Carboxylic Acids

<p>Applications (±)-2-Acetoxybutyric Acid is an intermediate in synthesizing 2-Hydroxy-N-(pyridin-4-yl)butanamide (H953495). It is a is a useful synthetic intermediate.<br></p>

<p>Applications Racecadotril intermediate. A β-thiopropionyl-amino acid derivative used as β-lactamase inhibitor.<br>References Sanger, F., et al.: Biochem. J., 39, 507 (1945), Dawson, P., et al.: Science, 266, 776 (1994),<br></p>

<p>Applications 2-Ethylheptanoic Acid is used in the preparation of prostaglandin which is for for promoting bone growth<br>References Barrett, S., et al.: PCT Int. Appl., 331 (2015)<br></p>

<p>Applications 5-Pyrimidylboronic Acid, is one of the new heteroarylpyrimidine derivatives via Suzuki cross-coupling reactions.<br>References Saygili N, et al.: Org Biomol Chem. 2004 Mar 21;2(6):852-7. Epub 2004 Feb 23.<br></p>

<p>Applications 3-((E)-(2,4-Dimethylphenyl)diazenyl)-2,4-dihydroxy-5-((4-sulfophenyl)diazenyl)benzoic Acid is an intermediate in the synthesis of Acid Orange 24 (A189835), which is used in trickling biofilters for wastewater treatment. Acid Orange 24 is used in suncare compositions. It also serves as a raw material for cosmetics. Mutagenicity test for dye compositions in cosmetics.<br>References Garzon-Zuniga, M. A., et al.: Water Environ. Res., 83, 107 (2011); Anon.: IP.com Journal, 11, 5 (2011); Muzzall, J. M., et al.: Mutat. Res., Genet. Toxicol. Testing, 67, 1 (1979)<br></p>

<p>Applications 3-​Hydroxypivalic Acid is a general reagent used in the synthesis of AZD8835, a potent and selective inhibitor of PI3K and PI3Kδ in the treatment of cancers.<br>References Barlaam, B. et al.: Bioorg. Med. Chem. Lett., 25, 5155 (2015);<br></p>

<p>Applications 2-benzylcyclopropane-1-carboxylic acid (cas# 103986-55-6) is a useful research chemical.<br></p>

<p>Applications 2-Butyl-4,6-dihydroxybenzoic Acid is an intermediate in preparation of compounds for study in primin and miconidin biosynthesis routes in Primula obconica.<br>References Horper, W., et al.: Phytochem., 41, 451 (1996);<br></p>

<p>Applications Methyl 2-Bromo-1-cyclopentenecarboxylate is a versatile reactant that can be derived from Cyclopentanone (C988395), which is a compound used in the synthesis of various simple and complex organic compounds. Cyclopentanone is also used in the synthesis of peptidase IV inhibitors for the treatment of type 2 diabetes.<br>References Imamoto, T. et al.: J. Am. Chem. Soc., 112, 5244 (1990); Augeri, D. et al.: J. Med. Chem., 48, 5025 (2005);<br></p>

<p>Applications Trimethyl Bromoorthoacetate is an intermediate in the synthesis of 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid (B444100), an impurity of Clavulanic Acid (C563750).<br>References Zupke, C., et al.: Biotechnol. Prog., 10, 489 (1994), Finlay, J., et al.: J .Antimicrob. Chemother., 52, 18 (2003),<br></p>

<p>Applications Ethyl 2-Ethylacetoacetate was a useful reagent in systematic investigation of saccharomyces cerevisiae enzymes catalyzing carbonyl reductions.<br>References Kaluzna, I., et al.: J. Am. Chem. Soc., 126, 12827 (2004);<br></p>

<p>Applications Trithiocyanuric acid (cas# 638-16-4) is a useful research chemical.<br></p>

<p>Applications A useful wittig reagent.<br></p>

<p>Applications 2-[(Dipropylamino)sulfonyl]benzoic Acid, is a building block used in various chemical synthesis.<br></p>

<p>Applications 3-Acetamidophenyl acetate<br></p>

<p>Applications N-(4-bromo-2-thienyl)-carbamic Acid 1,1-Dimethylethyl Ester, is an intermediate for the synthesis of bicyclic inhibitors of ROCK protein kinsae.<br>References Hahmann, C. et al.: Cell. Mol. Life Sci., 67, 171 (2010);<br></p>

<p>Applications Methyl 4-Bromophenylacetate (cas# 41841-16-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(prop-2-ynyloxy)propanoic acid (cas# 134126-59-3) is a useful research chemical.<br></p>

<p>Applications 5-Amino-2-bromobenzoic acid (cas# 2840-02-0) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-(Dimethoxyphosphoryl)acetic acid<br></p>

<p>Applications Methyl 1-formylcyclopropane-1-carboxylate, is a building block used in the synthesis of chemical compounds.<br></p>

<p>Applications 5-Bromopentylboronic Acid<br></p>

<p>Applications 4-fluorobutanoic acid (cas# 462-23-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (2,3,4-Trimethoxyphenyl)boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer<br>References Hutschenreuter, T. et al.: J. Enz. Inhib. Med. Chem., 19, 17 (2004);<br></p>

<p>Applications 6-Hydrazinonicotinic acid<br></p>

<p>Stability Light Sensitive<br>Applications Ethyl 1-Bromocyclobutanecarboxylate is a reactant in the preparation of aroylindole-substituted phenoxyacetic acid derivatives, which has PPARγ and PPARα agonist activity, pharmacokinetics, and glucose and triglyceride lowering properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, W., et al.: J. Med. Chem., 52, 14 (2009)<br></p>

<p>Applications Methyl Chlorooxoacetate is used as a reagent in organic synthesis of several compounds including that of coumarin-based probes which fluoresce in response to detection of Pi in cell culture and Caenorhabditis elegans. Also used in the synthesis of phenanthrene β-diketo acids which is being studied as potential HIV-1 integrase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, H., et al.: Dyes Pigments, 120, 293 (2015); Sharma, H., et al.: Bioorg. Med. Chem. Lett., 23, 6146 (2013);<br></p>

<p>Applications (2S)-2-Ethyl-ester-isocyanato-propanoic acid is used as a reagent in synthetic chemical processes.<br>References Burger, Klaus., et al.: Liebigs Annalen der Chemie. 4, 407-413(1994);<br></p>

<p>Applications 2-amino-3-hydroxy-3-phenylpropanoic acid (cas# 7695-56-9) is a useful research chemical.<br></p>

<p>Applications 2-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid (cas# 13193-24-3) is a useful research chemical.<br></p>

<p>Applications Dibenzothiophene-2-boronic acid is a useful reagent for organic synthesis and other chemical processes.<br>References Duncton, M. A. J., et al.: Org. Lett., 10, 3259 (2008)<br></p>

<p>Applications 2-Pyridylphosphonic Acid is used as ligand in the hydrothermal preparation of copper(II)-lanthanide(III) and zinc(II)-lanthanide(III) pyridylphosphonate coordination polymers.<br>References Ma, Y., et al.: Chem. Eur. J., 13, 4759 (2007);<br></p>

<p>Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.<br>References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)<br></p>

<p>Applications 5-(aminomethyl)-2-furoic acid hydrochloride (cas# 934-65-6) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 3-Hydroxy-5-nitrobenzoic acid<br></p>

<p>Applications Hexahydro-4-oxo-1(2H)-azocinecarboxylic Acid 1,1-Dimethylethyl Ester is a chemical reagent used in organic synthesis.<br></p>

<p>Applications Used in the preparatiom of esters of 6-aminohexanoic acid as antibacterial agents. EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo xy peptidase, plasmin, and plasminogen activator.<br>References Dolezal, P., et al.: Pharm. Res., 10, 1015 (1993), Vavrova, K., et al.: Curr. Med. Chem., 12, 2273 (2005), Holas, T., et al.: Bioorg. Med. Chem., 14, 7671 (2006),<br></p>

<p>Applications Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.<br>References Ebeling, P., et al.: Lancet, 343, 1479 (1994); Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994); Ramachary, D.B., et al.: RSC Advances, 3, 13497-13506 (2013); Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977);<br></p>

<p>Applications 2-(Aminosulfonyl)benzoic Acid can be used as reactant/reagent in synthesis and pharmacological activity of γ-(phenyloxamido)- and γ-(phenylsulfonyloxamido)butanoic acids.<br>References Georgiyants, V. A., et al.: Farmatsevtichnii Zhurnal, 2, 34 (2010);<br></p>

<p>Applications Dihydroxyfumaric Acid Dimethyl Ester is used in the reactions involving of β-sheet formation.<br>References Kemp, D. et al.: J. Org. Chem., 55, 4650 (1990);<br></p>

<p>Ferroceneacetic acid is a compound that has been shown to have chemiluminescent properties. It is a potent reductant and oxidant, which means that it can reduce or oxidize other compounds. Ferroceneacetic acid is also an active enzyme, and its redox potential changes depending on the concentration of ferrocene in the solution. Ferroceneacetic acid can be used as a model system for analytical chemistry and electrochemistry.</p>

<p>7-Aminoheptanoic acid is a fatty acid that contains a hydroxyl group on the seventh carbon of its chain. This compound has been shown to bind to and activate the receptor GPR120. It is also used in the synthesis of pharmaceuticals, such as anti-inflammatory agents, and in analytical methods for detecting peptides. 7-Aminoheptanoic acid can be synthesized by reacting hydrochloric acid with an amine or amide, followed by reaction with an ester hydrochloride. The compound can be purified using preparative high performance liquid chromatography (HPLC).</p>

<p>Please enquire for more information about 5-(5-Chloro-1-methyl-1H-benzimidazol-2-yl)pentanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is an antimicrobial agent that inhibits bacterial growth by binding to the penicillin binding protein (PBP), which prevents the synthesis of peptidoglycan. This drug has shown effectiveness against gram positive bacteria, including aerobacter aerogenes, as well as infectious diseases in wastewater treatment plants. It has also been demonstrated to be effective in experimental models of infection due to high resistance and cell signaling pathways. The reaction solution was analyzed by plasma mass spectrometry.</p>

<p>6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties.</p>

<p>Please enquire for more information about 1-[2-(5-Methyl-1H-indol-3-yl)ethyl]-5-oxopyrrolidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (4-Chloro-3-(methoxycarbonyl)phenyl)boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Oxazepam acetate is a chiral drug that has enantiomeric forms. Oxazepam acetate is converted to the corresponding lorazepam by hydrolysis of the acetate ester group. This drug is an analytical method for determining the concentration of oxazepam in human serum and rat liver microsomes. It also has a stereoselective effect on nucleophilic attack, which means it only reacts with one of two possible sites in the molecule. Oxazepam acetate can be used to treat insomnia, anxiety, and seizure disorders.</p>

<p>3,5-Difluoromandelic acid is a biomolecule that is synthesized in the laboratory. It has been shown to have anti-cancer properties by inhibiting the formation of amyloid plaques and inhibiting γ-secretase, which are substances involved in the development of Alzheimer's disease. 3,5-Difluoromandelic acid has been shown to be more potent than other ligands in its class with respect to inhibition of γ-secretase activity. This molecule also shows stereospecificity for the L- and D-isomers of lactam substrates. 3,5-Difluoromandelic acid may be used as a potential lead for development of new drugs for treatment of Alzheimer's disease.</p>

<p>5-Hexynoic acid is a chemical compound that has been shown to have anticancer properties. The mechanism of action is not fully understood, but it may be due to its ability to inhibit an enzyme called irreversible acetylcholinesterase, which is involved in the production of several pro-inflammatory mediators. 5-Hexynoic acid has also been shown to inhibit the growth of prostate cancer cells and can be used as a therapeutic agent for prostate cancer. It is synthesized by plants and some microorganisms, although it is not found in humans. 5-Hexynoic acid can be produced from conjugates with glutamic acid or oxalyl chloride in an acidic environment.</p>

<p>Please enquire for more information about 20-Dehydro cholesterol 3-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-(Bromomethyl)benzoic acid is a quaternary ammonium salt that has been shown to be an ampk activator. It has been used in the synthesis of mesoporous materials and for the synthesis of sulfoxides, oxindoles, and carboxylic acids. 3-(Bromomethyl)benzoic acid has also been used as a calibrant for nonlinear regression analysis, due to its conformational properties.</p>

<p>Eltrombopag olamine is an orally active drug that belongs to the class of thiazolidinones. It has been used for the treatment of thrombocytopenia in patients with chronic liver disease and myelodysplastic syndrome. Eltrombopag olamine inhibits platelet aggregation by binding to glycoprotein IIb/IIIa receptors on the surface of platelets. The drug is a prodrug that is metabolized in vivo to its active form, eltrombopag. This conversion is catalysed by CYP3A4 and CYP2D6 enzymes and can be inhibited by drugs that inhibit these enzymes, such as trifluoroacetic acid and hydroxyl group-containing compounds. Eltrombopag olamine binds to erythrocytes, which may be due to its ability to form intramolecular hydrogen bonds with nitrogen atoms. The synthesis of elt</p>

<p>Ethyl 1,2-dimethyl-5-hydroxyindole-3-carboxylate (EDMC) is an implantable drug that is used to treat hypertension. It is a diuretic that can be taken orally or injected. EDMC works by reducing the amount of urea nitrogen in the blood and increasing the amount of chlorine atom in the urine. This leads to an increase in active substances such as malonic acid and a decrease in arthropoda. EDMC has been shown to have antihypertensive activity due to its ability to lower diastolic and systolic pressure. The molecule also contains hydroxyl group and aldehyde groups that are analyzed by analytical chemistry.</p>

<p>Please enquire for more information about 6-(Methoxycarbonyl)spiro[3.3]heptane-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Boc-(2R,5S)-5-phenylpyrrolidine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(2-Nitrobenzylidene)-3-oxobutanoic acid, methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hydantoin-5-acetic acid is a molecule that has been studied for its potential use in the stabilization of polymers and plastics. It has shown antibacterial activity against certain bacterial strains including Escherichia coli and Staphylococcus aureus. The molecule has the ability to coordinate with metal ions such as copper, zinc, and iron. The protonation state of the molecule is dependent on the pH of the environment. Hydantoin-5-acetic acid can exist in two tautomeric forms: hydantoin or 5-hydantoin. Hydantoin-5-acetic acid can be used to determine the concentration of hydrogen in proteins through chromatographic methods. This molecule also has Langmuir adsorption isotherm properties, which give it potential for use in supramolecular structures.</p>

<p>Benzyl bromoacetate is a bicyclic heterocycle that is metabolized by the enzyme benzyl alcohol dehydrogenase. The resulting metabolites are then converted to methyl benzoate and benzyl alcohol. It has been shown to inhibit prostate cancer cells and basic fibroblasts, which may be due to its ability to inhibit enzymes involved in fatty acid synthesis. Benzyl bromoacetate also has therapeutic effects on autoimmune diseases such as bowel disease, which may be due to its ability to reduce inflammation and suppress the immune system.</p>

<p>Please enquire for more information about 4-Aminobicyclo[2.2.2]octane-1-carboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-[(2S,3S,4S)-3-Formyl-5-Methoxycarbonyl-2-Methyl-3,4-Dihydro-2H-Pyran-4-Yl]Acetic Acid (PCA) is a natural phenolic compound that is found in olive oil. PCA has been shown to possess antioxidant and antiinflammatory properties. It also has minimal toxicity, with no adverse effects on the liver or kidney. PCA is metabolized by hydrolysis to form hydroxytyrosol and tyrosol. Hydroxytyrosol can be further metabolized to produce the aglycon 2-[(2S,3S,4S)-3-(acetyloxy)-5-(hydroxymethyl)oxolan-4-yl]acetic acid (OHA). OHA is an intermediate in the biosynthesis of erythromycin and other macrolide antibiotics such as</p>

<p>Please enquire for more information about Methyl 1H-imidazole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cell-penetrating peptide derived from the third helix of the Antennapedia protein homeodomain.  Penetratin also shows antimicrobial and antifungal activity.</p>

<p>Please enquire for more information about Chloroacetic Acid-13C2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2,3,3-Trimethyl-2-norbornyl isothiocyanic acid ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Bromocrotonic acid is a 3-mercaptopropionic acid (3-MPA) derivative. It inhibits the enzyme carnitine acyltransferase, which is involved in the uptake of fatty acids into mitochondria and their subsequent β-oxidation. This leads to an accumulation of fatty acids in the cytosol, which can inhibit insulin-stimulated glucose uptake and protein synthesis. 4-Bromocrotonic acid also inhibits glut1, an amp-activated protein kinase enzyme that plays a key role in cellular metabolism, leading to irreversible inhibition. 4-Bromocrotonic acid is used for analytical purposes as it is a good substrate for mitochondrial enzymes.</p>

<p>Please enquire for more information about 1-(4-Bromophenyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about L-Pyroglutamic acid pentachlorophenyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 1H-pyrrolo[2,3-b]pyridine-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-(4-Hydroxymethyl-3-methoxyphenoxy)-butyric acid (HMPA) is a synthetic compound that is used in the production of butyric acid. It is also used as a reagent in the preparation of enzymes and enzyme preparations, such as serine proteases. HMPA has been used as an intermediate in the synthesis of ribulose, which is a sugar molecule found in plants. The structure of this compound can be determined by FTIR spectroscopy and by X-ray crystallography. HMPA has been shown to have hydrogen bonding between its molecules, which may account for its stability. Hydrogen bonding accounts for the solidity of this compound and its resistance to heat and solvents.</p>

<p>Please enquire for more information about 1-tert-Butyl 2-methyl 2-methylpyrrolidine-1,2-dicarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-Chloro-2-(ethylsulfonyl)pyrimidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 5-bromo-1H-pyrazole-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>