Glycoscience

Applications Ligand used for the preparation of an affinity resin highly specific for glucosidase I purification. Glucosidase I is involved in the post-translational processing of N-linked glycoproteins.
References HettKamp, H., et al.: Eur. J. Biochem., 142, 85 (1984); Shailubhai, K., et al.: Biochem. J., 247, 555 (1987); Bause, E., et al.: FEBS, 278, 167 (1991)

Applications Used to inhibit breakdown of products by beta-hexosaminidase(s) when the culture medium is used as an enzyme source.
References Sasaki, K., et al.: Proc. Natl. Acad. Sci. USA, 94, 14294 (1997)

Stability Hygroscopic
Applications Trehalose 6-Phosphate Potassium Salt is an intermediate in the synthesis of D-(+)-Trehalose (T718750), a disaccharide composed of two α-glucose units. D-(+)-Trehalose is used in many processed foods as well as in biopharmaceutical monoclonal antibody formulations. When plants’ sugar levels are low, they reduce their investment in fatty acid synthesis. Trehalose 6-phoshate (T6P) regulates oil synthesis in plants. (Chem. and Eng. News p. 9 Oct. 1, (2018))
References Bosquillon, C. et al.: J. Cont. Rel., 99, 357 (2004); Arakawa, T. et al.: Adv. Drug Deliv. Rev., 46, 307 (2001); Singh, S.K. et al.: Pharmac. Res., 28, 873 (2011); Chem. and Eng. News p. 9 Oct. 1, (2018)

Applications Labelled L-Glucose is the enantiomer of D-Glucose (G595000), a naturally occurring carbohydrate used in an abundance of cellular processes. L-Glucose is a synthetic sugar used in the formation of L-Glucose Pentaacetate (G596510), a potential therapeutic agent regarding type II diabetes. In addition, L-glucose can be used as a colon cleansing agent for before a colonoscopy procedure.
References Malaisse, W. et al.: Int. J. Mol. Med., 2, 383 (1998); Raymer, G. et al.: Gastrointest. Endosc., 58, 30 (2003); Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009),

Applications Benzyl β-D-Glucopyranoside (cas# 4304-12-5) is a compound useful in organic synthesis.
References Yoshikawa, M., et al.: Chem. Pharm. Bull., 56, 1297 (2008), Takeda, Y., et al.: J. Nat. Med., 62, 476 (2008),

Applications Xylobiose is a disaccharide that can reduce the blood sugar and blood fat and inhibit the fat accumulation of diet-induced obese rats.
References Chen, H., et al.: Shipin Kexue, 35, 255 (2014)

Stability Hygroscopic
Applications N-Acetyllactosamine is used in the expansion of a multi-funcational natural scaffold for the study of structural space of the Galectin-1-Ligand interaction. Also, it is used to identify the impurity as an imidazoline ring structure.
References Bertleff-Zieschang, N., et al.: ChemBioChem, 18, 1477-1481 (2017); Duff, R. J., et al.: J. Chromatogr. A, 1501, 61-67 (2017);

Applications An anthocyanin responsible for red pigment in fruits and berries. It is an antioxidant, protecting the cell against damage from SOD.
References Riihinen, K., et al.: Food Chem., 110, 156 (2008), Khanizadeh, S., et al.: J. Food Comp. Anal., 21, 396 (2008), Viskelis, P., et al.: J. Food Sci., 74, C157 (2009), Comeskey, D., et al.: J. Agric. Food Chem., 57, 2035 (2009),

Applications (2S,3R,4R,5R,6R)-3-Acetamido-6-(acetoxymethyl)tetrahydro-2H-pyran-2,4,5-triyl Triacetate is used to synthesize selenium monosaccharide as metabolic biomarker.
References Deng, Shengyuan. et al., Faming Zhuanli Shenqing(2020);

Stability Hygroscopic
Applications γ-Cyclodextrin is used as nanomolecular encapsulation for drug delivery and pharmaceuticals. Used in the synthesis of unilamellar vesicles.
References Ikeda, A. et al.: Chem. Comm., 50, 1288 (2014); Gudmundsdottir, B. et al.: J. Ocular Pharm. Ther., 30, 35 (2014);

Applications Amino sugar found (as the N-acetyl derivative) in peptidoglycan, the main skeletal component of the bacterial cell wall. The N-acetyl derivative of muramic acid is an amino sugar that constitutes the peptidoglycan bacterial cell wall of Gram negative and Gram positive bacteria. Muramic acid is used as a chemical marker for the detection of bacterial contamination.
References Stout, J., et al.: Soil Biochem., 5, 1 (1981), Chantigny, M., et al.: Soil Biol. Biochem., 32, 1561 (2000), Martens, D., et al.: J. Environ. Qual., 29, 723 (2000),

Applications Intermediate in the preparation of Citicoline (C508050), a naturally occurring nucleotide.

Stability Hygroscopic
Applications A semi-synthetic analogue of Carminomycin with cytostatic activity.
References Mossman, T., et al.: J. Immunol. Methods, 65, 55 (1983), Janicke, R.U., et al.: J. Biol. Pharm., 273, 9357 (1998), Sidorova, T.A., et al.: J. Med. Chem., 21, 5330 (2002),

Applications Labelled D-Mannitol (M165000). D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Applications Iron Dextran is used for preventing and treating iron-deficiency anemia of newborn piglets.
References Amine, E., et al.: J. Agric. Food Chem., 20, 246 (1972), Caperna, T., et al.: J. Anim. Sci., 67, 654 (1989), Mukhopadhyay, C., et al.: J. Biol. Chem., 275, 21048 (2000),

Applications (2-Hydroxypropyl)-γ-cyclodextrin is used in the solubilization of macromolecules and in cell culture applications. Similar to β-Cyclodextrin (C987830), however can work with larger molecules.
References Motoyama, A. et al.: J. Pharmac. Biomed. Anal., 28, 97 (2002); Nakamura, N. et al. Biotechnol. Bioeng., 19, 87 (1977); Riddle, L. A. et al.: J. Chrom. Sci., 45, 330 (2007);

Applications Derivative of Neuraminic Acid
References Oetke, C., et al.: J. Biol. Chem., 277, 6688 (2002),

Applications A useful synthetic intermediate for carbohydrate chemistry.

Applications 4-Acetylphenyl β-D-Glucopyranoside (cas# 530-14-3) is a compound useful in organic synthesis.

Applications DL-Arabinose, is a building block of polysaccharide (CCPa-1) from fungus Coprinus comatus Gray, which has potential application as natural antitumor agent with immunomodulatory activity. Arabinose is also used as a culture medium for certain bacteria.
References Xiao-Gang, J., et al.: Int. J. Bio. Macromol., 58, 349 (2013);

Applications Scleroglucan is a natural polymer produced by fungi, especially those of the genus Sclerotium. Scleroglucan fluids have been used to trap and treat Cr(VI) in environmental applications.
References Brigand, G.: Industrial Gums (Third Edition), pp. 461 (1993); Pensini, E.; et al.: Colloids Surf., A, 559, 191 (2018);

Applications 5-Phospho-D-ribose 1-Diphosphate is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism.

Applications Impurity of β-cyclodextrin (C987830), a cyclic oligosaccharide produced from starch via enzymatic conversion.
References Johnson, M.D., et al.: J. Pharma. Sci., 83, 1142 (1994); Jain, A.C., et al.: Int. J. Pharma., 212, 177 (2001);

Applications Isotope labelled analog of α-D-Galactose 1-Phosphate, the phosphate conjugate of α-D-Galactose (G155260), a natural aldohexose which is ubiquitous in bacteria, plants, and animals, including human brains.
References Sang, J.L., et al.: J. Bacteriol., 190, 7932 (2008);

Applications 2-Acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-1,6-di-O-N-acetyl-α-D-muramic Acid (cas# 475502-13-7) is a compound useful in organic synthesis.

Applications (2S,​3R)​-2-​Methyl-1,​2,​3,​4-​butanetetrol is a secondary organic aerosol formed through photooxidation of isoprene. It was identified as a glucide in methanol extracts of Carum ajowan fruit.
References Claeys, M., et al.: Science, 303, 1173 (2004); Surratt, J., et al.: J. Physcial Chem. A., 110, 9665 (2006); Ishikawa, T., et al.: Chem. Pharm. Bull., 49, 840 (2001)

Applications D-Idose is a monosaccharide that is an important component of dermatan sulfate and heparan sulfate.
References Olsen, S.G., et al.: J. Biol. Chem., 264, 15982 (1989);

Applications D-Ribulose, a carbohydrate, is used in the production of D-Psicose, a new alternative sweetener.
References Gullapalli, P. et al.: Biosci. Beotechnol. Biochem., 71. 3048 (2007);

Applications A naturally occuring fibre found in the shells of shellfish. Used for the analysis of Chitinase.
References Skujins, J.J., et al.: Arch. Biochem. Biophys., 111, 358 (1965).