Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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Carotegrast
CAS:<p>Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.</p>Formula:C27H24Cl2N4O5Color and Shape:SolidMolecular weight:555.41Synstatin (92-119)
CAS:<p>Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and</p>Formula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27THK-5105
CAS:<p>THK-5105, a tau-binding arylquinoline, could be an 18F-PET imaging probe for Alzheimer's disease.</p>Formula:C20H21FN2O2Color and Shape:SolidMolecular weight:340.39EG-011
CAS:<p>EG-011, a potent first-in-class WASP activator, enhances actin polymerization, showing selective anti-tumor effects in lymphomas.</p>Formula:C28H26N4O4Color and Shape:SolidMolecular weight:482.53Gly-Arg-Gly-Asp-Ser TFA
CAS:<p>Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.</p>Formula:C19H31F3N8O11Color and Shape:SolidMolecular weight:604.49Pin1 modulator 1
CAS:<p>Pin1 modulator 1 (compound IIb-219) is a specific β-Catenin targeting agent that inhibits the Wnt pathway and is applicable in researching Wnt-mediated diseases, including cancer [1].</p>Formula:C18H15NO3S2Color and Shape:SolidMolecular weight:357.44β-Catenin modulator-3
CAS:<p>β-Catenin modulator-3 (compound IIa-112), an oxazole and thiazole-based chemical entity, serves as a potent and selective modulator of β-Catenin [1].</p>Formula:C21H22N2O3SColor and Shape:SolidMolecular weight:382.483CAI
CAS:<p>3CAI inhibits AKT1/2, reduces mTOR/GSK3β, and triggers apoptosis in colon cancer cells.</p>Formula:C10H8ClNOPurity:98.13%Color and Shape:SolidMolecular weight:193.63Pterostilbene-isothiocyanate
CAS:<p>Pterostilbene-isothiocyanate (PTER-ITC) demonstrates strong anticancer properties in vitro, particularly disrupting the interaction between β-catenin and TCF-4</p>Formula:C18H19N3O3SColor and Shape:SolidMolecular weight:357.43AT7867 hydrochloride
CAS:<p>AT7867 hydrochloride is a potent inhibitor of AKT and p70 S6 kinase, displaying oral activity and demonstrating an anticancer effect [1].</p>Formula:C20H21Cl2N3Color and Shape:SolidMolecular weight:374.31α7β1 integrin modulator-1
CAS:<p>α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].</p>Formula:C23H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:475.56Lotrafiban
CAS:<p>Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.</p>Formula:C23H32N4O4Color and Shape:SolidMolecular weight:428.52L-739758
CAS:<p>L-739758 is a glycoprotein IIb/IIIa inhibitor.</p>Formula:C22H26N4O5S3Color and Shape:SolidMolecular weight:522.66PVZB1194
CAS:<p>PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through</p>Formula:C13H9F4NO2SPurity:98%Color and Shape:SolidMolecular weight:319.28BCR-ABL-IN-4
CAS:<p>BCR-ABL-IN-4: Anticancer BCR-ABL inhibitor; stops K562 cells (IC50: 0.67 nM), targets T315I Ba/F3 cells (IC50: 16 nM).</p>Formula:C27H24ClF2N5O4Color and Shape:SolidMolecular weight:555.96β-catenin-IN-4
CAS:<p>β-Catenin-IN-4 is a β-catenin inhibitor characterized by a K_i value of 0.64 μM.</p>Formula:C38H33ClF3N5O9Color and Shape:SolidMolecular weight:796.14SB-743921 free base
CAS:<p>SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).</p>Formula:C31H33ClN2O3Purity:98%Color and Shape:SolidMolecular weight:517.06SEN461
CAS:<p>SEN461 is a wnt inhibitor.</p>Formula:C25H34N4O6Purity:98%Color and Shape:SolidMolecular weight:486.56Heclin
CAS:<p>Heclin is an inhibitor of HECT E3 ubiquitin ligase that acts by inhibiting Smurf2, Nedd4, and WWP1 with IC50 values of 6.8, 6.3, and 6.9 μM, respectively.</p>Formula:C17H17NO3Purity:95.79%Color and Shape:SolidMolecular weight:283.32(-)-Indolactam V
CAS:<p>(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.</p>Formula:C17H23N3O2Purity:98%Color and Shape:SolidMolecular weight:301.38Antitumor agent-86
CAS:<p>Antitumor agent-86 targets MCF-7 cells with 2.62 µM IC50, induces apoptosis, and disrupts RAS/PI3K/Akt/JNK pathways.</p>Formula:C29H31N5O2SPurity:98%Color and Shape:SolidMolecular weight:513.65Demethylasterriquinone B1
CAS:<p>insulin receptor (IR) activator</p>Formula:C32H30N2O4Purity:98%Color and Shape:SolidMolecular weight:506.59HSP90-IN-19
CAS:<p>HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.</p>Formula:C29H38O7Purity:98%Color and Shape:SolidMolecular weight:498.61Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2
CAS:<p>Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 demonstrates serum stability and non-toxicity to neuronal cells, while selectively inhibiting the fibrilization of tau in</p>Formula:C38H65N11O9Color and Shape:SolidMolecular weight:819.9922-(4′-py)-JA
CAS:<p>22-(4′-py)-JA, a semisynthetic derivative of junamycin A isolated from the Thai blue sponge (Xestospongia sp.), exhibits antimetastatic properties by inhibiting</p>Formula:C32H30N4O8Purity:98%Color and Shape:SolidMolecular weight:598.6PBB3
CAS:<p>PBB3 is a tau-specific PET tracer.</p>Formula:C17H15N3OSColor and Shape:SolidMolecular weight:309.39PKC-θ inhibitor 1
CAS:<p>PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)</p>Formula:C17H15F3N4OPurity:98%Color and Shape:SolidMolecular weight:348.32L 738167
CAS:<p>L 738167 is a potent antagonist of the long-acting fibrinogen receptor.</p>Formula:C25H34N6O6SColor and Shape:SolidMolecular weight:546.64TC-I 15
CAS:<p>α2β1 integrin inhibitor</p>Formula:C23H28N4O6S2Purity:98%Color and Shape:SolidMolecular weight:520.62SC-52012
CAS:<p>SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.</p>Formula:C25H30N4O6Purity:97.20%Color and Shape:SolidMolecular weight:482.53Lamifiban
CAS:<p>Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.</p>Formula:C24H28N4O6Purity:98%Color and Shape:SolidMolecular weight:468.5KU-177
CAS:<p>KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.</p>Formula:C27H23NO8Purity:96.92% - 98.54%Color and Shape:SolidMolecular weight:489.47IWP 12
CAS:<p>IWP 12 is a potent inhibitor of porcupine (Porcn), blocking Wnt signaling and inhibiting fin regeneration in adult and juvenile fish.</p>Formula:C18H18N4O2S3Purity:98.88%Color and Shape:SolidMolecular weight:418.56BIO-7662
CAS:<p>BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.</p>Formula:C38H48N6O8SPurity:98%Color and Shape:SolidMolecular weight:748.89Solenopsin
CAS:<p>Solenopsin is an ATP-competitive inhibitor of AKT(IC50 : 10 μM) .</p>Formula:C17H35NPurity:98%Color and Shape:SolidMolecular weight:253.47Palmitic acid calcium
CAS:<p>Calcium palmitate, a long-chain saturated fatty acid prevalent in animals and plants, induces the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells. It is employed to establish a cell steatosis model [1] [2].</p>Formula:C16H32O2CaColor and Shape:SolidMolecular weight:275.463-Hydroxyxanthone
CAS:<p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>Formula:C13H8O3Purity:98%Color and Shape:SolidMolecular weight:212.2MK-6240
CAS:<p>MK-6240: A tau PET tracer with high specificity for NFTs binding.</p>Formula:C16H11FN4Purity:98%Color and Shape:SolidMolecular weight:278.28NTRC 0066-0
CAS:<p>NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.</p>Formula:C33H39N7O2Purity:98.30%Color and Shape:SolidMolecular weight:565.71HDAC-IN-55
CAS:<p>HDAC-IN-55(8j) is a small-molecule inhibitor that enhances E-cadherin expression and suppresses cancer cell proliferation [1].</p>Formula:C17H17N3O3Purity:98%Color and Shape:SolidMolecular weight:311.34Levocabastine hydrochloride
CAS:<p>Levocabastine HCl is an agent with antihistaminic activity.</p>Formula:C26H30ClFN2O2Color and Shape:SolidMolecular weight:456.98TRV-1387
CAS:<p>TRV-1387, a benzofurazan derivative, inhibits the aggregation of tau and amyloid-β [1].</p>Formula:C23H25F3N4O2Color and Shape:SolidMolecular weight:446.47Kif15-IN-2
CAS:<p>Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.</p>Formula:C20H20N6O4SPurity:98.17%Color and Shape:SolidMolecular weight:440.48CT-721
CAS:<p>CT-721: potent, time-bound Bcr-Abl inhibitor, IC50 21.3 nM, effective against CML.</p>Formula:C30H29ClN6OPurity:98%Color and Shape:SolidMolecular weight:525.04TCS 21311
CAS:<p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.</p>Formula:C27H25F3N4O4Purity:99.39% - ≥98%Color and Shape:SolidMolecular weight:526.51HSP90-IN-27
CAS:<p>HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].</p>Formula:C18H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:343.44Ifebemtinib
CAS:<p>Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.</p>Formula:C28H28F4N6O4Purity:98.84% - 99.85%Color and Shape:SolidMolecular weight:588.55UCL-TRO-1938
CAS:<p>UCL-TRO-1938 is a subtype-selective PI3Kα allosteric activator with cardioprotective and neuroregenerative effects.</p>Formula:C27H32N6OPurity:99.95%Color and Shape:SolidMolecular weight:456.58αvβ1 integrin-IN-1
CAS:<p>αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.</p>Formula:C26H34N6O6SPurity:99.74% - >99.99%Color and Shape:SolidMolecular weight:558.65CFI-402257
CAS:<p>CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.</p>Formula:C28H30N6O3Purity:96.66% - 99.51%Color and Shape:SolidMolecular weight:498.58M2698
CAS:<p>M2698 (MSC2363318A) is an inhibitor of p70S6K, Akt1 and Akt3 with IC50s of 1 nM. M2698 shows anti-cancer activity.</p>Formula:C21H19ClF3N5OPurity:99.88%Color and Shape:SolidMolecular weight:449.86Roxifiban acetate
CAS:<p>Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used in</p>Formula:C23H33N5O8Purity:97.91% - 98.36%Color and Shape:SolidMolecular weight:507.54Zamaporvint
CAS:<p>Zamaporvint (RXC004) , a Wnt pathway inhibitor with antitumor and antiproliferative activity, blocks Wnt ligand palmitoylation and secretion.</p>Formula:C21H16F3N7OPurity:97.5%Color and Shape:SolidMolecular weight:439.39Gossypolone
CAS:<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Formula:C30H26O10Purity:96.66%Color and Shape:SolidMolecular weight:546.52GNF-6231
CAS:<p>GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.</p>Formula:C24H25FN6O2Purity:99.74% - >99.99%Color and Shape:SolidMolecular weight:448.49ATM-3507
CAS:<p>ATM-3507 is an inhibitor of tropomyosin. In human melanoma cell lines, the IC50s are from 3.83-6.84 μM.</p>Formula:C37H46FN5O2Purity:96.77% - 98.81%Color and Shape:SolidMolecular weight:611.79PKC-IN-1
CAS:<p>PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,</p>Formula:C25H37FN8O2Purity:98% - 98.79%Color and Shape:SolidMolecular weight:500.61AMXI-5001 hydrochloride
<p>AMXI-5001 hydrochloride, an oral inhibitor of PARP1/2 and microtubules, shows greater potency and selective anti-cancer effects.</p>Formula:C25H21ClFN5O3Color and Shape:SolidMolecular weight:493.92Tubulin inhibitor 16
<p>Tubulin inhibitor 16 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 16 exhibits cytotoxicity in HepG2 cells [1].</p>Formula:C16H12FNO2Color and Shape:SolidMolecular weight:269.27AKT-IN-10
CAS:<p>AKT-IN-10, a potent AKT inhibitor, has potential for breast and prostate cancer research, impacting cell growth and survival pathways.</p>Formula:C26H34ClN5O2Color and Shape:SolidMolecular weight:484.03TTBK1/2-IN-1
CAS:<p>TTBK1/2-IN-1 (compound 3) is a potent inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 816 nM and 384 nM, respectively.</p>Formula:C17H16N4OColor and Shape:SolidMolecular weight:292.335Hsp90-IN-34
CAS:<p>Hsp90-IN-34 (compound HAM-1) is a chemical inhibitor that targets the Aha1-Hsp90 chaperone complex with high affinity (KDapp=23.5 µM). It modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1.</p>Formula:C22H14F2N6OColor and Shape:SolidMolecular weight:416.38Tubulin polymerization-IN-75
CAS:<p>Tubulin polymerization-IN-75 (Compound 6) is an inhibitor of tubulin polymerization, with an IC50 value of 30 μM. It effectively suppresses the proliferation of cancer cells Huh7 and 293T, demonstrating IC50 values of 14.3 μM and 13.8 μM, respectively.</p>Formula:C14H11NOColor and Shape:SolidMolecular weight:209.243DCEM1
CAS:<p>DCEM1 binds to heat shock protein 60 (HSP60) and inhibits the interaction between HSP60 and ClpP, thereby blocking the mitochondrial unfolded protein response. Additionally, DCEM1 suppresses the expression of β-catenin and reduces ATP production in PC-3 and TKO cells. It is utilized in research related to prostate cancer.</p>Formula:C22H23N3O2SColor and Shape:SolidMolecular weight:393.50FAK inhibitor 7
CAS:<p>FAK inhibitor7, a potent FAK inhibitor, demonstrates an IC50 of 3.58 nM. This compound effectively inhibits downstream signaling cascades of FAK (such as Src and AKT), which leads to cell cycle arrest at the G0/G1 phase and induces cytotoxic autophagy in ovarian cancer cells. Additionally, FAK inhibitor7 has been shown to suppress tumor metastasis and growth in ovarian cancer mouse models.</p>Formula:C32H37N7O3Color and Shape:SolidMolecular weight:567.68Dictyostatin
CAS:<p>Dictyostatin: potent microtubule stabilizer & anticancer agent with antiproliferative effects; researched for tauopathies.</p>Formula:C32H52O6Color and Shape:SolidMolecular weight:532.75OXA-11
CAS:<p>OXA-11 (FAK-IN-16) is a FAK inhibitor with anti-tumor activity, useful for cancer research.</p>Formula:C37H49F3N7O5PPurity:98.70% - 99.20%Color and Shape:SolidMolecular weight:759.8Uprosertib hydrochloride
CAS:<p>Uprosertib hydrochloride is a potent and selective inhibitor of pan-Akt (IC50: 180/328/38 nM for Akt1/Akt2/Akt3, respectively).</p>Formula:C18H17Cl3F2N4O2Purity:98%Color and Shape:SolidMolecular weight:465.71AMG28
CAS:<p>AMG28 is an inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 805 nM and 988 nM, respectively. Additionally, AMG28 suppresses the phosphorylation of tau protein at the Ser422 site, with an IC50 of 1.85 μM.</p>Formula:C20H20N4OColor and Shape:SolidMolecular weight:332.399Tubulin inhibitor 19
<p>Tubulin inhibitor 19 (9b), a potent indole chalcone, strongly blocks tubulin, valuable in cancer studies.</p>Formula:C21H23NO5Color and Shape:SolidMolecular weight:369.41PKCTheta-IN-2
CAS:<p>PKCTheta-IN-2 (compound 14) is a potent and selective inhibitor of PKCθ, with an IC50 value of 0.25 nM. It demonstrates good selectivity across a broad range of kinases, including the PKC subfamily (30 kinases). Additionally, PKCTheta-IN-2 effectively inhibits the production of IL-2 in mice, where it exhibits an IC50 of 682 nM.</p>Formula:C24H23N5O2Color and Shape:SolidMolecular weight:413.47Lisavanbulin
CAS:<p>Lisavanbulin (BAL-101553) is a prodrug of Avanbulin (BAL 27862), a microtubule-targeting agent. It exhibits antitumor activity, particularly effective against tumors with high expression of end-binding protein 1.</p>Formula:C26H29N9O3Color and Shape:SolidMolecular weight:515.57PI3K-IN-29
CAS:<p>PI3K-IN-29: Strong PI3K block, inhibits Akt phosphorylation. IC50: U87MG 0.264µM, HeLa 2.04µM, HL60 1.14µM.</p>Formula:C27H22ClN7O3SColor and Shape:SolidMolecular weight:560.03Tubulin polymerization-IN-32
<p>Tubulin polymerization-IN-32: a cancer cell growth inhibitor used for research in cancers like lymphoma.</p>Formula:C29H30N2O7Color and Shape:SolidMolecular weight:518.56Hsp90-IN-37
CAS:<p>Hsp90-IN-37 (Z-2) is an inhibitor of heat shock protein 90 (Hsp90), demonstrating a 69% inhibition rate on Hsp90 enzyme activity. It exhibits antitumor properties.</p>Formula:C12H15N3O2Color and Shape:SolidMolecular weight:233.266L 734217
CAS:<p>L 734217 is an antagonist of the fibrinogen receptor.</p>Formula:C18H31N3O4Purity:98%Color and Shape:SolidMolecular weight:353.46EV206
CAS:<p>EV206 is an effective inhibitor of Hsp70, exhibiting antiproliferative properties. This compound induces cell apoptosis (apoptosis) and enhances the protein expression of cleaved PARP and caspase-3. Additionally, EV206 demonstrates antitumor activity.</p>Formula:C21H19N3OColor and Shape:SolidMolecular weight:329.40Tubulin inhibitor 22
<p>Compound 4c: Strong tubulin inhibitor with anti-cancer & anti-angiogenic effects; halts MGC-803 cells in G2/M, triggers Caspase-mediated apoptosis.</p>Formula:C20H17BrFNO4Color and Shape:SolidMolecular weight:434.26PROTAC α-synuclein degrader 6
CAS:<p>PROTACα-synuclein degrader 6 (compound T3) is a PROTAC degrader of α-synuclein and tau, with an EC50 of 1.57 μM and 4.09 μM, respectively. This compound plays a significant role in neurodegenerative disease (ND) research.</p>Formula:C37H39N5O9SMolecular weight:729.80FPDT
<p>FPDT combats glioblastoma by inhibiting the AKT pathway; IC50: >100 μM (astrocytes), 45-68 μM (GBM cells).</p>Formula:C16H12FNO2SColor and Shape:SolidMolecular weight:301.34Tubulin polymerization-IN-63
CAS:<p>Tubulin polymerization-IN-63 (compound 6) is an inhibitor of tubulin polymerization. It exhibits an IC50 value of 0.29 μM against MES-SA cells, making it suitable for use in cancer research.</p>Formula:C20H24ClCuN5O2SColor and Shape:SolidMolecular weight:497.5EX05
CAS:<p>EX05, an effective KIF18A inhibitor, exhibits an IC50 of 8.2 nM and holds potential for cancer research applications.</p>Formula:C26H30F2N4O5SColor and Shape:SolidMolecular weight:548.60Tubulin polymerization-IN-34
<p>"Tubulin-IN-34 inhibits oxazolylisoindole microtubule assembly, selective for VL51 lymphoma."</p>Formula:C31H35N3O6Color and Shape:SolidMolecular weight:545.63Tubulin polymerization-IN-74
CAS:<p>Tubulin polymerization-IN-74 (compound 11) is an inhibitor of tubulin polymerization, with an IC50 value of 15 μM. It is applicable to cancer research.</p>Formula:C14H11NSColor and Shape:SolidMolecular weight:225.309DDO-6691
CAS:<p>DDO-6691 is an inhibitor of heat shock protein 90 (HSP90). It exhibits antiproliferative effects against various tumor cells, with the highest sensitivity observed in HCT-116 colon cancer cells (IC50: 1.08 μM). DDO-6691 also demonstrates potent tumor growth inhibition in HCT-116 xenograft mouse models.</p>Formula:C22H17N3O2SColor and Shape:SolidMolecular weight:387.45Latrunculins A
CAS:<p>Latrunculins A is a novel marine toxin, disrupts microfilament organization in cultured cells.</p>Formula:C22H31NO6SColor and Shape:SolidMolecular weight:437.55Macbecin I
CAS:<p>Hsp90 inhibitor</p>Formula:C30H42N2O8Purity:98%Color and Shape:SolidMolecular weight:558.66Cemdomespib
CAS:<p>Cemdomespib (KU-596) is a potent Hsp90 modulator with neuroprotective effects and can improve diabetic neuropathy.</p>Formula:C24H30FNO6Color and Shape:SolidMolecular weight:447.5AKT-IN-11
<p>AKT-IN-11 is one of the most potent antibacterial agents against human hepatocellular carcinoma Bel-7402 cell line (IC50: 1.15 μM).</p>Formula:C27H27ClF3NO4Color and Shape:SolidMolecular weight:521.96Wikstrol A
CAS:<p>Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.</p>Formula:C30H22O10Color and Shape:SolidMolecular weight:542.49Tubulin inhibitor 15
<p>Tubulin inhibitor 15 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 15 exhibits cytotoxicity in HepG2 cells [1].</p>Formula:C16H12FNO2Color and Shape:SolidMolecular weight:269.27HG-7-86-01
CAS:<p>HG-7-86-01 is a selective type II tyrosine kinase inhibitor with antiproliferative activity against mutant T315I- Bcr-Abl for chronic myeloid leukemia (CML).</p>Formula:C28H21F3N6O2SPurity:99.07%Color and Shape:SolidMolecular weight:562.57ZLY06
CAS:<p>ZLY06 is a dual agonist of peroxisome proliferator-activated receptors (PPAR) δ and γ with oral activity (PPAR δ: EC50=341 nM; PPARγ: EC50=237 nM). It mediates the upregulation of CD36 and induces hepatic lipid accumulation by inhibiting the phosphorylation of AKT1. Moreover, ZLY06 significantly improves glucose and lipid metabolism without increasing body weight, primarily by enhancing the β-oxidation of fatty acids and reducing hepatic lipid synthesis, thereby alleviating fatty liver disease.</p>Formula:C25H26O6Color and Shape:SolidMolecular weight:422.47GSD-11
<p>GSD-11: Potent, selective anti-austerity agent; blocks Akt/mTOR pathway, hinders PANC-1 cell migration & colony growth. Promising for pancreatic cancer study.</p>Formula:C20H28O2Color and Shape:SolidMolecular weight:300.44HSP90α-IN-1
CAS:<p>HSP90α-IN-1 is an HSP90α inhibitor (IC50= 111 nM) that demonstrates anti-aging activity across various cellular senescence models. Belonging to the xanthine family, HSP90α-IN-1 is involved in research focused on combating age-related inflammation, senescence, and diseases (including cancer), and it may contribute to extending healthy lifespan.</p>Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.356G-9791
CAS:<p>G-9791 is an effective and selective inhibitor of group-I PAK.</p>Formula:C26H26ClFN6O2Purity:98%Color and Shape:SolidMolecular weight:508.98Mps1-IN-8
CAS:<p>Mps1-IN-8, a Mps1 inhibitor, can be utilized in the study of various tumors [1].</p>Formula:C35H47N8O6PColor and Shape:SolidMolecular weight:706.77Dioleyl phosphatidylserine
CAS:<p>Dioleyl phosphatidylserine is a phospholipid that can activate PKC-γ (Protein Kinase C-gamma) when the Ca2+ concentration is below 0.5 μM, specifically at a concentration of 100 μM.</p>Formula:C42H78NO10PColor and Shape:SolidMolecular weight:788.04HSP90-IN-32
CAS:<p>HSP90-IN-32, a carboxy-terminus inhibitor of Hsp90C, exhibits antiproliferative activity in various cell lines including SKMel173, SKMel103, SKMel19, and A375, with IC50 values of 1.01 μM, 0.782 μM, 0.607 μM, and 1.413 μM, respectively. This compound holds potential for research in anticancer agents.</p>Formula:C33H40N2O4Color and Shape:SolidMolecular weight:528.68FAK-IN-21
CAS:<p>FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.</p>Formula:C22H22F2N8O3SColor and Shape:SolidMolecular weight:516.52
