
Toxicology
Found 13573 products of "Toxicology"
Isometheptene Maleate
CAS:Applications Isometheptene Maleate belongs to a group of sympathomimetic amine and shows very little antihypertensive activity. Isometheptene Maleate is used as an antispasmodic drug.
References Vidrio, H. et al.: J. Pharmacol. Exp. Therap., 187, 308 (1973); Taylor, W.G. et al.: Drug Metab. Disp., 5, 564 (1977);Formula:C9H19N·C4H4O4Color and Shape:White To Off-WhiteMolecular weight:257.33Atropine Sulfate Monohydrate
CAS:Controlled ProductApplications Mydriatic; antispasmodic; used in preanesthetic medication.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brown, R.V., et al.: Br. J. Pharmacol., 15, 170 (1960), Shutt, L.E., et al.: Anaesthesia, 34, 476 (1979), Hinderling, P.H., et al.: J. Pharm. Sci., 74, 703 (1985),Formula:C17H23NO3·H2O4S·H2OColor and Shape:White To Light YellowMolecular weight:694.83Hydrocortisone 17-Butyrate 21-Propionate
CAS:Controlled ProductApplications A synthetic adrenocorticosteroid that acts as an anti-inflammatory and anti-pruritic agents. It is used as a topical for the treatment of dermatologic disorders such as atopic dermatitis and psoriasis.
References Mason, J. et al.: Br. J. Dermatol., 146, 351 (2002); Sears, H.W. et al.: Clin. Therap., 19, 710 (1997); Otomo, Y.Z. et al.: Nip. Yakur. Zas., 78, 647 (1981);Formula:C28H40O7Color and Shape:White To Off-WhiteMolecular weight:488.61Hydroxy Dehydro Nifedipine Lactone
CAS:Controlled ProductFormula:C16H12N2O6Color and Shape:NeatMolecular weight:328.28Nicergoline-d3
CAS:Controlled ProductApplications Nicergoline-d3 is the labeled analogue of Nicergoline(N394550), a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia.
References Caraci, F., et. al.: Brain Res., 1047, 30 (2005); Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)Formula:C24D3H23BrN3O3Color and Shape:NeatMolecular weight:487.404N-Desmethyl Clomipramine Hydrochloride
CAS:Controlled ProductApplications A metabolite of Clomipramine.
References McTavish, D., et al.: Drugs, 39, 136 (1990), Chauret, N., et al.: Drug Metab. Dispos., 25, 1130 (1997), Gex-Fabry, M., et al.: Ther. Drug Monit., 22, 701 (2000), Herrera, D., et al.: J. Clin. Pharmacol., 40, 1488 (2000),Formula:C18H21ClN2·ClHColor and Shape:Off-WhiteMolecular weight:337.296α-Hydroxy Progesterone (>80%)
CAS:Controlled ProductFormula:C21H30O3Purity:>80%Color and Shape:NeatMolecular weight:330.461,2-Dihydro Beclomethasone Dipropionate
CAS:Controlled ProductImpurity Beclomethasone Dipropionate EP Impurity L
Applications 1,2-Dihydro Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity L) is an impurity of Beclomethasone Dipropionate (B131030).Formula:C28H39ClO7Color and Shape:NeatMolecular weight:523.063-Dehydro Retinal
CAS:Controlled ProductStability Light Sensitive, Temperature Sensitive
Applications An oxidized derivative of the visual pigment carotenoid.
References Wada, A., et al.: Chem. Pharm. Bull., 56, 112 (2008), Smolensky, E., et al.: Biochem., 48, 9170 (2009),Formula:C20H26OColor and Shape:NeatMolecular weight:282.423-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt
CAS:Controlled ProductApplications 3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt is deuterium labeled 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt (C994750), which is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).Minimum isotopic incorporation d-3, no d-0 present. A representative lot has 64% isotopic incorporation at the 6-position, 89% at the 4-position.
References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)Formula:C11H9D5N2O4S•C2HF3O2Color and Shape:NeatMolecular weight:389.36Campesteryl Ferulate
CAS:Controlled ProductApplications Campesteryl Ferulate is a component of γ-oryzanol with antioxidant activities.
References Xu, Z., et al.: J. Agric. Food Chem., 49, 2077 (2001);Formula:C38H56O4Color and Shape:NeatMolecular weight:576.8521-Carboxylic Acid Triamcinolone Acetonide
CAS:Applications A metabolite of Triamcinolone acetonide.
References Edsbacker, S., et al.: Drug Metab. Dispos., 11, 590 (1983), Szefler, S., et al.: Eur. J. Clin. Pharmacol., 30, 323 (1986), Hansel, T., et al.: J. Immunol. Methods, 145, 105 (1991), Argenti, D., et al.: J. Clin. Pharmacol., 39, 695 (1999),Formula:C24H29FO7Color and Shape:NeatMolecular weight:448.484’-Hydroxyphenprocoumon
CAS:Controlled ProductApplications 4’-Hydroxyphenprocoumon is a metabolite of the oral anticoagulant Phenprocoumon (P318820).
References De Vries, J. et al.: J. Chrom. Biomed. Appl., 529, 479 (1990);Formula:C18H16O4Color and Shape:NeatMolecular weight:296.3216-Oxo Ethynyl Estradiol
CAS:Controlled ProductImpurity Ethinylestradiol EP Impurity H
Applications A degradation product of Ethynyl Estradiol (EE), (E685100).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormula:C20H22O3Color and Shape:Off-WhiteMolecular weight:310.394-Hydroxy Propofol Sulfate Sodium Salt
CAS:Applications 4-Hydroxy Propofol sulfate sodium salt is a derivative of Propofol, a hypnotic intravenous agent that is commonly used as an anasthetic for conscious sedation.
References GüLCIN, I., et al.: Chem. Pharm. Bull., 53, 281 (2005); Koshy, G., et al.: Am. J. Gastroenterol., 95, 1476 (2000)Formula:C12H17NaO5SColor and Shape:NeatMolecular weight:296.324-Methoxy Retinoic Acid
CAS:Controlled ProductApplications: An impurity contained in samples of all trans-retinoic acid.
References Newton, D., et al.: Cancer Res., 40, 3413 (1980), Curley, R., et al.: Bioorg. Med. Chem. Lett., 2, 1133 (1992), Tanaka, H., et al.: Chem. Pharm. Bull., 43, 356 (1995), Patel, J., et al.: J. Med. Chem., 47, 6716 (2004),Formula:C21H30O3Color and Shape:Off White SolidMolecular weight:330.46O-Methyl Atorvastatin Calcium Salt
CAS:Controlled ProductImpurity Atorvastatin EP Impurity G
Applications Atorvastatin derivative.Formula:C34H36FN2O5·CaColor and Shape:Off-WhiteMolecular weight:1183.39Rosuvastatin tert-Butyl Ester
CAS:Controlled ProductStability Hygroscopic
Applications Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.
References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),Formula:C26H36FN3O6SColor and Shape:NeatMolecular weight:537.646,7,8,9-Tetrahydro Carvedilol
CAS:Controlled ProductApplications Carvedilol (C184625) derivative.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormula:C24H30N2O4Color and Shape:NeatMolecular weight:410.512-(1-Hydroxyethyl) Promazine
CAS:Applications A metabolite of Acepromazine (A130900).
References Cossum, P., et al.: Drug Dispos., 9, 321 (1988), Stowell, L., et al.: J. Anal. Toxicol., 22, 166 (1998),Formula:C19H24N2OSColor and Shape:NeatMolecular weight:328.47Imipenem, Monohydrate
CAS:Controlled ProductFormula:C12H17N3O4S·H2OColor and Shape:White To Light YellowMolecular weight:317.367α-Thiomethyl Spironolactone-d7 (Major)
CAS:Controlled ProductApplications A labelled metabolite of Spironolactone.
References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),Formula:C23H25D7O3SColor and Shape:NeatMolecular weight:395.61Desacetyl Diltiazem
CAS:Impurity Diltiazem EP Impurity F
Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).
References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),Formula:C20H24N2O3SColor and Shape:White To BrownMolecular weight:372.48Petromyzonol 24-Sulfate Sodium Salt
CAS:Controlled ProductFormula:C24H41O7S·NaColor and Shape:NeatMolecular weight:496.635-Hydroxy Albuterol Hemisulfate Salt
CAS:Controlled ProductApplications The 5-hydroxy analogue of the bronchodilator, Albuterol (A514500).
Formula:C13H21NO4H2SO4Color and Shape:NeatMolecular weight:304.35Tenivastatin Calcium Hydrate
CAS:Controlled ProductApplications Tenivastatin Calcium is derived from Simvastatin (S485000), which is a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986)Formula:C25H39O6Ca·xH2OColor and Shape:NeatMolecular weight:965.3Quinidine-d3
CAS:Controlled ProductApplications A dextrorotatory stereoizomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 483 (1983), Mason, J. W., et al.: Ann. N. Y. Acad. Sci., 432, 162 (1984),Formula:C202H3H21N2O2Color and Shape:Off-WhiteMolecular weight:327.442,3-Pyridinedicarboxylic Acid-d3 (Major)
CAS:Controlled ProductApplications A labelled inhibitor of glucose synthesis.
References Garcia-Salguero, L. et al.: Arch. Int. Physiol., Biochim. Biophys., 99, 237, (1991); Martirosyan, A., et al.: Biochem. Pharmacol., 68, 1729 (2004);Formula:C7D3H2NO4Color and Shape:NeatMolecular weight:170.14b-Cembrenediol
CAS:Controlled ProductStability Light Sensitive
Applications β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments.
References Le-Huu, P. et al.: ChemCatChem., 8, 3755 (2016); Ebrahim, H. et al.: Bioorg. Med. Chem., 24, 5748 (2016);Formula:C20H34O2Color and Shape:Off-WhiteMolecular weight:306.48(S)-Viloxazine Hydrochloride
CAS:Controlled ProductApplications The (S)-isomer of Viloxazine (V312440). Antidepressant.
References Howe, R., et al.: J. Med. Chem., 19, 1074 (1976), Pinder, R.M., et al.: Drugs, 13, 401 (1977),Formula:C13H20ClNO3Color and Shape:NeatMolecular weight:273.76Pipamazine
CAS:Applications Pipamazine is a drug od the phenothiazine class which used to be used as an antiemetic.
References Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 22, 154 (1964); Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 21, 436 (1963);Formula:C21H24ClN3OSColor and Shape:NeatMolecular weight:401.95Diphenhydramine N-Oxide
CAS:Stability Hygroscopic
Applications A metabolite of Diphenhydramine (D486900) in humans.
References Breyer-Pfaff, U., et al.: Drug Metab. Dispos., 25, 340 (1997),Formula:C17H21NO2Color and Shape:NeatMolecular weight:271.35Celecoxib Carboxylic Acid
CAS:Controlled ProductFormula:C17H12F3N3O4SColor and Shape:Off WhiteMolecular weight:411.3617β-Dihydro Equilin 3-Sulfate Sodium Salt
CAS:Stability Hygroscopic
Applications A metabolite of Equilin (E592800).
References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),Formula:C18H21O5S·NaColor and Shape:NeatMolecular weight:372.41α-Propyl-α-(1-demethylethyl)-Verapamil Hydrochloride
CAS:Controlled ProductApplications α-Propyl-α-(1-demethylethyl)-Verapamil is an impurity of Verapamil (V125000, HCl salt) which is a calcium channel blocker.
References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)Formula:C27H38N2O4·ClHColor and Shape:NeatMolecular weight:491.06Chloro Chlorthalidone
CAS:Controlled ProductFormula:C14H9Cl2NO2Color and Shape:NeatMolecular weight:294.134-Hydroxy Atorvastatin Hemicalcium Salt
CAS:Applications 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);Formula:C66H68CaF2N4O12Purity:>90%Color and Shape:NeatMolecular weight:1187.34cis-10-Hydroxy Nortriptyline
CAS:Applications A metabolite of Nortriptyline (N837000).
References Callaghan, R., et al.: J. Biol. Chem., 268, 16059 (1993), Dagenais, C., et al.: Biochem. Pharmacol., 67, 269 (2004), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),Formula:C19H21NOColor and Shape:NeatMolecular weight:279.38Hederagenin
CAS:Applications Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.
References Cho, J., et al.: Pulmon. Pharmacol. Ther., 23, 190 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Saha, S., et al.: J. Agric. Food Chem., 58, 434 (2010),Formula:C30H48O4Color and Shape:NeatMolecular weight:472.7Azidoethanol
CAS:Controlled ProductApplications 2-Azidoethanol is used as a reagent in the glycosylation of mono- or polysaccharides. 2-Azidoethanol is also used as a 2’-deoxy-ethynyluridine (EdU) blocker in nuclear DNA, preventing cross reactivity with other antibodies in order to better study its related pathways in the body.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Liboska, R., et al.: PLOS ONE, 7, e51679 (2012); Sun, X., et al.: Biomacromolecules, 3, 1065 (2002)Formula:C2H5N3OColor and Shape:ColourlessMolecular weight:87.08Ezetimibe Tetrahydropyran Impurity
CAS:Impurity Ezetimibe Tetrahydropyran Impurity
Applications Ezetimibe (E975000) tetrahydropyran impurity.Formula:C24H21F2NO3Color and Shape:NeatMolecular weight:409.431,2-Dihydro Desoxymetasone
CAS:Controlled ProductApplications A metabolite of Desoxymetasone (D296970).
References Schriks, M., et al.: Environ. Sci. Technol., 44, 4766 (2010), Baeck, M., et al.: Eur. J. Dermatol., 20, 102 (2010), Lee, P., et al.: Bioorg. Med. Chem. Lett., 20, 69 (2010),Formula:C22H31FO4Color and Shape:NeatMolecular weight:378.485-Oxo Atorvastatin
CAS:Applications Atorvastatin Derivative
Formula:C33H33FN2O5Color and Shape:NeatMolecular weight:556.62Atorvastatin Lactam Sodium Salt Impurity
CAS:Impurity Atorvastatin Pyrrolidone Analog (USP)
Stability Light Sensitive
Applications A photodegradation product of Atorvastatin (a cyclic impurity of Atorvastatin). Atorvastatin Pyrrolidone Analog (USP).
References Roger, D., et al.: Clin. Exp. Dermatol., 19, 88 (1994), Cosa, G., et al.: Photochem. Photobiol., 80, 159 (2004), Kerwin, B., et al.: J. Pharm. Sci., 96, 1468 (2007),Formula:C33H34FN2O6·NaColor and Shape:WhiteMolecular weight:596.629-Deschloro-9-bromo Beclomethasone Dipropionate
CAS:Controlled ProductImpurity Beclomethasone Dipropionate EP Impurity D
Applications 9-Deschloro-9-bromo Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity D) is an impurity of Beclomethasone Dipropionate (B131030).
References Shou, M. et al.: J. Pharmac. Biomed. Anal., 50, 356 (2009); Johnston, S. et al.: J. Chrom. Sci., 48, 733 (2010);Formula:C28H37BrO7Color and Shape:NeatMolecular weight:565.49Daidzein 7-β-D-Glucuronide 4’-Sulfate Disodium Salt
CAS:Stability Very Hygroscopic
Applications Mixed conjugate of dietary phytoestrogen.
References Adlercreutz, H;., et al.: J. Steroid Mol. Biol., 52, 97 (1995), Kinjo, J., et al.: Biol. Pharm. Bull., 27, 185 (2004),Formula:C21H16Na2O13SColor and Shape:NeatMolecular weight:554.39Carbimazole
CAS:Applications Carbimazole, a prodrug of Methimazole (M260300), is used in the treatment of hyperthyroidism.
References Marchant, B., et al.: J. Clin. Endocrinol. Metab., 45, 1187 (1977), Johnsson, E., et al.: Lancet, 350, 1520 (1997),Formula:C7H10N2O2SColor and Shape:NeatMolecular weight:186.23Higenamine Hydrobromide Salt
CAS:Controlled ProductApplications Higenamine acts through inhibition of middle cerebral artery occlusion (MCAO)-mediated HMGB1 release in vivo. Useful towards ischemic injuries.
References Ha, Y. et al.: Apoptosis., 17, 463 (2012);Formula:C16H18BrNO3Color and Shape:Off-WhiteMolecular weight:352.223-Methyloxazinane Arbidol
CAS:Controlled ProductFormula:C22H24BrN2O3SColor and Shape:NeatMolecular weight:476.407Methaqualone
CAS:Controlled ProductFormula:C16H14N2OColor and Shape:White To Off-WhiteMolecular weight:250.3Testosterone Cypionate
CAS:Controlled ProductApplications Testosterone Cypionate is an anabolic steroid with androgenic properties. Testosterone Cypionate is used for testosterone therapy in males with hypogonadism.Controlled Substance.
References Rabkin, J. G., et al.: J. Clin. Psychopharmacol., 19, 19 (1999); Hajjar, R., et al.: J. Clin. Endocrinol. Metab., 82, 3793 (1997); Rhoden, E., et al.: J. Sex Med., 7, 277 (2010);Formula:C27H40O3Color and Shape:NeatMolecular weight:412.6DL-Erythro Ritalinic Acid
CAS:Controlled ProductApplications A major metabolite of Methylphenidate.
References Redalieu, E., et al.: Drug Metab. Dispos., 10, 708 (1982), Brewer, E., et al.: J. Pharm. Sci., 87, 395 (1998), Shah, V., et al.: Pharm. Res., 17, 1551 (2000), Tanaka, N., et al.: Anal. Chem., 73, 420 (2001),Formula:C13H17NO2Color and Shape:WhiteMolecular weight:219.283-Hydroxy Tibolone-d5 (mixture of 3Alpha & 3Beta isomers)
CAS:Controlled ProductApplications 3-Hydroxy Tibolone-d5, is the labeled analogue of 3-Hydroxy Tibolone, a synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Belman, S., et al.: Cancer Res., 32, 450 (1972), Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1993), Hoyte, R., et al.: Steroids, 58, 13 (1993), Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (2005),Formula:C21H25D5O2Color and Shape:NeatMolecular weight:319.49Ramipril-d3
CAS:Controlled ProductApplications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite.
References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),Formula:C23H29D3N2O5Color and Shape:NeatMolecular weight:416.51rac-erythro Methylphenidate Hydrochloride
CAS:Controlled ProductApplications The erythro isomers have been shown to exhibit very little therapeutic effect and contribute mainly to the toxic hypertensive effects of this drug.Controlled substance.
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., et al.: Anal. Profiles Drug Subs., 10, 473 (1981), Kuczenski, R., et al.: J. Pharmacol. Exp. Ther., 296, 876 (2001), Pelham, W.E., et al.: J. Consult. Clin. Psychol., 61, 506 (1993), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),Formula:C14H19NO2·ClHColor and Shape:NeatMolecular weight:269.77N-Hydroxy Norfloxacin
CAS:Applications A metabolite of Norfloxacin (N681000).
References Uno, T., et al.: J. Med. Chem., 33, 2929 (1990),Formula:C16H18FN3O4Color and Shape:NeatMolecular weight:335.33Cyclosporin A-13C2,d4 Acetate
CAS:Controlled ProductApplications Labelled Cyclosporin A (C988901) derivative. An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005)Formula:C62C2H109D4N11O13Color and Shape:NeatMolecular weight:1250.657-Keto Dehydro Epiandrosterone
CAS:Controlled ProductApplications 7-Keto Dehydro Epiandrosterone is a metabolite of Dehydroepiandrosterone (DHEA) (D229585).
References Majewska, M., et al.: Brain Res., 526, 143 (1990), Charlton, M., et al.: J. Neurochem., 68, 121 (1997), Koob, G., et al.: Biochem. Pharmacol., 68, 1515 (2004);Formula:C19H26O3Color and Shape:WhiteMolecular weight:302.41Aldicarb-d3
CAS:Controlled ProductApplications Labelled Aldicarb (A514650). Aldicar is used as an insecticide. Used in Pesticide detection.
References Ashby, J., et al.: Environ. Mutagen., 7, 919 (1985), Ashby, J., et al.: Mutat. Res., 257, 229 (1991), Kazius, J., et al.: J. Med. Chem., 48, 312 (2005), Benigni, R., et al.: Mutagenesis, 25, 335 (2010),Formula:C7H14N2O2SColor and Shape:White To Off-WhiteMolecular weight:193.28Meprobamate-d3 (methyl-d3)
CAS:Controlled ProductApplications A deuterated version of Meprobamate, an anxiolytic.This is a controlled substance. Liscence required.
References Summerfield, S., et al.: J. Pharmacol. Exp. Ther., 322, 205 (2007), Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008), Cone, E., et al.: J. Anal. Toxicol., 33, 1 (2009),Formula:C92H3H15N2O4Color and Shape:Off White SolidMolecular weight:221.27Metolachlor-d6
CAS:Controlled ProductApplications Isotope labelled Metolachlor (M338702), which is an acyanilide herbicide similar to selective pre-emergence herbicides (1). It is a contaminant in the groundwater and potential pollutant (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. McGahen, L. et al.: J. Agric. Food Chem. 1978 26 (2), pp 414–4192. Chesters, G. et al.: Rev. Environ Contam Toxicol. 1989;110:1-74.Formula:C152H6H16ClNO2Color and Shape:Light Yellow To Light BrownMolecular weight:289.83Norepinephrine Sulfonic Acid
CAS:Applications Norepinephrine Sulfonic Acid is a derivative of DL-Norepinephrine Hydrochloride (N674500), antagonist of dibutyryl cyclic-AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Piguet, P., et al.: J. Exp. Med., 173, 673 (1991), Hosoi, J., et al.: Nature, 363, 159 (1993), Elenkov, I., et al.: Pharmacol. Rev., 52, 595 (2000), Kaplan, D., et al.: Immunity, 23, 611 (2005),Formula:C8H11NO5SColor and Shape:Red To GreyMolecular weight:233.243-Methyl-4-nitroimino-tetrahydro-1,3,5-oxadiazine
CAS:Stability Light Sensitive
Applications 3-Methyl-4-nitroimino-tetrahydro-1,3,5-oxadiazine is a useful synthetic intermediate in the synthesis of Thiamethoxam (T344180); a neonicotinoid insecticide.
References Maienfisch, P., et al.: Z. Naturforsch. B., 61, 353 (2006); Fan, W., et al.: Shanghai Huagong, 27, 25 (2002); Maienfisch, P., et al.: Chimia, 57, 710 (2003); Oliver, J., et al.: J. Environ. Horticult., 28, 135 (2010); Ghosh, A., et al.: J. Entomol. Res., 34, 35 (2010)Formula:C4H8N4O3Color and Shape:NeatMolecular weight:160.13Iprovalicarb-d8
CAS:Controlled ProductApplications Iprovalicarb-d8 is the deuterated form of Iprovalicarb (I747500), which is a systematic fungicide. Iprovalicarb is used for the control of pathogenic fungi from the oomycetes class in grapes, potatoes, tomatoes and other crops.
References Stubler, D., et al.: Pflanzensch.-Nach. Bay., 52, 33 (1999); Stenzel, K., et al.: Bright. Crop Prot. Conf. Pests Dis., 2, 367 (1998);Formula:C18D8H20N2O3Color and Shape:Off-WhiteMolecular weight:328.47583-Hydroxy-5-phenylpyrrole
CAS:Stability Air Sensitive
Applications Used for detecting the presence of hydrolytic analytes, such as leukocytes, esterase, and protease. The detection of leukocytes is especially important in medical diagnostics.
References Jackson, D.S., et al.: Arch. Biochem. Biophys., 20, 323(1), 108 (1995)Formula:C10H9NOColor and Shape:NeatMolecular weight:159.18(S)-Linagliptin
CAS:Applications (S)-Linagliptin is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);Formula:C25H28N8O2Color and Shape:NeatMolecular weight:472.54Tetrahydrodehydrocorticosterone
CAS:Controlled ProductApplications Tetrahydrodehydrocorticosterone inhibits aldosteronogenesis by intact cells at concentrations that inhibited angiotensin binding.
References Campanile, C.P., Goodfriend, T.L.: Steroids, 37, 681(1981)Formula:C21H32O4Color and Shape:NeatMolecular weight:348.48Faradiol 3-Laurate
CAS:Controlled ProductFormula:C42H72O3Color and Shape:NeatMolecular weight:625.019Phenobarbital-d5 (ethyl-d5)
CAS:Controlled ProductApplications This is a controlled substance (depressant). Anticonvulsant; sedative; hypnotic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Chao, M.K.C., et al.: Anal. Profiles Drug Subs., 7, 359 (1978),Formula:C122H5H7N2O3Color and Shape:WhiteMolecular weight:237.27(S)-(+)-N-3-Benzylnirvanol
CAS:Controlled ProductApplications It is a potent and selective human CYP2C19 inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Suzuki, H., et al.: Drug Metab. Dispos., 30, 235 (2002), Robert, L., et al.: Drug Metab. Dispos., 31, 343 (2003),Formula:C18H18N2O2Color and Shape:White To Off-WhiteMolecular weight:294.35Clothianidin-d3 (N-methyl-d3)
CAS:Controlled ProductApplications Clothianidin-d3 (N-methyl-d3) (CAS# 1262776-24-8) is a useful isotopically labeled research compound. This compound can be used to detect trace levels of neonicotinoid insecticides in honey bee royal jelly using ultra-sound assisted liquid-liquid extraction-UHPLC/MS.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Giroud, B., et.al., Microchemical J., 151,104249,(2019);Formula:C62H3H5ClN5O2SColor and Shape:NeatMolecular weight:252.7Bortezomib-D8 (Major)
CAS:Controlled ProductApplications Labelled Bortezomib, which the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells.d6-3%d7-10%d8-86%
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005)Formula:C19H17D8BN4O4Color and Shape:Off-WhiteMolecular weight:392.291,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide-d3
CAS:Controlled ProductApplications 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide-d3 is the isotope labelled analog of 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide (D453415); a compound that has been shown to be one of the potential novel biomarkers of peroxisome proliferation in the rat.
References Ringeissen, S., Biomarkers, 8, 240 (2003); Shibata, K., et al.: Biosci. Biotech. and Biochem., 77, 2105 (2013)Formula:C72H3H5N2O2Color and Shape:White To Off-WhiteMolecular weight:155.17Anastrozole Acid Amide
Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.
References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)Formula:C17H22N4O3Color and Shape:NeatMolecular weight:330.38rac Talinolol-d5
CAS:Controlled ProductApplications Labelled Talinolol. Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.
References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),Formula:C202H5H28N3O3Color and Shape:Off White CrystallineMolecular weight:368.52Monocarboxyisodecyl Phthalate-d4
CAS:Controlled ProductFormula:C18H20D4O6Color and Shape:Off-WhiteMolecular weight:340.4Foramsulfuron-d6
CAS:Controlled ProductFormula:C17D6H14N6O7SColor and Shape:White To Off-WhiteMolecular weight:458.48Testosterone Oleate
CAS:Controlled ProductFormula:C37H60O3Color and Shape:NeatMolecular weight:552.87Testosterone 17-Valerate
CAS:Controlled ProductApplications Testosterone ester. Testosterone 17-Valerate has been a useful compound in the development of immunochemical techniques for detection of anabolic androgenic steroids in food supplements.
References Ruelle, P., et al.: Int. J. Pharm., 157, 219 (1997), de la Torre, X., et al.: J. Pharm. Biomed. Anal., 24, 645 (2001), Adat, S., et al.: Lett. Drug Des. Discov., 1, 334 (2004), Holubova, B., et al.: Eur. Food Res. Technol., 245, 1011 (2019)Formula:C24H36O3Color and Shape:NeatMolecular weight:372.54Dimethomorph-d8
CAS:Controlled ProductApplications Labelled Dimethomorph (D460530). Agricultural fungicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),Formula:C21D8H14ClNO4Color and Shape:YellowMolecular weight:395.91Melagatran
CAS:Controlled ProductStability Hygroscopic
Applications Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic.
References Dewanjee, M., et al.: J. Nucl. Med., 22, 981 (1981), Goodman, S., et al.: J. Biomed. Mater. Res., 45, 240 (1999), Carlsson, S., et al.: Thromb. Res., 115, 9 (2005),Formula:C22H31N5O4Color and Shape:NeatMolecular weight:429.51De(cladinosyl) Clarithromycin
CAS:Controlled ProductImpurity Clarithromycin EP Impurity I
Applications De(cladinosyl) Clarithromycin (Clarithromycin EP Impurity I) is an impurity of Clarithromycin (C559750). De(cladinosyl) Clarithromycin showed significantly potent antibacterial activity against community acquired respiratory pathogens.
References Morimoto, S., et al.: J. Antibiot., 37, 187 (1984), Buxbaum, A., et al.: J. Antimicrob. Chemother., 52, 371 (2003), Westphal, J., et al.: Br. J. Clin. Pharmacol., 50, 285 (2000), Ma, Z., et al.: J. Med. Chem., 44, 4137 (2001),Formula:C30H55NO10Color and Shape:White To Off-WhiteMolecular weight:589.76Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt
CAS:Controlled ProductStability Hygroscopic, Light Sensitive, Temperature Sensitive
Applications Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt is a metabolite of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993),Formula:C24H23FNNaO3Color and Shape:NeatMolecular weight:415.43rac Galaxolidone-d6 (Mixture of Diastereomers)
CAS:Controlled ProductApplications rac Galaxolidone-d6 is the isotope labelled analog of rac Galaxolidone (G189005); a metabolite of Galaxolide (G189000/ G189001) which is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics, body lotions, deodorants, and detergents.
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y. et al.: Flav. Frag. J., 21, 822 (2006); Martin, C., et al.: Environ. Sci. Technol., 41, 5395 (2007); Reiner, J., et al.: Chemosphere, 62, 867 (2006)Formula:C18D6H18O2Color and Shape:NeatMolecular weight:278.426α-Hydroxy Androstenedione
CAS:Controlled ProductApplications A metabolite of Androstenedione (A637550).
References Gazdar, A., et al.: Cancer Res., 50, 5488 (1990), Levesque, J., et al.: Steroids, 70, 305 (2005), Lootens, L., et al.: Drug Metab. Dispos., 37, 2367 (2009),Formula:C19H26O3Color and Shape:NeatMolecular weight:302.41Azoxystrobin-d4
CAS:Controlled ProductApplications Strobilurin fungicide; inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Agricultural fungicide. Used in Pesticide detection.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),Formula:C222H4H13N3O5Color and Shape:NeatMolecular weight:407.413-Hydroxy Niclosamide (>90%)
CAS:Controlled ProductApplications 3-Hydroxy Niclosamide is a metabolite of Niclosamide(N395500) which is used as an anthelmintic drug (Cestodes).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Loftsson, T., et al.: J. Pharm. Sci., 85, 1017 (1996), Malik, N., et al.: Anti. Cancer Drugs, 10, 767 (1999), El-Sayed, M., et al.: Pharm. Res., 18, 23 (2001),Formula:C13H8Cl2N2O5Purity:>90%Color and Shape:NeatMolecular weight:343.119Diethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)
CAS:Controlled ProductApplications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. Tenofovir (T018500) impurity.
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);Formula:C20H33N6O9PColor and Shape:NeatMolecular weight:532.48Benfotiamine-Amide
CAS:Controlled ProductStability Hygroscopic
Applications Benfotiamine-Amide is an analog of Benfotiamine, which is a Vitamin B1 analog. Synthetic S-acyl derivative of Thiamine (T344185).
References Stracke, H., et al.: Exper. Clin. Endocrinol., Diabetes, 116, 600 (2008), Gohil, V., et al.: Nat., Biotechnol., 28, 249 (2010),Formula:C26H27N4O7PSColor and Shape:NeatMolecular weight:570.55Dextrorphan-d3 β-D-O-Glucuronide
CAS:Controlled ProductApplications A Labelled metabolite of Dextrorphan.
References Gonzalez, F., et al.: Nature, 331, 442 (1988), Meyer, U., et al.: Pharmacol. Ther., 46, 297 (1990), Rogers, J., et al.: Am. J. Med., 113, 746 (2002), Huang, W., et al.: Drug Metab. Dispos., 32, 1434 (2004),Formula:C232H3H28NO7Color and Shape:NeatMolecular weight:436.515-Trifluoromethyl-2-thio-pyridone
CAS:Controlled ProductFormula:C6H4F3NSColor and Shape:NeatMolecular weight:179.16Promecarb-d3
CAS:Controlled ProductApplications Promecarb-d3 is the isotope labelled analog of Promecarb (P756500); a carbamate pesticide.
References Knowles, C.O., et al.: B. Environ. Contam. Tox., 27, 529 (1981); Pacioni, N.L., et al.: Anal. Chim. Acta, 583, 63 (2007); Sanchez, F.G., et al.: Analyst, 116, 851 (1991)Formula:C122H3H14NO2Color and Shape:White To Off-WhiteMolecular weight:210.29Fruquintinib Trideuteromethylamide
CAS:Formula:C21H16D3N3O5Color and Shape:NeatMolecular weight:396.42Enzalutamide Carboxylic Acid
CAS:Applications Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer.
References Tomasz, M.B., et al.: New Engl, J. Med., 424, 371 (2014);Formula:C20H13F4N3O3SColor and Shape:NeatMolecular weight:451.391-Methyluric Acid-d3
CAS:Controlled ProductApplications A labelled metabolite of Theophylline.
References Chen, Y., et al.: Clin. Exper. Pharmacol. Physiol., 36, 828 (2009), Yu, C., et al.: J. Bacteriol., 191, 4624 (2009), Jetter, A., et al.: Eur. J. Clin. Pharmacol., 65, 411 (2009),Formula:C62H3H3N4O3Color and Shape:NeatMolecular weight:185.16

