Building Blocks

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Bromo-4-isobutylbenzene is a ketone that can be synthesized by the reaction of benzene with acetonitrile in the presence of a catalytic amount of oxone. The synthesis is an example of an arylation, which is the addition of an aromatic group to another molecule. It has been shown experimentally that 1-bromo-4-isobutylbenzene undergoes a transition from the x-ray structure analysis to the crystal x-ray structure when dissolved in acetonitrile and heated to 100°C. The final product is then purified by recrystallization with ethylene as a solvent.</p>

GSK'547 is a small molecule that can interact with the ferroptosis pathway, which is involved in both acute and chronic kidney injury. GSK'547 has been shown to inhibit ischemia reperfusion-induced renal dysfunction by suppressing inflammation and oxidative stress. GSK'547 also inhibits cancer cell proliferation and acts as an anti-inflammatory agent. In addition, GSK'547 has been shown to be beneficial for treating tuberculosis infections and cavity diseases. The mechanism of action of GSK'547 involves inhibiting bacterial cell wall synthesis by binding to the beta-subunit of DNA gyrase. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division.

<p>Bromo-PEG4-azide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromo-PEG4-azide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>4-Nitrophenylmethanethiol is a reactive molecule that reacts with dopamine D3, an important cytosolic protein, to form a stable covalent bond. This reaction was shown to be pH-dependent and the products were identified by x-ray diffraction data. The disulfide bond formed by this reaction is then reduced to the corresponding sulfhydryl group with sodium borohydride or hydroxide solution. 4-Nitrophenylmethanethiol also reacts with inorganic acid and sodium carbonate to form a molecule containing carbapenem, which is a model protein used in research on chemical reactions. 4-Nitrophenylmethanethiol reacts with chloride ions and phenyl groups to yield hydrochloric acid as the final product of the chemical reaction.</p>

<p>Dimethyl pyridine-3,4-dicarboxylate is an organic compound that is used as a precursor to make other chemicals. It is a pyridinedicarboxylic acid and it can be synthesized from the reduction of pyridine with sodium borohydride in ethanol. Dimethyl pyridine-3,4-dicarboxylate is also used in the production of acetaldehyde by way of hydrosilylation with chloride and chloroform. This chemical has been found to be useful for the synthesis of various drugs such as antiepileptics, antihistamines, antipsychotics, and antidepressants.</p>

<p>Nerol oxide is a natural compound and fragrance ingredient that has been shown to have anti-aging effects. Nerol oxide is an ester of citronellal, nerolic acid and ethyl decanoate. It is found naturally in orange blossoms and other citrus plants, as well as in lavender oil. Nerol oxide can be extracted from the plant material using solid phase microextraction. The chemical analyses of this extract reveal the presence of various fatty acids, including ethyl esters, fatty acids and their corresponding alcohols. These compounds are used to produce nerol oxide by polymerization with an initiator such as potassium hydroxide or sodium hydroxide at a neutral pH.</p>

<p>3,6-Dichloropicolinonitrile is a peroxide that is used in the synthesis of organic compounds. It is produced by the reaction of sodium carbonate and hydrochloric acid with nitric acid as a catalyst. 3,6-Dichloropicolinonitrile has been shown to be more selective than other oxidizing agents such as hydrogen peroxide and potassium permanganate. The product can then be purified by adding diacetate, which selectively reacts with the chlorine to form acetyl chloride and glycolic acid. The resulting mixture can then be distilled to produce 3,6-dichloropicolinonitrile in high purity. 3,6-Dichloropicolinonitrile can also be used in electrochemical methods for the synthesis of cyanides or biochemically for virulent products such as pesticides and organic solvents.</p>

Versatile small molecule scaffold

<p>1-Phenyl-1H-pyrazol-4-amine is a white crystalline solid that can be used in organic synthesis. It is soluble in water and acetone, but insoluble in ether and chloroform. The chemical formula for 1-phenyl-1H-pyrazol-4-amine is C6H5N3O. It has a molecular weight of 147.17, an empirical formula of C6H5N3O and a density of 1.47g/mL at 20°C. 1-Phenyl-1H-pyrazol-4-amine reacts with the hydroxyl group on l -glutamic acid to form the corresponding ester, which can be hydrolyzed under alkaline conditions to produce ammonia and benzoic acid. This molecule also contains an anion that can be deprotonated by an alkali metal such as sodium or potassium to form the corresponding salt, which</p>

<p>2-Mercaptopyridine is a quinone that has been used as an inhibitor of the HIV reverse transcriptase enzyme. It binds to the active site of the enzyme and inhibits its activity by forming a stable covalent bond with two cysteine residues in the enzyme. The molecule is stabilized by two adjacent sulfide bonds, which form a six-membered ring with three nitrogen atoms and one oxygen atom. This ring coordinates to the zinc ion in the active site of the enzyme. 2-Mercaptopyridine has also been found to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. 2-Mercaptopyridine binds to DNA at positions where it is complementary to guanine or adenine nucleotides, thus preventing RNA synthesis and replication.</p>

<p>N-alpha-Z-L-lysine methyl ester hydrochloride is a preparation that is used as a methyl ester. It is an ester of lysine and methyl chloride. This product has a molecular weight of 170.16 g/mol and the chemical formula CH3CONHCH2CH(NH)CO2CH3. The structural data has not been confirmed by X-ray crystallography, but it can be assumed to be in the form of a zwitterion. N-alpha-Z-L-lysine methyl ester hydrochloride can be used for the synthesis of peptides, which are building blocks for proteins and enzymes. N-alpha-Z-L-lysine methyl ester hydrochloride is also used in the production of certain kinds of drugs and organic acids such as acetylsalicylic acid (aspirin).</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-bromo-6-methoxy-1H-indole is a synthetic, nonsteroidal compound that is structurally related to prednisolone. It has been shown to induce the synthesis of collagen by stimulating fibroblasts in culture. This drug also has anti-inflammatory and modulating effects on s1p receptors, which may be due to its ability to inhibit the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). 5-bromo-6-methoxy-1H-indole is a potent inhibitor of acid methyl esters, which are involved in inflammation and tissue destruction. 5-bromo-6-methoxy-1H--indole also has an effect on dermal cells, which may be due to its ability to inhibit the production of matrix metalloproteinase enzymes. This drug can also cause atrophy in granuloma cells and prevent the development of inflammatory</p>

<p>Methyl 2-(chloromethyl)nicotinate is an organic compound that belongs to the class of esters. It is a reaction product of methyl 3-hydroxybenzoate and nitrous acid. This compound has antimicrobial activity and can be used to treat bacterial infections. Methyl 2-(chloromethyl)nicotinate has been shown to inhibit the growth of various bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, and Salmonella typhimurium. The cyano group in this molecule may be responsible for its antibacterial activity. <br>The efficiency of methyl 2-(chloromethyl)nicotinate varies with different types of bacteria. For example, it was more effective against MRSA than against Escherichia coli or Klebsiella pneumoniae</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Glycidyltrimethylammonium chloride is a quaternary ammonium compound that has been widely used as a disinfectant and in wastewater treatment. It is mainly used to kill bacteria and viruses, although it can also be used to remove hazardous material from water. Glycidyltrimethylammonium chloride has the ability to inhibit bacterial growth by causing cell membrane damage. This compound is also able to inhibit the synthesis of DNA, RNA, and protein in cells by binding to their respective building blocks. In addition, glycidyltrimethylammonium chloride has cytotoxic effects on human cells and significantly inhibits the replication of oral pathogens.</p>

Versatile small molecule scaffold

<p>3-Methylbenzo[b]thiophene-2-carboxylic acid (MBTCA) is a heterocyclic compound that is an intermediate in the synthesis of 3-methylthiophene-2-carboxylic acid, a precursor to other drugs. MBTCA is an aerobic, nonpolar compound that has shown antimicrobial activity against some bacteria and fungi. It also has been shown to have practicality as a biomolecular probe for methyl groups in organic solvents. MBTCA can be synthesized by nitration of benzene in the presence of sulfur and sulfoxides. This reaction produces nitrobenzene, which can then be oxidized by potassium permanganate or hydrogen peroxide to produce MBTCA. The most common isomer of MBTCA is 2-(3,5-dimethoxybenzylidene)tetrahydrofuran, with three methyl groups on the</p>

<p>3,4,5-Trimethoxybenzoyl Chloride is a reactive, active chemical that is used in the synthesis of cytotoxic amides. It is prepared by reacting 3,4,5-trimethoxybenzoic acid with an amine or ammonia in the presence of a base. The reaction yields an amide substituted at the 3- and 4-positions with trimethoxyphenyl groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Azidoethoxy)acetic Acid is a hydrophobic antibacterial agent that can be used to inhibit bacterial growth by disrupting the cell membrane. It has been shown to inhibit the growth of Staphylococcus aureus and Escherichia coli, which may be due to its ability to bind to the glutathione moiety in the bacterial cell membrane. 2-(2-Azidoethoxy)acetic Acid has been shown to have antimicrobial activity against both Gram-positive and Gram-negative bacteria in vitro. This compound is also able to cross the cell membrane, inhibiting bacterial replication in vivo.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[[(3aS,4R,6S,6aa)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]- 2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol-d7 is a compound with brominated sparfloxacin. It has various applications in the field of biochemistry and research chemicals. This compound has been found to have interactions with adipocytes and adipose tissues. Additionally, it has shown potential effects on glycan metabolism and potassium ion channels. Furthermore, this compound has been studied for its potential as an herbicide and its interaction with other substances such as</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Iodo-1-methyl-1H-pyrazole-5-carbonitrile is a tetrazole molecule that has been shown to have potent and selective inhibitory activity against human PCSK9. This compound binds to the catalytic site of PCSK9 and prevents the formation of an active enzyme, therefore inhibiting the production of LDL cholesterol. 4-Iodo-1-methyl-1H-pyrazole-5-carbonitrile is a prodrug that is metabolized by acetaldehyde dehydrogenase to form an active inhibitor. The reaction proceeds in a chiral and enantioselective manner, which allows for the synthesis of racemic mixtures of this drug.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Acetylbenzoic acid is a functional molecule that contains an acetyl group. It can form hydrogen bonds with other molecules and has been shown to induce apoptosis in cells. The reaction products of 2-acetylbenzoic acid are malonic acid, acetylsalicylic acid, and 2-benzoylbenzoic acid. These three compounds are made by the addition of hydrogen or hydroxide to the molecule 2-acetylbenzoic acid. The molecule has two functional groups: a carbonyl group and an acetyl group. The chemical structure of this molecule can be seen in the figure below.<br>2-Acetylbenzoic Acid</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

1-Adamantane carboxylic acid is a hydrophobic molecule that can form a complex with metal hydroxides. It is used in the process optimization of the synthesis of sodium salts. 1-Adamantane carboxylic acid binds to metals, such as magnesium and calcium, in a coordination geometry that is similar to that observed for water molecules. The complexation of 1-Adamantane carboxylic acid with metal ions results in an acidic environment, which is important for bowel disease. This acid complex also has anti-inflammatory properties. The hydroxyl group on the 1-adamantane carboxylic acid reacts with oxygen to form an alcohol group and this reaction mechanism may be involved in physiological functions.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-4-bromopyridine is a potent, selective antagonist of the nicotinic acetylcholine receptor (nAChR) that has been shown to inhibit the proliferation of cancer cells in vitro. 2-Amino-4-bromopyridine binds to the nAChR and stabilizes it by binding to an allosteric site on the receptor. 2-Amino-4-bromopyridine is synthesized from 4,5-dibromobenzene and 2,6-diaminopyridine in two steps with a yield of 47%. The synthesis of 2-amino-4-bromopyridine proceeds via reaction mechanism involving electrophilic substitution at the bromine atom followed by nucleophilic addition at the nitrogen atom.</p>

2-Imidazolidone-4-carboxylic acid is a potent inhibitor of matrix metalloproteinases, which are enzymes that break down proteins in the extracellular matrix. 2-Imidazolidone-4-carboxylic acid inhibits the activity of both serine protease and matrix metalloproteinase, two enzymes involved in the inflammation process. 2-Imidazolidone-4-carboxylic acid has been shown to inhibit the transport of amino acids, leading to decreased protein synthesis and cell growth. It also inhibits cancer cells by disrupting their ability to grow new blood vessels and invade other tissues.

<p>Fmoc-a-Me-Lys(Boc)-OH is a versatile building block that can be used in the synthesis of complex compounds. It is a reagent and speciality chemical, which are substances used in research laboratories. Fmoc-a-Me-Lys(Boc)-OH has been used as an intermediate in the synthesis of drugs such as antihypertensive agents, anticonvulsants, and antibiotics. It has also been used as a reaction component in organic syntheses to produce peptides, polymers, and other compounds with biologically active properties.</p>

<p>Fmoc-Lys-OH·HCl is an acidic pyrylium that has been shown to be a potent inhibitor of tumor vasculature. It binds to the human serum albumin and inhibits the binding of ligands to the receptor tyrosine kinases, which are involved in brain tumor proliferation. Fmoc-Lys-OH·HCl has also been shown to inhibit the growth of cancer cells by binding to cell membrane receptors and inhibiting protein synthesis. This compound is also isomeric, meaning it can exist in different forms with different properties.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Piperazin-1-yl)butan-1-one is a neoplastic cell growth inhibitor that inhibits the proliferation of myeloid, k562 and HL60 cells. It has been shown to inhibit the growth of tumor cells in vitro. 1-(Piperazin-1-yl)butan-1-one is an analog of piperazine, which is known to be a cytotoxic agent with anticancer activity. The mechanism of action is not known, but it may be due to its ability to inhibit DNA synthesis or its inhibition of protein synthesis.</p>

<p>L-Glutamic acid 5-benzyl ester is an amino acid that has been synthesized to have a lysine residue. It is an ester hydrochloride and has been shown to have broad-spectrum antimicrobial properties. L-glutamic acid 5-benzyl ester's antimicrobial activity is thought to be due to its chemical structure which allows it to act as an antimicrobial peptide, binding to receptors on the surface of bacterial cells and inhibiting their growth. L-glutamic acid 5-benzyl ester also inhibits osteogenic genes in cervical cancer cells, but not in normal cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Morpholin-4-yl)acetyl chloride hydrochloride is a fine chemical that is used as a building block for the synthesis of other compounds. It can be used in research and development, or as a reagent. 2-(Morpholin-4-yl)acetyl chloride hydrochloride has high purity and is easily soluble in water. This compound can be used as an intermediate to synthesize other compounds, or it can be used as a scaffold for the formation of complex structures.</p>

<p>4-Hydroxybenzenesulfonic acid is a chemical compound that is used as an antimicrobial agent in industrial applications. It is commonly used as a corrosion inhibitor, a chelating agent, and an additive for detergents and other cleaning products. 4-Hydroxybenzenesulfonic acid has been shown to inhibit the growth of bacteria by binding to fatty acids in the cell membrane and preventing them from being incorporated into the cell wall. This process causes the cell wall to weaken and eventually rupture. The reaction mechanism of 4-hydroxybenzenesulfonic acid is similar to that of p-hydroxybenzoic acid, which also inhibits bacterial growth by attacking fatty acids in the cell membrane. 4-Hydroxybenzenesulfonic acid may be preferable because it can be produced from renewable sources rather than from petroleum or natural gas.</p>

<p>3,3²-Dithiobis(propionitrile) is a molecule that includes sodium hydroxide solution and acrylonitrile. It reacts with 3-mercaptopropionic acid to form sodium hydrogen ester compounds. This reaction takes place in a sealed container and is catalyzed by carbonic and hydrochloric acids. The product of this reaction is 3-thiocyanatoacrylic acid.</p>

<p>4-(2-Bromoethyl)morpholine hydrobromide is a solvent that is used as an agent in the production of other chemicals. It is a colorless, crystalline solid with a constant melting point of 130 to 131 degrees Celsius. 4-(2-Bromoethyl)morpholine hydrobromide is soluble in acetone, ethanol, ether, and water. This chemical has been shown to be toxic and should be handled with care.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile is a redox molecule that emits light when excited by an electron or photon. It is used in organic light emitting devices (OLEDs) as the emissive material. This compound has been shown to have low chemical stability and limited transport properties. Its efficiency can be improved by increasing the concentration of the molecule. Activated 2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile emits a bright red orange emission with a maximum at 569 nm and it is activated by electron transfer from an electrode. 2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile has been shown to emit blue light when excited by UV light in the presence of oxygen as an oxidant.</p>

<p>Versatile small molecule scaffold</p>

<p>(S)-1-N-Boc-2-methylpiperazine is a quinolone synthon that has been shown to have antibacterial activity against bacteria. The synthesis of this compound is done through the condensation of piperazine with an N-Boc protected 2,6-dichloroquinoline. This reaction proceeds in good yield and enantioselectivity. The antibacterial properties of (S)-1-N-Boc-2-methylpiperazine are not yet known.</p>

<p>Please enquire for more information about N-Me-D-Ala-OMe·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methylenepiperidine hydrochloride is a synthetic, ethylene oxide derivative that is used as an antifungal drug. It is also used in the synthesis of other compounds and as a reagent in organic chemistry. 4-Methylenepiperidine hydrochloride can be synthesized by reacting ethylene with an alkoxide, followed by adding a metal halide such as organolithium reagents to form the desired product. The yield rate of this reaction is high and it is easy to perform on a large scale.</p>

<p>Please enquire for more information about 2-Methyl-2H-indazol-5-ylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Leu-Leu-Leu-OH is a pentapeptide that is used in cancer treatment to inhibit the growth of cancer cells. It prevents the production of proteins and, as a result, cell division. Leu-Leu-Leu-OH has been shown to be effective against tumor cells with an antibody that binds to the surface of cells. The monoclonal antibody is taken up by the cancer cells through receptor mediated endocytosis, which leads to inhibition of protein synthesis and cell death.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Iodobenzoic acid methyl ester is a palladium complex that can be used as a catalyst for the hydrolysis of ketoesters, imines, and halides. The reaction mechanism involves the coordination of the metal center to the carboxylate or amine group on the substrate, followed by a nucleophilic attack at the benzoate or chloride group. The resulting product is an alkyl halide. 2-Iodobenzoic acid methyl ester has been shown to catalyze the cross-coupling of diphenyl ethers with various amines in water and in organic solvents.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(p-tolyl)propiolic acid is a functional group that is used in organic chemistry. It is an alkynoic acid with a terminal triple bond. The compound can be synthesized by the reaction of propiolic acid with an alkyne, followed by oxidation. The 3-(p-tolyl)propiolic acid can be used as a surrogate for other functional groups in organic synthesis, and it has been shown to react as an oxidant in biomolecular systems.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Iodobenzoic acid is a synthetic compound that is used in the treatment of wastewater. It is produced by the reaction of benzoate and nitrite in the presence of sodium hydroxide. The intramolecular hydrogen atom transfer from the 2-iodobenzoic acid to benzoate is a reversible reaction. This process can be catalyzed by palladium, which has been shown to be effective in coupling 2-iodobenzoic acid with other compounds to produce cyclic peptides. The use of 2-iodobenzoic acid as a contraceptive has been investigated for its ability to inhibit acetylcholinesterase activity, which may lead to increased levels of acetylcholine and inhibition of muscle contractions.</p>

<p>p-Isobutylstyrene-d7 is a solid catalyst that can be used in the synthesis of organic compounds. It has been shown to have good activity for the transfer of acid chloride groups to aromatic ring systems and for the synthesis of thiadiazoles. p-Isobutylstyrene-d7 has been shown to be an excellent catalyst for the conversion of hydrochloric acid into hydrogen chloride, which can then be recycled. The toxicity studies on this compound have shown that it is not toxic to bacterial strains, which may make it a good candidate for use as a catalyst in bioremediation or a growth substrate. This catalyst has also been shown to have photocatalytic activity and may be used in the purification of water contaminated with heavy metals.</p>

<p>Isocytosine is a prodrug that has been synthesized with the intramolecular hydrogen on the nitrogen atoms, which makes it more chemically stable. Isocytosine is a reactive molecule, and can react with tautomers to form isocytosine derivatives. Isocytosine contains three hydrogen atoms that are transferable through reactions to other molecules. The chemical stability of isocytosine allows for its use in wastewater treatment. It also has metabolic effects, such as the inhibition of colorectal adenocarcinoma and metabolic disorders. Isocytosine can be used as a model system for studying transfer reactions and reaction mechanisms.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Ethynylbenzenesulfonamide is a synthetic, hydrophobic, antimicrobial compound that disrupts the cell membrane. It has been shown to be effective against both mammalian and microbial cells. The antimicrobial use of this compound is still under study, but it may provide an alternative to the current antibiotics. 3-Ethynylbenzenesulfonamide is amphipathic in nature and has an extremely large expansion ratio. This molecule is also hydrophobic, which may help with its ability to penetrate the cell membrane. Antimicrobial compounds are designed to inhibit or kill microorganisms such as bacteria or fungi by disrupting their cellular membranes. They work by interacting with specific targets on the surface of the target organism and producing a lethal effect on its function. 3-Ethynylbenzenesulfonamide interacts with proteins found on bacterial membranes called porins, resulting in a loss of osmotic stability and then permeability through the bilayer. This leads</p>

<p>1H-[1,2,3]Triazolo[4,5-d]pyrimidin-5-amine is a nitro compound that binds to the receptor binding sites of certain inflammatory bowel disease and cancer cells. It also inhibits the production of adenosine in these cells. 1H-[1,2,3]Triazolo[4,5-d]pyrimidin-5-amine has been shown to be effective against bowel disease and cancer by inhibiting cyclic AMP (cAMP) degradation. This drug has also been shown to be an irreversible inhibitor of ischemia reperfusion injury in animal models. 1H-[1,2,3]Triazolo[4,5-d]pyrimidin-5-amine is a nitro compound that binds to the receptor binding sites of certain inflammatory bowel disease and cancer cells. It also inhibits the production of adenosine in these cells. 1H</p>

<p>Versatile small molecule scaffold</p>

<p>Di(1-adamantyl)chlorophosphine is a bifunctional ligand that can be used for the palladium-catalyzed coupling of aryl chlorides and amines. Di(1-adamantyl)chlorophosphine is synthesized from adamantane, phosphorous pentachloride, and anhydrous ammonia in the presence of catalytic amounts of palladium. Di(1-adamantyl)chlorophosphine is immobilized on silica gel to prevent hydrolysis. This ligand reacts with primary amines to form iminophosphoranes, which can then be reacted with aryl chlorides to form aryl chloroamines.</p>

<p>Versatile small molecule scaffold</p>