Biochemicals and Reagents

<p>H-RKELTDFLQAETDKL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-RKELTDFLQAETDKL-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-RKELTDFLQAETDKL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-RKELTDFLQAETDKL-OH at the technical inquiry form on this page</p>

<p>H-YRNIEFFTKNSAFPK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-YRNIEFFTKNSAFPK-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-YRNIEFFTKNSAFPK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-YRNIEFFTKNSAFPK-OH at the technical inquiry form on this page</p>

<p>Endoglin is a protein that is encoded by the ENG gene and is expressed in most tissues. It has been shown to be an antagonist of angiopoietin-1 and angiopoietin-2, which are proteins that regulate the growth of blood vessels and act as a tumor suppressor. Endoglin has also been found to be expressed in neoplastic cells, including cancer cells. The physiological role of endoglin is not well understood, but it may play a role in cell migration and invasion, angiogenesis, or other cellular functions.</p>

6-Thioguanine is a purine analog used in the therapy for leukemia and for remission consolidation in patients with acute nonlymphocytic anemia. This drug also has antimetabolite action. It replaces guanine during DNA replication. This substitution disrupts the accurate pairing of DNA bases, leading to errors in DNA replication and hinders cell division.

<p>H-CGGESPHSKRPFSQGS-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-CGGESPHSKRPFSQGS-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-CGGESPHSKRPFSQGS-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-CGGESPHSKRPFSQGS-OH at the technical inquiry form on this page</p>

<p>H-EAAFGPGTGPIWLNEIK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-EAAFGPGTGPIWLNEIK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-EAAFGPGTGPIWLNEIK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-EAAFGPGTGPIWLNEIK-OH at the technical inquiry form on this page</p>

<p>Topoisomerase II inhibitor; daunorubicin analog; anti-leukemic; anthracycline</p>

<p>Please enquire for more information about Cy3 Acid(tri SO3) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Nisoldipine is a calcium channel blocker that is used to treat hypertension. It acts on vascular smooth muscle cells by blocking voltage-gated L-type calcium channels. By inhibiting the influx of calcium in smooth muscle cells, Nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction.</p>

<p>Ac-VHVHVGVHVH-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-VHVHVGVHVH-NH2 is provided at greater that &gt;98% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-VHVHVGVHVH-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-VHVHVGVHVH-NH2 at the technical inquiry form on this page</p>

<p>H-LPPYLYT-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-LPPYLYT-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-LPPYLYT-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-LPPYLYT-OH at the technical inquiry form on this page</p>

<p>H-Gly-Gly-His-Gly-OH is a tripeptide with a molecular weight of 778.09 g/mol. It is crosslinked to the side chain of lysine residues and can be used for the crosslinking of protein fibers, such as wool or silk, to form hydrophobic materials that are both resistant to shrinkage and have good thermal stability. The crosslinking reaction can be achieved by either the hypobromous acid oxidation or by inorganic oxidants such as hydrogen peroxide. H-Gly-Gly-His-Gly-OH has axial reactive radicals at its center which facilitates the formation of covalent links with other molecules.br&gt;<br>br&gt;<br>The yield depends on the type of reactant used and ranges from 47% (hydrogen peroxide) to 60% (hypobromous acid). The residue obtained after hydrolysis is an alpha amino acid consisting of</p>

<p>DPP-4 enzyme inhibitor; anti-diabetic</p>

<p>H-SVINDPIYK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-SVINDPIYK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-SVINDPIYK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-SVINDPIYK-OH at the technical inquiry form on this page</p>

<p>H-VSCTYDALK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VSCTYDALK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VSCTYDALK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VSCTYDALK-OH at the technical inquiry form on this page</p>

<p>H-ESDNSYVTLK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ESDNSYVTLK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ESDNSYVTLK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ESDNSYVTLK-OH at the technical inquiry form on this page</p>

<p>H-GHEYTNIK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-GHEYTNIK-OH is provided at greater that Crude (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-GHEYTNIK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-GHEYTNIK-OH at the technical inquiry form on this page</p>

<p>Ci-IP3/PM is a fluorescent calcium ionophore. It is used to measure the intracellular calcium in cells, and is also used for staining and studying mitochondria. Ci-IP3/PM can be used to evaluate the function of receptor-mediated endocytosis. The ci-IP3/PM binds to extracellular Ca2+ by chelation, which prevents it from entering the cell. This leads to an increase in cytosolic Ca2+ concentration, which triggers sequestration of intracellular Ca2+. Transient increases in cytosolic Ca2+ concentrations are observed when cells are stimulated with receptor agonists. When the stimulus is removed, release of sequestered Ca2+ occurs, leading to a decrease in cytosolic Ca2+.</p>

<p>CI Reactive Blue 203 is a reactive dye that changes color from blue to purple when heated. It is used in forensics, where it can be used to detect the presence of alkali metal ions. CI Reactive Blue 203 has been shown to react with fungal cells and peroxidase enzymes, yielding a violet color. This dye is also used as a surfactant, thickener, and vinyl stabilizer in textile production. CI Reactive Blue 203 has been shown to bind to antibodies and can be used for staining purposes in histology. This dye binds to methoxy groups on proteins and can be used for detection purposes in ELISA tests.</p>

<p>CMV IgM seroconversion panel 6 is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about CMV IgM seroconversion panel 6 including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Ac-QQGLPRAAGGC-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-QQGLPRAAGGC-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-QQGLPRAAGGC-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-QQGLPRAAGGC-NH2 at the technical inquiry form on this page</p>

<p>H-Glu-AMC is a fluorescent substrate for the aminopeptidases that can be used for their detection in extracellular spaces. H-Glu-AMC is also a model substrate for homopolymeric strings, which are detectable by microscopy. The pathogenesis of hyopneumoniae has been shown to be associated with an increase in aminopeptidase activity and tissue plasminogen activator on the surface of the bacteria. It has been shown that these enzymes are responsible for cleaving proline from the amino acid chain, resulting in a break in the peptide bond.</p>

<p>A potent antagonist of androgen receptor with IC50 value of 16 nM. Binds androgen receptors, thereby inhibiting nuclear translocation, DNA binding and transcriptional activation. Has therapeutic applications in non-metastatic, castration-resistant prostate cancer.</p>

<p>H-GVLLPQK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-GVLLPQK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-GVLLPQK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-GVLLPQK-OH at the technical inquiry form on this page</p>

<p>H-VLFGLGFAI-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VLFGLGFAI-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VLFGLGFAI-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VLFGLGFAI-OH at the technical inquiry form on this page</p>

<p>H-KVLVEVLADPLDHR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KVLVEVLADPLDHR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KVLVEVLADPLDHR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KVLVEVLADPLDHR-OH at the technical inquiry form on this page</p>

<p>Please enquire for more information about C.I.Disperse Orange 32 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Inhibitor of the Forkhead box M1 (FOXM1), an oncogene and a transcription factor regulating cell cycle progression, DNA damage repair and cell renewal. RCM 1 weakens the FOXM1 activity by inhibiting its nuclear localisation and increasing its degradation in proteasomes. The compound showed potential for asthma treatment since it inhibited goblet cell metaplasia and IL-13 signalling in mice.</p>

CID 4921527 is a high-purity research tool that is an inhibitor of ion channels. It binds to the ligand binding site of the Ligand and inhibits activation of the receptor by its natural ligands. CID 4921527 is used to study protein interactions and protein-protein interactions. This compound has been shown to be an activator, as it increases the activity of peptides and antibodies in a wide range of assays, including enzyme-linked immunosorbent assay (ELISA) for the detection of proteins.

<p>PPARγ antagonist</p>

<p>Inhibits binding of endogenous ligands to peroxisome proliferator-activated receptor gamma (PPARγ), blocking its activation and transcription. Unlike orthosteric antagonists GW 9662 and T 0070907, SR 16832 blocks both allosteric and orthosteric activation of PPARγ.</p>

Inhibitor of folate synthesis; folic acid analogue

<p>H-FDMELDDLPK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-FDMELDDLPK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-FDMELDDLPK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-FDMELDDLPK-OH at the technical inquiry form on this page</p>

<p>H-PASALCARL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-PASALCARL-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-PASALCARL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-PASALCARL-OH at the technical inquiry form on this page</p>

<p>Antagonist of ÎŽ2 opioid receptor</p>

<p>H-DMEDEEADLRRAIQLSMQGS-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-DMEDEEADLRRAIQLSMQGS-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-DMEDEEADLRRAIQLSMQGS-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-DMEDEEADLRRAIQLSMQGS-OH at the technical inquiry form on this page</p>

<p>H-KQLVIYEEISDPPEDDE-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KQLVIYEEISDPPEDDE-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KQLVIYEEISDPPEDDE-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KQLVIYEEISDPPEDDE-OH at the technical inquiry form on this page</p>

<p>H-IFYCTFQRSGPEENNTAE-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-IFYCTFQRSGPEENNTAE-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-IFYCTFQRSGPEENNTAE-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-IFYCTFQRSGPEENNTAE-NH2 at the technical inquiry form on this page</p>

<p>Inhibitor of lactate uptake and efflux via monocarboxylate transporter MCT1. The blockade of lactate transport with BAY 8002 leads to accumulation of lactate and pyruvate in cells. The MCT1 inhibition decreased tumour growth most effectively in diffuse large B-cell lymphoma cell lines and in subsets of solid tumour models.</p>

<p>H-GPMAVVQSVPK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-GPMAVVQSVPK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-GPMAVVQSVPK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-GPMAVVQSVPK-OH at the technical inquiry form on this page</p>

<p>Tolbutamide sodium is an oral hypoglycemic agent, belonging to the class of sulfonylureas. It is a synthetic compound derived from the sulfonamide class, specifically designed to stimulate the release of insulin from pancreatic beta cells. The mode of action is primarily through the inhibition of ATP-sensitive potassium channels in the pancreatic islet cells, which leads to an increase in intracellular calcium concentration and subsequent insulin release.</p>

<p>H-LLDEILGVGVR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-LLDEILGVGVR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-LLDEILGVGVR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-LLDEILGVGVR-OH at the technical inquiry form on this page</p>

<p>H-NVLAFGFAL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-NVLAFGFAL-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-NVLAFGFAL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-NVLAFGFAL-OH at the technical inquiry form on this page</p>

<p>H-SSQQNSGAR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-SSQQNSGAR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-SSQQNSGAR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-SSQQNSGAR-OH at the technical inquiry form on this page</p>

<p>Napsagatran is a human, activated, orally bioavailable, small molecule that acts as an oral thromboplastin inhibitor. It is metabolized by esterases to form the active drug napsagatran etexilate. Napsagatran inhibits the activity of heparin-induced thrombocytopenia (HIT) and has been shown to be effective in clinical studies. The pharmacokinetic properties of napsagatran have been characterized in humans using a pharmacokinetic study design with a two-way crossover design. A kinetic study was carried out using flow system analysis to determine the time course of plasma concentrations following administration of napsagatran etexilate.</p>

IgM Mouse Monoclonal Antibody is an antigen for use in IVD applications. Please enquire for more information about IgM Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page.

<p>H-AESRAEKNRLWGPGSC-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AESRAEKNRLWGPGSC-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AESRAEKNRLWGPGSC-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AESRAEKNRLWGPGSC-OH at the technical inquiry form on this page</p>

<p>H-FALNGEEFMNFDLK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-FALNGEEFMNFDLK-OH is provided at greater that &gt;98% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-FALNGEEFMNFDLK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-FALNGEEFMNFDLK-OH at the technical inquiry form on this page</p>

<p>Please enquire for more information about Thyroglobulin Antibody Positive Human Plasma including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Research Peptide, 95%.</p>

<p>Trail human is a protein that is encoded by the TRAIL gene. Trail human binds to death receptor 4 (DR4) and DR5 and mediates apoptosis. It has been shown to be expressed in leukemia cells, where it may be involved in the regulation of genes involved in apoptosis. Trail human also has an anti-tumorigenic effect on brain tumors, as it inhibits tumor growth without affecting normal tissue. Trail human has been shown to inhibit cancer cell proliferation by blocking the synthesis of proteins required for DNA replication and cell division. Trail human also induces apoptosis through activation of caspase 3 and 9 by binding to their respective receptors DR4 and DR5.</p>

<p>H-Arg-AMC hydrochloride is a denaturing agent that is used to prevent the proteolytic degradation of proteins in muscle and other tissues. It has been shown to inhibit the activity of lipase, myofibrillar, and endoplasmic enzymes. H-Arg-AMC hydrochloride also has cancer preventive effects by inhibiting the growth of tumor cells. H-Arg-AMC hydrochloride has been shown to have high values in notochord markers, supplementing cytosolic markers, and endogenous markers.</p>

<p>Cofactor for nitric oxide synthetase and Phe, Tyr and Trp hydroxylases</p>

<p>H-AEKKLEERRKRRRFLSPQQP-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AEKKLEERRKRRRFLSPQQP-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AEKKLEERRKRRRFLSPQQP-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AEKKLEERRKRRRFLSPQQP-OH at the technical inquiry form on this page</p>

<p>H-LDVHYAPTIR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-LDVHYAPTIR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-LDVHYAPTIR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-LDVHYAPTIR-OH at the technical inquiry form on this page</p>

<p>Inhibitor of ABC transporters; oral bioenhancer for anti-cancer therapy</p>

<p>Please enquire for more information about IgG Fc Goat Polyclonal Antibody, Affinity Purified including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Research peptide, 95% TFA salt

<p>Amino acids 40-54 derived from the Immunogenic Myelin Oligodendrocyte protein (MOG). Produced by oligodendrocytes, MOG is an integral part of the oligodendrocyte surface membrane, located in the central nervous system (CNS) and plays an important role in the maintenance and disintegration of the myelin sheath. Unique within their immunoglobulin superfamily, MOG is composed of a transmembrane hydrophobic domain, an extracellular immunoglobulin variable (IgV) domain, a short cytoplasmic loop and within the membrane bilayer there is a second hydrophobic region and after this, a cytoplasmic end. In addition to 218 amino acids of the mature MOG protein, it contains a 29 amino acids long signal peptide.<br>MOG has not only been found to be expressed in the CNS but also at low levels in the peripheral nervous system. Generally MOG is expressed during myelination and functions to maintain the myelin sheath’s structurally integrity through mediating interactions between the myelin and the immune system. This is possible due to its adhesion characteristics and its external location which makes it accessible to antibodies and T-cells. Furthermore is has been suggested that MOG is involved in regulating oligodendrocyte microtubule stability and it can be used as a differentiation marker for oligodendrocyte maturation.Myelin forms a lipid layer around neurons which insulates them. MOG has immunodmainant epitopes: 1-22; 35-55 and 92-106 and this is located at the dimer interface which is formed by MOG IgV domains forming a dimer. These MOG epitopes are recognized by encepalitogenic T cells as foreign antigens. As a result demyelination occurs and this happens in the disease state of Multiple Sclerosis (MS).<br>As MOG is associated with inflammatory demyelinating diseases within the CNS such as neuromyelitis optica spectrum disorders and acute disseminated encephalomyelitis, this MOG (40-54) product can be used to induce these disease states in animals models.<br>One-Letter Formula: YRSPFSRVVHLYRNG</p>

<p>H-AEDTAVYYCAR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AEDTAVYYCAR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AEDTAVYYCAR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AEDTAVYYCAR-OH at the technical inquiry form on this page</p>

<p>Lodoxamide is a type of ophthalmic medication known as a mast cell stabilizer, which is chemically synthesized from non-steroidal structures. It works by inhibiting the degranulation of sensitized mast cells and subsequent release of inflammatory mediators such as histamine. This action is achieved through the stabilization of the cell membrane of mast cells, thus preventing cellular activation.</p>

<p>H-AKFVAAWTLKAAA-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AKFVAAWTLKAAA-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AKFVAAWTLKAAA-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AKFVAAWTLKAAA-OH at the technical inquiry form on this page</p>

<p>H-GLLLTRDGGNNNNGS-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-GLLLTRDGGNNNNGS-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-GLLLTRDGGNNNNGS-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-GLLLTRDGGNNNNGS-OH at the technical inquiry form on this page</p>

<p>Phytosulfokine (PSK) was introduced in 1996 by Matsubayashi and Sakagami of Nagoya University.  It is the world's first peptide phytohormone to be isolated from asparagus culture medium. Tyr undergoes post-translational sulfation modification, which is essential for bioactivity. As an example of oxidative peptides showing bioactivity, in animals, CCK-octapeptide (26-33) (sulfated form), PCK-4100-V, CCK-33 (Human), PCK-4201-S and CCK-33 (Porcine), PCK-4176-S are known, but they were first found in plants. The functions of phytosulfokine are i) plant cell proliferation and differentiation activity acting at nanomolar concentrations ii) chlorophyll synthesis-promoting activityiii) formation of adventitious roots and buds iv) adventitious embryogenesisv) involvement in disease resistance The active expression of these PSKs is accompanied by membrane-bound LRR receptors, which are PSK receptors. Leucine-rich repeat receptor-like kinase is involved.</p>

<p>Lomustine is an alkylating agent that is used as chemotherapy for treating metastatic brain tumors and relapsed Hodgkin’s disease in combination with radiation treatments. This drug causes alkylation and cross-linking of DNA, thus inducing cytotoxicity. Furthermore, this drug inhibits DNA synthesis.</p>

<p>Mirtazapine is a potent and selective antagonist of the presynaptic α2-adrenergic receptors. It is an atypical tetracyclic antidepressant and is used primarily to treat depression. Mirtazapine inhibits the central presynaptic α2-adrenergic receptors, which causes an increased release of serotonin and norepinephrine.</p>

<p>H-LLIYDTSK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-LLIYDTSK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-LLIYDTSK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-LLIYDTSK-OH at the technical inquiry form on this page</p>

<p>H-VLAFGFAL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VLAFGFAL-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VLAFGFAL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VLAFGFAL-OH at the technical inquiry form on this page</p>

<p>Inhibitor of kinase domain of TGF-β receptor type 1</p>

<p>H-GAGSSQHQER-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-GAGSSQHQER-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-GAGSSQHQER-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-GAGSSQHQER-OH at the technical inquiry form on this page</p>

<p>Piracetam is a nootropic drug that is used for the treatment of sickle cell disease, alcohol dependence and as a cognitive enhancer. This drug is a cyclic derivative of GABA and has neuroprotective and anticonvulsant properties. Piracetam has been said to improve neuronal plasticity.</p>

<p>H-SGPASALCA-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-SGPASALCA-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-SGPASALCA-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-SGPASALCA-OH at the technical inquiry form on this page</p>

<p>H-ALELLMAANFLDC-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ALELLMAANFLDC-NH2 is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ALELLMAANFLDC-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ALELLMAANFLDC-NH2 at the technical inquiry form on this page</p>

<p>Eotaxin is a human basic protein that belongs to the eosinophil cationic protein family. It stimulates the growth of cells and promotes tissue repair. Eotaxin also has a role in the immune response, as it is able to bind to and activate macrophages, neutrophils, and lymphocytes. Eotaxin is found in increased concentrations in inflammatory bowel disease (IBD), where it may play a role in the recruitment of inflammatory cells. The signal peptide sequence of eotaxin is cleaved by signal peptidase I and II during transit through the Golgi apparatus, yielding an active form that can be processed into mature eotaxin by several proteases. This active form can be detected by polymerase chain reaction (PCR) amplification of DNA isolated from human peripheral blood leukocytes or colonic biopsies. Eotaxin has been shown to have anti-inflammatory effects on both healthy tissues and those with</p>

<p>H-TDAIFDEWLKRNNPS-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-TDAIFDEWLKRNNPS-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-TDAIFDEWLKRNNPS-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-TDAIFDEWLKRNNPS-OH at the technical inquiry form on this page</p>

<p>Ac-SRPSPFDLFIRKSC-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-SRPSPFDLFIRKSC-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-SRPSPFDLFIRKSC-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-SRPSPFDLFIRKSC-NH2 at the technical inquiry form on this page</p>

<p>H-AFVTWHRYHLLWLER-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AFVTWHRYHLLWLER-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AFVTWHRYHLLWLER-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AFVTWHRYHLLWLER-OH at the technical inquiry form on this page</p>

<p>H-AWGNNQDGVVASQPAR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AWGNNQDGVVASQPAR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AWGNNQDGVVASQPAR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AWGNNQDGVVASQPAR-OH at the technical inquiry form on this page</p>

<p>H-WVDGTDYETGFK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-WVDGTDYETGFK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-WVDGTDYETGFK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-WVDGTDYETGFK-OH at the technical inquiry form on this page</p>

<p>Ac-CQDLVPGSPDDSHPK-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-CQDLVPGSPDDSHPK-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-CQDLVPGSPDDSHPK-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-CQDLVPGSPDDSHPK-NH2 at the technical inquiry form on this page</p>

<p>Ac-ERQRRNELKRSFFALADQI-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-ERQRRNELKRSFFALADQI-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-ERQRRNELKRSFFALADQI-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-ERQRRNELKRSFFALADQI-OH at the technical inquiry form on this page</p>

<p>H-CIQNTGDYYDLYGGEK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-CIQNTGDYYDLYGGEK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-CIQNTGDYYDLYGGEK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-CIQNTGDYYDLYGGEK-OH at the technical inquiry form on this page</p>

<p>H-HTVGHIILSEHK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-HTVGHIILSEHK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-HTVGHIILSEHK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-HTVGHIILSEHK-OH at the technical inquiry form on this page</p>

<p>Inhibitor of dihydroorotate dehydrogenase; broad spectrum antiviral</p>

<p>Inhibitor of polycomb protein EED</p>

<p>H-IQFKPDDGTTPDR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-IQFKPDDGTTPDR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-IQFKPDDGTTPDR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-IQFKPDDGTTPDR-OH at the technical inquiry form on this page</p>

HBsAg antibody (Subtype ad/ay) was raised in goat using human hepatitis B surface antigen as the immunogen. The term HBsAg collectively refers to the three particle forms: Dane, filamentous, and spherical of the Hepatitis B (HB) virus which are made up of small HBs proteins (SHBs), middle HBs proteins (MHBs), and large HBs proteins (LHBs). These HBsAg proteins envelop the viral nucleocapsid and bind to the viral core. The LHB has a pre-S1, pre-S2, and S domain, the MHB does not have this pre-S1 domain while SHBs only have the S domain. The S domain's ability to form disulfide cross-linked dimers allows Dane particles of the HBsAg to interact with sulfated proteoglycans on host cells, resulting in HB infection. Furthermore, residues 2-48 which make up a conserved N-terminal sequence on the pre-S1 domain, allow HBsAg to bind to the Na+-Taurocholate Co-transporter Polypeptide (NTCP) on hepatocytes. This antibody has potential for use in research and diagnostic applications of HB infection, a necro-inflammatory liver disease that can cause liver cirrhosis and hepatocellular carcinoma.

<p>Inhibitor of fibroblast growth factor receptors (FGFR1, FGFR2 and FGFR3). Demonstrated anti-tumor effects in pre-clinical models of FGFR-driven tumors. AZD 4547 resulted in tumor progression when applied on a patient-derived model of FGFR1-amplified squamous cell lung disease. Antineoplastic effects also observed in FGFR2-amplified gastric cancer.</p>

<p>Mouse Anti-Human Troponin I</p>

<p>Rotavirus VP6 Antigen, Recombinant is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Rotavirus VP6 Antigen, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>BRD 0705 is a potent inhibitor of autophagy that targets the protein ATG3. This compound was shown to inhibit proliferation and induce apoptosis in cancer cells, as well as reducing the number of β-cells in the pancreas. The mechanism for BRD 0705's effects on cell death may be through its ability to inhibit splicing and promote nonsense-mediated decay of mRNAs, which leads to reduced protein synthesis, cell death, and tumorigenesis.<br>BRD 0705 has also been shown to be effective against human diabetes due to its ability to inhibit β-cell death by inhibiting autophagy.</p>

<p>H-DTSATTAYMELSSLR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-DTSATTAYMELSSLR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-DTSATTAYMELSSLR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-DTSATTAYMELSSLR-OH at the technical inquiry form on this page</p>

<p>Angiotensin-converting enzyme inhibitor</p>

<p>Pi3K (P110-β/P85-β), active, His tagged human is a high purity, recombinant protein. Pi3K (P110-β/P85-β) is an activator of the phosphatidylinositol 3-kinase (PI3K) enzyme. It has been shown to be involved in many cellular processes, including cell proliferation and differentiation, as well as in the regulation of insulin secretion. This protein also interacts with other proteins such as PLCγ1, PDCD4, and PTEN.</p>

<p>Rostaporfin is an analog of the drug bevacizumab, which is used to treat a number of diseases. Rostaporfin has been shown to inhibit angiogenesis and reduce ocular neovascularization in a rat model of choroidal neovascularization. It also inhibits growth factor-induced proliferation and migration of vascular cells. Rostaporfin is a monoclonal antibody that binds to the mitochondrial cytochrome P450, inhibiting its activity and decreasing oxygen consumption by mitochondria. This results in decreased cellular energy production and reduced cell proliferation in cancer cells, as well as other biological properties. The drug is also biocompatible with human tissue and can be used for the treatment of inflammatory bowel disease.</p>

<p>Inhibits cyclin-dependent kinase 4 and 6 (CDK4 and CDK6); antineoplastic</p>

<p>H-AQLNLATR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AQLNLATR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AQLNLATR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AQLNLATR-OH at the technical inquiry form on this page</p>

<p>H-SYGVTVWEL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-SYGVTVWEL-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-SYGVTVWEL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-SYGVTVWEL-OH at the technical inquiry form on this page</p>

<p>RSV antibody was raised in mouse using fusion protein of RSV, types A and B as the immunogen.</p>

<p>Farnesoid X receptor agonist</p>