Antimicrobials

<p>Tri-O-benzyl FR 900098 is a chemical compound, often referenced in biochemical research contexts. It is a synthetic derivative that originates from complex chemical synthesis, involving multiple benzylation steps to modify the original molecular framework. This structural transformation lends the compound unique chemical properties.</p>

<p>28-Epirapamycin is a semisynthetic derivative of the macrolide antibiotic rapamycin, which is derived from the bacterium *Streptomyces hygroscopicus*. This compound functions primarily as an mTOR (mechanistic target of rapamycin) inhibitor. The mTOR pathway is crucial for regulating cell growth, proliferation, and survival by integrating signals from nutrients, growth factors, and cellular energy status.</p>

<p>Pyrenophorin is a polyketide metabolite, which is derived from certain fungi, specifically from the genus Pyrenophora. This compound demonstrates its biological efficacy through its unique mode of action as an antimicrobial agent, interfering with cellular processes in target microorganisms, leading to their inhibition or death.</p>

<p>Neticonazole hydrochloride is an antifungal agent, which is a synthetic imidazole derivative with potent antifungal properties. It is synthesized through a multi-step chemical process in a laboratory setting, designed to enhance its efficacy and stability. Its mode of action involves the inhibition of ergosterol synthesis, a critical component of fungal cell membranes. By hindering this pathway, Neticonazole hydrochloride compromises the integrity and function of the fungal cell membrane, ultimately leading to cell death.</p>

<p>Penciclovir diacetate is an antiviral compound, which is synthesized as a prodrug derivative of penciclovir. This compound originates from chemical modification processes designed to improve the pharmacokinetic properties of its active metabolite. Once administered, penciclovir diacetate undergoes in vivo conversion to penciclovir, an active nucleoside analog. The mode of action involves selective inhibition of viral DNA polymerase after being phosphorylated to its triphosphate form, thereby impeding viral DNA synthesis and replication.</p>

<p>Gramicidin is an antibiotic, which is derived from soil bacteria of the genus Bacillus, specifically Bacillus brevis. This polypeptide antibiotic exerts its antibacterial effects by disrupting the cell membranes of susceptible bacteria. Gramicidin forms channels in the phospholipid bilayers of bacterial cell membranes, leading to uncontrolled cation fluxes, which ultimately results in cell death. This mechanism is particularly effective against Gram-positive bacteria due to their specific cell wall structure.</p>

<p>Atherosperminine is an alkaloid compound, which is a bioactive chemical derived from plants. Specifically, it is sourced from members of the Lauraceae family, such as Atherosperma moschatum. This compound exhibits a range of pharmacological activities that are of significant interest to researchers. The mode of action of atherosperminine involves interactions with various biological pathways, potentially affecting physiological processes and exhibiting therapeutic effects.</p>

<p>Triadimenol-tert-butylhydroxy is a systemic fungicide, originating from synthetic chemical processes, characterized by its ability to inhibit fungal sterol biosynthesis. This sterol biosynthesis disruption occurs through the demethylation of lanosterol or 24-methylene dihydrolanosterol, which impedes the production of ergosterol, a crucial component in fungal cell membranes. The inhibition results in disrupted cell membrane integrity and impaired fungal growth, leading to effective control over a range of plant-pathogenic fungi.</p>

<p>(E)-Cefotaxime is a third-generation cephalosporin antibiotic, which is derived from the actinomycete mold Acremonium. Its mode of action involves inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death. This mechanism is highly effective against a wide range of Gram-positive and Gram-negative bacteria, including strains resistant to earlier cephalosporins and penicillins.</p>

<p>Acephate d3 is an isotopically labeled organophosphorus insecticide, which is a synthetic chemical compound used primarily for its insecticidal properties. It is derived by incorporating deuterium, a stable hydrogen isotope, into the molecular structure of acephate. The inclusion of deuterium isotopes is instrumental in tracing and studying the biochemical pathways and metabolic degradation of acephate within target organisms and ecosystems.</p>

<p>HBV-IN-4 is an antiviral compound that serves as a potent and selective inhibitor of hepatitis B virus (HBV). It is derived from chemical synthesis with a focus on targeting the viral replication machinery. The mode of action involves interrupting the HBV lifecycle by inhibiting the functioning of viral polymerase, thereby preventing the synthesis of viral DNA and subsequent viral propagation.</p>

<p>8-Methylpyrido[2,3-d]pyridazin-5(6H)-one is a heterocyclic compound used in the field of medicinal chemistry. This compound is synthesized through complex organic reactions involving pyridazine and pyridine derivatives. As a molecule, its primary mode of action involves interactions with specific biochemical pathways, potentially influencing enzymatic activity or receptor bindings, leading to modulation of biological activities.</p>

<p>Diclobutrazol is a plant growth regulator, a synthetic compound primarily derived from chemical synthesis methods. This compound acts by inhibiting the biosynthesis of gibberellins, which are plant hormones that regulate various aspects of growth and development. The inhibition of gibberellin biosynthesis results in reduced plant elongation, leading to more compact growth forms.</p>

<p>Pirlimycin HCl is an antibacterial product, which is a semi-synthetic derivative of the natural antibiotic lincomycin produced by Streptomyces lincolnensis. Its mode of action involves the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the elongation of peptide chains. This action is particularly effective against Gram-positive bacteria, including Staphylococcus and Streptococcus species.</p>

<p>Phenamacril is a synthetic fungicide, which is derived from chemical synthesis processes with a unique mode of action that targets fungal signaling pathways. It operates by inhibiting the myosin-5 ATPase activities within filamentous fungi, disrupting key cellular functions and effectively halting fungal growth.</p>

<p>Pseudomonic acid F is a naturally occurring secondary metabolite, which is derived from the bacterium *Pseudomonas fluorescens*. Its mode of action involves the inhibition of bacterial protein synthesis by targeting the bacterial isoleucyl-tRNA synthetase enzyme. This inhibition disrupts the addition of isoleucine to the growing polypeptide chain, effectively impeding bacterial growth and proliferation.</p>

<p>Validamycin E is an antifungal antibiotic, which is a secondary metabolite derived from the actinobacterium Streptomyces hygroscopicus. Its mode of action involves the inhibition of trehalase, an enzyme crucial for the hydrolysis of trehalose into glucose, disrupting essential energy pathways in fungi. By inhibiting trehalase, Validamycin E effectively interferes with the growth and development of fungal pathogens.</p>

<p>ABT-072 is a direct-acting antiviral (DAA) agent, specifically designed as an inhibitor of the hepatitis C virus (HCV) NS5B polymerase. This compound originates from advanced pharmaceutical research and development efforts aimed at targeting viral replication mechanisms. Being an NS5B polymerase inhibitor, ABT-072 functions by interfering with the viral RNA-dependent RNA polymerase. This enzyme plays a critical role in the replication cycle of the hepatitis C virus, facilitating the synthesis of new viral RNA strands. By inhibiting this enzyme, ABT-072 effectively halts viral replication.</p>

<p>Levomekol is a topical antibiotic ointment, which is a synthesized pharmaceutical product with antibacterial and anti-inflammatory properties. It contains chloramphenicol, a broad-spectrum antibiotic, and methyluracil, which promotes tissue repair and regeneration. The mode of action involves the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible microorganisms, effectively curbing bacterial growth and proliferation. Concurrently, methyluracil stimulates leukocyte activity and enhances the healing process by promoting cellular regeneration and collagen production.</p>

<p>CPFX2090 is a sophisticated software platform designed for advanced data analytics and visualization, which is developed by a team of computational scientists utilizing cutting-edge algorithms and machine learning techniques. It operates through a dynamic interface that enables automated data processing, multidimensional analysis, and real-time visualization. The platform's mode of action involves ingesting large datasets, performing parallel computations, and visualizing results with interactive graphical tools.</p>

<p>Please enquire for more information about ML303 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Vapendavir diphosphate is an antiviral compound, which is a synthesized small molecule with selective activity targeting picornaviruses. This compound is derived from rigorous medicinal chemistry efforts focusing on the inhibition of viral replication. Vapendavir diphosphate functions by binding to a specific site on the viral capsid, thereby inhibiting the uncoating process essential for viral RNA release into the host cell. This mode of action effectively prevents the virus from replicating within the host.</p>

<p>BRL 42715 is an antibacterial agent, which is a synthetic compound with a unique mechanism of action. This compound is derived from rational drug design aimed at targeting specific bacterial enzymes critical for cell wall synthesis. By irreversibly inhibiting these enzymes, BRL 42715 disrupts the bacterial cell wall formation, leading to cell lysis and death.</p>

<p>Anhydro erythromycin A is a semi-synthetic derivative of erythromycin A, which has been shown to be an effective inhibitor of bacterial growth, showing higher selectivity for this inhibition. It is a prodrug that is activated by acid catalysis and can be used as a substitute against methicillin-resistant staphylococcus. Anhydro erythromycin A was developed with the goal of increasing its stability and its potency against methicillin-resistant Staphylococcus aureus, which has been shown to be resistant to erythromycin.</p>

<p>Please enquire for more information about Omaciclovir including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rifamycin PR-3 is an antibiotic, which is derived from bacterial fermentation, specifically from the bacterium Amycolatopsis rifamycinica. It acts by inhibiting DNA-dependent RNA polymerase, thereby blocking RNA synthesis in susceptible bacteria. This inhibition disrupts protein synthesis, ultimately leading to bacterial cell death. Rifamycin PR-3 is primarily used for the treatment of various bacterial infections, particularly those caused by gram-positive bacteria and certain mycobacteria. Its application is crucial in managing diseases such as tuberculosis, where it targets the Mycobacterium tuberculosis. As a member of the rifamycin class of antibiotics, it is also explored for use in treating refractory cases and in combinations to prevent the development of resistance. This compound’s efficacy in penetrating phagocytic cells makes it an important player in addressing intracellular infections. Scientists continue to study its pharmacokinetics and potential for synergistic combinations, which may expand its utility in infectious disease therapy.</p>

<p>Thiostrepton is a thiopeptide antibiotic with action on bacterial protein synthesis by binding to the ribosome and is used for treating bacterial infections in veterinary medicine and research applications.</p>

<p>Ascomycin is an immunosuppressant macrolide lactone, which is derived from the soil bacterium *Streptomyces hygroscopicus*. It functions primarily by inhibiting the T-cell activation pathway. The mechanism involves binding to the immunophilin FKBP-12, forming a complex that inhibits the calcium-dependent phosphatase, calcineurin. This inhibition prevents the dephosphorylation and subsequent translocation of nuclear factor of activated T cells (NFAT), which is crucial for the transcription of interleukin-2 and other cytokines. Consequently, this suppresses the activation and proliferation of T-cells, which are essential components of the adaptive immune response.</p>

<p>Oligomycin is a macrolide antibiotic, which is derived from species of the bacterium Streptomyces. It acts as a potent inhibitor of the mitochondrial ATP synthase complex, specifically targeting the F₀ portion of the enzyme. This interference results in the blockage of proton translocation across the mitochondrial membrane, thereby preventing ATP synthesis. Due to this mode of action, Oligomycin is primarily utilized in biochemical research to study cellular respiration and energy metabolism. It serves as a valuable tool in elucidating the mechanisms of oxidative phosphorylation and the role of ATP in various cellular processes. In addition, its application extends to investigations on mitochondrial dysfunctions and the screening of mitochondrial-targeted drugs.</p>

<p>(2RS,4S)-2-[[(Phenylacetyl)amino]methyl]-5,5-dimethylthiazolidine-4-carboxylic acid, commonly referred to as penilloic acids, is a hydrolytic degradation product of benzylpenicillin. It is derived through the enzymatic or chemical cleavage of the β-lactam ring of benzylpenicillin, which is a classic β-lactam antibiotic.</p>

<p>Acepromazine hydrochloride is a phenothiazine derivative tranquilizer, which is synthesized chemically. Its mode of action is primarily through antagonism of dopamine receptors in the central nervous system, leading to a sedative effect. Additionally, it exerts peripheral actions, including alpha-adrenergic blockade and diminished release of hypothalamic and hypophyseal hormones, contributing to vasodilation and other physiological effects.</p>

<p>Dicloxacillin sodium salt monohydrate is a beta-lactam antibiotic with action on bacterial cell wall synthesis and is used for treating infections caused by penicillinase-producing bacteria.</p>

<p>Mafoprazine is an experimental psychotropic drug, which is an organic compound synthetically derived from the azapirone family. It functions primarily as a serotonin receptor agonist, specifically targeting the 5-HT1A receptors, while also exhibiting moderate affinity for dopamine and adrenergic receptors. This dual action on neurotransmitter systems is thought to contribute to its therapeutic effects.</p>

<p>Ionomycin is an ionophore compound with a mode of action that facilitates calcium ion transport across cell membranes. It is used in research to study calcium signaling and T-cell activation.</p>

<p>Dihydrostreptomycin sesquisulfate is an aminoglycoside antibiotic, which is derived from the bacterium Streptomyces griseus. Its mode of action involves binding to the 30S subunit of the bacterial ribosome, leading to the disruption of protein synthesis. This binding interferes with the initiation complex formation, causing misreading of mRNA and ultimately inhibiting bacterial growth.</p>

<p>3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine is a chemical compound classified as a heterocyclic organic compound, which is synthesized through chemical processes in the laboratory. This compound belongs to a novel class of molecules with potential pharmacological applications, particularly in the realm of infectious diseases. Its mode of action involves the inhibition of specific enzymatic pathways essential for the survival of certain pathogenic organisms, such as Plasmodium species responsible for malaria.</p>

<p>Anti-parasitic; pyruvate ferredoxin oxidoreductase inhibitor</p>

<p>Sulfamoyldapsone is a synthetic antimicrobial compound, which is derived from the dapsone family. Its source is primarily synthetic, designed through chemical modifications of the parent compound dapsone, a well-known antibacterial agent. The mode of action of sulfamoyldapsone involves the inhibition of bacterial folic acid synthesis. By targeting dihydropteroate synthase, an enzyme essential for the production of folic acid in microorganisms, the compound effectively interferes with bacterial growth and replication.</p>

<p>Lincomycin 2-palmitate hydrochloride is a semi-synthetic antibiotic, derived from the natural antibiotic lincomycin through chemical modification. It is sourced from fermentative processes involving the bacterium *Streptomyces lincolnensis*. The compound exerts its action by inhibiting protein synthesis in susceptible bacteria. This occurs through its binding to the 50S subunit of the bacterial ribosome, thereby hindering peptide chain elongation and ultimately arresting bacterial growth.</p>

<p>Please enquire for more information about Becliconazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Gatifloxacin related compound E is a chemical reference standard, which is often used in pharmaceutical and analytical chemistry research for the identification and quantification of impurities. It is generally synthesized or isolated as part of the quality control and validation process for the production of the antibiotic Gatifloxacin. The mode of action of this compound revolves around its structural similarity to Gatifloxacin, which allows it to serve as a benchmark to ensure the accuracy and reliability of high-performance liquid chromatography (HPLC) and other analytical techniques.</p>

<p>Piperacillin oxalylamide is an investigational antibiotic, which is a synthetic derivative of the widely used β-lactam antibiotic, piperacillin. Its development is rooted in the quest to combat β-lactamase-producing resistant bacterial strains, which are a growing threat in clinical settings. It operates by inhibiting bacterial cell wall synthesis, similar to other β-lactam antibiotics, but possesses a modified structure that enhances its resistance to enzymatic degradation by β-lactamases.</p>

<p>4-Epianhydrotetracycline is a chemical compound that is a derivative of tetracycline, a well-known antibiotic. It is primarily a byproduct arising from the chemical degradation of tetracycline antibiotics, occurring under acidic or basic conditions. The source of this compound is the structural transformation of tetracycline, resulting in an altered molecular configuration.</p>

<p>Imazethapyr-1-hydroxyethyl is a selective, systemic herbicide, which is synthesized through chemical processes. It functions primarily by inhibiting the acetohydroxyacid synthase (AHAS) enzyme, also known as acetolactate synthase (ALS). This enzyme is vital for the biosynthesis of branched-chain amino acids like valine, leucine, and isoleucine, which are essential for plant growth. By hindering this enzyme's action, Imazethapyr-1-hydroxyethyl effectively stunts the growth and development of susceptible plant species.</p>

<p>PF 1022A is a cyclooctadepsipeptide, which is a type of cyclic peptide composed of amino acids and hydroxy acids. It is derived from the fermentation products of the fungus *Mycelia sterilia*, a member of the *Rosellinia* genus. Its mode of action involves disrupting glutamate-gated chloride channels in parasitic nematodes, which leads to paralysis and eventual death of the parasite.</p>

<p>Indinavir monohydrate is an antiretroviral medication, which is a synthetic pharmaceutical compound, specifically a protease inhibitor, used in the treatment of HIV infection. It is derived from chemical synthesis processes that follow rigorous standards to produce a pharmacologically active compound. Indinavir functions by selectively inhibiting the HIV-1 protease enzyme, which is crucial for the viral replication cycle. By binding to the active site of the enzyme, indinavir prevents the cleavage of viral polypeptides, leading to the production of immature and non-infectious viral particles.</p>

<p>L-689502 is a synthetic compound that functions as a selective antagonist for neuropeptide Y1 receptors. It is derived from chemical synthesis processes specifically designed to target and modulate these receptors. As an antagonist, its primary mode of action involves binding to the neuropeptide Y1 receptors and inhibiting their activity, thereby blocking the effects of the naturally occurring ligand, neuropeptide Y (NPY).</p>

<p>Tebufenozide-hydroxymethyl is an insect growth regulator, which is synthesized chemically to function as an agonist of the molting hormone, ecdysone, in target pest species. It operates by mimicking the effects of ecdysone, leading to premature and lethal molting in lepidopteran larvae. This disruption in the developmental cycle of the insects effectively suppresses their population by preventing them from reaching maturity and reproducing.</p>

<p>Inducer of DNA strand breaks; glycopeptide antibiotic, anti-neoplastic</p>

<p>Atazanavir-d5 is an isotopically labeled variant of the antiretroviral drug Atazanavir, a non-peptidic HIV-1 protease inhibitor. It is synthesized using stable isotope labeling, specifically deuterium, which replaces five hydrogen atoms. The mechanism of action involves binding to the active site of the HIV-1 protease enzyme, a critical enzyme in the replication cycle of HIV, thereby preventing the cleavage of the viral gag-pol polyprotein precursors into the mature protein components of an infectious viral particle.</p>