodecyl-d25-trimethylammonium Bromide is a useful isotopically labeled compound of Dodecyltrimethylammonium BromideDISCONTINUED PLEASE SEE D525490 (D525740)

Applications 2,2'-Ethylenedianiline is used as a reagent to synthesize Oxcarbazepine (O869250), a broad-specturm, second-generation anticonvulsant drug that is used to treat partial and complex partial seizures in children and adults. 2,2'-Ethylenedianiline is also used as a reagent to prepare a series of triterpines (e.g. Lupeol [L474850]), compounds that have chemopreventative activity.
References Asmaa, M., et al.: Pac. J. Cancer Prevent., 15, 475 (2014); Kalis, M. & Huff, N.: Clin. Ther., 23, 680 (2001); Malke, S., et al.: Pharm. Sci., 69, 211 (2007); Schmidt, D. & Elger, C.: Epil. Beh., 5, 627 (2004)

Applications N-Nervonoyl Taurine is a metabolite from an active fraction of Cajanus cajan seeds which could be an antioxidant.
References Tekale, S., et al.: Food Chem., 211, 763-769 (2016)

Applications Fmoc-​Leu-​OH-13C6,15N is a useful reagent in the preparation of heavy isotopic form of the FCAT reagents and its use in labeling of tryptic peptides.
References Rivera-Monroy, Z., et al: Electrophoresis, 30, 1111 (2009)

Applications Acetyl Brimonidine is used as a reagent in the synthetic preparation of Brimonidine derivatives.Brimonidine is an Antiglaucoma drug.
References Naik, A. M., et al.: Int.J. PharmTech Res. 2, 14 (2010); Cantor, L. B., Expert Opin. Pharmacother., 1, 815 (2000)

Applications This compound is used in preparation and esterification reaction of  Papaverine derivative with pentanediol.
References Ivanov, T., et al.: Eur. Pat. Appl., (1986);

Applications 2,2'-Dimethyl-[1,1'-biphenyl]-4,4'-diamine (cas# 84-67-3) is a useful reagent for manufacturing cured films and semiconductor devices.
References Aoshima, T., et al.: PCT Int. Appl. (2020), WO 2020226131 A1

Applications 5-methylnicotinamide (cas# 70-57-5) is a useful research chemical.

Applications 2-Amino-6-methoxybenzothiazole is an intermediate used to prepare novel series of Schiff bases and 4-thiazolidinones. It is also used in the synthesis of 2-cyano-6-methoxybenzothiazole.
References Patel, N., et al.: Saudi Pharma. J., 18, 129 (2010); Toya, Y., et al.: Bull. Chem. Soc. Jpn., 65, 392 (1992)

Applications: TSTU is used as a peptide coupling reagent in solvent systems.
References Knorr, R., et. al.: Pept. 1990, Proc. Eur. Pept. Symp., 21st, 62-4 (1991)

Stability Hygroscopic
Applications (4-Methoxybenzyl)hydrazine Hydrochloride is used in preparation of Heterocyclic derivatives useful as SHP2 inhibitors.
References Kang, D., et al.: PCT Int. Appl., (2020);

Applications 2-Pyridineacetonitrile is a useful reagent for the organic synthesis and studies of pyridyl and dihydropyridyl analogs of meperidine and ketobemidone with their antinociceptive activities.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Buolamwini, J. K., et al.: Drug Des. Deliv., 7, 19 (1990)

Applications 3-(3-Hydroxy-1-piperidinyl)-1,2-propanediol is a compound useful in organic synthesis.

Applications Physcion 8-β-D-glucoside has been studied in research relating to the treatment of the glomerulonephritis. It is the glucoside of Physcion (P398000) which is a natural anthraquinone derivative, on the infection process of Blumeria graminis on wheat. Physcion is one of the important active ingredients of ethanol extract from the roots of Chinese rhubarb (Rheum officinale) for controlling powdery mildew.
References Kuo, Y.C. et al.: Life. Sci., 68, 1271 (2001); Thiericke, R., et al.: Nat. Prod. Rep.,10, 265 (1993); Lin, C., et al.: J. Nat. Prod., 58, 1934 (1995); Julia, S., et al.: J. Biotechnol., 124, 690 (2006); Wang, W., et al.: J. Antibiot., 60, 603 (2007);

Applications trans-Cinnamic-alpha,2,3,4,5,6-d6 is a useful isotopically labeled compound of (2E)-3-Phenyl-2-propenoic Acid (P336185)

Stability Hygroscopic

Applications N,N’-Methylenebis(acrylamide)-d6 is the isotope labelled analog of N,N’-Methylenebis(acrylamide) (M303745); a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel (1,2,3).
References (1) Julien, C., et al.: Methods in Mol. Bio., 849, 473 (2012) (2) Suedee, R., et al.: J. Chromat. A, 1114, 239 (2006)(3) Olding, T., et al.: J Med Phys. 36, 3 (2011)

Applications 2-METHOXYNICOTINIC ACID (cas# 16498-81-0) is a useful research chemical.

Stability Store at -20°C under Argon. Air Sensitive.
Applications 5,5-Diethoxypentanal (cas# 79893-96-2) is a compound useful in organic synthesis.

Applications 2-(methylamino)-6,7-dihydro-3H-purin-6-one (cas# 10030-78-1) is a useful research chemical.

Applications N-Methyl-D3-pyrrolidine is a labelled analogue of N-Methylpyrrolidine, a compound that is used as a base in synthetic chemistry. N-Methylpyrrolidine has also been known to exert a Nicotine(N412420)-like effect on isolated smooth muscle preparations.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kim, K., et al.: J. Pharmacol. Exp. Ther., 161, 59 (1968); Ogawa, A., et al.: Tetrahedron Lett., 28, 3271 (1987)

Applications Ethanol-1,1,2,2-d4-amine HCl is a useful isotopically labeled compound of 2-Aminoethanol Hydrochloride (A576798)

Applications 2-​Aminoindan-​2-​carboxylic Acid can be used as a potential tyrosine hydroxylase inhibitor.
References Pinder, R., et al.: J. Med. Chem., 14, 892 (1971)

Applications N,N-Dimethylethanolamine-d10 (OH) is a useful isotopically labeled compound of 2-Dimethylaminoethanol (D471170)

Applications N-Methoxy-N-methyldodecamide is an intermediate in the synthesis of 12-Pentacosanone (P270260). 12-Pentacosanone is a useful research chemical for organic synthesis and other chemical processes.
References Holleman, L. W. J., et al.: Recl. Trav. Chim. Pays-Bas., 58, 666 (1939); Azerad, R., et al.: Biochimie, 54, 271 (1972)

Applications 3-(1H-indol-5-yl)propanoic acid (cas# 192717-19-4) is a useful research chemical.

Applications (2S)-pentan-2-amine hydrochloride (cas# 216237-52-4) is a useful research chemical.

Applications Methyl 5-Methyl-3-phenyl-4-isoxazolecarboxylate-d5 is an intermediate in the synthesis of Oxacillin Sodium-d5 Salt (O758502); Isotope labelled Oxacillin Sodium Salt is a semi-synthetic antibiotic related to Penicillin. Antibacterial.
References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),

Applications 1,2-Dimethylcyclohexane is used in the preparation of rhodium nanoparticles as recyclable catalysts.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Stratton, S.A., et. al.: Catalysis Today, 183, 96 (2012)

Applications 2-Methyl-d3-2-hexanol-1,1,1,3,3-d5 is a useful isotopically labeled compound of 2-Methyl-2-hexanol (M331848)

Applications An intermediate in the preparation of pharmaceutically active Cyproheptadines.
References Thompson, W., et al.: J. Med. Chem., 33, 789 (1990),

Applications Reagent used in the preparation of pharmaceutically active Dibenzocyclohenptenes.

Applications [3-(Dodecyloxy)-2-hydroxypropyl]diethyl[2-[(1-oxoallyl)oxy]ethyl]ammonium Chloride is a useful reasearch chemical.

Applications GUANIDINE PHOSPHATE (cas# 5423-23-4) is a useful research chemical.

Applications 5-​Methyl-​2,​4-​dinitrobenzene-​1-​sulfonic Acid is an impurity in the treatment of 2,4,6-trinitrotoluene (TNT),an exoplosive material.
References Zhang, M. et al.: Chem. Eng. J., 259, 876 (2015);