Flavonoids

<p>4',6,7-Trimethoxyisoflavone is a naturally occurring isoflavone, which is a type of phytoestrogen found in certain plants. This compound is generally derived from plant sources that are rich in isoflavones, such as soybeans and other legumes. Isoflavones like 4',6,7-Trimethoxyisoflavone are known to exhibit a range of biological activities due to their structural similarity to estrogens, allowing them to bind to estrogen receptors.</p>

<p>(S)-Equol is a non-steroidal estrogen, which is a metabolite produced by the gut microbiota from dietary isoflavones, specifically daidzein, found in soy and other legumes. It has high affinity for estrogen receptor beta, playing a significant role in modulating estrogenic activity without altering steroid hormone levels.</p>

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<p>Leucocyanidin polymer is an oligomeric flavonoid compound, which is primarily sourced from plants, particularly abundant in certain fruits, seeds, and barks. These naturally occurring polymers belong to a class of compounds known as proanthocyanidins, which are part of the larger flavonoid family.</p>

<p>Luteolin is a flavonoid compound, which is a naturally occurring substance found predominantly in various fruits, vegetables, and medicinal herbs. Its sources are diverse, including parsley, artichokes, celery, and chamomile tea, where it is accumulated as a secondary metabolite. The mode of action of luteolin primarily involves the inhibition of key enzymes and pathways that lead to oxidative stress and inflammation, including but not limited to the cyclooxygenase and lipoxygenase pathways. This inhibition results in its strong antioxidant and anti-inflammatory properties.</p>

<p>Tectoridin is a naturally occurring isoflavone glycoside, which is derived from the rhizomes of the Iris plant, particularly from Iris tectorum. This compound acts as a bioactive isoflavone that can undergo enzymatic hydrolysis to release tectorigenin, the aglycone form. Tectoridin and its metabolites are investigated for their pharmacological properties, which include antioxidant, anti-inflammatory, and anti-cancer activities.</p>

<p>5,4'-Dimethoxyflavanone is a flavonoid compound, which is a type of polyphenolic product ubiquitously found in various plant sources. These flavonoids are synthesized by plants as secondary metabolites, which aid in plant defense against herbivores and pathogens, and also contribute to the plant's coloration. The mode of action of 5,4'-Dimethoxyflavanone involves the modulation of oxidative stress and inflammation pathways. It achieves this by scavenging free radicals and inhibiting pro-inflammatory enzymes, thus providing a protective effect at the cellular level.</p>

<p>Vitexicarpin is a type of flavonoid compound, which is derived from plants in the Vitex genus, commonly known as the chaste tree. This naturally occurring bioactive compound acts primarily through the inhibition of various signaling pathways involved in inflammation and cancer progression. Its mechanism often targets pathways such as NF-kB and MAPK, which play crucial roles in inflammatory responses and cellular proliferation.</p>

<p>3,7,8,2',4'-Pentahydroxyflavone is a flavonoid compound, which is a type of polyphenolic secondary metabolite found in various plants. This compound is typically isolated from natural sources, including vegetables, fruits, and certain herbs. Its chemical structure, characterized by multiple hydroxyl groups, contributes to its potent antioxidant activity, allowing it to scavenge free radicals effectively.</p>

<p>Kaempferol-3-sophoroside-7-glucoside is a flavonoid glycoside, which is a type of bioactive compound commonly found in various plant species. It is typically isolated from plant sources known for high flavonoid content, such as vegetables, fruits, and certain medicinal herbs. The compound's mode of action is primarily characterized by its ability to engage in redox reactions, thereby exerting antioxidative effects. This antioxidative action is facilitated via the scavenging of free radicals and reactive oxygen species, contributing to its role in cellular protection.</p>

<p>Quercetin 3-α-L-rhamnoside is a flavonoid compound, which is a plant-derived product with rich biological activity. It is primarily sourced from various fruits and vegetables, where it occurs naturally as a glycoside. The mode of action involves its capability to modulate oxidative stress and inflammation through interactions with several cellular pathways, primarily by acting as an antioxidant and modulating enzyme activity related to reactive oxygen species.</p>

<p>Patulin is a mycotoxin, which is a toxic secondary metabolite produced by certain species of fungi, particularly those within the genera Penicillium, Aspergillus, and Byssochlamys. It is predominantly sourced from moldy fruits, especially apples and apple-derived products, where these fungi thrive and synthesize the compound. The mode of action of patulin involves disrupting cellular processes by forming covalent adducts with proteins and nucleic acids, ultimately leading to cellular damage and oxidative stress.</p>

<p>Scutellarin is a bioactive flavonoid compound, which is derived primarily from the plant Scutellaria baicalensis and other species within the Scutellaria genus. As a naturally occurring phytochemical, Scutellarin exerts its effects through multiple biological pathways, including antioxidant, anti-inflammatory, and anti-apoptotic activities.</p>

<p>7,2'-Dihydroxy-4',5'-methylenedioxyisoflavone is a naturally occurring isoflavone compound, which is typically isolated from various plant sources. This compound is a secondary metabolite, often found in plants known for their therapeutic properties. Isoflavones are well-recognized for their potential bioactivity, acting as phytoestrogens due to their structural similarity to estrogen.</p>

<p>Isosakuranetin is a flavonoid compound, which is derived from various plant sources, especially citrus fruits and other botanicals. Its mode of action involves modulating key signaling pathways, primarily through its antioxidant properties. These antioxidants scavenge free radicals, thereby mitigating oxidative stress and reducing cellular damage. This biochemical activity makes isosakuranetin a compound of interest in various fields related to health and disease prevention.</p>

<p>5,6,7-Trimethoxyflavone is a specialized flavonoid compound, which is derived from natural plant sources. This compound exists primarily in certain species of the plant kingdom, such as citrus fruits, where it is part of a group of polyphenolic compounds known for their diverse biological activities. Its structure is characterized by the presence of three methoxy groups at positions 5, 6, and 7 on the flavone backbone, contributing to its distinct biochemical properties.</p>

<p>7-Benzyloxy-2',4'-dimethoxyisoflavone is a synthetic isoflavone, which is a type of phenolic compound. Isoflavones are derived from plants, commonly found in soybeans and other legumes, and are often synthesized in laboratories for research and pharmaceutical purposes. These compounds are known for their structural similarity to estrogens and their ability to act as phytoestrogens.</p>

<p>3-Hydroxy-5,7-dimethoxyflavone is a naturally occurring flavonoid, which is primarily derived from various plant sources. This compound belongs to a class of polyphenolic substances known as flavonoids, which are commonly found in fruits, vegetables, and certain herbs. Flavonoids such as 3-Hydroxy-5,7-dimethoxyflavone are known for their diverse biological activities due to their unique structural configurations and ability to interact with various biological targets.</p>

<p>Icariside II is a natural product derived from Epimedium brevicornu Maxim (E. brevicornu) that exhibits various beneficial properties as a small molecule drug candidate. It has been shown to induce apoptosis in K562 cells, making it a potential treatment for leukemia. Icariside also regulates MAPK signaling, which plays a crucial role in cell growth and differentiation. Moreover, it has been found to promote osteogenesis, making it a promising candidate for bone health. With its unique properties and potential therapeutic applications, Icariside II is an interesting candidate for small molecule studies and drug development research.This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&amp;D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>

<p>2'-Methoxyflavonol is a methoxyflavonoid, which is a type of polyphenolic compound. It is derived from natural sources, primarily plants where flavonoids are commonly found. These compounds are known for their wide range of biological activities.</p>

<p>Phaseollinisoflavan is a naturally occurring isoflavone compound, which is derived from the legume plant, Phaseolus vulgaris, commonly known as the common bean. Its mode of action primarily involves the inhibition of enzymatic activity, particularly affecting pathways related to oxidative stress and various metabolic processes. This isoflavone exerts its effects by modulating signal transduction pathways, which are critical in cellular response mechanisms.</p>

<p>3',4',7-Trihydroxyflavone is a naturally occurring flavonoid compound, which is derived from a variety of plant sources. It is a type of secondary metabolite commonly found in fruits, vegetables, and certain herbs. This compound exerts its effects primarily through its antioxidant properties, which involve scavenging free radicals and modulating oxidative stress pathways in biological systems.</p>

<p>3',4',5',5,7-Pentamethoxyflavone is a synthetic flavonoid compound, which is derived from the structural modification of naturally occurring flavonoids found in various plants. The compound is specifically produced for research and development purposes, exploring its biological and pharmacological potential. The mode of action involves interaction with various cellular pathways, including modulation of enzyme activity, influence on cell signaling pathways, and potential antioxidant properties due to its polyphenolic structure.</p>

<p>Quercetin-7,4'-diglucoside is a flavonoid glycoside, which is a bioactive compound derived from various plants, particularly in fruits, vegetables, and certain leaves. It functions through its ability to modulate cellular pathways related to oxidative stress and inflammation, acting as a potent antioxidant and anti-inflammatory agent. These modes of action are primarily attributed to its capacity to scavenge free radicals and attenuate the expression of pro-inflammatory cytokines by interfering with signaling pathways, such as NF-κB and MAPK.</p>

<p>Inhibitor of HSP70 and HSP27 expression</p>

<p>Dihydroprunetin is a synthetic analog of natural flavonoid compounds, which is derived from chemical modifications of prunetin, originally sourced from various plant species. It functions primarily as an antioxidant by inhibiting oxidative stress pathways and scavenging free radicals. This activity is attributed to modifications that enhance its stability and bioavailability compared to its natural counterparts.</p>

<p>Dehydroequol is a dietary supplement ingredient, which is a metabolite of the soy isoflavone daidzein. It is produced through the biotransformation by certain gut bacteria that convert daidzein into equol compounds, specifically the dehydrogenated form. This compound is noted for its estrogenic activity, acting primarily as a selective estrogen receptor modulator (SERM). Dehydroequol binds to estrogen receptors with a preference for the beta subtype, exerting moderate estrogenic effects.</p>

<p>7-Benzyloxy-2',3',4'-trimethoxyisoflavone is a synthetic isoflavone, which is a type of flavonoid compound often derived from plant secondary metabolites. Its source lies in laboratory synthesis, using specific chemical reactions to obtain the desired isoflavone structure with a benzyloxy group and methoxy groups at specified positions on the molecule.</p>

<p>Natually produced by plants such as liquorice, liquiritin is formed by the linkage between liquiritigenin and a beta-D-glucopyranosyl residue at position 4. Liquiritin clinical relevance has been as an antiviral and anti-inflammatory agent. In 2020, an artificial intelligent approach has indicated that liquiritin might inhibit SARS-CoV-2 by acting similarly to type I interferon.</p>

<p>3',4',5'-Trimethoxyflavanone is a specialized flavonoid compound, which is synthesized from natural sources, such as plants belonging to the flavonoid family. This compound is characterized by its distinctive methoxy group modifications on the flavanone backbone, enhancing its bioactive potential. Its mode of action involves modulation of various biochemical pathways, including antioxidant systems and inflammatory mediators. By stabilizing free radicals and inhibiting pro-inflammatory enzymes, 3',4',5'-Trimethoxyflavanone plays a crucial role in cellular protection and homeostasis.</p>

<p>Eupafolin is a naturally occurring flavonoid compound, specifically a flavone, which is derived from certain medicinal plants, primarily in the genus *Artemisia*. It is a secondary metabolite found in various parts of these plants, including the leaves and stems. As a bioactive substance, eupafolin exerts its effects through several biochemical pathways, most notably by scavenging free radicals and modulating inflammatory responses. Its mode of action involves the inhibition of key enzymes and molecules in the inflammatory cascade, as well as the upregulation of antioxidant defenses.</p>

<p>Hesperetin is a flavonoid compound, which is naturally derived from citrus fruits such as oranges and lemons. As a notable bioactive molecule, its mode of action primarily involves the modulation of oxidative stress and inflammatory pathways. Hesperetin exerts its effects by scavenging free radicals and inhibiting the activation of inflammatory cytokines, making it a compound of significant interest in the biochemical and pharmacological sectors.</p>

<p>3,7,3'-Trihydroxyflavone is a flavonoid derivative, which is a type of polyphenolic compound commonly found in various plants and is derived from natural sources like fruits, vegetables, and herbal plants. It is characterized by its polyphenolic structure, which contributes to its ability to scavenge free radicals and reduce oxidative stress.</p>

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<p>2'-Hydroxy-β-naphthoflavone is a synthetic flavonoid, which is derived from structural modifications of natural flavonoids. It functions as a potent aryl hydrocarbon receptor (AhR) agonist and enzyme inducer. The structure is based on a naphthoflavone framework, allowing it to efficiently interact with cellular proteins related to xenobiotic metabolism.</p>

<p>3-Methoxyflavone is a synthetic flavonoid, which is a type of product known for its biological activities and potential therapeutic applications. It is derived from flavones, naturally occurring compounds found in various plants, known for their role in plant pigmentation and UV protection. The compound's mode of action is primarily through interaction with various biological targets, including modulation of enzyme activity and regulation of signal transduction pathways.</p>

<p>Apigenin-7-glucoside is a naturally occurring flavonoid glycoside, which is derived primarily from various plant sources, including parsley, celery, chamomile, and some fruits. This compound is formed when apigenin, a flavonoid, is conjugated with a glucose molecule. The interaction with glucose enhances its solubility and bioavailability in biological systems.</p>

<p>Hesperidin methylchalcone is a specialized flavonoid product, which is derived from citrus fruits, predominantly oranges. It is chemically modified from its natural form to enhance its solubility and bioavailability, making it more effective in biological systems. The mode of action of hesperidin methylchalcone involves the modulation of oxidative stress and inflammation within the body, primarily by acting as an antioxidant and anti-inflammatory agent. It achieves these effects by scavenging free radicals and inhibiting pro-inflammatory enzymes, which contributes to cellular protection and stabilization of connective tissues.</p>

<p>3-Hydroxy-7,2',4'-trimethoxyflavone is a specialized flavone compound, which is a type of polyphenolic molecule commonly found in a variety of plants. This product is naturally derived, often isolated from diverse botanical sources like various species of herbs and flowering plants known for their medicinal properties. The compound exhibits various biological activities through its interactions with cellular pathways, predominantly by modulating enzymatic functions and signaling pathways that influence oxidative stress and inflammation.</p>

<p>Alnusin is a phytochemical compound, which is a naturally occurring flavonoid sourced from the bark and leaves of the alder tree (genus Alnus). This compound is structurally categorized as an O-methylated flavonoid, specifically demonstrating unique biological activities.</p>

<p>Biflavonyl pigment; anti-inflammatory; analgesic</p>

<p>Tricetin is a naturally occurring flavonoid compound, which is primarily sourced from various plant species. Its molecular structure comprises multiple hydroxyl groups, contributing to its biological activity. Tricetin functions by modulating several biochemical pathways; it exhibits antioxidant properties through scavenging of reactive oxygen species and chelation of metal ions. Additionally, Tricetin possesses anti-inflammatory effects, as it can inhibit the synthesis of pro-inflammatory cytokines and downregulate the expression of enzymes involved in inflammation, such as cyclooxygenase and lipoxygenase.</p>

<p>3',4'-Dimethoxy-beta-naphthoflavone is a synthetic chemical compound, which is a selective aryl hydrocarbon receptor (AhR) agonist, derived from flavonoid structures. With its capacity to modulate xenobiotic metabolism, this compound acts as an inducer of cytochrome P450 enzymes, specifically CYP1A1 and CYP1A2, through the activation of the AhR pathway. Upon binding to AhR, 3',4'-Dimethoxy-beta-naphthoflavone translocates to the nucleus, where it influences gene expression involved in xenobiotic metabolism.</p>

<p>Scutellarein-6,4'-dimethyl ether is a flavonoid derivative, which is a type of polyphenolic compound widely found in the plant kingdom. It is primarily sourced from various species within the genus Scutellaria, known for their rich flavonoid content. Scutellarein-6,4'-dimethyl ether demonstrates an affinity for interacting with key biological pathways, including exerting possible antioxidant activities by scavenging free radicals and modulating redox states, as well as potential anti-inflammatory effects through the regulation of inflammatory mediators.</p>

<p>Kaempferol-3-O-rhamnoside is a naturally occurring flavonoid glycoside, which is derived from various plants, particularly those in the families Rosaceae and Brassicaceae. This compound is a significant bioactive component found in herbs, fruits, and vegetables. Its mode of action primarily involves the scavenging of free radicals, inhibition of oxidative stress, and modulation of various signaling pathways related to inflammation and apoptosis.</p>

<p>Mucronulatol is a naturally occurring compound, which is derived from certain plant species known for their rich array of bioactive compounds. As a product of natural origin, mucronulatol is classified as a polyphenolic compound. Its biosynthesis in plants is a part of the complex secondary metabolism, playing roles in defense mechanisms against environmental stressors and pathogens. The mode of action of mucronulatol involves modulation of various biochemical pathways, which may include antioxidant activity, enzyme inhibition, or signaling pathway regulation. This capacity makes mucronulatol a subject of interest in pharmacological and therapeutic research.</p>

<p>Kaempferol-3,4'-diglucoside is a glycosylated flavonoid, which is a type of chemical compound found abundantly in various plants. This product is derived from natural sources, particularly from several edible and medicinal plants known for their health benefits. Kaempferol-3,4'-diglucoside functions through mechanisms related to its antioxidant properties, scavenging free radicals and reducing oxidative stress within biological systems.</p>

<p>Naringenin trimethyl ether is a flavonoid compound, which is typically derived from citrus fruits and other plant sources. This compound is part of the larger class of polyphenolic compounds known as flavonoids, which are prominent for their presence in various plant species, contributing to a variety of physiological activities.</p>

<p>4',7-Dihydroxy-2-methoxyisoflavone is a naturally occurring isoflavone, which is a type of phytochemical compound typically found in the Leguminosae family of plants. These plants are well-known for their rich source of bioactive compounds. This specific isoflavone is primarily isolated from plants like red clover or soybeans, which are renowned for their beneficial bioactive constituents.</p>

<p>2'-Hydroxyflavonol is a flavonoid derivative, which is a polyphenolic compound commonly found in plants. This compound is derived from natural sources, particularly various fruits, vegetables, and roots. Its mode of action is primarily through its role as an antioxidant, where it scavenges free radicals, thereby reducing oxidative stress. Furthermore, it can modulate multiple signaling pathways, contributing to its various bioactivities.</p>