Amines

<p>Applications 2-[(Dipropylamino)sulfonyl]benzoic Acid, is a building block used in various chemical synthesis.<br></p>

<p>Applications N-[[4-(Phenylmethoxy)phenyl]methyl]-2-[(3-thienylcarbonyl)amino]-4-thiazoleacetamide is derived from ethyl 2-amino-4-thiaxolacetate (E899330) which is used in the synthesis of various pharmaceutical and biologically active compounds including inhibitors and antibiotics.<br>References Inamoto, Y., et al.: J. Antibiot., 41, 828 (1988)<br></p>

<p>Applications Cyclopentylamine is a useful synthetic intermediate. It was used to prepare chiral N-aminoacyl pyrrolidines and (adamantylamino)acetamides as selective and orally bioavailable dipeptidyl peptidase IV inhibitors with antihyperglycemic properties. It is also a reagent used to prepare dipeptidyl peptidase IV inhibitors as potent anti-diabetic agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Villhauer, E., et al.: J. Med. Chem., 46, 2774 (2003); Ahn, J., et al.: Bioorg. Med. Chem. Lett., 14, 4461 (2004)<br></p>

<p>Applications 5-Aminoboronphthalide is used as a reactant in the preparation of 2,1-benzoxaborole peptide isoquinoline derivatives as HCV NS3 protease inhibitors. It is also used as reactant in the synthesis of nanocarrier for chemomechanically driven guest delivery fueled by intracellular ATP.<br>References Li, X., et al.: Bioorg. Med. Chem. Lett., 21, 2048 (2011); Biswas, S., et al.: Nat. Chem., 5, 613 (2013);<br></p>

<p>Applications Dimethylamine (40% aq.) is a compound often used in industry as a precursor to Nitrosodimethylamine (N525625), a potent carcinogen that is produced during disinfection of wastewater effluent, and is also present in trace amounts in food and polluted air. Dimethylamine is also present in human urine and can be indicative of certain disorders.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gereke, A. &amp; Sedlak, D.: Env. Sci. Tech., 37, 1331 (2003); Mitch, W., et al.: Env. Eng. Sci., 20, 389 (2003); Tsikas, D., et al.: J. Chromatogr. B, 851, 229 (2007)<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester<br></p>

<p>Applications 4,4'-Dimethyldiphenylamine is a reagent used in the comparative studies of the analgesic and anti-inflammatory properties of N-phenylanthranilic acids and mefenamic acid, and the anti parasitic activities of some substituted diphenylamines.<br>References Izard-Verchere, C., et al.: Chimica Therapeutica, 6, 346 (1971)<br></p>

<p>Applications 2-Amino-5-formylthiazole is a useful reagent for the preparation of cationic azo dyes.<br>References Salvador, M. A., et al.: Dyes and Pigments, 82, 118 (2009); Salvador, M. A., et al.: Tetrahedron, 64, 299 (2008)<br></p>

<p>Applications 2-(6-Aminopurin-9-yl)ethanol is a useful intermediate in the preparation of aryloxyalkyl derivatives of adenine with antiviral activity.<br>References Petrov, V. I., et al.: Chemistry of Heterocyclic Compounds, 39, 1218 (2003)<br></p>

<p>Applications 2-amino-2-cyclopropylpropan-1-ol (cas# 1184403-67-5) is a useful research chemical.<br></p>

<p>Applications N,N-Dimethyl-p-phenylenediamine (DMPD) has been used to n-dope bilayer graphene (BG) along with p-dope of tetracyanoethylene bilayer graphene to increase the band gap of DMPD/BG. N,N-Dimethyl-p-phenylenediamine (DMPD) has been shown to inhibit corrosion of mild steel in a sulphuric acid medium.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, T.H., et. al.: J. Phys. Chem. C., 117, 12873 (2013); Singh, K.U., Dubey, R.S.: Int. J. Chem., 1, 366 (2012)<br></p>

<p>Applications Ammonium 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonate (CAS# 29081-56-9) is a fluorosurfactant used as an additive to increase heat stability and resistance of materials.<br>References Gloeckner, V.; et al.: Tenside, Surfactants, Detergents, 26, 376 (1989).<br></p>

<p>Applications N-Acetylethanolamine can be used as an antistatic agent, foam boosting agent, hair conditioning humectant, skin conditioning surfactant and viscosity controlling agent in cosmetics industry. It is a non-tacky glycerine alternative for use in skin and hair care.<br>References Hough, L., et al.: J. Chem. Soc., 7923994-3997 (1957); Auzanneau, F-I, et al.: J. Chem. Soc., 10, 2831-2834 (1990);<br></p>

<p>Applications 5-Aminopentanenitrile Hydrochloride is a useful research chemical.<br></p>

<p>Applications N-(2-aminoethyl)benzamide (cas# 1009-17-2) is a useful research chemical.<br></p>

<p>Applications ethyl 4-aminopentanoate hydrochloride (cas# 119396-97-3) is a useful research chemical.<br></p>

<p>Applications 3-Amino-2-hydroxybenzonitrile<br></p>

<p>Stability Hygroscopic<br>Applications 5-(4-aminophenyl)-1,3,4-oxadiazol-2-ol (cas# 113118-47-1) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications A multifunctional compound which shows antioxidant activity in a skin cell model of UVA-induced stress.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sies, H., et al.: Eur. J. Biochem., 215, 213 (1993), Meotti, F., et al.: Environ. Res., 94, 276 (2004),<br></p>

<p>Applications 3-[(2-Hydroxyethyl)Amino]Propanoic Acid (cas# 5458-99-1) is a useful research chemical.<br></p>

<p>Applications N-Phenyl-4-biphenylamine (cas# 32228-99-2) is a useful reagent for the preparation of heterocyclic compounds for organic electrical devices.<br>References Oh, H. J., et al.: Repub. Korean Kongkae Taeho Kongbo (2020), KR 2020095104 A<br></p>

<p>Applications 2-(methylamino)octanoic acid (cas# 101080-67-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications A useful synthetic intermediate.<br></p>

<p>Applications 3-Aminocyclohexanol_x000D_(cis/trans mixture) (cas# 6850-39-1) is a compound useful in organic synthesis.<br></p>

<p>Applications Tetrahydro-3-furanmethanamine is an intermediate in the synthesis of Dinoteturan (D482100), a neonicotinoid insecticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1,3-Diamino-2-propanol is a reagent used in the quantitative fluorescent detection of pyrophosphate with quinolin-ligated dinuclear zinc complexes.<br>References Mikata, Y., et al.: Inorg. Chem., 52, 10223 (2013)<br></p>

<p>Impurity Vildagliptin Impurity<br>Applications 1-Amino-3-nitroadamantane has potential application in co-catalyst for transition metal reactions and maybe a useful intermediate for the synthesis of Vildagliptin (V305000), an antidiabetic drug that inhibits dipeptidyl peptidase 4 (DPP-4). Vildagliptin exhibits antioxidant properties and may be an apoptotic compound against pancreatic cancer cells.<br>References Amritha, C., et al.: JCDR 9, FC14 (2015); Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004)<br></p>

<p>Applications 4-(Methylsulfinyl)-1-butylamine (cas# 187587-70-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Z-3-(Tributylstannyl)-2-propen-1-amine (cas# 146829-37-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Ammonium Hydroxide is in numerous household cleaning agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lokshin, E.P., et al.: Russ. J. App. Chem., 86, 450 (2013); Alghamdi, A.A., et al.: J. Material. Chem. A. Mater. Energy. Sustain., 1, 5165 (2013);<br></p>

<p>Applications 2-Amino-2-butenediamide (cas# 18486-76-5) is a compound useful in organic synthesis.<br></p>

<p>Stability Light Sensitive<br>Applications (E,E)-5-[4-(Diethylamino)phenyl]penta-2,4-dienal is used in polymerization process.<br>References Innocenzi, P., et al.: J. Mater Chem., 15, 3821 (2005), Cai, Y., et al.: Polymer, 2006, 47, 6560 (2006),<br></p>

<p>Applications 3-(N,N-Dimethylamino)phenylboronic Acid (cas# 178752-79-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Used in the preparation of homobifunctional rhodamine for labeling proteins.<br>References Corrie, J. et al.; Bioconjugate Chem. 9, 160 (1998)<br></p>

<p>Applications 9,9-Dimethyl-N-phenyl-9H-fluoren-2-amine is useful for the synthetic preparation of secondary amines.<br>References Yao, W., et al.: Catal. Sci., 9, 3874 (2019)<br></p>

<p>Applications A potent γ-ketoaldehyde scavenger that has been shown to protects cardiac sodium channel (NaV1.5) from oxidant-induced inactivation<br>References Zagol-Ikapitte, I. et al.: Pharmaceutics, 2, 18 (2010); Nakajima, T. et al.: J. Mol. Cell. Cardiol., 48, 352 (2010); Davies, S.S. et al.: Biochem., 45, 15756 (2006);<br></p>

<p>Applications Methyl 4-amino-2,3,5,6-tetrafluorobenzoate (cas# 715-37-7) is a useful research chemical.<br></p>

<p>Applications 4-(Ethylmethylamino)butanal Diethyl Acetal is a useful research chemical.<br></p>

<p>Applications 4-Dimethylamino-4'-nitrostilbene (cas# 4584-57-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-(Ethylamino)ethanol is used in the preparation of novel indole-2-carboxamide and 3-acetamide derivatives as antioxidant protective agents. Also used in the synthesis of novel amino acid based arginase inhibitors used towards the treatments of myocardial ischemia reperfusion injury.<br>References Oelgen, S. et al.: J. Enz. Inhib. Med. Chem., 28, 58 (2013); Van Zandt, M. et al.: J. Med. Chem., 56, 2568 (2013);<br></p>

<p>Applications 4-(dimethylamino)-3-nitrobenzoic Acid (cas# 28096-56-2) is a useful research chemical.<br></p>

<p>Applications Benzyl (2S)-2-carbobenzyloxyamino-6-hydroxyhexanoate (cas# 84246-49-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(2-AMINO-5-HYDROXYPHENYL)ETHANONE (cas# 30954-71-3) is a useful research chemical.<br></p>

<p>Applications Methyl 5-Chloro-2-[(4-ethoxy-4-oxobutyl)amino]benzoate is a reactant in the synthesis of 7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzoazepin, an intermediate in synthesis of Tolvaptan (T536650).<br>References Liu, Dengke, et al.: Tianjin Institute of Pharmaceutical Research, CN 103012265 A 20130403(2013);<br></p>

<p>Applications Extremely hindered tertiary amine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Burdick, J., et al.: Biomaterials, 22, 1779 (2001), Liu, V., et al.: Biomed. Microdev., 4, 257 (2002),<br></p>

<p>Applications N-[3-(4-Aminophenyl)propyl]-N,N-dimethylamine<br></p>

<p>Applications Ethylammonium Thiocyanate is used in the study of protic ionic liquid nanostructure.<br>References Hayes, R., et al.: Angewandte Chemie, International Edition, 52, 4623 (2013); Murphy, T., et al.: J. Phys. Chem., 118, 12017 (2014)<br></p>

<p>Applications (Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetic Acid can be used to synthesize cephalosporin derivatives and β-lactam antibiotics.<br>References Lee, H., et al.: Synth. Comm. 28, 1339 (1998); Bucourt, R., et al.: Tetrahedron 34, 2233 (1978); Borowwicz, P., et al.: PL 154681 B1 19910930 (1992); Hecker, S., et al.: US 5756493 A 19980526 (1998)<br></p>

<p>Stability Volatile<br>Applications N-Ethylbutylamine is used as a reagent in the synthesis of substituted pyrimidines as corticotropin releasing factor (CRF) receptor ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kuppast, B., et al.: Eur. J. Med. Chem., 78, 1 (2014)<br></p>

<p>Applications 2-(Methylamino)benzamide (cas# 7505-81-9) is a useful research chemical.<br></p>

<p>Applications A compound used in anti-corrosive coating material for the prevention of corrosion in metals.<br>References Weng, C. et al.: Chem. Mat., 22, 2075 (2011);<br></p>

<p>Applications 3-Amino-1,2-propandiol is used in the synthesis of Decarbazolyl Carvedilol (D212720), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schaefer, W.H. et al.: Drug. Metab. Dispos., 26, 958 (1998); Neugebauer, G. &amp; Neubert, P.: Eur. J. Drug. Metabol. Ph., 16, 257 (1991); Neugebauer, G. et al.: J. Cardiovasc. Pharm., 10, S85 (1987)<br></p>

<p>Applications 3-[(Dimethylamino)carbonyl]phenol can be used in the synthesis of novel purine and bicyclic pyrimidine, which are factor Xa inhibitors, and also have high selectivity over thrombin and trypsin.<br>References Buckman B. O., et al.: Bio. Med. Chem. Let., 8, 2235 (1998)<br></p>

<p>Stability Air Sensitive, Light Sensitive<br>Applications 2-Amino-4-cyano-phenol<br></p>

<p>Applications [4-[3-[[(Methylamino)methylene]amino]phenyl]-2-thiazolyl] Guanidine is a guanidino heterocyclic phenylamidines with pharmaceutical properties.<br>References Bietti, G., et al.: Eur. Pat. Appl. (1983), EP 89730 A2 19830928<br></p>

<p>Applications Tetrabutylammonium Azide (cas# 993-22-6) is a useful research chemical.<br></p>

<p>Applications 5-Bromopentyltrimethylammonium Bromide (cas# 15008-33-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,6-Diaminoquinazoline is used in the preparation of potential nociceptin receptor (NOP) antagonists. 4,6-Diaminoquinazoline is a predicted metabolite of 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline (A621350).<br>References Sestili, I. et al.: Eur. J. Med. Chem., 39, 1047 (2004);<br></p>