Toxicology

<p>Applications Ergosterol biosynthesis inhibitor. Antifungal.<br>References Fung-Tomc., J.C., et al.: Antimicrob. Agents Chemother., 42, 313 (1988), Tsuruoka, A., et al.: Chem. Pharm. Bull., 46, 623 (1998), Gupta, A.K., et al.: J. Eur. Acad. Dermatol. Venereol., 19, 437 (2005),<br></p>

<p>Applications Colestilan, is a copolymer of 2-methyl-1H-imidazole and epichlorohydrin, and a bile acid sequestrans, that can be used for the treatment of hypercholesterolemia and dyslipidemia.<br>References Handelsman, Y., et al.: Diabetes Care, 34, S244 (2011);<br></p>

<p>Applications Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011)<br></p>

<p>Applications Mezlocillin Sodium is an antibacterial agent. Penicillin antibiotic effective against gram negative and gram positive bacteria.<br>References Sanders, C. et al.: J. Antimicrob. Chemother., 9, 15 (1982); Gasca, M. et al.: Am. J. Hosp. Pharm., 44, 574 (1987);<br></p>

<p>Applications Carboxyformamido Metazachlor Benzoic Acid is a metabolite of Metazachlor (M225855) which is a chloroacetanilide herbicide used on vegetable crops.<br>References Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009); Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010); Liu, B., et al.: J. Agric. Food Chem., 58, 2673 (2010);<br></p>

<p>Applications Diazoxon, is the oxidized form of Diazinon (D416880), an organophosphate insecticide. Diazoxon, is shown to be a more potent acetylcholinesterase (AChE) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lazarevic-Pasti, T. D., et al.: J. Electroanal. Chem., 692 (2013); Pasti, T. L., J. Environ. Protect. Ecology, 12, 1168 (2011);<br></p>

<p>Applications 10,11-Dihydro-10-hydroxy Carbamazepine O-β-D-Glucuronide is a metabolite of Carbamazepine (C175840).<br>References Burkhart, C., et al.: Clin. Exp. Allergy, 32, 1635 (2002), Pearce, R., et al.: Drug Metab. Dispos., 30, 1170 (2002), Naisbitt, D., et al.: Mol. Pharmacol., 63, 732 (2003), Farrell, J., et al.: Br. J. Clin. Pharmacol., 57, 690(2004),<br></p>

<p>Applications Labelled selective COX-2 inhibitor<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kulmacz, R.J., et al.: J. Biol. Chem., 264, 14136 (1989), Kalgutkar, A.S., et al.: J. Med. Chem., 43, 2860 (2000), Hata, A.N., et al.: Mol. Pharmacol., 67, 640 (2005), Tuccinardi, T., et al.: J. Med. Chem., 49, 984 (2006),<br></p>

<p>Applications Valifenalate is used in antibacterial compositions and method for controlling of plant disease with improved effect, fungicides preparation and phytosanitary treatments with fungicides.<br>References Gonnzalez-Alvarez, M., et al.: Food Chem., 131 826 (2012); Ogawa, M., et al.: PCT Int. Appl. (2016), WO 2016194971 A1 20161208<br></p>

<p>Applications It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Dual action VEGFR &amp; Raf inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000),<br></p>

<p>Applications Isotope labelled Bisphenol A β-D-Glucuronide is the glucuronide conjugate and metabolite of bisphenol A (B519495), an monomer used for policarbonate and epoxy resins.<br>References Zalko, D., et al.: Drug Metab. Dispos., 26, 28 (1998), Matthews, J., et al.: Chem. Res. Toxico., 14, 149 (2001), Kinjo, J., et al.: Biol. Pharm. Bull., 27, 185 (2004), Murata, M., et al.: Biochemistry, 43, 2569 (2004),<br></p>

<p>Applications 2-Methyl-4,6-dinitrophenol is a powerful toxicant with a long history of use in agriculture as a herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heusinkveld, H. J., et al.: Toxicol. Lett., 252, 62 (2016), Bettiol, C., et al.: Environ. Sci. Pollut. Res., 23, 7398 (2016)<br></p>

<p>Stability Moisture Sensitive<br>Applications Fosthietan is used as a nematicide, to protect soils and crops from nematodes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Choudhari, K. &amp; Koli, S.: Pesticides, 12, 29 (1978); King, P., et al.: Anim. Prod. Sci., 22, 209 (1982); Murthy, M., et al.: Pesticides, 19, 40 (1985)<br></p>

<p>Applications Maneb is a complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand. Maneb is a foliate fungicide used to protect crops in agriculture. Maneb is also useful in creating a toxin-based animal (usually primates) model of Parkinson's disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gent, D. et al.: Plant Disease, 87, 591 (2003); Valaskova, E. et al.: Agrochemia, 10, 178 (1970); Cicchetti F. et al.: Trends Pharmacol. Sci., 30, 475 (2009);<br></p>

<p>Applications A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.<br>References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)<br></p>

<p>Applications Fenpropidin-d10 is the labeled analogue of Fenpropidin (F249470), a fungicide.<br>References Leroux, P. Walker, A.: Eur. J. Plant Path., 135, 683 (2013); Zhao, H., et. al.: Ecotox. Environ. Safe., 77, 52 (2012)<br></p>

<p>Stability Hygroscopic<br>Applications GW 501516 Sulfone is a urinary metabolite of GW1516 (G931500), a drug candidate potentially enhancing athletic performance. GW 501516 Sulfoxide may be used or doping control purposes.<br>References Thevis, M., et. al.: Anal. Bioanal. Chem., 396, 2479 (2010)<br></p>

<p>Applications Used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0)<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>

<p>Stability Hygroscopic<br>Applications A sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>

<p>Applications Butyrophenone derivative having neuroleptic activity, used as an antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shimoda, K., et al.: Pharmacol. Toxicol., 83, 164 (1998), Sekine, Y., et al.: Eur. J. Clin. Pharmacol., 55, 583 (1999), Oka, T., et al.: Life Sci., 76, 225 (2004), Fujikawa, M., et al.: Prog. Neuro-Psychopharmacol. Biol. Psych., 32, 755 (2008),<br></p>

<p>Applications 5β-Androsterone β-D-Glucuronide is a glucuronide metabolite of Testosterone (T155000).<br>References Weusten, J., et al.: J. Steroid Biochem., 32, 689 (1989), Antignac, J., et al.: Steroids, 70, 205 (2005),<br></p>

<p>Stability Not stable in solution<br>Applications Flazasulfuron, is a Trifluoro-pyridine derivative acting as a pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deng, H., et al.: Zhejiang Huagong, 42, 1 (2011);<br></p>

<p>Applications 5,6-Dichloroindole-3-acetic acid and 4-Chloroindole-3-acetic acid are potent candidates for new rooting promoters without estrogenic activity. Plant growth stimulators.<br>References Pless, T., et al.: Plant Physiol., 74, 320 (1984), Igarashi, A., et al.: Biol. Pharm. Bull., 29, 2120 (2006), Liu, L., et al.: J. Agric. Food Chem., 56, 824 (2008),<br></p>

<p>Applications Mesosulfuron is used in synergistic herbicidal combinations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Baur, P., et al.: PCT Int. Appl. (2020), WO 2020173719 A1<br></p>

<p>Applications Bromadiolone is an anticoagulant rodenticide used on non-crop areas.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cherry, L., et al.: Toxicologist, 2, 108 (1992), Park, B., et al.: Biochem. Pharmacol., 31, 3635 (1992), Thijssen, H., et al.: Pestic Sci., 43, 73 (1995), Howald, G., et al.: Conserv. Biol., 21, 1258 (2007),<br></p>

<p>Applications (-)-Donepezil is an isomer of Donepezil (D531750), a nootropic, acting as an inhibitor of acetylcholinesterase.<br>References Ohnishi, A., et al.: J. Clin. Pharmacol., 33, 1086 (1993), Galli, A., et al.: Eur. J. Pharmacol., 270, 189 (1994)<br></p>

<p>Applications A B-Adrenergic receptor agonist. A Bronchodilator.<br>References Akhtar, S., et al.: J. Vet. Pharmacol. Ther., 21, 388 (1998), Kasprowicz, D.J., et al.: J. Immunol., 165, 680 (2000)<br></p>

<p>Applications An angiotensin-converting enzyme (ACE) inhibitor.<br></p>

<p>Applications Demeton-O is an organophosphorus pesticide found in some imported crops and fruits samples.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zvinavashe, E., et al.: Chemosphere, 75, 1531 (2009); Kobayashi, M., et al.: Shokuhin Eiseigaku Zasshi, 50, 261, (2009); Tamura, Y., et al.: Tokyo-to Kenko Anzen Kenkyu Senta Kenkyu Nenpo, 59, 199 (2009); Xu, H., et al.: Shijie Nongyao, 29, 42 (2007)<br></p>

<p>Applications Post-emergence sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gubbiga, N.G., et al.: Weed Technol., 9, 574 (1995), Ukrainczyk, L., et al.: J. Agric. Food Chem., 43, 855 (1995)<br></p>

<p>Applications 3,3’,5-Triiodo-L-thyronine O-β-D-Glucuronide Sodium Salt is the sodium salt of T795405, which is the O-glucuronide derivative of 3,3’,5-Triiodo-L-thyronine (T795380); one of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.<br>References Gross, J., et al.: Lancet I, 439 (1952); Roche, J., et al.: Biochim. Biophys. Acta, 11, 215 (1953); Chacon, M.A., et al.: J. Pediatr., 99, 758 (1981); Chopra, I.J., et al.: Thyroid, 6, 255 (1996)<br></p>

<p>Applications N,N-Diethyl-3-(mesitylsulphonyl)-1H-1,2,4-triazole-1-carboximidamide (Cafenstrole) (cas# 125306-83-4) is a useful research chemical.<br></p>

<p>Applications Fluazifop-P-butyl<br></p>

<p>Applications A labelled selective serotonin reuptake inhibitor (SSRI). Used as an antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wong, D.T., et al.: Life Sci., 15, 471 (1974), Goldstein, D.J., et al.: Br. J. Psychiat., 166, 660 (1995), Ni, Y.G., et al.: Proc. Nat. Acad. Sci. USA, 94, 2036 (1997)<br></p>

<p>Applications (8Z)-8-Dodecen-1-ol is a component of various insect sex pheromones.<br>References Kim, S.H., et al: Repub. Korean Kongkae Taeho Kongbo, KR 2015046436 A 20150430 (2015); Ma, R., et al.: Faming Zhuanli Shenqing, CN 104177256 A 20141203 (2014)<br></p>

<p>Stability Hygroscopic<br>Applications An impurity in the synthesis of Erythromycin (E649950). An antibacterial.<br>References Zhang, L. et al.: J. Antibio., 64, 243 (2011); Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),<br></p>

<p>Stability Hygroscopic<br>Applications Ethanolamine-13C2 Hydrochloride is the labeled analogue of Ethanolamine (E676500), which is used in the preparation of various pharmaceutical compounds and inhibitors. Ethanolamine-13C2, is also a 13C-labeled lipid precursor, used for the detection of phospholipid metabolism and the synthesis of phosphatidylethanolamine in T47D human breast cancer cells.<br>References Ronen, S. M., et al.: Magnetic Resonance Med., 25, 384 (1992); Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);<br></p>

<p>Applications Antitrypanosomal agent.<br>References Tettey, J., et al.: J. Pharm. Biomed. Anal., 21, 1 (1999), Newton, P., et al.: Lancet Infect. Dis., 6, 602 (2006),<br></p>

<p>Applications Glucocorticoid receptor binding.A representative lots showed approximately 10% d8.<br>References Gazdar, A., et al.: Cancer Res., 50, 5488, (1990), Bird, I., et al.: Endocrinology, 134, 2468 (1994), Auchus, R., et al.: J. Biol. Chem., 273, 3158 (1998), Dardis, A., et al.: J. Endocrinol., 179, 131 (2003),<br></p>

<p>Stability Light and Temperature Sensitive<br>Applications A synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time.<br>References Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008); Scorza, R. et al.: J. Rheutamol., 24, 1944 (1997); Melillo, E. et al.: Int. J. Microcircul. Clin. Exp., 15, 60 (1995);<br></p>

<p>Applications Chlorthion is a pesticide found in the study of agrochemical bioregulators.<br>References Yan, D. Y., Huanjing Huaxue, 25, 220-224, (2006)<br></p>

<p>Applications Isotope labelled N-Acetylaminomethylphosphoric Acid is been found to show inhibitory properties towards ureases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Berlicki, L. et al.: Amino Acids, 42, 1937 (2012);<br></p>

<p>Applications Oryzalin is an herbicide of the dinitroaniline class of compounds which works through the disruption of microtubules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liang, Q. et al.: Plant. Biotechnol., 33, 59 (2016);<br></p>

<p>Applications Labelled Ceftiofur (C244700). An antibacterial.<br>References Yancey, R.J., et al.: Am. J. Vet. Res., 48, 1050 (1987)<br></p>

<p>Applications Barbadin is a selective β-arrestin/β2-adaptin inhibitor. It selectively inhibits the interaction between b-arrestin and the b2-adaptin subunit of the clathrin adaptor protein AP2 without affecting the formation of receptor/b-arrestin complexes.<br>References Beautrait, A., et al.: Nat Commun. 8, 15054 (2017)<br></p>

<p>Applications 6-Hydroxy Bromantane is a metabolite of Bromantane (B678450).<br>References Bi, H., et al.: J. Steroid Biochem. Mol. Biol., 42, 229 (1992), Pozo, O., et al.: Anal. Bioanal. Chem., 389, 1209 (2007), Kiousi, P., et al.: Bioanalysis, 1, 1209 (2009),<br></p>

<p>Applications Labelled Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rooks, W.H., et al.: Agents Actions, 12, 684 (1982), Guzman, A., et al.: J. Med. Chem., 29, 589 (1986), McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1986),<br></p>

<p>Applications Fipronil Sulfone is a sulfone metabolite of the insecticide Fipronil (F342200). Fipronil Sulfone blocks γ-aminobutyric acid- and glutamate-activated chloride channels in mammalian and insect neurons.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, X. et al.: J. Pharmacol. Exp. Therap., 314, 363 (2005); Mulrooney, J.E. et al.: J. Econ. Entomol., 92, 1364 (1999); Hainzl, D. et al.: Chem. Res. Toxicol., 11, 1529 (1998);<br></p>

<p>Applications Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. It is a COVID19-related research product.<br>References Oestereich, L., et al.: Antiviral Res., 105, 17 (2014); Baranovich, T., et al.: J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014)<br></p>

<p>Applications A metabolite of the fluorinated quinolone antibacterial Ciprofloxacin.<br>References Tiefenbacher, E., et al.: J. Pharm. Sci., 83, 463 (1994), Parshikov, I., et al.: App. Microbiol. Biotechnol., 56, 474 (2001),<br></p>

<p>Applications A novel anti-tuberculosis drug.<br>References Diacon, A.H. et al.: Antimicrob. Anents Chemother., 54, 3402 (2010); Dogra, M. et al.: Br. J. Pharmacol., 162, 226 (2010); Ginsberg, A.M. et al.: Antimicrob. Agents Chemother., 53, 3720 (2009);<br></p>

<p>Stability Hygrscopic<br>Applications A metabolite of Caffeic acid.<br>References Zhu, B., et al.: J. Biol. Chem., 269, 292 (1994), Azuma, K., et al.: J. Agric. Food Chem., 48, 5496 (2000), Stark, T., et al.: J. Agric. Food Chem., 54, 5530 (2006), Hensel, A., et al.: Planta Med., 73, 142 (2007),<br></p>

<p>Applications Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.<br>References Kim, T.E., et al.: Drugs, 6, 886 (2003), Wood, E.R., et al.: Cancer Res., 64, 6652 (2004), Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005),<br></p>

<p>Applications Labelled Pyruvic acid (P998900). Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. The liver can convert Pyruvic acid to alanine by amination. A diagnostic agent for Parkinson disease.<br>References Wenzel, A., et al.: J. Neurosci., 21, 53 (2001), Martinez., et al.: Development, 6, 851 (2002), Nakayama, K., et al.: J. Biochem., 146, 757 (2009), Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2009),<br></p>

<p>Applications 8-Hydroxyhydromorphone is derived from Benzylmorphine (B286778), which is an opioid alkaloid that is a derivative of Morphine (M652285).<br>References Buchwald, M.E., et al.: J. Pharmacol. Exp. Ther., 71, 197 (1941); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 17, 259 (1988);<br></p>

<p>Applications A metabolite of 17β-Nandrolone (N315000).<br></p>

<p>Applications Phenothrin is a pesticide used in the control of pests and insects. It is used in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, Y. et al.: Chemopshere, 90, 848 (2013); Hirahara, Y. et al.: Japan. J. Toxicol. Env. Health, 44, 451 (1998);<br></p>

<p>Applications Glibornuride has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. Glibornuride is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mielsen-Kudsk, J.E., Thirstrup, S.: Pulm. Pharmacol., 6, 185 (1993); Bodmer, M., et. al.: Diabetes Care, 31, 2086 (2008)<br></p>

<p>Applications Istradefylline is a selective A(2A) antagonist used in the treatment of Parkinson’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dungo, R. et al.: Drugs., 73, 875 (2013); Stoessel, A. et al.: J. Med. Chem., 56, 4580 (2013);<br></p>

<p>Applications Tralomethrin-d5, is the labeled analogue of Tralomethrin (T712400), which is a pyrethroid insecticide. It is effective against most members of class Arachnida as well as insects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laskowski, D.A., et al.: Review Env. Conatmin. Toxic., 174, 49 (2002); Tanaka, Y., et al.: Shokuhin Eiseigaku Zasshi, 41, 335 (200);<br></p>

<p>Stability Hygroscopic<br>Applications Asenapine N-β-D-Glucuronide is a metabolite of Asenapine (A788000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Metyrapone acts as a glucocorticoid synthesis inhibitor, maintaining stress-hormone levels.<br>References Keller, C. et al.: Drug. Alc. Dep., 133, 405 (2013); Vilela, F. et al.: Neuroendocrinol., 97, 322 (2013);<br></p>

<p>Applications Diethanolamine similar to triethanolamine (T775580) is used as a surfactant. It also has the potential to be a corrosion inhibitor by means of chemisorption. This is the labelled analog.<br>References Bhajiwala, H.M et al.: Bull. Electrochem., 17, 441 (2001); Yu, J. et al.: Thin. Solid. Films., 379, 7 (2000);<br></p>

<p>Applications Labelled Deshydroxyethoxy Ticagrelor analog of Ticagrelor (T437700) an antiplatelet agent, and preventative in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases.<br>References Zhang, H. et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>

<p>Applications Labelled Spirotetramat (S683300). Spirotetramat is a synergistic insecticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Byrne, F., et al.: Crop. Prot., 25, 831 (2006), Kanrar, B., et al.: Bull Environ. Contam. Toxicol., 77, 631 (2006), Venkateswarlu, P., et al.: Food Chem., 105, 1760 (2007), Khay, S., et al.: Biomed. Chromatogr., 22, 581 (2008),<br></p>

<p>Applications Herbicide, active by perturbing cell membranes<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009), Bollman, S., et al.: Weed Technol., 23, 264 (2009), Goudarzi, N., et al.: J. Agric. Food Chem., 57, 7153 (2009),<br></p>

<p>Applications Piperonyl Butoxide-d9 is a deuterated analog of Piperonyl Butoxide an Insecticide synergist, especially for pyrethroids and rotenone. Also used in Cannabis testing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jiang, W., et al.: J. Econ. Entomol., 103, 1365 (2010), Markussen, M., et al.: Pest. Biochem. Physiol., 98, 50 (2010),<br></p>

<p>Applications Tetradifon is an acaricide and ovicide. Also, Tetradifon possessed nephrotoxic by promoting kidney morphometric and functional damage and depleting renal antioxidant defense system in rats.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Badraoui, R., et al.: Exp Toxicol Pathol., 64, 645-50 (2012);<br></p>

<p>Applications An anti-inflammatory and analgesic agent. Anesthetic (local).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, et al.: Br. J. Anaesth., 43, 33 (1971), Tullar, et al.: J. Med. Chem., 14, 891 (1971), Aberg, G., et al.: Acta Pharmacol. Toxicol., 31, 273 (1972),<br></p>

<p>Applications Sedative, hypnotic.Controlled substance (depressant).<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>

<p>Applications Aminopyralid is used as a herbicide for control weeds and arthropods.<br>References Mitich, L., et al.: Weed Technol., 14, 231 (2000), Berisford, Y., et al.: Weed Sci., 54, 391 (2006), Westra, P., et al.: Proc. Weed Sci. Soc. America, 49, 407 (2009),<br></p>

<p>Applications Ethyl Indole-3-acetate is a compound used in the synthesis of 9H-Pyrrolo[1,2-α]Indoles via Michael Addition-Condensation with α,β-Unsaturated Ketimines.<br>References Zhang, M., et al.: J. Heterocyclic Chem. (2016)<br></p>