Antibiotics

<p>Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert</p>

<p>Bestatin (Ubenimex) competitively inhibits many aminopeptidases. Bestatin is a microbial metabolite and dipeptide with immunomodulatory and antitumor effects.</p>

CORM-401 is an oxidant-sensitive CO-releasing molecule. It can be used in oxidative stress-mediated pathologies and the research of inflammatory.

Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent.

Tirilazad mesylate (U 74006F) is a lipid peroxidation inhibitor with antiviral activity.Tirilazad mesylate is used in the study of neurological disorders.

3-(Trifluoromethyl)cinnamic acid (3-(3-(Trifluoromethyl)phenyl)acrylic acid) can be used to study drug-resistant bacterial infections.

<p>Applications Nisin Z Hydrochloride is a peptide antibiotic synthesized by Lactococcus lactis. Nisin Z interacts with lipid II, a lipid component of cell wall, to form pores in the plasma membrane.<br>References Kuipers, O. P., et al.: J. Biol. Chem. 270, 27299 (1995); Breukink, E., et al.: Science 286, 2361 (1999); Breukink, E., et al.: Biochemistry 36, 6968 (1997)<br></p>

<p>Applications Surfactin is a lipopeptide antibiotic and biosurfactant.<br></p>

<p>Difloxacin is a fluoroquinolone antibiotic, which is a synthetic compound derived from chemical synthesis methods. Its source involves complex organic chemistry that modifies the quinolone backbone to enhance its antibacterial properties. Difloxacin functions by inhibiting bacterial DNA gyrase and topoisomerase IV, which are critical enzymes involved in DNA replication, transcription, and repair. This inhibition leads to the prevention of cellular division and ultimately results in bacterial cell death.</p>

<p>Inhibitor of prokaryotic DNA gyrase, eukaryotic DNA topoisomerase and HSP90</p>

<p>Inhibitor of protein synthesis; aminocyclitol class</p>

<p>Inhibitor of cell-wall synthesis; carbapenem class</p>

<p>Penicillin G sodium is a natural penicillin antibiotic with action on bacterial cell wall synthesis and is used for treating bacterial infections such as pneumonia, gonorrhea, and anthrax.</p>

<p>Aminoglycoside antibiotic; inhibits protein synthesis by inducing miscoding</p>

<p>Nalidixic acid sodium salt is a sodium salt form of nalidixic acid with similar action and applications as nalidixic acid.</p>

<p>Cephradine is a first-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating bacterial infections like urinary tract infections, respiratory infections, and skin infections.</p>

<p>Herbicidin E is a potent herbicidal compound, derived from blue-green algae, with a biochemical mode of action focused on inhibiting photosynthetic electron transport. It effectively disrupts the photosynthetic process by binding to specific sites within the chloroplasts of target plants, impairing their ability to convert light energy into chemical energy. This leads to a depletion of essential energy reserves, resulting in the controlled demise of the plant.</p>

<p>Membrane-disrupting agent</p>

<p>5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate is an antibacterial compound with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. It is active against strains resistant to other antibiotics, such as, tetracycline and penicillin. 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate has been shown to be effective in vitro against Campylobacter jejuni - the most common cause of bacterial gastroenteritis in humans. The compound also inhibits the growth cycle of Campylobacter jejuni by arresting the cells at the G1 phase. The molecule has been shown to inhibit DNA synthesis in E. coli and S. typhimurium with IC50 values of 1 ÎŒM and 0.8 ÎŒM respectively. This molecule has been tested for its surface active properties and it can be used as an additive in personal care products for improved wetting and spreading on surfaces. The compound is also researched for its antifungal efficacy against Candida albicans by inhibiting the growth cycle of the fungus.</p>