Organic Halides

Applications 3,6-Dibromo-9H-fluoren-9-one is a reagent in the preparation of diphenylamine-fluorenone derivatives as potential fluorescent probes for neuroblastoma cell staining.
References Capodilupo, A., et al.: Tetrahedron, 72, 2920 (2016)

Applications 2-Chloroethyl Formate is a chemical reagent used in the hydrolysis of esters.
References Stefanidis, D. et al.: J. Am. Chem. Soc., 115, 6045 (1993);

Applications 4-Fluoro-2-iodoaniline is a useful reactant for the synthesis of cyclohepta[b]indole scaffold via annulative two-carbon ring-expansion.
References Tymann, D. C., et al.: Chem. Eur. J, 26, 11974 (2020)

Stability Hygroscopic
Applications 2-Chloroethyl benzoate (cas# 939-55-9) is a useful research chemical.

Applications 3-Bromomethylphenylboronic acid, pinacol ester

Applications 4-Bromo-2-(trifluoromethyl)benzoic acid

Applications (4S-trans)-4-(Methoxymethyl)-2,2-dimethyl-5-(trifluoromethyl)-1,3-dioxane is a organic reagent and building block in pharmaceutical synthesis.
References Di Francesco, M. PCT Int. Appl. (2016), WO 2016004417 A1 20160107.

Applications ethyl 4-aminopentanoate hydrochloride (cas# 119396-97-3) is a useful research chemical.

Applications Ethenesulfonyl chloride is a useful reactant for the preparation of oral quinoline-based ALDH1A1 inhibitors as potential antitumor agents.
References Yang, SM., et al.: J. Med. Chem., 61, 4883-4903 (2018);

Applications 1-Chloro-3-(3,5-dimethylphenoxy)-2-propanol is an intermediate used in the synthesis of 1-Amino-3-(3,5-dimethylphenoxy)-2-propanol (A607300), which is a degradation product of Metaxalone (M225850); a muscle relaxant used to relax muscles and relieve pain.
References Rao, R.N., et al.: Biomed. Chromatogr., 27, 1733 (2013)

Applications Cyclopropylhydrazine Dihydrochloride, is a building block used in preparation of more complex compound.

Applications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000).
References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);

Applications 2-Bromo-1,4-dichlorobenzene is a reactant used in the synthesis of C-13 and C-14-labeled versions of the investigational proteasome inhibitor MLN9708.
References Plesescu, M., et. al.: J. Labelled Compd. Rad., 56, 464 (2013)

Dichlorodiisopropylsilane is a cycloaddition process, which is the addition of two molecules to create a new ring. It reacts with an unsaturated organic compound, such as an alkene or alkyne, to produce a reactive functional group. Dichlorodiisopropylsilane has been used in chemistry as a cross-linking agent for proteins and as a solid catalyst. The chemical stability of dichlorodiisopropylsilane makes it useful in the synthesis of model proteins. This compound also has low bioavailability due to its high reactivity with hydrochloric acid found in the stomach.

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Didecyl dimethyl ammonium chloride is a quaternary ammonium compound that has been shown to have a broad-spectrum antimicrobial activity. It has been used in disinfectants and as an active ingredient in pharmaceuticals, cosmetics, and foods. The compound is not toxic to humans or animals at concentrations up to 50%. Didecyl dimethyl ammonium chloride has been shown to be effective against infectious diseases caused by bacteria, viruses, fungi, and protozoa. This compound also has an effect on the epithelial-mesenchymal transition (EMT) process. Didecyl dimethyl ammonium chloride can be prepared by titration calorimetry or analytical method. The preparation of didecyl dimethyl ammonium chloride can be done using chloroform and benzalkonium chloride or glycol ether.

2-(4-Chlorophenyl)ethylamine (CPA) is a synthetic serotonergic amine that has inhibitory activities. It is able to bind with the 5-HT receptor, which is also known as the serotonin receptor. CPA has been shown to be an anticancer compound and can be used in experimental solubility studies. This drug binds to brain cells, but does not affect their viability. CPA hydrolyzes in the presence of hydrochloric acid or hydrogen chloride to produce 2-(4-chlorophenyl)ethanol (CPE). The reaction of CPA with serotonin produces 4-chloroamphetamine (PCA), which is a stimulant drug.

Please enquire for more information about 4-Chloro-3,5-difluorobenzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,6-Dibromoanthracene is an aromatic hydrocarbon that can be synthesized in a cross-coupling reaction. It has been shown to have a high electron mobility and good thermal stability. The compound was prepared by the Suzuki coupling reaction of 2,6-dibromobenzene with phenylboronic acid. This product has no commercial use but has been tested for its transport properties and has been found to be activated by heat.

Cyclopropanesulfonyl chloride (CPSC) is a bicyclic heterocycle that has been shown to have potent inhibitory activity against the human pathogens hepatitis B virus, dengue virus, and influenza A virus. CPSC inhibits the NS3 protease of these viruses by forming hydrogen bonding interactions with the nucleophilic nitrogen atom of the enzyme and also by competing with a chloride ion for binding to the chlorine atom on the enzyme. It also inhibits HIV-1 infection in cell culture experiments. CPSC has been found to be effective in preventing inflammation caused by cytokines, such as interleukin-1β, tumor necrosis factor-α, and prostaglandin E2. The inhibition of inflammatory cytokines may be due to its ability to bind glucocorticoid receptors.