Cannabinoids
Cannabinoids are a class of diverse chemical compounds derived from fatty acids or polyketides that act on cannabinoid receptors in cells, altering neurotransmitter release in the brain. Found primarily in cannabis plants, cannabinoids like THC and CBD are widely studied for their therapeutic effects, including pain relief, anti-inflammatory properties, and potential use in neurodegenerative diseases. At CymitQuimica, you will find a wide variety of cannabinoids for research in pharmacology, neurobiology, and medical chemistry.
Found 323 products of "Cannabinoids"
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δ9-Tetrahydrocannabivarinic acid (THCVA) 1000 µg/mL in Methanol
CAS:Controlled ProductFormula:C20H26O4Color and Shape:Single SolutionMolecular weight:330.42(-)-δ 8-Tetrahydrocannabinol (δ8-THC) 1000 µg/mL in Methanol
CAS:Controlled ProductFormula:C21H30O2Color and Shape:ColourlessMolecular weight:314.46δ 9-Tetrahydrocannabinolic Acid A (THCA-A) 1000 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C22H30O4Color and Shape:ColourlessMolecular weight:358.47Otenabant hydrochloride
CAS:Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).Formula:C25H26Cl3N7OPurity:99.79% - ≥95%Color and Shape:SolidMolecular weight:546.88A-836339
CAS:A-836339: Potent cannabinoid, CB2-focused (Ki=0.64nM), lesser CB1 affinity (Ki=270nM); analgesic, anti-inflammatory in mice.Formula:C16H26N2O2SPurity:99.94%Color and Shape:SolidMolecular weight:310.45Ref: TM-T7375
2mg34.00€5mg67.00€10mg109.00€25mg177.00€50mg260.00€100mg369.00€200mg500.00€1mL*10mM (DMSO)63.00€AM1241
CAS:AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.Formula:C22H22IN3O3Purity:98.937% - 99.1%Color and Shape:SolidMolecular weight:503.33Ref: TM-T6755
2mg35.00€5mg49.00€10mg84.00€25mg168.00€50mg275.00€100mg495.00€500mg1,071.00€1mL*10mM (DMSO)87.00€Org 27569
CAS:Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity andFormula:C24H28ClN3OPurity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:409.95ARN272
CAS:ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).Formula:C27H20N4O2Purity:98.23%Color and Shape:SolidMolecular weight:432.47RTICBM-189
CAS:RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay.Formula:C15H14Cl2N2OPurity:99.96%Color and Shape:SolidMolecular weight:309.19Ref: TM-T9466
2mg34.00€5mg52.00€10mg84.00€25mg161.00€50mg250.00€100mg369.00€200mg522.00€1mL*10mM (DMSO)67.00€Otenabant
CAS:Otenabant (CP-945598) has been investigated for the treatment of Obesity.Formula:C25H25Cl2N7OPurity:99.43%Color and Shape:SolidMolecular weight:510.42β-Caryophyllene
CAS:β-Caryophyllene ((-)-(E)-Caryophyllene) acts as an CB2 receptor agonist.Formula:C15H24Purity:95.43% - 99.11%Color and Shape:Turpentine (Ntp 1992)Molecular weight:204.35N-Oleoyl glycine
CAS:N-Oleoyl glycine, a lipoamino acid, was able to promote 3T3-L1 adipogenesis through the activation of CB1 receptor and the enhancement of insulin-mediated AktFormula:C20H37NO3Purity:97.43%Color and Shape:SolidMolecular weight:339.51Bay 59-3074
CAS:Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM).
Formula:C18H13F6NO4SPurity:97.68% - 99.69%Color and Shape:SolidMolecular weight:453.36CID 16020046
CAS:CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.Formula:C25H19N3O4Purity:99.03%Color and Shape:SolidMolecular weight:425.44PSB-SB-487
CAS:PSB-SB-487 is antagonist of GPR55.Formula:C26H32O4Purity:98.53%Color and Shape:SolidMolecular weight:408.53Ref: TM-T8975
1mg35.00€5mg80.00€10mg119.00€25mg231.00€50mg344.00€100mg480.00€200mg660.00€1mL*10mM (DMSO)87.00€Voacamine
CAS:Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.
Formula:C43H52N4O5Purity:98.54% - 99.82%Color and Shape:SolidMolecular weight:704.9Hemopressin (rat) acetate(568588-77-2 free base)
Hemopressin is a nonapeptide, CB2 agonist, derived from rat hemoglobin, with antinociceptive properties.Formula:C5H81N13O14Purity:99.37%Color and Shape:SolidMolecular weight:1148.31JD-5037
CAS:JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.Formula:C27H27Cl2N5O3SPurity:99.54% - 99.84%Color and Shape:SolidMolecular weight:572.51Ref: TM-T4453
1mg42.00€2mg55.00€5mg90.00€10mg133.00€25mg234.00€50mg350.00€100mg522.00€1mL*10mM (DMSO)101.00€RVD-Hpα acetate(1193362-76-3 free base)
RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.Formula:C67H109N19O19Purity:99.87%Color and Shape:SolidMolecular weight:1484.71(±)-Ibipinabant
CAS:(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.Formula:C23H20Cl2N4O2SPurity:99.28% - 99.83%Color and Shape:SolidMolecular weight:487.4ML-193
CAS:ML-193: GPR55 antagonist, IC50 221nM, 27x selective over GPR35/CB1/CB2, may aid Parkinson's symptoms.Formula:C28H25N5O4SPurity:97.74%Color and Shape:SolidMolecular weight:527.59yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Formula:C15H14O4Purity:98.82% - 99.55%Color and Shape:Pale Yellow PowderMolecular weight:258.27Ref: TM-T3S0738
1mg70.00€5mg135.00€10mg207.00€25mg349.00€50mg515.00€100mg735.00€1mL*10mM (DMSO)177.00€AM-2232
CAS:AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.Formula:C24H20N2OPurity:99.37%Color and Shape:SolidMolecular weight:352.43Linoleoyl Ethanolamide
CAS:Linoleoyl Ethanolamide is an endocannabinoid agent.Formula:C20H37NO2Purity:99.97%Color and Shape:SolidMolecular weight:323.51Ref: TM-T8425
1mg35.00€5mg67.00€10mg90.00€25mg164.00€50mg239.00€100mg348.00€200mg522.00€1mL*10mM (DMSO)85.00€CB1 antagonist 4
CAS:TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.Formula:C30H25Cl2F3N4OSPurity:98.97%Color and Shape:SolidMolecular weight:617.51Ref: TM-T8511
2mg46.00€5mg92.00€10mg152.00€25mg259.00€50mg405.00€100mg597.00€200mg848.00€1mL*10mM (DMSO)155.00€GW 405833
CAS:GW 405833 (L-768242) is an agonist of cannabinoid-2 (CB(2)) receptor-selectiveFormula:C23H24Cl2N2O3Purity:99.82% - 99.93%Color and Shape:SolidMolecular weight:447.35Hemopressin (human, mouse) acetate
Hemopressin: Nonapeptide, α1-hemoglobin derivative, CB1 inverse agonist, isolated from rats, oral, reduces inflammatory pain.Formula:C52H83N13O14Purity:99.86%Color and Shape:SolidMolecular weight:1114.29LY2828360
CAS:LY2828360: CB2 agonist, Ki=40.3 nM; biases CB2 over CB1 with EC50s of 20.1 nM and >100 μM.Formula:C22H27ClN6OPurity:98.45% - 99.51%Color and Shape:SolidMolecular weight:426.94Tetrahydromagnolol
CAS:Tetrahydromagnolol can activate cannabinoid (CB) receptors.Formula:C18H22O2Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:270.37Ref: TM-TN2268
2mgTo inquire5mg52.00€10mg81.00€25mgTo inquire50mg170.00€100mg243.00€1mL*10mM (DMSO)63.00€Olivetol
CAS:Olivetol, found in lichens, is an organic antioxidant and THC synthesis precursor.Formula:C11H16O2Purity:99.98%Color and Shape:(Melting Point 102-106°F) (Ntp 1992)Molecular weight:180.24AM251
CAS:AM251: potent CB1 blocker (IC50: 8 nM), 306x CB2 selective; GPR55 activator (EC50: 39 nM).Formula:C22H21Cl2IN4OPurity:97.43% - 98.79%Color and Shape:A Crystalline SolidMolecular weight:555.24ML-191
CAS:ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.Formula:C24H25N3O3Purity:99.58%Color and Shape:SolidMolecular weight:403.47ML-184
CAS:ML-184 (CID2440433) is a potent synthetic agonist of GPR55 with EC50 of 0.26 μM.Formula:C25H34N4O3SPurity:99.45%Color and Shape:SolidMolecular weight:470.63AM281
CAS:AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.Formula:C21H19Cl2IN4O2Purity:98.6% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:557.21Ref: TM-T2264
1mg80.00€5mg169.00€10mg259.00€25mg523.00€50mg750.00€100mg1,035.00€500mg2,062.00€1mL*10mM (DMSO)233.00€GW842166X
CAS:GW842166X: Potent CB2 agonist, EC50=63 nM, inactive at CB1, in Phase 2 trials.Formula:C18H17Cl2F3N4O2Purity:99.47%Color and Shape:SolidMolecular weight:449.25WIN 55,212-2 Mesylate
CAS:WIN 55,212-2 Mesylate ((R)-(+)-WIN 55212) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. Cannabinoid analogue WIN 55,212-2 Mesylate exhibited a novel anticancer effect against human tumors.Formula:C28H30N2O6SPurity:98% - 99.71%Color and Shape:White To Off-White SolidMolecular weight:522.61CB1-IN-1
CAS:CB1-IN-1 (DBPR211) is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.Formula:C33H31Cl2F3N6O3S2Purity:99.08% - 99.76%Color and Shape:SolidMolecular weight:751.67Ref: TM-T5996
1mg82.00€2mg110.00€5mg180.00€10mg258.00€25mg423.00€50mg588.00€100mg793.00€500mg1,594.00€1mL*10mM (DMSO)215.00€BML-190
CAS:BML-190 (Indomethacin morpholinylamide) 是一种 CB2 受体的配体，其对 CB2 受体 (Ki:435 nM) 和 CB1受体 (Ki> 2 μM)。Formula:C23H23ClN2O4Purity:97.70%Color and Shape:SolidMolecular weight:426.89Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFormula:C21H32O2Purity:99.59% - 99.92%Color and Shape:SolidMolecular weight:316.48Ref: TM-TN1465
1mg138.00€2mg203.00€5mg298.00€10mg449.00€25mg765.00€50mg1,054.00€100mg1,423.00€1mL*10mM (DMSO)306.00€Cannabigerol
CAS:PolyphenolFormula:C21H32O2Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:316.48Cannabicitran
CAS:Aromatic etherFormula:C21H30O2Purity:≥ 95.0 % (HPLC)Color and Shape:LiquidMolecular weight:314.46Cannabigerolic acid
CAS:Carboxylic acid with phenol functionFormula:C22H32O4Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:360.49Cannabidiol
CAS:PolyphenolFormula:C21H30O2Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:314.464-monobromocannabidiol
CAS:Halogen derivative of polyphenolFormula:C21H29BrO2Purity:≥ 90.0 % (HPLC)Color and Shape:Viscous liquidMolecular weight:393.36Cannabichromenic acid
CAS:Carboxylic acid with phenol functionFormula:C22H30O4Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:358.47Cannabidiolic acid
CAS:Carboxylic acid with phenol functionFormula:C22H30O4Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:358.47Cannabidiol hydroxyquinone
CAS:QuinoneFormula:C21H28O3Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:328.45Cannabichromevarinic acid
CAS:Carboxylic acid with phenol functionFormula:C20H26O4Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:330.42Cannabinol
CAS:Oxygen-heterocyclic compoundFormula:C21H26O2Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:310.43Cannabidivarin
CAS:PolyphenolFormula:C19H26O2Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:286.41S-Methoprene
CAS:S-Methoprene (ZR2458), a juvenile hormone analog, acts as an insecticide influencing redox activity and male sex differentiation.
Formula:C19H34O3Purity:97.05% - 98.55%Color and Shape:SolidMolecular weight:310.47(1S,4R)-1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol
CAS:Controlled ProductApplications 1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol is an acetal reagent used in the synthesis of desoxy cannabidiols and THC (T293202) related psychoactive compounds. It is formed from (+)-Limonene using a photosynthesized O2 transfer.
References Wilkinson, S. et al.: Tetrahedron Lett., 54, 52 (2013);Formula:C10H16OColor and Shape:NeatMolecular weight:152.23(-)-Isoperitenone
CAS:Controlled ProductApplications (-)-Isoperitenone, is a derivative of (-)-Cannabidiol (C175300), a major, non psychotropic constituent of cannabis.
References Hanus, L. et al.: Organic & Biomolecular Chemistry, Vol.3, Issue 6 (2005);Formula:C10H14OColor and Shape:NeatMolecular weight:150.22CB1/2 agonist 3
CAS:CB1/2 agonist 3 is a competitive and potent CB1/CB2 agonist with high affinity for hCB1 and hCB2 and can be used to study neurological disorders.Formula:C25H41NO2Purity:98.78%Color and Shape:SolidMolecular weight:387.6Isocannabichromen
CAS:Controlled ProductFormula:C21H30O2Color and Shape:Light Yellow To Dark YellowMolecular weight:314.47C2
CAS:Positive allosteric modulator (PAM) of cannabinoid receptors CB2. The C2 modulator is the first synthetic PAM of CB2 receptors with antinociceptive properties, which were observed in a mouse model of neuropathic pain.Formula:C21H24BrFN2O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:435.33 g/molACEA, 5mg/ml solution in ethanol
CAS:Cannabinoid type 1 (CB1) receptor agonist. Anti-depressant activity demonstrated in vivo alone, as well as enhancing the effect of fluoxetine. In the brain, ACEA activates CB1 receptors expressed in the mitochondria of neuronal cells to elicit neuroprotective effects. This is mediated by inducing glycogen synthase kinase-3β (GSK-3β) phosphorylation and inhibiting the opening of mitochondrial permeability transition pore (MPTP). Sold by weight of solidFormula:C22H36ClNOPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:365.98 g/molAPD 371
CAS:A selective cannabinoid receptor type 2 (CB2) agonist. Commonly, CB2 agonists induce receptor internalization, which results in desensitization and tachyphylaxis. However, APD 371 mediates efficient recycling of internalized receptors back to the plasma membrane and thus sustains analgesic effects, upon subchronic treatment, in an osteoarthritis pain model in vivo.
Formula:C18H23N5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:357.41 g/molGW 833972A
CAS:A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).Formula:C18H13ClF3N5OPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:407.78 g/molrel-(1R,2S)-8-Bromo-1-(3-bromo-4-hydroxy-5-methoxyphenyl)-1,2-dihydro-7-hydroxy-N2,N3-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-2,3-na phthalenedicarboxamide
CAS:rel-(1R,2S)-8-Bromo-1-(3-bromo-4-hydroxy-5-methoxyphenyl)-1,2-dihydro-7-hydroxy-N2,N3-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-2,3-naphthalenedicarboxamide is a synthetic chemical compound, which is derived through targeted organic synthesis and structural optimization efforts. Its source lies in advanced laboratory methodologies designed to enhance specific pharmacological properties. The mode of action is expected to involve selective interaction with particular molecular targets, potentially modulating distinct pathways related to cellular function or signaling processes.Formula:C36H34Br2N2O8Purity:Min. 95%Color and Shape:PowderMolecular weight:782.47 g/molGW 833972A
CAS:A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).Formula:C18H13ClF3N5O•HClPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:444.24 g/mol2-(2,5-Dimethoxy-4-methylphenyl)-4,5-dihydro-4,4-dimethyloxazole
CAS:Controlled ProductFormula:C14H19NO3Color and Shape:NeatMolecular weight:249.315-(4-Hydroxypentyl)-1,3-benzenediol
CAS:Controlled ProductApplications 5-(4-Hydroxypentyl)-1,3-benzenediol is an intermediate used in the synthesis of 4''-Hydroxycannabidiol (H824830), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 4''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.
References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)Formula:C11H16O3Color and Shape:NeatMolecular weight:196.24(Z)-1-Chloro-2-nonene
CAS:Controlled ProductApplications (Z)-1-Chloro-2-nonene is an intermediate in the synthesis of Falcarinol (F101100), a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin.
References Czepa, A., et al.: J. Agric. Food Chem., 52, 4508 (2004), Radulovic, N., et al.: Chem. Nat. Compds., 44, 390 (2008),Formula:C9H17ClColor and Shape:NeatMolecular weight:160.68Methyl 1-(Cyclohexylmethyl)-1H-indazole-3-carboxylate
CAS:Controlled ProductApplications Methyl 1-(Cyclohexylmethyl)-1H-indazole-3-carboxylate is an intermediate in the synthesis of MDMB-CHMINACA (M203515), a synthetic cannabinoid with potential neurochemical effects at the CB1 receptor.
References Banister, S. ET AL.: ACS Chem. Neurosci., 7, 1241 (2016);Formula:C16H20N2O2Color and Shape:NeatMolecular weight:272.34Cannabigerovarinic acid
CAS:Carboxylic acid with phenol functionFormula:C20H28O4Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:332.43PSB-KK1445
CAS:PSB-KK1445 is a potent and selective agonist of GPR18, exhibiting EC50 values of 45.4 nM for humans and 124 nM for mice. The selectivity of PSB-KK1445 for GPR18 over the CB receptor subtypes GPR55 and GPR183 exceeds 200-fold.Formula:C24H23FN6O2Molecular weight:446.48Dehydroabiethylamine
CAS:Dehydroabiethylamine (NSC-2955) boosts liver CYP2B, blocks PDKs & cholesterol transport, and has anti-tumor effects.Formula:C20H31NPurity:98.79%Color and Shape:Pale Yellow Viscous Liquid /Technical Grade/ Viscous Colorless To Amber LiquidMolecular weight:285.47N-(1H-Indazol-3-ylcarbonyl)-3-methyl-D-valine methyl ester
Formula:C15H19N3O3Color and Shape:NeatMolecular weight:289.341-(3,5-Bis(benzyloxy)phenyl)pent-1-en-3-one
CAS:Controlled ProductStability Light Sensitive
Applications (Z)-1-(3,5-Bis(benzyloxy)phenyl)pent-1-en-3-one is a reagent in the synthesis of 3''-Hydroxycannabidiol (H824825) which is a major constituents in marijuana. 3''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.
References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)Formula:C25H24O3Color and Shape:NeatMolecular weight:372.46(S)-2-Benzylaziridine
CAS:Controlled ProductApplications (S)-2-Benzylaziridine is a reagent for the synthesis of renin inhibitors, taurine and cannabinoid type 2 (CB2) receptor agonists.
References Kaltenbronn, J. S., et al.: J. Med. Chem 33, 838 (1990); Hu, L., et al.: J. Org. Chem. 72, 4543 (2007); Matsushima, Y., et al.: Jpn. Kokai Tokkyo Koho JP 2012072067 A 20120412 (2012)Formula:C9H11NColor and Shape:NeatMolecular weight:133.19(5Z,8Z,11Z,14Z)-2-[[Tris(1-methylethyl)silyl]oxy]-5,8,11,14-eicosatetraenoic Acid 1-[[[Tris(1-methylethyl)silyl]oxy]methyl]ethyl Ester
CAS:Controlled ProductApplications (5Z,8Z,11Z,14Z)-2-[[Tris(1-methylethyl)silyl]oxy]-5,8,11,14-eicosatetraenoic Acid 1-[[[Tris(1-methylethyl)silyl]oxy]methyl]ethyl Ester is an intermediate in the synthesis of 2-Arachidonoylglycerol (A765050), an major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors.
References Baur, R., et al.: J. Neurochem., 126, 29 (2013); Fanelli, F., et al.: J. Lipid. Res., 53, 481 (2012);Formula:C41H78O4Si2Color and Shape:NeatMolecular weight:691.231-(3,5-Bis(benzyloxy)phenyl)pentan-1-ol
CAS:Controlled ProductFormula:C25H28O3Color and Shape:NeatMolecular weight:376.493-[4-(1,1-Dimethylheptyl)-2-(phenylmethoxy)phenyl]cyclohexanone
CAS:Controlled ProductApplications Intermediate in the synthesis of a cannabinoid receptor ligand.
Formula:C28H38O2Color and Shape:NeatMolecular weight:406.6Cannabigerorcinic Acid
CAS:Controlled ProductStability Light Sensitive
Applications Cannabigerorcinic Acid is a compound that takes part in the biosynthesis of daurichromenic acid synthase which is active in anti-HIV biosynthesis.
References Iijima, M. et al.: Plant Phys., 174, 2213 (2017);Formula:C18H24O4Color and Shape:NeatMolecular weight:304.38Ethyl 2-Oxopentanoate
CAS:Controlled ProductApplications Ethyl 2-oxopentanoate is used as a reagent to synthesize selective CB1 cannabinoid receptor antagonists. Ethyl 2-oxopentanoate is also used to synthesize derivatives of iminodiacid, an inhibitor of angiotensin converting enzyme.
References Lange, J., et al.: J. Med. Chem., 48, 1823 (2005); Vincent, M., et al.: Tetrahedron Lett., 23, 1677 (2982)Formula:C7H12O3Color and Shape:NeatMolecular weight:144.17N-Arachidonyldopamine
CAS:N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1Formula:C28H41NO3Purity:97.65%Color and Shape:SolidMolecular weight:439.632-Arachidonoylglycerol
CAS:In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligandFormula:C23H38O4Purity:95%Color and Shape:LiquidMolecular weight:378.55CID1792197
CAS:CID1792197 is a selective agonist of GPR55.Formula:C24H23N3O4S2Purity:98%Color and Shape:SolidMolecular weight:481.59GPR55 agonist 3
CAS:Compound 26, a GPR55 agonist, exhibits potent activity with EC50 values of 0.239 nM for hGPR55 and 1.76 nM for rGPR55.Formula:C19H16F4N4Color and Shape:SolidMolecular weight:376.35PM226
CAS:CB2 agonist with Ki of 12.8 nM; EC50 of 38.67 nM. Negligible CB1 affinity, no GPR55 activity. Anti-inflammatory, neuroprotective, crosses BBB.Formula:C22H31NO3Color and Shape:SolidMolecular weight:357.49TC-C 14G
CAS:CB1 receptor inverse agonistFormula:C24H17Cl2F2NO4Purity:98%Color and Shape:SolidMolecular weight:492.3ZCZ011
CAS:ZCZ011 enhances CB1 receptor effects, crosses blood-brain barrier, and potentiates cannabimimetic behaviors in mice.Formula:C21H18N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.44Palmitoyl serinol
CAS:Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor and antileukemic activities.Formula:C19H39NO3Color and Shape:SolidMolecular weight:329.52UCM 707
CAS:endocannabinoid transport inhibitorFormula:C25H37NO2Purity:98%Color and Shape:SolidMolecular weight:383.57CB1-IN-2
CAS:CB1-IN-2 (4g) inhibits CB1 receptor with 0.644 μM IC50; crosses blood-brain barrier, may cause CNS side effects like Rimonabant.Formula:C17H19Cl2N5OColor and Shape:SolidMolecular weight:380.27LEI-101
CAS:LEI-101: potent CB2 agonist, pEC50=8, bioavailable, >100x selective over CB1, potential for inflammatory diseases.Formula:C23H25FN4O4SPurity:98%Color and Shape:SolidMolecular weight:472.53VSN-16
CAS:VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis.Formula:C18H26N2O3Color and Shape:SolidMolecular weight:318.41UCM710
CAS:UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).Formula:C19H34O3Purity:98%Color and Shape:SolidMolecular weight:310.47CB1R Allosteric modulator 4
CAS:Modulates CB1R positively; inhibits cAMP production; strong β-arrestin-2 recruitment.Formula:C20H17N3O2SColor and Shape:SolidMolecular weight:363.43CB1/2 agonist 4
CAS:CB1/2 agonist 4 is a potent CB1 full agonist (EC50: 15.09 nM) and CB2 partial agonist (EC50: 1.16 nM), with anti-pain and TRPV1 activation properties.Formula:C27H45NO3Color and Shape:SolidMolecular weight:431.65(R)-SLV 319
CAS:(R)-SLV 319: potent CB1 antagonist, K i of 894 nM, dextrorotatory isomer.Formula:C23H20Cl2N4O2SColor and Shape:SolidMolecular weight:487.4LH 21
CAS:LH-21, a strong CB1 receptor antagonist, curbs eating and lessens weight gain in obese rats.Formula:C20H20Cl3N3Color and Shape:SolidMolecular weight:408.75
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