Deuterated Compounds

Applications 1,3-Diethylbenzene-d14 (CAS# 1219803-40-3) is a useful isotopically labeled research compound.

Applications Ethyl 2-Bromo-2-methyl-d3-propionate-3,3,3-d3 (CAS# 64768-38-3) is a useful isotopically labeled research compound.

Applications Tridecanoic-2,2-d2 Acid (CAS# 64118-44-1) is a useful isotopically labeled research compound.

Applications (±)-2-Chlorobutane-d9 (CAS# 175540-77-9) is a useful isotopically labeled research compound.

Applications 1,4-Di(methyl-d3)-naphthalene has been used in the preparation of di(trideuteriomethyl)naphthalene derivatives. 1,4-Di(methyl-d3)-naphthalene is a labeled analogue of 1,4-Dimethylnaphthalene (D476380), a polycyclic aromatic hydrocarbon (PAH) that has been found to retard the development of epidermoid carcinomas in hamster buccal pouch and alter the genes associated with the maintenance of a G1/S phase block possibly through the induction of the cell cycle inhibitors KRP1 and KRP2 in potatoes.
References Dizabo, P., et. al.: J. Labelled Compd., 2, 272 (1966); Malament, D.S., Shklar, G.: Carcinogenesis, 2, 723 (1981); Campbell, M.A., et. al.: Fuct. Interg. Genomics, 12, 533 (2012); Andrysik, Z., et. al.: Mutat. Res-Fund. Mol. M., 714, 53 (2011)

Applications Dicyclohexyl Carbonate-d22 is the isotope labelled analog of Dicyclohexyl Carbonate (D438505); a reagent in the synthesis of colon specific reduction sensitive polymers for pharmaceuticals.
References Schacht, E. and Wilding, I.: PCT Int. Appl. WO 9610994 A1 19960418. Apr 18, 1996

Applications Adenosine-2-d1 (CAS# 109923-50-4) is a useful isotopically labeled research compound.

Applications Tetracosanoic-12,12,13,13-d4 Acid (CAS# 1219794-59-8) is a useful isotopically labeled research compound.

Applications Iodoacetic Acid-d3 (CAS# 1219799-36-6) is a useful isotopically labeled research compound.

Applications Benzene-1,2,3,5-d4 (CAS# 14941-52-7) is a useful isotopically labeled research compound.

Applications Ammonium Formate-d5 (CAS# 65387-23-7) is a useful isotopically labeled research compound.

Applications Isotope labelled Propyl Paraben Sulfate (P838355) is the sulfate conjugate of Propyl Paraben (P838285), an antimicrobial agent used in cosmetic products.
References Kim, D.H., et al.: Biol. Pharma. Bull., 17, 1326 (1994);

Applications Phthalic-13C Acid is an isotope labelled version of Phthalic Acid (P384480), an organic reagent used to synthesize phthalates.
References Duchowicz, P.R., et al.: Bioorg. Med. Chem., 16, 7944 (2008);di Luccio, E., et al.: Biochem., 47, 4039 (2008);Lopez, Z., et al.: App. Microbiol. Biotechnol., 78, 739 (2008);Hong, Y., et al.: Toxicol. Lett., 184, 139 (2009)

Applications 2,3,6-Trimethylphenol-d11 (CAS# 347841-83-2) is a useful isotopically labeled research compound.

Applications 1-(3,5-Diacetoxyphenyl)-1-bromoethane-13C6, is the labeled analogue of 1-(3,5-Diacetoxyphenyl)-1-bromoethane (D307562), which is an intermediate for the synthesis of Resveratrol (R150000).
References Powell, R.G., et al.: Phytochemistry, 35, 335 (1994), Jeandet, P., et al.: J. Phytopathol., 143, 135 (1995), Mattivi, F., et al.: J. Agric. Food Chem., 43, 1820 (1995),

Applications 1-Bromo-3-chloro-5-fluorobenzene-d3 (CAS# 1219805-00-1) is a useful isotopically labeled research compound.

Applications 1,4-Diethylbenzene-d14 (CAS# 1219803-64-1) is a useful isotopically labeled research compound.

Applications n-Dodecyl Alcohol-d26 (CAS# 38086-03-2) is a useful isotopically labeled research compound. It can be used for neutron spin-echo spectroscopy.
References Yamaguchi, T., et.al., J. Phys.Chem.B., 123, 239-246,(2019);

Applications 5-(4-Hydroxyphenyl)-5-phenyl-d5-hydantoin-15N2 (CAS# 369656-71-3) is a useful isotopically labeled research compound.

Applications Propionic Acid (1-13c, 99%) (cas# 6212-69-7) is a useful research chemical.

Applications Ditridecyl Adipate-d8 is the isotope labelled analog of Ditridecyl Adipate (D494195); a compound used as a skin conditioning or fragrance ingredient, plasticizer, solvent or emollient in cosmetics. Also used in combination with other compounds as a finisher for texturing of polyester yarns.
References Fiume, M.M., et al.: Int. J. Toxicol., 31, 5S (2012); Burks, P.P., et al. Finish Composition for Draw-texturing Yarn. US 3859122 A 19750107. Jan 7, 1975

Applications O-Toluoyl Chloride-D7 is the deuterated form of O-Toluoyl Chloride (T536250), which is used in the synthesis if quinolinone compounds as SARS CoV 3CLpro inhibitors. Also used in the synthesis of benzooxaboroles as orally active anti-inflammatory agents.
References Sun, Y. et al.: Chin. J. CHem., 31, 1199 (2013); Akama, T. et al.: Bioorg. Med. Chem. Lett., 23, 5870 (2013);

Applications 1-Bromoeicosane-d41 (CAS# 202480-71-5) is a useful isotopically labeled research compound.

Applications Cyclopropane-1,2,2,3,3-d5-carbonyl chloride is a useful building block for organic synthesis

Applications Bis(3-methylpentyl) Phthalate-d4, is the labeled analogue of Bis(3-methylpentyl) Phthalate (B486010), used as a plasticizer to impart softness and flexibility to PVC products.
References Pierson, J. F., et al.: Angewandte Makromolekulare Chemie, 38, 167 (1979); Kaya, T., et al.: Chem. Res. Toxic., 19 (8), 999 (2006); Matter, H., et al.: Bioorg. Med. Chem., 20 (18), 5352 (2012);

Applications 2-Aminofluorene-d11 (CAS# 347841-44-5) is a useful isotopically labeled research compound.

Applications N2-Acetyl Acyclovir-d4 is the isotope labelled analog of N2-Acetyl Acyclovir (A168015); an impurity of Acyclovir (A192400) which is an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Also an antiviral.
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)

Applications 1-Bromodecane-d21 (CAS# 98195-39-2) is a useful isotopically labeled research compound.

Applications (±)-1-Phenylethan-1,2,2,2-d4-ol (CAS# 90162-44-0) is a useful isotopically labeled research compound.

Applications Diethyl L-(+)-Tartrate-13C8 is the isotope labelled analog of Diethyl L-(+)-Tartrate. Diethyl L-(+)-Tartrate is used as a chiral reagent in a host of chemical reactions, such as the synthesis of isoquinoline alkaloids and arundic acid, which has been used in acute ischemic stroke therapy.
References Ziolkowski, M. et al.: Tetrahedron Lett., 41, 1963 (2000); Fernandes, R. et al.: Tetrahedron Lett. 50, 5903 (2009);

Applications (S)-Carbidopa Methyl-d3 Ester N-cyclohexylidene is the labeled analogue of (S)-Carbidopa Methyl Ester N-cyclohexylidene (C176015), an impurity of Carbidopa (C175915), a prodrug inhibitor of aromatic amino acid decarboxylase.
References Sletzinger, M., et al.: J. Med. Chem., 6, 101 (1963)

Applications Compound has been shown to reversibly block voltage-dependent potassium channels, and is also a common impurity from the synthesis of compounds found in hair dyes
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Williams, D.M., et al.: J. Biol. Chem., 275, 38127 (2000), Munoz-Caro, C., et al.: Biophys. Chem., 96, 1 (2002),

Applications 1,3-Diethylbenzene-2,4,5,6-d4 (CAS# 1219803-29-8) is a useful isotopically labeled research compound.

Applications Ethyl 2,3-Dicyanopropionate-13C2 15N2, is the labeled analogue of Ethyl 2,3-Dicyanopropionate (E915950), which is an intermediate for insecticide.
References Cole, L., et al.: Pestic. Biochem. Physiol., 46, 47 (1993), Cole, L., et al.: Life Sci., 56, 757 (1995), Hosie, A., et al.: Br. J. Pharmacol., 115, 909 (1995),

Stability Light Sensitive
Applications Isotope Labelled Ethaboxam is a pesticide used as a fungicide against fungal infections in crops.
References Kim, D. et al.: Pest Manage. Sci., 60, 1007 (2004); Park, M. et al.: J. Microbiol. Biotech., 13, 43 (2003);

Applications 4-Bromo-2-(ethyl-d3)pyridine is an intermediate in the synthesis of Ethionamide-d3 (E890422), a labelled antibacterial (tuberculostatic) agent.
References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),

Applications Isotope labelled 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol, the novel raw material for deodorants application and is widely used as a cosmetic emollient. 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol reliably inhibits the odor-causing bacteria, yeast and fungi on the skin.
References Nagao, S.: Frag. J., 34, 39 (2006); Lawan, K. et al.: J. Health Sci., 23, 1 (2009); Leschke, M.: SOFW J., 136, 10 (2010);

Applications N-Suberylglycine-2,2-d2 (CAS# 1219799-02-6) is a useful isotopically labeled research compound.

Applications 2,4,6-Trimethylbenzeneamine-d11 (cas# 1126138-13-3) is a compound useful in organic synthesis.

Applications 4-Fluorobenzyl-d6 Alcohol (CAS# 1071809-48-7) is a useful isotopically labeled research compound.

Applications Labelled Cortisol-d4 21-Sulfate (C696320). Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).
References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),

Applications 4-Fluorobenzyl-2,3,5,6-d4-amine (CAS# 1219798-96-5) is a useful isotopically labeled research compound.

Applications 1-Iodopropane-1,1-d2 (CAS# 25493-14-5) is a useful isotopically labeled research compound.

Applications Cyclopropane-d5-carboxylic Acid (CAS# 1219804-09-7) is a useful isotopically labeled research compound.

Applications Acetamide-d5 (CAS# 33675-83-1) is a useful isotopically labeled research compound.

Applications 3-(Cyclohexylamino)-1-propanesulfonic-d17 Acid (CAS# 1219804-15-5) is a useful isotopically labeled research compound.

Applications 1-Bromooctane-3,3,4,4-d4 (CAS# 1219803-37-8) is a useful isotopically labeled research compound.

Applications 1-[5-Chloro-2-(2,4-dichlorophenoxy)phenylethanone]-d2 Major (cas# 1189477-14-2) is a compound useful in organic synthesis.

Applications Styrene-alpha,beta,beta-d3 (CAS# 3814-93-5) is a useful isotopically labeled research compound.

Applications Ethylene Glycol Monooctanoate-d4 is a deuterated version of Ethylene Glycol Monooctanoate (E917547), a reactant in the synthesis of water-woluble phospholipid analogues as inhibitors of phospholipase C.
References Franklin, Christopher L., et al.: J. of Org. Chem., 68(19), 7298-7307 (2003)

Applications Ethylbenzene-2,3,4,5,6-d5 (CAS# 20302-26-5) is a useful isotopically labeled research compound.

Applications (±)-2-Chloropropionyl-2,3,3,3-d4 Chloride (CAS# 1219794-98-5) is a useful isotopically labeled research compound.

Applications 1,4-Cyclohexane-d10-diamine (cis/trans mixture) (CAS# 1219802-80-8) is a useful isotopically labeled research compound.

Applications An intermediate for the synthesis of Labelled Ketoprofen.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Derewenda, Z., et al.: J. Mol. Biol., 227, 818 (1992), Grochulski, P., et al.: J. Biol. Chem., 268, 12843 (1993).

Applications N-(2-(1,3-Dioxoisoindolin-2-yl)ethoxy-d4)benzamide is an intermediate in the synthesis of Fluvoxamine-d4 Maleate (F603503), a selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant. Antiobsessional.
References Claassen, V., et al.: Br. J. Pharmacol., 60, 505 (1977); Koran, L.M., et al.: J. Clin. Psychopharmacol., 16, 121 (1996); Ware, M.R., et al.: J. Clin. Psychiatry, 58, Suppl. 5, 15 (1997); Inazu, M., et al.: Neurochem. Int., 39, 39 (2001)

Applications Dodecylphosphocholine (D38, 98%) (cas# 130890-78-7) is a useful research chemical.

Applications (3,4,5-Trimethoxyphenyl)acetic-alpha,alpha-d2 Acid (CAS# 344299-45-2) is a useful isotopically labeled research compound.

Applications Potassium Dodecanoate-d23 (CAS# 51732-20-8) is a useful isotopically labeled research compound.

Applications 4-n-Octyl-d17-anisole (CAS# 1219794-56-5) is a useful isotopically labeled research compound.

Applications Isotope labelled Glycerol (G598400) is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.
References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976),

Applications 4-Fluoro-1,3-dioxolan-2-one-d3 is the labeled version of 4-Fluoro-1,3-dioxolan-2-one (F591523)

Applications (2,4-Dichlorophenoxy-d3)acetic-d2 Acid (CAS# 352438-69-8) is a useful isotopically labeled research compound.

Applications N-Methylform-d1-amide (CAS# 26103-38-8) is a useful isotopically labeled research compound.

Applications Tetradecanoic-14,14,14-d3 Acid (CAS# 62217-71-4) is a useful isotopically labeled research compound.

Applications Reagent used in the addition of labelled cyclopropane.

Applications Sodium 2-Methylpropionate-1-13C (CAS# 71105-51-6) is a useful isotopically labeled research compound.

Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide-d4 is the isotope labelle danalog of N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide. N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).
References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)

Stability Hygroscopic
Applications Phenylboronic Acid-d5 is the isotope labelled analog of Phenylboronic Acid (P319590); a compound used in the organic synthesis of various pharmaceutical goods.
References Ainley, A.D., et al.: J. Chem. Soc., 2171 (1930)

Applications 2-Mercaptoethanol-1,1,2,2-d4 (CAS# 284474-53-9) is a useful isotopically labeled research compound.