Building Blocks

<p>Versatile small molecule scaffold</p>

<p>BMS-986165 is a P-glycoprotein (P-gp) inhibitor that has been shown to reduce the absorption of ciclosporin, tacrolimus, and everolimus in vitro. BMS-986165 has an activity index of 100% and inhibits the inflammatory response by inhibiting the production of cytokines. It has been found to be effective for treating bowel diseases, such as ulcerative colitis and Crohn's disease. The drug also may be used for the treatment of autoimmune diseases, such as psoriasis or rheumatoid arthritis. BMS-986165 is administered orally and is rapidly absorbed. It is metabolized by CYP3A4 and excreted in urine as metabolites. END&gt;&gt; END&gt;&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>3-Ethynylbenzenesulfonamide is a synthetic, hydrophobic, antimicrobial compound that disrupts the cell membrane. It has been shown to be effective against both mammalian and microbial cells. The antimicrobial use of this compound is still under study, but it may provide an alternative to the current antibiotics. 3-Ethynylbenzenesulfonamide is amphipathic in nature and has an extremely large expansion ratio. This molecule is also hydrophobic, which may help with its ability to penetrate the cell membrane. Antimicrobial compounds are designed to inhibit or kill microorganisms such as bacteria or fungi by disrupting their cellular membranes. They work by interacting with specific targets on the surface of the target organism and producing a lethal effect on its function. 3-Ethynylbenzenesulfonamide interacts with proteins found on bacterial membranes called porins, resulting in a loss of osmotic stability and then permeability through the bilayer. This leads</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Bromo-PEG3-azide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromo-PEG3-azide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>2-Bromo-3-hydroxy-benzaldehyde is a nitrate that has been shown to have anti-cancer properties. It inhibits the growth of cancer cells by binding to bromodomains in their DNA, thereby preventing transcription and replication. 2-Bromo-3-hydroxy-benzaldehyde also inhibits the production of nitric oxide, which may lead to an inhibitory effect on tumour angiogenesis. The stereoisomers of this compound are used as precursors for the synthesis of ammonium nitrate, which is used as a fertilizer and explosive. 2-Bromo-3-hydroxy-benzaldehyde is also used in organic synthesis as a precursor for acetylation or halide reactions with palladium complexes or halides.</p>

<p>2-Bromocyclopentanone is an organic molecule that is used in the synthesis of epoxides. It is also a potential precursor for the synthesis of polymers, dyes, and pharmaceuticals. 2-Bromocyclopentanone has been shown to undergo photolysis when irradiated with ultraviolet light or through chemical reaction with acetonitrile. This product has two conformers with different rotational barriers and corresponding spectral properties. The two conformers can be distinguished by their ultraviolet spectra. The synthetic methods for 2-bromocyclopentanone involve halogenation followed by hydrolysis to yield bromoacetic acid, which is then converted to the desired product by acylation or alkylation.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methylthiazole-4-carboxaldehyde is an aldehyde that is the product of the condensation of 2,4-dibenzoylacetone and acetone in the presence of diazomethane. It has been used as a precursor to other compounds such as benzoyl chloride, glyoxal, and aldehydes. 2-Methylthiazole-4-carboxaldehyde can be synthesized using acetylation or nitration of thiols or with glyoxal or aldehyde. The reactivity of this compound is high and can be carried out in high yield.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-3-methoxypropanoic acid hydrochloride is a mitochondrial enzyme inhibitor that is used as a research tool to study protein synthesis. It binds to the cytochrome b2 subunit of the mitochondrial respiratory chain, inhibiting the oxidation of pyruvate and affecting the production of ATP. 2-Amino-3-methoxypropanoic acid hydrochloride has been shown to induce apoptosis in human liver cells by triggering caspase 3, which is an important enzyme in the apoptotic pathway. 2-Amino-3-methoxypropanoic acid hydrochloride also has a number of chemical properties that make it useful for analytical chemistry. For example, 2-amino-3-methoxypropanoic acid hydrochloride can be used to measure carboxylic acids, acetylation reactions, hydrogen bonds and hydroxyl groups. It can also be used as a nucle</p>

<p>Versatile small molecule scaffold</p>

<p>3,3²-Dithiobis(propionitrile) is a molecule that includes sodium hydroxide solution and acrylonitrile. It reacts with 3-mercaptopropionic acid to form sodium hydrogen ester compounds. This reaction takes place in a sealed container and is catalyzed by carbonic and hydrochloric acids. The product of this reaction is 3-thiocyanatoacrylic acid.</p>

<p>4-(2-Bromoethyl)morpholine hydrobromide is a solvent that is used as an agent in the production of other chemicals. It is a colorless, crystalline solid with a constant melting point of 130 to 131 degrees Celsius. 4-(2-Bromoethyl)morpholine hydrobromide is soluble in acetone, ethanol, ether, and water. This chemical has been shown to be toxic and should be handled with care.</p>

<p>Tadalafil is a synthetic drug that is used as a treatment for erectile dysfunction. It works by inhibiting the PDE5 enzyme, which is responsible for breaking down cGMP. Tadalafil has been shown to be effective in the treatment of male erectile dysfunction and pulmonary hypertension, with few side effects. This drug is taken orally, with a meal or without one, and can be administered with or without food. To improve absorption, tadalafil should be taken at least 30 minutes before sexual activity. The dosage of tadalafil ranges from 2.5 to 20 mg, and it should not exceed 40 mg per day.</p>

<p>Please enquire for more information about 2,2,2-Trifluoroethanesulfinyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol is a congener that belongs to the class of monoclonal antibodies. It is a degradable and photophysical agent that enhances ionotropic gelation and proton exchange in an acidic environment. This agent has been shown to react with nucleophilic groups, such as amines and thiols, and has fluorescence properties that are sensitive to pH changes. The reactive nature of this compound makes it useful for the localization of model proteins in analytical chemistry experiments.</p>

<p>4-Amino-2,6-dimethoxypyrimidine is an organic compound that has been shown to be a methylating agent. It reacts with the hydrogen chloride present in seawater to form methyl chloride and hydrochloric acid. 4-Amino-2,6-dimethoxypyrimidine also interacts with hydrogen bonds and forms hydrogen bonds with other molecules. The molecular modeling study revealed that this compound is soluble in mineral acids such as sulfuric acid and hydrochloric acid. The solubility data also showed that 4-amino-2,6-dimethoxypyrimidine is soluble in water but not in chlorinated water. This drug has shown significant antifungal activity against Cryptococcus neoformans and Gram-negative organisms such as Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter</p>

<p>Versatile small molecule scaffold</p>

<p>N-(4-Aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide is an environmental and industrial chemical that is used as a formate, benzoate, and methyl benzoate intermediate. It reacts with nitric acid to form N-(4-aminophenyl)-N-methyl-2-(4-nitrophenoxy)acetamide (NPA). NPA has been shown to have antiangiogenic properties. NPA inhibits the proliferation of endothelial cells by interfering with the cell cycle and inducing apoptosis.</p>

<p>Versatile small molecule scaffold</p>

<p>The chemical is a palladium-based complex that inhibits the activity of α4β7 integrin. It has been shown to be effective in prophylaxis and treatment of inflammatory diseases, such as autoimmune diseases, and other conditions, such as congenital disorders. The compound has been shown to inhibit the growth of plants by causing phytotoxic effects.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 3-formyl-1H-pyrrole-2-carboxylate is a formyl compound with the molecular formula C8H8O3. It is a colorless liquid that has a strong odor. The compound can be obtained by the reaction of ethyl acetoacetate and pyrrole in the presence of aluminum chloride. The compound has been studied for its nuclear magnetic resonance (NMR) properties. It has two conformers, which are distinguished by their different chemical shifts, and this difference can be used to study coupling between the carbonyl group and other groups in the molecule.</p>

<p>1-chloro-4-fluoroisoquinoline is a chlorinating agent that has been used as a synthetic method for the synthesis of oxychloride. It is typically used in the presence of palladium catalyst, in the presence of phosphorus and under reductive conditions. The chlorination reaction is initiated by addition of hydrochloric acid or phosphorous oxychloride. The 1-hydroxyisoquinoline reacts with phosphorus to form a chloroformate, which reacts with fluorine gas to produce an intermediate chlorofluorinate. This intermediate then reacts with chlorine gas in the presence of palladium catalyst to generate the desired product, 1-chloro-4-fluoroisoquinoline.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Acetamidobenzenesulfonamide is a drug that inhibits the activity of several enzymes and is used in wastewater treatment. It has been shown to have a beneficial effect on metabolic disorders, such as insulin resistance, obesity, and type 2 diabetes. 4-Acetamidobenzenesulfonamide also regulates transcriptional activity by inhibiting the interaction between DNA and RNA polymerases. This drug has been shown to be active in treating autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis, lupus erythematosus and Crohn's disease. It also aids in HIV infection by acting as an inhibitor of toll-like receptor signalling pathways. The drug binds to hydrogen bonds and hydrophobic interactions with water molecules to form a hydrophobic layer on the surface of cells in order to reduce water permeability. The drug also reduces bowel diseases such as ulcerative colitis and liver lesions caused by alcohol consumption or congestive</p>

<p>3,3,5-Trimethylcyclohexanone is an intermediate in the synthesis of polymers and polyesters. This compound is a reactive hydrogenation product which can be used to produce polymers with desired properties. The unsaturated side chain of 3,3,5-trimethylcyclohexanone reacts with borohydride to form a ketal. After being converted to the corresponding acid chloride, the 3,3,5-trimethylcyclohexanone can be used for the synthesis of polyesters. This compound has also been shown to be an effective catalyst for producing β-unsaturated ketones from aldehydes and dienes.</p>

<p>Versatile small molecule scaffold</p>

<p>(2R,3S)-Benzyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate is a molecule with an enantioselective synthesis and a preparative method. It has been catalysed by chiral reagents such as chiral catalysts, chiral auxiliaries, and chiral ligands. This molecule can be synthesized in racemic form or in the form of its two enantiomers. The two enantiomers have different physical properties and biological activities. (2S,3S)-Benzyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate is known to be an inhibitor of protein kinase C (PKC) that causes the release of intracellular calcium ions from cytoplasmic stores. The other enantiomer (2R,3S)-benzyl 6-oxo-2,3-d</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Chromane-2-carboxylic acid is an amide with a hydroxy group that has inhibitory effects on alkoxyphenols. It has been shown to have the ability to inhibit the growth of cancer cells in mammalian tissue and has been used in synthesizing nitro compounds. Chromane-2-carboxylic acid also inhibits matrix metalloproteinases, which are enzymes that break down proteins in the extracellular matrix and are associated with tumor invasion and metastasis. This compound also has radical scavenging activities, which may be due to its ability to form hydrogen bonds or intramolecular hydrogen bonds with aromatic hydrocarbons or fatty acids.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Glycidyltrimethylammonium chloride is a quaternary ammonium compound that has been widely used as a disinfectant and in wastewater treatment. It is mainly used to kill bacteria and viruses, although it can also be used to remove hazardous material from water. Glycidyltrimethylammonium chloride has the ability to inhibit bacterial growth by causing cell membrane damage. This compound is also able to inhibit the synthesis of DNA, RNA, and protein in cells by binding to their respective building blocks. In addition, glycidyltrimethylammonium chloride has cytotoxic effects on human cells and significantly inhibits the replication of oral pathogens.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylbenzo[b]thiophene-2-carboxylic acid (MBTCA) is a heterocyclic compound that is an intermediate in the synthesis of 3-methylthiophene-2-carboxylic acid, a precursor to other drugs. MBTCA is an aerobic, nonpolar compound that has shown antimicrobial activity against some bacteria and fungi. It also has been shown to have practicality as a biomolecular probe for methyl groups in organic solvents. MBTCA can be synthesized by nitration of benzene in the presence of sulfur and sulfoxides. This reaction produces nitrobenzene, which can then be oxidized by potassium permanganate or hydrogen peroxide to produce MBTCA. The most common isomer of MBTCA is 2-(3,5-dimethoxybenzylidene)tetrahydrofuran, with three methyl groups on the</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Morpholin-4-yl)acetyl chloride hydrochloride is a fine chemical that is used as a building block for the synthesis of other compounds. It can be used in research and development, or as a reagent. 2-(Morpholin-4-yl)acetyl chloride hydrochloride has high purity and is easily soluble in water. This compound can be used as an intermediate to synthesize other compounds, or it can be used as a scaffold for the formation of complex structures.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Methoxyphenyl)ethyl bromide is an adenosine receptor antagonist that can be used in cancer treatment. It has been shown to inhibit the growth of cancer cells by blocking the binding of adenosine to its receptors and inhibiting phosphodiesterase, which is an enzyme that breaks down the key cellular messenger, cyclic AMP (cAMP). 2-(4-Methoxyphenyl)ethyl bromide also inhibits the production of aphanorphine, a morphine analogue that has been shown to stimulate endoplasmic reticulum stress and apoptosis in cancer cells. This compound has been synthesised and tested on animal models with promising results.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>p-Isobutylstyrene-d7 is a solid catalyst that can be used in the synthesis of organic compounds. It has been shown to have good activity for the transfer of acid chloride groups to aromatic ring systems and for the synthesis of thiadiazoles. p-Isobutylstyrene-d7 has been shown to be an excellent catalyst for the conversion of hydrochloric acid into hydrogen chloride, which can then be recycled. The toxicity studies on this compound have shown that it is not toxic to bacterial strains, which may make it a good candidate for use as a catalyst in bioremediation or a growth substrate. This catalyst has also been shown to have photocatalytic activity and may be used in the purification of water contaminated with heavy metals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Trans-3-(Benzyloxy)cyclobutanol is a radiolabeled compound that is used as a model system for understanding the metabolism of drugs in humans. It has been shown to be metabolized by the liver to produce metabolites that are excreted in urine. Trans-3-(Benzyloxy)cyclobutanol has also been shown to have tumor cell line stability, which may be due to its ability to inhibit DNA synthesis and protein synthesis in vitro and reduce tumor cells in vivo. Trans-3-(Benzyloxy)cyclobutanol has been shown to have no effect on normal rat plasma and lung carcinoma cells, but does affect prosthetic group activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>