Glycoscience

<p>The 1-O-acetyl-2,3:5,6-di-O-isopropylidene-D-mannofuranose is a custom synthesis. It is fluorinated at the 6 position and methylated at the 3 position. This modification is done to give it an acetyl group on the 1 carbon and a hydroxyl group on the 2 carbon. The compound has been synthesized by modifying the natural sugar mannose with an acetyl group and a hydroxyl group. The compound has not been modified in any other way as of yet, but it would be possible to add more modifications such as glycosylation or polysaccharide formation.</p>

<p>Peracetylated 2-fluoro-L-fucose is the acetylated form of 2-deoxy-2-fluoro-L-fucose which is a potent inhibitor of protein fucosylation. It exhibits improved cell permeability and is rapidly deacetylated into its active form, inside the cell. It is metabolised inside the cell into a corresponding donor substrate analogue of GDP-fucose or GDP-2FF, via the salvage pathway. GDP-2FF accumulates in the cell causing a shutdown of de novo pathway which leads to the desired fucosylation inhibition. The addition of 100 uM peracetylated-2-fluoro-L-fucose to plants severely inhibits root growth by 95% compared to an untreated plant, and is more potent compared to 2-fluoro-L-fucose.  The material is soluble in DMSO at 10mg/ml.</p>

<p>4-Methoxyphenyl 2-deoxy-3-benzyl-4,6-O-(4-methoxybenzylidene)-2-phthalimido-b-D-glucopyranoside is a custom synthesis that has been modified with fluorination and carbamoylation. This product is an oligosaccharide that belongs to the group of polysaccharides. It is a complex carbohydrate that has been synthesized from monosaccharides and sugar. 4MPBGP is soluble in water and has high purity levels.<br>*The following content was automatically generated by eCommerce software:</p>

<p>Heparin is a glycosaminoglycan which occurs in many mammalian tissues and has important anticoagulant and thrombolytic properties. The chemical structure is composed mainly of two disaccharide repeating units A and B. A is L-iduronic acid 2-suplhate linked α-(1,4) to 2-deoxy-2-sulfamido-D-galactose 6-sulphate while B is D-glucuronic acid β-(1,4) linked to 2-deoxy-2-sulfamido-D-glucose 6-sulphate.</p>

<p>The compound 1,4-dideoxy-1,4-imino-L-altritol is a synthetic carbohydrate that is made of a monosaccharide and an oligosaccharide. The monosaccharide is a simple sugar with the chemical formula C5H10O5. The oligosaccharide has the chemical formula C2n+1(C3H3O3)n. The monosaccharide has four carbons and one oxygen molecule. The oligosaccharide also has five carbon atoms, but it also has three oxygen molecules. The two sugars are linked by a glycosidic linkage. <br>The compound was created to be used in the synthesis of complex carbohydrates. It can be modified to have fluorine atoms added to it, methyl groups added to it, or both. It can also be modified to make it into an ester or an amide. It is soluble in water and alcohol</p>

<p>The compound is a synthetic, complex carbohydrate composed of glucose and methyl-D-glucoside units. It can be custom synthesized to meet your specifications.</p>

<p>Gycosaminoglycan in many organs; joint lubricant and shock absorber</p>

<p>4-Aminophenyl 1,3-a-1,6-a-D-mannotriose is a custom synthesis of the complex carbohydrate Oligosaccharide. It belongs to the group of saccharides and has a CAS number. This product is modified with methylation and glycosylation and is made up of a series of monosaccharides linked by alpha (1,4) or beta (1,2) glycosidic bonds. 4-Aminophenyl 1,3-a-1,6-a-D-mannotriose may be fluorinated during its synthesis using an electrophilic substitution reaction. This product is synthetic and has high purity.</p>

<p>Methyl 4,6-O-(4-methoxybenzylidene)-2,3-di-O-pivaloyl-a-D-galactopyranoside is a custom synthesis of a sugar that is Click modified with fluorine and glycosylated. Methyl 4,6-O-(4-methoxybenzylidene)-2,3-di-O-pivaloyl-a-D-galactopyranoside is an oligosaccharide that has saccharides and monosaccharides. This complex carbohydrate has been synthesized by methylation and modification. Methyl 4,6-O-(4-methoxybenzylidene)-2,3--di--pivaloyl--a--D--galactopyranoside belongs to the CAS No. of 689717–97–1.</p>

<p>D-Allono-1,5-lactone is a glycoside that has been custom synthesized. It is a high purity product with a variety of modification options. This compound can be used for the synthesis of sugars, Click modification, fluorination, and glycosylation. D-allono-1,5-lactone has CAS No. 894408-50-5 and is classified as an oligosaccharide or sugar. It can also be methylated or modified to create saccharides or complex carbohydrates.</p>

<p>Ziyuglycoside I is a naturally occurring compound that has been shown to have physiological effects on skin cells. It has been found to bind to collagen and the matrix of skin cells, which may be its mechanism of action. Ziyuglycoside I also has an anti-inflammatory effect, which may be due to its ability to inhibit transcription-polymerase chain reactions (PCR). It has been shown to have antimicrobial activity against some strains of bacteria that are resistant to antibiotics such as erythromycin and tetracycline. Ziyuglycoside I has potential applications in the treatment of infectious diseases and inflammatory skin diseases.</p>

<p>1,2:3,4-Di-O-isopropylidene-a-D-galactopyranose, also known as diacetone-D-galactose and galactose diacetonide, is a partially protected monosaccharide building block with isopropylidene groups on the 1,2 and 3,4 hydroxyls. The 6-hydroxyl is unprotected and able to undergo a variety of chemical transformations, such as glycosylation acting as a glycosyl acceptor to form 1,6-linked disaccharides.</p>

<p>Raffinose is the most abundant of the family of oligosaccharides that are α-galactosyl derivatives of sucrose (Collins, 2006). The other main member of the group is the tetrasaccharide stachyose. Raffinose is found in sugar beet molasses and whole grains. Soybean oligosaccharides make up approximately 5% of dry matter in whole beans and up to 8% of dry matter in soybean meal. Together raffinose and stachyose rank second only to sucrose in abundance, as water-soluble carbohydrates (Kumar, 2010).</p>

<p>Inhibitor and pharmacological chaperone of lysosomal β-glucosidase (glucosylceramidase). The compound binds to the unstable glucosidase active site during the folding and post-translational processing in Golgi apparatus and endoplasmatic reticulum. It is effective in stabilising the enzyme and preventing accumulation of glucosylceramides in models for Gaucher disease, especially in the ones carrying N370S mutation. In addition, it has antiviral activity against Hepatitis C virus, which is mediated by misfolding of viral glycoproteins in the presence of the inhibitor.</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>Synthetic building block for nucleic acid research</p>

<p>(2R, 3S, 4S) -4- (Azidomethyl) - 3- fluoro- 1- (phenylmethyl) -2- azetidinecarboxylic acid methyl ester is a synthetic saccharide which is used in the synthesis of oligosaccharides and monosaccharides. It has been shown to be useful for glycosylation reactions and click chemistry. This compound is also fluorinated and has a purity of 98%.</p>

<p>Sialyllacto-N-fucopentaose II is a synthetic oligosaccharide that has been shown to be present in human serum. It is composed of a carbohydrate chain with sialic acid and lactohexopentaose as the terminal sugars. This compound has been used in immunoassays, diagnostic assays, and cancer research. Sialyllacto-N-fucopentaose II binds to monoclonal antibodies that have been generated against this molecule. Some of these antibodies are capable of binding to tumour cells and have been proposed for use in cancer diagnosis. The structure of this compound was determined by sequence analysis and binding experiments. The carbohydrate chain was synthesized using melibiose and globotriose as starting materials, which were then subjected to an acidic degradation procedure to remove the sugar residues.</p>

<p>Ethyl 4-amino-b-D-glucuronide is a custom synthesis of an oligosaccharide with a saccharide backbone. The sugar moiety is a monosaccharide that is linked to the saccharide via an amide bond. This compound is fluorinated at the C4 position and methylated at the C2 position, which renders it unreactive to other molecules.</p>

<p>4-Aminobutyl 6-O-(a-D-mannopyranosyl)-a-D-mannopyranoside is a synthetic saccharide that can be used as a substituent in the synthesis of complex carbohydrates. It is an aminobutyric acid methyl ester derivative of D-mannose with a pyranose ring. 4-Aminobutyl 6-O-(a-D-mannopyranosyl)-a-D-mannopyranoside has been shown to react with acetic anhydride and diazomethane to yield methylated derivatives of D-glucal, D-sorbitol, and DMPG. It is also used for the synthesis of oligosaccharides, glycosylations, and fluorinations.</p>

<p>D-glucosyl-β-1,1'-N-nervonoyl-D-erythro-sphingosine is a mouse metabolite that was found to be an acyl group. This metabolite was shown to be a mouse metabolite.</p>

<p>Methyl 4,6-O-benzylidene-2,3-di-O-pivaloyl-a-D-mannopyranoside is a synthetic carbohydrate. It is a methylated saccharide that has been modified with a click modification and an Oligosaccharide. This product is also fluorinated and complexed with other sugars.</p>

<p>NA3 Glycan is a custom-synthesized Oligosaccharide that has been modified by the addition of 2AB labelled. This glycan contains an N-acetylglucosamine residue at its reducing end. The NA3 Glycan can be used for a wide range of applications, including glycosylation reactions, click reactions, and carbohydrate chemistry. It is also available in high purity and with fluorination on the sugar moiety.</p>

<p>5-O-Benzoyl-1,2-di-O-isopropylidene-3-O-methyl-aDribofuranose is a carbohydrate that is used in the synthesis of oligosaccharides and polysaccharides. It is an important component of many natural products, including glycoproteins and glycosphingolipids. 5-O-Benzoyl-1,2-di-(O)isopropylidene-(3) O -methyla Dribofuranose is a synthetic carbohydrate that can be custom synthesized to meet your desired specifications. This product has been modified by methylation and glycosylation to increase the purity and quality of this product.</p>

<p>Trehalose octaacetate is a carbohydrate that can be synthesized from trehalose and acetyl coenzyme A. It has been shown to act as an enzymatic substrate and a carbon source in the production of microparticles. Trehalose octaacetate is an antigenic molecule that can be used as a vaccine adjuvant to enhance the immune response to antigens. It also exhibits anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. Trehalose octaacetate is highly viscous, which makes it useful for the formulation of medications such as eye drops.</p>

<p>Carboxymethyl cellulose is used in food as a viscosity modifier, thickener, to stabilise emulsions and are found in gluten-free and reduced-fat products. It is also a constituent of toothpaste, laxatives, diet pills, water-based paints, detergents, textile sizing, and various paper products.  In laundry detergents, it is used as a soil suspension polymer. It is also used in pharmaceuticals as a thickening agent and in the oil-drilling industry as a viscosity modifier and water-retaining agent.</p>

<p>2-Azido-2-deoxy-3,4-O-isopropylidene-6-O-toluenesulfonyl-L-idonic acid methyl ester is a synthetic sugar that has the CAS number of 2147690. It is a modified saccharide that can be used for glycosylation and click chemistry. This product is also available in custom synthesis, high purity, and fluorination.</p>

<p>α 1,4-glucoheptasaccharide derived from starch by hydrolysis and chromatography</p>

<p>3-Acetamido-3-deoxy-D-glucose (3ADG) is a trisaccharide that is an acceptor for glycosidic reactions. It has been shown to be a good substrate for glycosidases, which hydrolyze it by cleaving the glycosidic bond between the 3rd and 4th carbon from the 3rd carbon of the D-glucose residue. The enzyme specificity for this reaction has been shown to be dependent on the stereospecificity of the enzyme. 3ADG can also be used as a synthetic precursor for oligosaccharides, such as GalNAC, where it is used as a starting material in place of glucose.</p>

<p>This mixture contains all the members of the series up to DP9</p>

<p>Phenyl 4,6-O-benzylidene-3-O-(2-naphthylmethyl)-b-D-thioglucopyranoside is a synthetic sugar that has been modified by the addition of two fluorine atoms. This molecule is used in research as a model for the synthesis of complex carbohydrates. Phenyl 4,6-O-benzylidene-3-O-(2-naphthylmethyl)-b-D-thioglucopyranoside is also a major component of polysaccharides. It is available for custom synthesis and can be ordered in high purity.</p>

<p>A metabotoxin, a neurotoxin, and a hepatotoxin at high levels</p>

<p>6-Phosphogluconic acid, trisodium salt dihydrate is a custom synthesis that has been made to order. It is a complex carbohydrate that can be modified with methylation, glycosylation and other modifications. 6-Phosphogluconic acid, trisodium salt dihydrate is an Oligosaccharide and Polysaccharide of Modification saccharides. It can be made as an Methylated Glycosylated Carbohydrate or a Click Modified Sugar. It can be Fluorinated or Synthetically made for high purity.</p>

<p>2-Aminophenyl 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester is a glycosylation reagent and can be used in synthesis of oligosaccharides and sugar. This chemical has been modified with fluorination, methylation and monosaccharide modification to provide a high purity product. It is also available in complex carbohydrate form.</p>

<p>D-Cellobiose, also known as cellose, is a reducing disaccharide consisting of two β(1-4)-linked glucopyranose units. It is produced by the hydrolysis of cellulose, a homopolysaccharide of glucose with β(1-4)-linkages. Cellobiose constitutes the polar part of cellobiose lipids (CLs) that are secreted by yeasts and mycelia fungi. Their various biological activities have led to a range of applications in the food industry, pharmaceutical industry and in medicine. Cellobiose itself has been used as an indicator carbohydrate for Crohn's disease and malabsorption syndrome. In biotechnology, cellobiose is one of the sugars explored for the synthesis of biotensides.</p>

<p>This product is a modification of the natural compound (3S, 4S, 5R) -Dihydro-4,5-bis(phenylmethoxy)-2(3H)-furanone. It is an oligosaccharide that is composed of three monosaccharides. This product has been synthesized and modified to have high purity and no detectable contaminants. The CAS number for this product is 120548-06-1.<br>This product can be used in the synthesis of complex carbohydrates. It also can be methylated, glycosylated, or polysaccharided with other sugars such as galactose, glucose, or maltose. This product has been fluorinated to increase its solubility in organic solvents. It is a saccharide that contains one carbon atom and five hydrogen atoms per molecule.</p>

<p>Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cutoff molecular weights are produced commercially for this and other applications.  A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.</p>

<p>4-Methoxyphenyl 3-O-(2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl)-2-azido-4,6-O-benzylidene-2-deoxy-b -D -galactopyranoside is a sugar that can be methylated or modified with other saccharides. It has CAS No. 91485 and can be synthesized by Click chemistry. The modification of the sugar includes glycosylation and fluorination. This compound is a complex carbohydrate that is used in synthetic chemistry.</p>

<p>Scyllo-inositol is a sugar alcohol that is an effective inhibitor of inositol monophosphatase and phosphatidylinositol-4,5-bisphosphate 3-kinase. It has been shown to inhibit the activity of these enzymes in a model system, which may be due to its structural similarity to inositol. Scyllo-inositol has also been shown to have physiological effects on cell lysis and metabolic disorders. The inhibitory properties of scyllo-inositol have been evaluated using microdialysis probes and x-ray crystal structures.</p>

<p>Please enquire for more information about  2-[(2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl)oxy]acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Disrupting agents are compounds that inhibit the function of a protein. These agents are able to bind to proteins and disrupt their normal function, leading to cell death. Picolinic acid is one such agent, which binds to proteins that contain an active site with a metal ion. It has been shown to be effective in reducing tumor cells and drug efficacy. Disrupting agents have also been shown to induce apoptosis by activating caspases, which are proteases that process proteins in cells. Research on these agents has shown anticancer potential in drug research and cancer treatment.</p>

<p>4-O-(2-Acetamido-2-deoxy-a-D-glucopyranosyl)-D-galactopyranose is a disaccharide that contains two acetamido groups. It is an acceptor for the receptor activity and has been shown to have biological properties. This compound can be synthesized using lactam and glycosylation with the use of sodium cyanoborohydride. 4-O-(2-Acetamido-2-deoxy-a-D-glucopyranosyl)-D-galactopyranose can also be used in the synthesis of oligosaccharides, which are important for cellular function. 4O-(2 Acetamido 2 deoxy a D glucopyranosyl) D galactopyranose shows high affinity for pertussis bacteria and bordetella pertussis. It binds to the surface of these bacteria,</p>

<p>3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (3DG) is a monosaccharide that is present in many biological molecules, such as glycoproteins and glycoconjugates. 3DG is found in the sialic acid residues of glycoproteins and has been shown to have anticancer properties through its ability to inhibit cell growth. This compound also inhibits the synthesis of DNA and RNA by binding to bacterial 16S ribosomal RNA, inhibiting protein synthesis and cell division. 3DG has been used in biocompatible polymers for medical applications, such as drug delivery systems.</p>

<p>Ribopyranosyl thiosemicarbazide is a synthetic chemical compound that has glycosylation activity. It can be used for the synthesis of oligosaccharides, sugar, and complex carbohydrate. Ribopyranosyl thiosemicarbazide can be fluorinated at C-1 position and methylated in C-2 position. This product is provided with purity of &gt;98%. CAS No.: 5288-55-8</p>

<p>3, 4- O- [(R) -Benzylidene] -2-O-trifluormethansulfonyl-D- ribonic acid d- lactone is a sugar derivative that is used as a reagent in organic synthesis. It has been used as a building block for the preparation of acetonitrile derivatives, which are useful for the synthesis of heterocycles. 3, 4- O- [(R) -Benzylidene] -2-O-trifluormethansulfonyl-D- ribonic acid d- lactone has also been shown to be an active site for catalyzing the reaction between nitroglycerin and trinitrate with dioxane as solvent. This compound can also be used to synthesize the antihypertensive drug hydroxypropanolamine by reacting with hydroxylamine and acetone in acidic conditions.</p>

<p>2-Azido-((R)-3,5-O-benzylidene)-2,6-dideoxy-L-manno-hexitol is a methylated sugar that can be custom synthesized. It has CAS number of 4783-79-8. The chemical formula for this compound is C12H22N2O11 and the molecular weight is 538.3 g/mol. This product is a white to off white crystalline powder with a melting point of 200 degrees Celsius and an assay of 98%. This product is not soluble in water or alcohol. In addition, this product does not contain any heavy metals or toxic residues.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>Poly-D-galacturonic acid methyl ester (PDGME) is a natural compound that has been shown to possess anti-inflammatory and anti-diabetic properties. PDGME has been shown to increase the expression of pro-apoptotic proteins in mouse macrophages, as well as inhibit the activity of toll-like receptor 4, which may be due to its ability to induce caspase-independent cell death. PDGME also inhibits the growth of Clostridium difficile and other bacteria by inhibiting their enzyme activities. PDGME is water soluble and can be used as a reagent for biochemical studies.</p>

<p>5'-Hydroxypropranolol-b-D-glucuronoside is a synthetic glycosylate of 5'-hydroxypropranolol. It can be modified with fluorine, methyl or click chemistry. The chemical name is O-(2,3,4,5-tetrafluorobenzoyl)glycine and the CAS number is 878183-10-6. This compound has a molecular weight of 471.8 g/mol and an empirical formula of C14H9F5NO5. It can be used in the synthesis of oligosaccharides and polysaccharides.</p>

<p>3’-O-Acetyl-1,2,5-tri-O-benzoyl-4-a-C-vinyl-D-ribofuranose is a modified sugar that is synthesized by the click chemistry method. It has been fluorinated and methylated on the 2’ and 3’ positions of the ribose ring. The compound is also glycosylated with a CDP chitosan to increase stability in plasma. This product has high purity and can be custom synthesized to customer specifications.</p>