Heterocycles with Nitrogen (N)

<p>Applications 4-Oxo-2,2,6,6-tetramethylpiperidine-d16;1-15N-1-oxyl (CAS# 80404-14-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-(4,5-dihydro-1H-imidazol-2-yl)pyridine (cas# 7471-05-8) is a useful research chemical.<br></p>

<p>Applications (4S)​- 5,​5-​Dimethyl-​2-​[[[(5-​methyl-​3-​phenyl-​4-​isoxazolyl)​carbonyl]​amino]​methyl]​-4-​thiazolidinecarboxyl​ic acid is a useful reactant.<br></p>

<p>Applications 1-Pyridin-2-yl-propan-2-one is an antimicrobial bioactive compound extracted from Lactarius vellereus fermenting liquor.<br>References Ji, H., et al.: Beijing Linye Daxue Xuebao, 30, 92 (2008); Song, R., et al.: From Faming Zhuanli Shenqing (2008), CN 101230368 A 20080730;<br></p>

<p>Applications (3E)-4-(5-Ethoxy-3-pyridinyl)-3-buten-1-ol is an intermediate in the synthesis of TC 2559 Fumarate (T012005), which is a partial agonist for AChR α4β2.<br></p>

<p>Applications An intermediate in the preparation of serotonin 5-HT2a receptor antagonists<br>References Ullrich, T., et al.: Bioorg. Med. Chem., 8, 2427 (2000),<br></p>

<p>Applications A new reagent that is a naphtalene analog of 4-(4'-N,N-Dimethylaminophenyl)urazole (D451750).<br>References Shams, E., et al.: Analitical Sci., 2002, 18, 993 ;<br></p>

<p>Applications 4-BROMO-2-PYRIDINECARBOXAMIDE (cas# 62150-46-3) is a useful research chemical.<br></p>

<p>Applications 2,4-Diamino-6-hydroxypyrimidine-15N3 (cas# 1638736-04-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Hydroxy-3H-imidazole-4-carboxamide (cas# 56973-26-3) is a compound useful in organic synthesis.<br></p>

<p>Applications An intermediate in the production of labelled Enrofloxacin.<br>References Chao, Q., et al.: J. Med. Chem., 52, 7808 (2009), Bebbington, D., et al.: Bioorg. Med. Chem. Lett., 19, 3586 (2009),<br></p>

<p>Applications 6-Methyl-3-pyridinol is a reagent in the preparation of anilino(pyridyl)quinolinecarbonitriles which has Src kinase inhibitiion and antitumor properties.<br>References Zhang, N., et al.: Bioorg. Med. Chem. Lett., 19, 5071 (2009); Blume-Jensen, P., et al.: Nature, 411, 355 (2001)<br></p>

<p>Applications 1-PHENYL-3-(PIPERIDIN-1-YL)PROPAN-1-ONE HCL (cas# 886-06-6) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications [1,2,4]Triazolo[4,3-a]pyridine-3-thiol (cas# 6952-68-7) is a useful research chemical.<br></p>

<p>Applications 5-Methyl-pyrazine-2-carboxylic Acid (cas# 5521-55-1) is a compound useful in organic synthesis.<br></p>

<p>Impurity Irbesartan Bromo N2-Trityl Impurity<br>Stability Moisture Sensitive<br>Applications An intermediate in the synthesis of Losartan and Valsartan.<br></p>

<p>Applications L-threo-α-Phenyl-2-piperidineacetamide-d10 is an labelled intermediate in the synthesis of labelled L-threo-Ritalinic Acid (R533132).<br>References Chavan, A.B. et al.: Otg. Proc. Res. Dev., 14, 1473 (2010);<br></p>

<p>Applications 2,4-Dimethoxypyrimidine, is a versatile building block used in synthesis of various chemical compounds, such as derivatives of Cytidine (C998300).<br>References Kammerer, B., et al.: Anal. Biol. Chem., 382, 1017 (2005); Strong, L. and Matsunaga, H.: J. Surg. Oncol., 4, 528 (1972)<br></p>

<p>Applications (S)-tert-butyl 4-aminoazepane-1-carboxylate (cas# 878630-84-3) is a useful research chemical.<br></p>

<p>Applications 1,1'-Ethylenedipiperazine Hydrochloride Salt is the salt form of 1,1'-Ethylenedipiperazine, which is used in the synthetic preparation of novel series of bisintercalating DNA-binding piperazine-linked bisanthrapyrazoles as anticancer agents.<br>References Zhang, R.; et al.: Bioorganic Med. Chem., 19, 7023 (2011)<br></p>

<p>Applications [5-(pyridin-2-yl)-1H-imidazol-2-yl]methanamine trihydrochloride (cas# 2060007-34-1) is a useful research chemical.<br></p>

<p>Applications 3-[3-(aminomethyl)phenyl]-1,3-oxazolidin-2-one (cas# 952391-73-0) is a useful research chemical.<br></p>

<p>Applications A chiral fluoro-pyridine derivative used in the preparation of dihydropyrrolopyrimidinone derivatives for use as MARK inhibitors.<br></p>

<p>Applications 2-(Difluoromethoxy)pyridin-4-amine (cas# 1211587-46-0) is a useful research chemical.<br></p>

<p>Applications 5-Nitro-2-(propylthio)pyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)<br></p>

<p>Applications 2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil(C175580), an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.<br>References Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)<br></p>

<p>Applications 5-Fluoro-2-pyridinesulfonyl Chloride acts as a reagent for the synthesis of potential TK inhibitors with improved pharmacokinectics for resistant CML.<br>References Ali, Ahmed M., et al.: ChemMedChem, 11, 850 (2016)<br></p>

<p>Applications Methyl 6-aminopyridazine-3-carboxylate<br></p>

<p>Applications 6-Bromo-5-methyl-3h-imidazo[4,5-b]pyridine<br></p>

<p>Applications 1-(4-Chlorophenyl)-1,2-dihydro-3H-pyrazol-3-one is also used in the synthesis of antifungal, oxazolidinon-based strobilurin analogues. Also used in the preparation of heterologous haptens for the synthesis of high-affinity anti-pyraclostrobin antibody generation.<br>References Li, Y. et al.: Bull. Kor. Chem. Soc., 31, 3341 (2010); Mercader, J. et al.: Org. Biomol. Chem., 9, 1443 (2011);<br></p>

<p>Applications 7-Chloro-N-[1-(methylsulfonyl)-4-piperidinyl]-4-quinazolinamine, is a building block used in chemical synthesis.<br></p>

<p>Applications 1-Phenyl-pyrazole 4-pyruvic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil(C175580), an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.<br>References Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)<br></p>

<p>Applications [1,2,4]Triazolo[1,5-a]pyridin-8-ol can be used to prepare aminopyridine derivatives as glucokinase activators useful to treat diseases.<br>References Aicher, T. D., et al.: PCT Int. Appl., 145, (2008);<br></p>

<p>Applications 3-Hydroxypicolinic acid<br></p>

<p>Applications Methyl 4-Methylpyrrole-2-carboxylate is a useful reagent for preparation of (E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives, a novel class of glycine site antagonists.<br>References Balsamini, C., et al.: J. Med. Chem., 41, 808 (1998);<br></p>

<p>Applications 6-NITROPIPERONYL ALCOHOL (cas# 15341-08-9) is a useful research chemical.<br></p>

<p>Applications Tris(4-pyridyl)-s-triazine is used in the preparation of metal-metallite coordination polymers as well as porphyrin prisms.<br>References Youm, K. et al.: Chem. Comm., 29, 3375 (2008); Li, M. et al.: CrystEngComm., 15, 1225 (2013);<br></p>

<p>Applications 2,5,6-Triaminopyrimidin-4(1H)-one sulphate (cas# 39267-74-8) is a useful research chemical.<br></p>

<p>Applications 4,5-Dimethyl-4H-1,2,4-triazole-3-acetic Acid is a useful synthetic intermediate.<br></p>

<p>Applications imidazo[1,2-a]pyridin-7-amine hydrobromide (cas# 1630906-80-7) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive, Hygroscopic<br>Applications 1,2-dimethyl-1H-imidazole-4-sulfonyl chloride (cas# 137049-02-6) is a useful research chemical.<br></p>

<p>Applications 2-Acetyl-3,4,5,6-tetrahydropyridine-d4 Hydrochloride, is the labeled analogue of 2-Acetyl-3,4,5,6-tetrahydropyridine Hydrochloride (A188500), the most important bread flavor component.<br>References Buttery, R.G., et al.: J. Agric. Food Chem., 43, 1878 (1995),<br></p>

<p>Applications 2,5-Diamino-4,6-dichloropyrimidine is a useful reagent for the preparation of Abacavir impurities, carbocyclic and hexenopyranosy nucleosides.<br>References Satyanarayana, G. V., et al.: Pharma Chemica, 7, 90 (2015)<br></p>

<p>Applications 2,4-difluoro-5-(2-oxoimidazolidin-1-yl)benzoic acid (cas# 1178351-23-9) is a useful research chemical.<br></p>

<p>Applications 2,6-Dibromo-3-fluoropyridine is a useful reagent for making GLP-1 receptor agonists.<br>References Aspnes, G. E., et al.: PCT Int. Appl. (2019), WO 2019239371 A1<br></p>

<p>Please enquire for more information about Ethyl 6-methyl-2-thioxo-4-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-Methyl-2-(piperazin-1-ylcarbonyl)-1H-indole hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Bromopyridine-3-carboxaldehyde (6-BPAR) is a synthetic compound that binds to copper ions and has been shown to have inhibitory activities against trifluoroacetic acid, calcium carbonate, optical properties, and low energy. 6-BPAR also has an aldehyde group and hydroxamic acid group. This chemical can be used as a catalyst for the hydrogenation reduction of metal ions such as chloride or formyl groups.</p>

<p>Please enquire for more information about 1-(2-Benzyloxyethyl)piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3,5-Dimethylpyrazine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Chloro-2-nitropyridine is a chemical compound that has been shown to have anticancer activity. It is a structural analog of the nucleophilic piperazine, which can react with hydrogen fluoride in an electrophilic substitution reaction to form 3-chloro-2-nitropyridine oxide. The anticancer activity of this compound may be due to its ability to inhibit the growth of tumor cells by binding to the d4 receptor, inhibiting the production of inflammatory cytokines and growth factors. 3-Chloro-2-nitropyridine has also been shown to have antiinflammatory activities, which may be due to its inhibition of nitric oxide synthesis and 5'-lipoxygenase.</p>

<p>3,5-Dibromopyrazin-2-amine is a triethyl orthoformate derivative that reacts with formamide to form 3,5-dibromopyrazine. The reaction time is typically less than 10 minutes and the yield is high. The product can be stored in a dry, inert atmosphere for up to 3 months without degradation. The compound has been shown to inhibit cyclic nucleotide phosphodiesterase (PDE) enzymes and cancer cells in vitro.</p>

<p>Please enquire for more information about Methyl4-aminomethyl-1-boc-piperidine-4-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about S-Desmethyl-S-(2-hydroxy-2-methylpropyl) rosuvastatin calcium including the price, delivery time and more detailed product information at the technical inquiry form on this page