Antimicrobials

<p>Potent antiviral against HCMV and Epstein-Barr virus (EBV)</p>

<p>Bromophos-methyl-oxon is an organophosphate insecticide and acaricide, which is a synthetic chemical derived from organophosphate compounds. It functions by inhibiting the activity of the enzyme acetylcholinesterase in target organisms. This inhibition leads to the accumulation of acetylcholine at nerve synapses, disrupting normal nerve function and ultimately resulting in the paralysis and death of pests.</p>

<p>Asukamycin is an antibiotic, which is a secondary metabolite derived from the bacterium *Streptomyces nodosus*. Its mode of action involves the inhibition of cell wall synthesis in susceptible bacteria by interfering with peptidoglycan polymerization, which is essential for maintaining bacterial cell integrity. Additionally, asukamycin exhibits the ability to interfere with the biosynthesis of important cellular components in certain pathogens, contributing to its antimicrobial efficacy.</p>

<p>Chaetoglobosin A is a mycotoxin, which is a secondary metabolite produced by the fungus Chaetomium globosum. This compound exhibits its mode of action by disrupting the cytoskeletal elements within cells, primarily affecting actin polymerization. This interference leads to alterations in cell morphology and can induce apoptosis in certain cell lines.</p>

<p>Pantoprazole-d3 is a stable isotope-labeled version of the proton pump inhibitor pantoprazole, which is derived synthetically for scientific research and analytical applications. Isotope labeling involves substituting hydrogen atoms with deuterium, resulting in Pantoprazole-d3 containing three deuterium atoms. This modification preserves the pharmacological profile of the parent compound while enabling precise tracking in biological studies through advanced spectroscopic techniques.</p>

<p>Phthivazid is an antibiotic, which is a synthetic derivative of isonicotinic acid hydrazide. It functions by inhibiting the synthesis of mycolic acids in the mycobacterium cell wall, which are essential components for the survival of the bacteria. This disruption in the cell wall synthesis results in bactericidal activity against Mycobacterium tuberculosis.</p>

<p>Trans-tetradecenyl acetate is a synthetic pheromone, which is an analog of a naturally occurring insect sex pheromone. It is derived from synthetic organic chemistry processes that aim to replicate the molecular structure of pheromones produced by insects. The mode of action involves mimicking the natural pheromone signals used by female insects to attract males. By dispersing trans-tetradecenyl acetate into the environment, it disrupts the mating communication between the sexes, leading to a reduction in successful mating events and, consequently, a decrease in pest population over time.</p>

<p>Duocarmycin SA is an antitumor antibiotic, which is derived from the natural products of Streptomyces bacteria. This compound exhibits its mode of action through the alkylation of DNA, specifically binding within the minor groove. The alkylation process preferentially targets adenine-thymine-rich regions, leading to irreversible DNA damage and subsequent inhibition of DNA replication. Such interaction results in the induction of apoptosis in rapidly dividing cells.</p>

<p>PSI-7409 is a novel antimicrobial compound, which is synthetically derived with a unique mechanism of action. This compound is engineered through a complex synthesis process ensuring high purity and efficacy. PSI-7409 exerts its effects by disrupting bacterial cell wall synthesis, leading to cell lysis and death. Its precise mode of interaction on the molecular level involves inhibition of key enzymatic pathways essential for peptidoglycan assembly, thereby compromising the structural integrity of bacterial cells.</p>

<p>Bromobutide-desbromo is a chemical compound that functions as a selective herbicide. It is derived from synthetic sources and is specifically formulated to interfere with photosynthesis in target plants. The mode of action of bromobutide-desbromo involves inhibiting photosystem II, a crucial component of the photosynthetic electron transport chain in plants. This inhibition disrupts the energy conversion process, leading to a decrease in ATP and NADPH production, which are essential for plant growth.</p>

<p>2,4,5,6-Tetrachlorophenol-13C6 is an isotopically labeled chemical compound, primarily used as a reference standard in analytical chemistry. This compound, derived from its non-labeled counterpart 2,4,5,6-tetrachlorophenol, is synthesized through the incorporation of carbon-13 isotopes. Its primary mode of action involves acting as a stable, traceable marker, facilitating accurate quantification and analysis of environmental samples, particularly in mass spectrometry.</p>

<p>Radicinol is a natural compound, which is a dihydroflavonol primarily sourced from plant origins. This compound is biosynthesized in specific plant species and extracted through meticulous biochemical processes to ensure its purity and efficacy. The mode of action of Radicinol involves the modulation of specific cellular pathways, conferring antioxidative and anti-inflammatory properties. It acts by scavenging free radicals and enhancing cellular resilience against oxidative stress.</p>

<p>Please enquire for more information about Egcg octaacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tolnifanide is a fungicidal product, which is a synthetic compound derived from chemical synthesis. It operates by interfering with the normal cellular function of fungi, inhibiting their growth and reproduction. This mode of action involves disrupting key processes within the fungal cells, rendering them unable to thrive in their host environment.</p>

<p>Lascufloxacin is a synthetic fluoroquinolone antibiotic, which is derived from chemical synthesis. Its mode of action involves inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication, transcription, repair, and recombination. By targeting these enzymes, lascufloxacin effectively hampers bacterial cell division and growth, leading to cell death. This mechanism specifically affects Gram-positive and Gram-negative bacterial strains, making it a versatile agent in antibacterial therapy.</p>

<p>Fluxapyroxad-N-desmethyl is a fungicidal metabolite, which is derived from the parent compound fluxapyroxad, a pyridine carboxamide fungicide. The source of this compound is through the biological or chemical transformation of fluxapyroxad, which involves demethylation. Its mode of action involves the inhibition of succinate dehydrogenase, an essential enzyme in the fungal pathogen's mitochondrial electron transport chain. This inhibition results in disruption of energy production within the fungal cells, ultimately leading to their death.</p>

<p>N-Biotinyl-12-aminododecanoyltobramycin amide is a synthetic bioconjugate, which is derived from the aminoglycoside antibiotic tobramycin. This compound is chemically modified by the addition of a biotin moiety linked through a 12-aminododecanoyl spacer. The source of this product is rooted in the conjugation of biotin to tobramycin, allowing for targeted delivery and potential hybrid applications in both therapeutic and diagnostic fields.</p>

<p>Ofloxacin methyl ester is a chemical compound, which is a derivative utilized in scientific research, particularly in the synthesis of ofloxacin-related compounds. It is a synthetic ester, derived from chemical synthesis involving ofloxacin, a fluoroquinolone antibiotic. The mode of action of ofloxacin methyl ester is based on its role as an intermediate compound. It facilitates the creation of active forms or analogs that can be tested for their pharmacological properties. Although not directly used as a therapeutic agent, it plays a crucial role in the development and modification of molecules for antibacterial applications.</p>

<p>Abacavir-d4 is a deuterium-labeled analogue of the antiretroviral medication Abacavir. It serves as a critical tool for pharmaceutical research and development. This isotopically labeled compound is synthesized by incorporating four deuterium atoms into the molecular structure of Abacavir, preserving the pharmacokinetic and pharmacodynamic properties of the original molecule while allowing for precise analytical quantification.</p>

<p>3'-N-Desmethyl-3'-N-formyl azithromycin is a semi-synthetic macrolide antibiotic, derived from the well-known azithromycin. It is created through structural modification, where the 3'-N-demethylated and 3'-N-formyl groups enhance its pharmacokinetic properties and potentially improve its antimicrobial efficacy.</p>

<p>Inhibitor of protein synthesis; streptogramin</p>

<p>Cenicriviroc sulfone is a small-molecule pharmaceutical compound, which is a synthetic product derived from medicinal chemistry optimization processes. It functions as a dual antagonist of the CCR2 and CCR5 receptors, which are chemokine receptors involved in inflammatory response and HIV entry, respectively. By blocking these receptors, Cenicriviroc sulfone inhibits the signaling pathways that lead to immune cell recruitment and inflammation.</p>

<p>Griseoluteic acid is a cyclic lipopeptide that inhibits bacterial growth by binding to the enzyme cyclase, which is involved in the production of cyclic AMP. Griseoluteic acid also inhibits the synthesis of rRNA (ribosomal RNA), which is required for protein synthesis. The compound has been shown to have a high degree of resistance against antibiotic-resistant strains and exhibits a low toxicity profile in vitro. Griseoluteic acid also has an inhibitory effect on hydrogen bonding interactions, which may be due to its ability to inhibit energy metabolism. This compound also exhibits anti-inflammatory properties and has been shown to have neurodevelopmental effects in animal models.</p>

<p>Triazoxide-desoxy is an investigational compound, which is a synthetic derivative of triazoxide, originating from pharmacological research aimed at modulating physiological pathways. This compound acts primarily by influencing ion channel activity at a cellular level, impacting the regulation of potassium channels which are crucial for maintaining cellular homeostasis and signaling.</p>

<p>Ceratotoxin A is a peptide toxin, which is derived from the venom of the female fruit fly *Ceratitis capitata*. This toxin is part of a group of antimicrobial peptides that play a crucial role in the innate immune response of the fly. Ceratotoxin A functions by integrating into the cell membranes of bacteria, leading to membrane disruption and subsequent bacterial cell death.</p>

<p>Carbovir is a nucleoside reverse transcriptase inhibitor (NRTI), which is derived from carbocyclic nucleosides. Its mode of action involves the selective inhibition of the reverse transcriptase enzyme, an essential component in the replication cycle of retroviruses, such as HIV. By incorporating into the viral DNA chain during synthesis, Carbovir effectively halts chain elongation, thereby impeding the virus's ability to proliferate.</p>

<p>Coumoxystrobin is a fungicide, which is a product of synthetic chemistry with a mode of action that involves the inhibition of mitochondrial respiration. Specifically, it disrupts the electron transport chain by binding to the Qo site in complex III, thereby preventing the transfer of electrons. This action halts ATP production, leading to the death of fungal cells.</p>

<p>Gentamicin C2 pentaacetate (2 : 1 Mixture of C2 and C2a) is an aminoglycoside class antibiotic derivative, primarily derived from the fermentation of Micromonospora species. This product is a semi-synthetic compound, combining two closely related gentamicin components, C2 and C2a, in a specified ratio. Its mode of action involves binding to the 30S subunit of the bacterial ribosome, which disrupts protein synthesis resulting in bactericidal activity against a wide spectrum of Gram-negative and some Gram-positive bacteria.</p>

<p>trans-Abacavir dihydrochloride is a synthetic compound classified as a nucleoside analog. It is derived from chemical synthesis and serves as a prodrug that is metabolized in the body to its active form, carbovir triphosphate. Its primary mode of action involves the inhibition of the HIV-1 reverse transcriptase enzyme. This inhibition is achieved through the incorporation of the active metabolite into viral DNA, resulting in chain termination and preventing viral replication.</p>

<p>Aureonitol is a fungal metabolite, which is sourced from specific species of fungi, primarily within the Aspergillus and Penicillium genera. This is a naturally occurring compound that functions as an antibiotic, disrupting the biosynthesis processes within certain microorganisms. It achieves this action by inhibiting key enzymes involved in cell wall formation or by interfering with nucleic acid pathways, thereby impeding the growth and proliferation of bacterial cells.</p>

<p>Licoflavone B is a naturally occurring flavonoid, which is primarily derived from the roots of licorice plants, such as Glycyrrhiza inflata. It functions as a bioactive compound with potential antioxidant and anti-inflammatory activities. The mode of action of Licoflavone B involves the scavenging of free radicals, modulation of signaling pathways, and inhibition of pro-inflammatory mediators. These biological activities render it valuable in research focused on chronic diseases and oxidative stress.</p>

<p>Fluhexafon is an innovative acaricide, which is derived from advanced chemical synthesis. Its mode of action involves disrupting critical biological processes in mites, specifically targeting nerve receptor pathways to inhibit their survival and reproduction. By interfering with the neurotransmission, it effectively reduces mite populations, ensuring healthier crops.</p>

<p>Acetophos is an organophosphate insecticide, which is a synthetic chemical compound derived from phosphoric acid. It functions by inhibiting acetylcholinesterase, an essential enzyme in the nervous systems of insects. This inhibition leads to the accumulation of acetylcholine, causing continuous nerve impulses that result in the paralysis and eventual death of the pest.</p>

<p>Napyradiomycin A is a secondary metabolite, classified as a type of antibiotic, which is derived from marine Streptomyces bacteria. This natural product is of considerable interest due to its unique biosynthetic origin, found specifically in marine ecosystems. Napyradiomycin A exhibits its mode of action primarily through the inhibition of bacterial RNA synthesis. This is achieved by interacting with bacterial enzymes, subsequently halting their reproductive and metabolic processes, which makes it a potent antibacterial agent.</p>

<p>SARS-CoV-IN-3 is a small-molecule inhibitor, which is derived through synthetic organic chemistry targeting SARS-CoV-2. It exhibits its mode of action by specifically inhibiting the viral RNA-dependent RNA polymerase (RdRp) enzyme. This enzyme is crucial for viral RNA synthesis, and by inhibiting its activity, SARS-CoV-IN-3 effectively suppresses viral replication within host cells.</p>

<p>Biotinyl tobramycin amide is a biotinylated form of the antibiotic tobramycin, which is derived from the actinobacterium Streptomyces tenebrarius. It features a tobramycin core, a potent aminoglycoside antibiotic, chemically linked to biotin. This modification allows for the specific attachment to avidin or streptavidin-labeled probes due to the strong biotin-streptavidin interaction, facilitating various labeling and detection techniques in research.</p>

<p>Anti-fungal; sterol 14α-demethylase inhibitor</p>

<p>Mecillinam is a beta-lactam antibiotic specifically designed for use in culture media. It is derived from the amidinopenicillin family, featuring a unique ability to interfere with bacterial cell wall synthesis. Its mode of action involves inhibiting penicillin-binding protein 2 (PBP2), an essential enzyme for cell wall elongation and maintenance in Gram-negative bacteria. This targeted inhibition results in the formation of spherical cells and subsequent cell lysis.</p>

<p>DSHS00884 is a CRISPR-associated enzyme, which is a type of gene-editing tool derived from bacterial immune systems. This enzyme functions as a molecular scissor that targets specific DNA sequences and introduces breaks or modifications at defined loci. The mode of action involves recognizing specific guide RNA sequences that direct the enzyme to complementary DNA sites where it executes precise edits. This precision stems from its ability to form base-pair interactions with the targeted DNA, ensuring minimal off-target effects.</p>

<p>Rifampicin is a drug that inhibits protein synthesis in bacteria and is used to treat tuberculosis. Rifampicin binds to the beta subunit of the bacterial RNA polymerase, inhibiting transcription and translation. It has been shown to inhibit the acetylcholine receptor function in rats, which may be related to its antituberculosis activity. Histopathological studies have shown that rifampicin inhibits the growth of human tumors in mice, including lung cancer, breast cancer, and leukemia. The drug is also being studied for its potential use in treating Alzheimer's disease. The pharmacokinetics and oral bioavailability of rifampicin have been studied and Rifampicin has been shown to be an effective anti-tuberculosis drug.</p>

<p>Lydicamycin is an antibacterial compound, which is a polyketide-derived antibiotic produced by the microorganism Streptomyces. This natural compound functions by inhibiting bacterial protein synthesis, effectively interrupting critical cellular processes within susceptible bacteria. The mode of action primarily focuses on binding to the bacterial ribosome, thereby disrupting protein production and inhibiting bacterial growth.</p>

<p>Please enquire for more information about Noracronycine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Thiamphenicol is a semisynthetic derivative of chloramphenicol with action on bacterial protein synthesis inhibition and is used for treating bacterial infections, particularly in veterinary medicine.</p>

<p>Furaprofen is a nonsteroidal anti-inflammatory drug (NSAID), which is a synthetic pharmaceutical compound derived from the carboxylic acid class. Its mode of action involves inhibiting the enzyme cyclooxygenase (COX), which plays a crucial role in the biosynthesis of pro-inflammatory prostaglandins. By blocking COX activity, Furaprofen reduces the formation of these signaling molecules, thereby alleviating inflammation and pain.</p>

<p>Gemifloxacin is an antibacterial agent primarily classified as a fluoroquinolone antibiotic, which is a synthetic compound derived from chemical processes in pharmaceutical manufacturing. Its mechanism of action involves the inhibition of key bacterial enzymes, namely DNA gyrase and topoisomerase IV. These enzymes are crucial for bacterial DNA replication, transcription, repair, and recombination. By obstructing these enzymes, Gemifloxacin effectively inhibits bacterial cell division and growth, leading to the eradication of susceptible bacterial strains.</p>

<p>Letrozole is a non-steroidal aromatase inhibitor, which is synthesized chemically. This product acts by inhibiting the aromatase enzyme, thus reducing estrogen production in the body. Estrogen plays a critical role in the proliferation of hormone-sensitive breast cancer cells, and by lowering its levels, Letrozole effectively impedes cancer growth.</p>

<p>AT-511 is an antiviral compound, which is derived from organic synthesis processes associated with the development of nucleotide analogs. It acts by targeting the RNA-dependent RNA polymerase, a crucial enzyme in the replication process of RNA viruses. By inhibiting this enzyme, AT-511 effectively halts viral replication, reducing the viral load within the host.</p>

<p>Tuberculosis inhibitor 3 is a synthesized chemical compound designed to target the Mycobacterium tuberculosis bacterium, which is the causative agent of tuberculosis. This inhibitor is derived through advanced chemical synthesis techniques, involving the modification of specific molecular structures to enhance its binding affinity and specificity toward the bacterial cellular targets.</p>

<p>Duocarmycin MA is a cytotoxic compound, which is a derivative of natural products isolated from bacteria of the Streptomyces genus. Its mode of action involves the alkylation of DNA, leading to the cleavage of the DNA helix and ultimately resulting in cell apoptosis. This process is highly selective for adenine-thymine rich regions, allowing it to precisely target and disrupt cancerous cells.</p>

<p>Sulconazole nitrate is an antifungal agent, which is a synthetic compound derived from imidazole. Its mode of action involves the inhibition of ergosterol synthesis, an essential component of fungal cell membranes, leading to increased membrane permeability and ultimately cell death.</p>