Antibiotics
Antibiotics are compounds designed to destroy or inhibit the growth of various microorganisms, playing a crucial role in treating infections and preventing the spread of diseases. This category offers a diverse range of active ingredients specifically for research in the biochemical field. These compounds are essential tools in studying bacterial mechanisms, resistance patterns, and the development of new therapeutic agents. Researchers can explore a wide variety of antibiotics to understand their effects, optimize their use, and develop novel treatments to combat emerging microbial threats. The availability of such a broad spectrum of antibiotics supports advanced research and innovation in microbiology and pharmaceutical sciences.
Subcategories of "Antibiotics"
- Macrolide Antibiotics(26 products)
- Steroidal Antibiotics(31 products)
- Tetracycline Antibiotics(20 products)
- β-Lactam Antibiotics(11 products)
Found 4097 products of "Antibiotics"
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Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only
CAS:<p>Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.</p>Formula:C20H44N4O18S2Purity:Min. 97.0 Area-%Molecular weight:692.71 g/molCefonicid
CAS:<p>Cefonicid is a semisynthetic cephalosporin antibiotic, which is derived from the naturally occurring compound cephalosporin C, obtained from the mold *Cephalosporium acremonium*. Its mode of action involves inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death, thereby exhibiting bactericidal activity.</p>Formula:C18H16N6O8S3Purity:Min. 95%Molecular weight:540.55 g/mol26-Oxofusidic acid
CAS:<p>26-Oxofusidic acid is a derivative of fusidic acid, which is a potent antibacterial compound originally isolated from the fungus Fusidium coccineum. This compound exhibits a unique mode of action by inhibiting bacterial protein synthesis through interference with the elongation factor G (EF-G), a critical component in the translocation step of translation. By targeting this specific aspect of bacterial metabolism, 26-Oxofusidic acid effectively disrupts the growth of gram-positive bacteria, making it an invaluable tool in combating resistant bacterial strains.</p>Formula:C31H46O7Purity:Min. 95%Molecular weight:530.69 g/molTunicamycin
CAS:<p>Inhibitor of N-glycosylation in eukaryotes</p>Formula:C37H60N4O16Purity:Min. 95%Color and Shape:PowderMolecular weight:816.89Vancomycin aglycon
CAS:<p>Vancomycin aglycon is a glycopeptide antibiotic, which is a derivative of vancomycin. It is sourced from the fermentation products of certain Amycolatopsis species, a genus of actinobacteria. The mode of action of vancomycin aglycon involves the inhibition of bacterial cell wall synthesis. It specifically binds to the D-Ala-D-Ala terminus of nascent peptidoglycan chains, thereby preventing the cross-linking that is crucial for maintaining cell wall integrity.</p>Formula:C53H52Cl2N8O17Purity:Min. 95%Molecular weight:1,143.93 g/molVirginiamycin - Complex of M1+S1
CAS:<p>Virginiamycin - Complex of M1+S1 is an antibiotic compound, which is derived from the actinobacterium Streptomyces virginiae. It functions through the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby obstructing peptide bond formation and impeding microbial growth. The complex is composed of two major components: Virginiamycin M1 and Virginiamycin S1, which synergistically enhance antimicrobial efficacy.</p>Formula:C71H84N10O17Purity:Min. 95%Molecular weight:1,349.48 g/molN-Biotinyl-12-aminododecanoyltobramycin amide
CAS:<p>N-Biotinyl-12-aminododecanoyltobramycin amide is a synthetic bioconjugate, which is derived from the aminoglycoside antibiotic tobramycin. This compound is chemically modified by the addition of a biotin moiety linked through a 12-aminododecanoyl spacer. The source of this product is rooted in the conjugation of biotin to tobramycin, allowing for targeted delivery and potential hybrid applications in both therapeutic and diagnostic fields.</p>Formula:C40H74N8O12SPurity:Min. 95%Molecular weight:891.13 g/molTigemonam
CAS:<p>Tigemonam is a synthetic beta-lactam antibiotic, which is derived from chemical synthesis processes. This compound operates by inhibiting bacterial cell wall synthesis, specifically targeting the penicillin-binding proteins (PBPs). The disruption of the cell wall synthesis ultimately leads to cell lysis and death of the bacteria, making it effective primarily against gram-negative bacterial infections.</p>Formula:C12H15N5O9S2Purity:Min. 95%Molecular weight:437.41 g/molArbekacin sulfate
CAS:<p>Inhibitor of DNA replication; aminoglycoside class</p>Formula:C22H44N6O10·xH2SO4Purity:Min. 95%Color and Shape:White PowderMolecular weight:650.7 g/molPiericidin A
CAS:<p>Piericidin A is a microbial metabolite, specifically a type of polyketide, which is derived from the bacterium of the genus Streptomyces. This compound acts as an electron transport chain inhibitor by specifically binding to the ubiquinone binding site of complex I (NADH:ubiquinone oxidoreductase) in mitochondria. This mode of action results in the disruption of ATP production through oxidative phosphorylation.</p>Formula:C25H37NO4Purity:Min. 95%Molecular weight:415.57 g/molNarasin
CAS:<p>Narasin is an ionophore antibiotic, which is a fermentation product derived from certain strains of the bacterium *Streptomyces aureofaciens*. It functions by disrupting the ion gradients across cell membranes, specifically facilitating the transport of sodium and potassium ions. This action interferes with the energy metabolism of certain pathogenic microorganisms, rendering them unable to proliferate effectively.</p>Formula:C43H72O11Purity:Min. 95%Molecular weight:765.03 g/molPristinamycin IA
CAS:<p>Pristinamycin IA is a streptogramin antibiotic, which is a natural product derived from the bacterium *Streptomyces pristinaespiralis*. It operates by inhibiting bacterial protein synthesis through the disruption of ribosomal function, specifically targeting the 50S ribosomal subunit. This mode of action is effective in halting bacterial growth, making it particularly significant in combating resistant strains.</p>Formula:C45H54N8O10Purity:Min. 95%Molecular weight:866.96 g/molKanamycin A Related Compound 1
CAS:<p>Kanamycin A Related Compound 1 is an analytical reference standard, which is derived from aminoglycoside antibiotics. Its source stems from the chemical structures related to the aminoglycoside class, primarily used to ensure precise identification and quantification of kanamycin residues or impurities in pharmaceutical formulations. The mode of action of Kanamycin A Related Compound 1 involves serving as a comparator or reference point in chromatographic and spectroscopic methods, facilitating accurate analysis by providing a consistent baseline for research laboratories.</p>Formula:C12H25N3O7Purity:Min. 95%Molecular weight:323.34 g/molErythromycylamine
CAS:<p>Erythromycylamine is a semisynthetic antibiotic, which is derived from the parent compound erythromycin. This compound is sourced from the fermentation product of the bacterium *Saccharopolyspora erythraea*. Erythromycylamine acts by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit, which ultimately leads to the disruption of bacterial cell growth and replication.</p>Formula:C37H70N2O12Purity:Min. 95%Molecular weight:734.96 g/molAclacinomycin HCl
CAS:<p>Aclacinomycin HCl is a cytotoxic antibiotic that inhibits the growth of tumor cells. It has been shown to induce apoptosis in human leukemia cells by altering the transmembrane potential and inhibiting cell proliferation. Aclacinomycin HCl also induces DNA damage response, which leads to caspase activities and cell death. This drug is highly selective for tumor cells, with no effect on normal cells. It has been shown to be effective against primary liver cancer in animal models, as well as developmental disorders such as autism spectrum disorder (ASD).</p>Formula:C42H53NO15·HClPurity:Min. 95%Color and Shape:Orange PowderMolecular weight:848.33 g/molRifamdin
CAS:<p>Rifamdin is an antibiotic, which is a chemical substance derived from the source compound rifampicin. Its mode of action involves the inhibition of bacterial DNA-dependent RNA polymerase, which effectively suppresses bacterial RNA synthesis, leading to cell death. This mechanism primarily targets Mycobacterium tuberculosis, the causative agent of tuberculosis.</p>Formula:C46H64N4O12Purity:Min. 95%Molecular weight:865.02 g/molAminosidine
CAS:<p>Aminosidine is a nucleoside analogue that inhibits the HIV-1 reverse transcriptase and the integrase, which are enzymes involved in viral DNA synthesis. Aminosidine is active against Leishmania spp., but not against bacteria. Aminosidine has been shown to be effective in experimental models of human bowel disease and in patients with inflammatory bowel disease. It was also found to be active against wild-type strains of human immunodeficiency virus type 1, but not resistant mutants. The mechanism of action is the inhibition of cellular mitochondrial membrane potential.</p>Purity:Min. 95%PNU 142300
CAS:<p>PNU 142300 is a non-peptidyl anticoagulant, which is a synthetically derived small molecule. This compound is sourced from advanced chemical synthesis techniques that focus on mimicking biological activity through non-biological materials. PNU 142300 acts by specifically inhibiting factor Xa, a crucial enzyme in the coagulation cascade responsible for the conversion of prothrombin to thrombin. By targeting this enzyme, it effectively prevents the formation of blood clots, thereby exhibiting potent anticoagulant properties.</p>Formula:C16H20FN3O6Purity:Min. 95%Molecular weight:369.35 g/molErythromycin F
CAS:<p>Erythromycin F is an antibiotic, which is a naturally derived product obtained from the bacterium *Streptomyces erythreus*. It operates by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit. This binding effectively blocks the translocation steps in protein elongation, thus preventing the growth and multiplication of susceptible bacteria.</p>Formula:C37H67NO14Purity:Min. 95%Molecular weight:749.93 g/molIclaprim
CAS:<p>Iclaprim is an antibiotic, which is a synthetic diaminopyrimidine antimicrobial agent with a specific mechanism of action. It works by selectively inhibiting bacterial dihydrofolate reductase, a crucial enzyme in the bacterial folate synthesis pathway. This inhibition prevents the production of tetrahydrofolate, ultimately disrupting DNA, RNA, and protein synthesis in susceptible bacterial cells.</p>Formula:C19H22N4O3Purity:Min. 95%Molecular weight:354.4 g/molCefteram
CAS:<p>Cefteram is a third-generation cephalosporin antibiotic, which is synthesized through chemical processes starting from cephalosporin C, a compound derived from the fungus Acremonium. As a cephalosporin, it functions by inhibiting bacterial cell wall synthesis. This is achieved through the binding to penicillin-binding proteins (PBPs), which are critical in the formation of the bacterial cell wall. By disrupting this process, Cefteram leads to the lysis and death of the bacteria.</p>Formula:C16H17N9O5S2Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:479.5 g/mol8-Fluoro erythromycin
CAS:<p>8-Fluoro erythromycin is a synthetic derivative of the macrolide antibiotic erythromycin. It is derived from the fermentation of *Streptomyces erythraeus*, a species known for producing erythromycin, which is chemically modified to include a fluorine atom at the eighth position. This modification enhances its pharmacokinetic properties, improving its stability and bioavailability compared to the parent compound.</p>Formula:C37H66FNO13Purity:Min. 95%Molecular weight:751.92 g/molDicloxacillin sodium salt monohydrate
CAS:<p>Dicloxacillin sodium salt monohydrate is a beta-lactam antibiotic with action on bacterial cell wall synthesis and is used for treating infections caused by penicillinase-producing bacteria.</p>Formula:C19H16Cl2N3NaO5S·H2OPurity:Min. 95%Color and Shape:White PowderMolecular weight:510.32 g/molLysostaphin, from staphylococcus staphylolyticus
CAS:<p>Lysostaphin, from Staphylococcus staphylolyticus is a zinc metalloenzyme with action on bacterial cell walls by cleaving polyglycine cross-links and is used for treating staphylococcal infections and in research applications.</p>Purity:Min. 95%Color and Shape:PowderNafcillin sodium
CAS:<p>Nafcillin sodium is a beta-lactam antibiotic, which is a semisynthetic derivative of the organic compound penicillin. It is specifically engineered to be resistant to the inactivation by penicillinase enzymes produced by certain bacteria. This feature allows it to remain effective against a range of penicillinase-producing staphylococcal infections.</p>Formula:C21H21N2NaO5SPurity:Min. 95%Color and Shape:PowderMolecular weight:436.46 g/molTetracycline hydrochloride, Antibiotic for Culture Media Use Only
CAS:<p>Tetracycline hydrochloride is a broad-spectrum antibiotic and is an electron transfer agent. It has been shown to be effective against bacterial infections in humans and has been used in cultures for the prevention of bacterial contamination. As an electron transfer agent, it is used in electron microscopy to study the surface of biological cells. Tetracycline hydrochloride enters bacterial cells by diffusion and interacts with the cytoplasmic membrane, where it induces a redox reaction that leads to cell death. The efficacy of tetracycline hydrochloride in treating candida albicans (yeast) was studied using in-vitro activity and showed that carboxymethyl chitosan nanoparticles were able to enhance the treatment efficiency.</p>Formula:C22H25ClN2O8Purity:Min. 88.0 Area-%Molecular weight:480.90 g/molRef: 3D-T-1961
1kgTo inquire5kgTo inquire10kgTo inquire25kgTo inquire2500gTo inquire-Unit-kgkgTo inquireThiostrepton
CAS:<p>Thiostrepton is a thiopeptide antibiotic with action on bacterial protein synthesis by binding to the ribosome and is used for treating bacterial infections in veterinary medicine and research applications.</p>Formula:C72H85N19O18S5Purity:Min. 95%Color and Shape:White To Light (Or Pale) Yellow SolidMolecular weight:1,664.89 g/molAspterric acid
CAS:<p>Plant growth regulator</p>Formula:C15H22O4Purity:Min. 95%Molecular weight:266.33 g/molSarecycline
CAS:<p>Sarecycline is a tetracycline-class antibiotic, which is derived from naturally occurring tetracycline antibiotics. Its mode of action involves inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to nascent peptide chains. This specific mechanism disrupts bacterial growth, making Sarecycline effective against certain strains of bacteria implicated in dermatological conditions.</p>Formula:C24H29N3O8Purity:Min. 95 Area-%Molecular weight:487.5 g/molPotassium clavulanate - 1:1 mixture with cellulose, Antibiotic for Culture Media Use Only
CAS:<p>Potassium clavulanate is a beta-lactamase inhibitor and an antibacterial agent. The presence of potassium clavulanate in culture media inhibits the activity of beta-lactamases, which are enzymes that confer resistance to penicillin and other beta-lactam antibiotics. It also has been shown to be active against bacterial infections such as tuberculosis, sepsis, and pneumonia, where it can inhibit the growth of bacteria by interfering with their ability to form cell walls.</p>Formula:C8H8KNO5Purity:Min. 95.0 Area-%Molecular weight:237.25 g/molCloxacillin benzathine
CAS:<p>Cloxacillin benzathine is a beta-lactam antibiotic, which is synthesized from Penicillium fungi-derived penicillins. It acts by inhibiting bacterial cell wall synthesis. The mechanism involves the irreversible inhibition of penicillin-binding proteins (PBPs). This disruption in the bacterial cell wall structure ultimately leads to cell lysis and death.</p>Formula:C54H56Cl2N8O10S2Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:1,112.11 g/molTri-O-benzyl FR 900098
CAS:<p>Tri-O-benzyl FR 900098 is a chemical compound, often referenced in biochemical research contexts. It is a synthetic derivative that originates from complex chemical synthesis, involving multiple benzylation steps to modify the original molecular framework. This structural transformation lends the compound unique chemical properties.</p>Formula:C26H30NO5PPurity:Min. 95%Molecular weight:467.49 g/mol25-O-Deacetyl rifabutin
CAS:<p>25-O-Deacetyl rifabutin is an antibiotic derivative, which is sourced from the semi-synthetic modification of rifabutin, a compound originally derived from the fermentation of the bacterium Amycolatopsis mediterranei. This derivative works by inhibiting bacterial RNA synthesis. It achieves this by specifically targeting the DNA-dependent RNA polymerase enzyme, which is essential for bacterial transcription. The mechanism involves binding to the beta-subunit of the polymerase, thereby blocking the elongation of the RNA chain, which ultimately leads to the death of the bacterial cell.</p>Formula:C44H60N4O10Purity:Min. 95%Color and Shape:Purple PowderMolecular weight:804.97 g/molent NAP 226-90
CAS:<p>ent NAP 226-90 is an organic compound functioning as an antibacterial agent, which is derived from a biologically active natural product. Its mode of action involves the inhibition of essential bacterial enzymes, leading to the disruption of cellular processes within susceptible microorganisms. This compound is particularly effective against a broad spectrum of gram-positive bacteria, making it valuable in medical microbiology research for understanding bacterial resistance mechanisms.</p>Formula:C10H15NOPurity:Min. 95%Molecular weight:165.23 g/molSulbenicillin
CAS:<p>Sulbenicillin is a semi-synthetic penicillin antibiotic, which is derived from 6-aminopenicillanic acid, a natural precursor in the biosynthesis of penicillins. With its beta-lactam structure, Sulbenicillin disrupts bacterial cell wall synthesis by inhibiting penicillin-binding proteins, which are essential enzymes in the cross-linking of peptidoglycan layers. This disruption compromises the structural integrity of the bacterial cell wall, resulting in cell lysis and death, particularly in Gram-negative bacteria.</p>Formula:C16H18N2O7S2Purity:Min. 95%Molecular weight:414.46 g/molNeomycin B
CAS:<p>Neomycin B is an aminoglycoside antibiotic, which is derived from the bacterium *Streptomyces fradiae*. It exerts its antibacterial effects by binding to the 30S subunit of bacterial ribosomes, leading to the inhibition of protein synthesis. This binding disrupts the translation process, thereby preventing the growth and proliferation of bacteria. Neomycin B is effective against a wide range of Gram-negative and some Gram-positive bacteria, making it a valuable tool in both medical and research settings.</p>Formula:C23H46N6O13Purity:Min. 95%Molecular weight:614.64 g/molClindamycin
CAS:<p>Inhibitor of protein synthesis; lincosamide class</p>Formula:C18H33ClN2O5SPurity:Min. 95%Molecular weight:424.98 g/molTrovafloxacin mesylate
CAS:<p>Trovafloxacin mesylate is a synthetic antibiotic belonging to the fluoroquinolone class, which is derived from chemical synthesis processes rather than natural sources. The mode of action of trovafloxacin mesylate involves the inhibition of bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication, repair, and transcription within the bacterial cell. By inhibiting these enzymes, trovafloxacin mesylate disrupts bacterial DNA processes, leading to cell death and exerting its antibacterial effects.</p>Formula:C21H19F3N4O6SPurity:Min. 95%Molecular weight:512.46 g/mol2'-O-Acetylspiramycin I
CAS:<p>2'-O-Acetylspiramycin I is a semi-synthetic derivative of spiramycin, which is a macrolide antibiotic originally sourced from the bacterium *Streptomyces ambofaciens*. The modification involves the acetylation at the 2'-hydroxyl group of spiramycin, enhancing certain pharmacokinetic properties.</p>Formula:C45H76N2O15Purity:Min. 95%Molecular weight:885.09 g/mol(10E)-10,11-Didehydro-11-deoxy-6-O-methylerythromycin
CAS:<p>(E)-10,11-Didehydro-11-deoxy-6-O-methylerythromycin is a semisynthetic macrolide antibiotic, which is derived from erythromycin, a natural product obtained from the bacterium *Saccharopolyspora erythraea*. This compound functions as an inhibitor of protein synthesis by binding to the 50S ribosomal subunit of bacteria, thus preventing the growth and proliferation of susceptible bacterial strains. The alteration in its chemical structure, notably the methylation at the 6-O position, enhances its stability and improves its pharmacokinetic profile compared to the parent compound, erythromycin.</p>Formula:C38H67NO12Purity:Min. 95%Molecular weight:729.94 g/molClindamycin 4-phosphate
CAS:<p>Clindamycin 4-phosphate is a semi-synthetic antibiotic, which is a derivative of the natural antibiotic lincomycin. It is specifically synthesized from Streptomyces lincolnensis cultures. The mode of action of Clindamycin 4-phosphate involves inhibiting bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome, thus preventing peptide chain elongation and subsequent bacterial growth.</p>Formula:C18H34ClN2O8PSPurity:Min. 95%Molecular weight:504.96 g/molVancomycin CDP-1
CAS:<p>Vancomycin CDP-1 is a degradation product of vancomycin with no direct therapeutic action but used in research for analytical method development and validation.</p>Formula:C66H74Cl2N8O25Purity:Min. 95%Color and Shape:PowderMolecular weight:1,450.24 g/molChaetoglobosin A - From chaetomium globosum
CAS:<p>Chaetoglobosin A is a mycotoxin, which is a secondary metabolite produced by the fungus Chaetomium globosum. This compound exhibits its mode of action by disrupting the cytoskeletal elements within cells, primarily affecting actin polymerization. This interference leads to alterations in cell morphology and can induce apoptosis in certain cell lines.</p>Formula:C32H36N2O5Purity:Min. 95%Molecular weight:528.64 g/molOligomycin B
CAS:<p>Oligomycin B is an antibiotic compound, which is derived from Streptomyces species. It is an inhibitor of the mitochondrial ATP synthase complex, specifically targeting the F₀ subunit of ATP synthase. This action obstructs the proton channel, preventing the flow of protons across the mitochondrial membrane. As a result, Oligomycin B effectively halts ATP synthesis by oxidative phosphorylation, which is crucial for the survival of aerobic organisms.</p>Formula:C45H72O12Purity:Min. 95%Color and Shape:PowderMolecular weight:805.05 g/mol7-epi-Clindamycin
CAS:<p>7-epi-Clindamycin is a clindamycin derivative, which is a semisynthetic antibiotic derived from the bacterium *Streptomyces lincolnensis*. Its mode of action involves binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis. This results in the suppression of bacterial growth, making it effective against certain Gram-positive bacteria and anaerobic species.</p>Formula:C18H34Cl2N2O5SPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:461.44 g/molCefadroxil monohydrate, Antibiotic for Culture Media Use Only
CAS:<p>Cefadroxil is a broad-spectrum bactericidal antibiotic that belongs to the cephalosporin family. It is a semi-synthetic penicillin and inhibits bacterial cell wall synthesis through binding to one or more of the penicillin-binding proteins (PBPs). Cefadroxil monohydrate is used as an antibiotic for culture media and has been proven to be effective against methicillin-resistant Staphylococcus aureus (MRSA). In addition, the drug has been shown to have no significant effect on blood tests or microscopic studies.</p>Formula:C16H19N3O6SPurity:Min. 97.0 Area-%Molecular weight:381.40 g/molN'-Desmethyl azithromycin
CAS:<p>N'-Desmethyl azithromycin is a semi-synthetic derivative antibiotic, which is derived from the chemical modification of azithromycin, a macrolide antibiotic sourced originally from the bacterium *Streptomyces erythreus*. It functions primarily by inhibiting bacterial protein synthesis, binding specifically to the 50S ribosomal subunit, which results in the prevention of transpeptidation and translocation processes during translation. This action effectively halts bacterial growth, rendering it bacteriostatic.</p>Formula:C37H70N2O12Purity:Min. 95%Molecular weight:734.96 g/molN-Demethyl rifampin
CAS:<p>N-Demethyl rifampin is a metabolite of rifampin, which is a natural product derivative. Rifampin itself is a well-known antibiotic derived from the bacterium *Amycolatopsis rifamycinica*. N-Demethyl rifampin is formed through the metabolic process where rifampin undergoes demethylation. This transformation occurs primarily in the liver, mediated by the cytochrome P450 enzyme system.</p>Formula:C42H56N4O12Purity:Min. 95%Molecular weight:808.91 g/mol
