Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
3-N-Boc-5'-O-DMT-3'-fluorothymidine
CAS:3-N-Boc-5'-O-DMT-3'-fluorothymidine is a monophosphate nucleoside with antiviral and anticancer activity. It is a novel synthetic analogue of fluoro thymidine (FT) that has been shown to be an activator of DNA polymerase α, RNA polymerase β and γ, and protein kinase C. This compound is also an inhibitor of the reverse transcriptase enzyme HIV-1. 3-N-Boc-5'-O-DMT-3'-fluorothymidine has been shown to inhibit cancer cell growth in vitro and in vivo. The synthesis of this compound can be achieved by phosphoramidite chemistry using a commercially available automated synthesizer.Purity:Min. 95%2,6-Dichloro-9-(β-D-ribofuranosyl)purine
CAS:2,6-Dichloro-9-(β-D-ribofuranosyl)purine is a nucleoside analog composed of a modified purine base and a ribose sugar. It has possible applications as an intermediate in nucleoside chemistry, particularly for the synthesis of functionalized purine nucleosides used in biological and pharmaceutical research.Formula:C10H10Cl2N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:321.12 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.Purity:Min. 95%Guanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt
CAS:Guanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt (GMPP) is an analog of guanosine triphosphate that is enzymatically inactivated by the enzyme kinesin. GMPP inhibits the polymerization of microtubules by binding to the kinesin molecule and preventing it from binding to tubulin. GMPP has been shown to inhibit sephadex g-100 chromatography and act as a competitive inhibitor for protein synthesis in vitro. GMPP has also been shown to have a fat cell differentiation effect which may be due to its ability to inhibit microtubule polymerization.Formula:C11H18N5O13P3·xNaPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:521.21 g/mol2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite
2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is a novel nucleoside analog that has been synthesized to have the same chemistry as 2,3'-dideoxycytidine 5'-C phosphoramidite. It has antiviral and anticancer properties. This compound can be used in the synthesis of oligonucleotides for DNA sequencing and for gene therapy. 2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is not toxic to normal cells, but it inhibits replication of viruses such as HIV and herpes simplex virus.Formula:C25H32N5O5PPurity:Min. 95%Molecular weight:513.54 g/mol5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine
CAS:5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine is an antiviral drug that inhibits the synthesis of viral DNA. It is synthesized by reacting 5'-deoxyadenosine monophosphate with 2'-O-(2-methoxyethyl)iodoacetamide and methylating the resulting product with methyl iodide. 5'-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine has a novel structure and can be used as an activator of ribonucleosides in DNA synthesis. The drug also has anticancer properties, which may be due to its ability to inhibit cellular proliferation by inhibiting the enzyme DNA polymerase or by arresting cells at the G1 phase of the cell cycle.Purity:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS:N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine is a cytosine analog with high affinity for the T cell receptor. It can be used to generate antibodies against cytosine and as a screening tool for plasmon resonance.
Formula:C32H32FN3O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:589.61 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine
CAS:4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine is a novel nucleoside analog with antiviral and anticancer activities. It is a chemical compound with the molecular formula C8H14N6O5P and a molecular weight of 288.28 g/mol. 4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine has the CAS number 136045902, which can be found in PubChem Compound Database.Purity:Min. 95%1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine
1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine is a deoxyribonucleoside, modified nucleoside that is synthesized by using a novel phosphoramidite chemistry. 1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine is an activator of ribonucleotide reductase and can be used in anticancer and antiviral therapy.Purity:Min. 95%N6-Dimethyl-3’-b-C-methyladenosine
CAS:N6-Dimethyl-3’-b-C-methyladenosine is a novel nucleoside analog that has antiviral and anticancer properties. It is a phosphoramidite, which can be used as an activator for the synthesis of modified oligonucleotides. N6-Dimethyl-3’-b-C-methyladenosine has been shown to activate ribonucleosides and deoxyribonucleosides in vitro. This compound also has anticancer properties, which may be due to its ability to act as an activator in the synthesis of DNA.Purity:Min. 95%1'-13CCytidine
CAS:Please enquire for more information about 1'-13CCytidine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:CC8H13N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:244.21 g/mol2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate
2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate is an antiviral nucleoside with anticancer properties that is synthesized from 2'-deoxyuridine monophosphate and 5-methyluridine. This novel compound has shown antiviral activity against HIV, herpes simplex virus type 1, and herpes simplex virus type 2. It also inhibits the growth of human breast cancer cells in vitro.Purity:Min. 95%5'-O-p-Anisoyl-D3-thymidine
Controlled Product5'-O-p-Anisoyl-D3-thymidine is a nucleoside analogue that is used in antiviral and anticancer treatments. It is synthesized by the condensation of 3,4-dihydroxyacetophenone with 2,6-diaminopurine followed by phosphorylation of the 5' hydroxyl group. This product has been shown to be an activator of both DNA polymerase and RNA polymerase. In addition, it can inhibit the production of viral proteins such as HIV protease without affecting protein synthesis in mammalian cells. It also inhibits cancer cell growth by stopping DNA replication at the G2 phase. 5'-O-p-Anisoyl-D3-thymidine has been shown to be highly purified and can be used for research purposes. This product may have a CAS number but it will not be listed on this website due to company policy.Formula:C18H17N2O7D3Purity:Min. 95%Molecular weight:379.38 g/mol2'-O-(2-Methoxyethyl)-5-methyluridine
CAS:2'-O-(2-Methoxyethyl)-5-methyluridine is a uridine nucleoside that has been prepared by the reaction of amidite with 5-methyluridine. 2'-O-(2-Methoxyethyl)-5-methyluridine is an important intermediate in the synthesis of oligonucleotides, which are synthesized from phosphoramidites. The phenyl group on the amido group is a reactive group that reacts with other functional groups to form an oligonucleotide. 2'-O-(2-Methoxyethyl)-5-methyluridine has a high yield and can be used as a reagent for organic chemistry.Formula:C13H20N2O7Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:316.31 g/mol2'-Deoxy-5-(2-iodoethyl)uridine
CAS:2'-Deoxy-5-(2-iodoethyl)uridine is a nucleoside analog with antiviral and anticancer activity. It has been shown to be an activator of DNA replication, as well as inhibiting the synthesis of deoxyribonucleotides. This drug also has a novel structure that is modified from the natural nucleosides found in DNA and RNA. 2'-Deoxy-5-(2-iodoethyl)uridine can be synthesized using phosphoramidites, which are activated by iodine and sulfurizing agents. The purity of this compound is high and it is available at high quality.Purity:Min. 95%3'-O-DMT-thymidine 3'-succinyl CPG 500 Å
3'-O-DMT-thymidine 3'-succinyl CPG 500 Å is an activator for DNA synthesis and antiviral agent. It is a modified nucleoside that can be incorporated into DNA. This product is also used as a monophosphate in the synthesis of deoxyribonucleosides, which are used in the manufacture of DNA. 3'-O-DMT-thymidine 3'-succinyl CPG 500 Å has been shown to have antiviral properties against influenza and herpes simplex virus type 1 (HSV1). The anticancer activity of this product may be due to its ability to inhibit DNA replication and RNA transcription by binding to DNA polymerase and RNA polymerase, respectively.Purity:Min. 95%4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
CAS:4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a nucleoside monophosphate that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by inhibiting the activity of enzymes needed for nucleotide synthesis. 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine has shown anticancer properties in vitro against human colon cancer cells. This drug has been shown to inhibit the growth of tumor cells with high expression levels of cyclin D1 and low levels of p27 (a cell cycle regulatory protein).Purity:Min. 95%Thymidine
CAS:Thymidine is a nucleoside that is found in cells and is involved in the synthesis of DNA. Thymidine has been shown to inhibit the growth of tumor cells through apoptosis. In addition, thymidine can be used for the treatment of bowel disease by reducing inflammation and increasing the production of mucin. The mechanism by which thymidine exerts its effects on tumor cells is not well understood, but it may involve interactions with dna binding activity and enzyme activities.
Formula:C10H14N2O5Purity:Min. 99 Area-%Molecular weight:242.23 g/molRef: 3D-Q-201829
1kgTo inquire5kgTo inquire250gTo inquire500gTo inquire2500gTo inquire-Unit-kgkgTo inquireN2,N2-Dimethylguanosine
CAS:N2,N2-Dimethylguanosine is a purine nucleoside that is found in human serum. It belongs to the group of purines and has been shown to be involved in energy metabolism. N2,N2-Dimethylguanosine has been shown to be present at high levels in patients with autoimmune diseases such as rheumatoid arthritis. The x-ray crystal structures of wild-type strains of Escherichia coli and Streptococcus pneumoniae have been determined, which revealed that this compound interacts with the enzyme activity for primary sclerosing cholangitis. This nucleoside can also be detected by LC-MS/MS methods and multivariate logistic regression analysis.Formula:C12H17N5O5Purity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:311.3 g/mol3'-Amino-2',3'-dideoxycytidine
CAS:3'-Amino-2',3'-dideoxycytidine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics.Formula:C9H14N4O3Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:226.23 g/mol2',3'-Dideoxy-5-iodouridine
CAS:2',3'-Dideoxy-5-iodouridine is a synthetic nucleoside analog derived from uridine, one of the natural building blocks of RNA. This molecule has been chemically modified to disrupt the normal processes of DNA and RNA synthesis, making it a candidate for antiviral and anticancer research.Formula:C9H11IN2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:338.1 g/mol5'-O-p-Anisoyl-D3-thymidine 3'-CE phosphoramidite
Controlled Product5'-O-p-Anisoyl-D3-thymidine 3'-CE phosphoramidite is a monophosphate nucleoside analog, which is an important building block for the synthesis of oligonucleotides and DNA. The material is synthesized by coupling anisoyl chloride with D3-thymidine 3'-phosphate in the presence of a base. 5'-O-p-Anisoyl-D3-thymidine 3'-CE phosphoramidite has been shown to be effective against cancer cells, as well as viral infections. It also has antiviral properties and can be used for the treatment of hepatitis C.Formula:C27H34N4O8PD3Purity:Min. 95%Molecular weight:579.61 g/mol[2'-18O]Guanosine
[2'-18O]Guanosine is a novel antiviral that has shown antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It also has anticancer effects, as it inhibits the growth of lymphoma cells by inhibiting DNA synthesis. [2'-18O]Guanosine is a modified nucleotide with an 18-oxygen atom in the 2' position, which prevents its use as a substrate for phosphodiesterases, thereby increasing its stability in vivo. [2'-18O]Guanosine is synthesized from the corresponding ribonucleotide, guanosine monophosphate (GMP), and can be used as an activator for DNA synthesis and an inhibitor of RNA synthesis.Formula:C10H13N518OO4Purity:Min. 95%Molecular weight:285.24 g/mol7-Iodo-7-deaza-2'-C-methylguanosine
7-Iodo-7-deaza-2'-C-methylguanosine has antiviral activity and is used as a building block in the synthesis of DNA and RNA molecules. 7-Iodo-7-deaza-2'-C-methylguanosine is a novel synthetic nucleoside that has anticancer properties and is used for the treatment of different types of cancer. It is also used for the prevention of viral infections, such as influenza. This product has high purity and is available in its phosphate or monophosphate form.Purity:Min. 95%3'-Amino-2',3'-dideoxyinosine
CAS:3'-Amino-2',3'-dideoxyinosine acts as a chain terminator in DNA synthesis due to the absence of a 3'-hydroxyl group. The 3'-amino group allows for the attachment of various molecules to the 3' end of oligonucleotides, and the inosine base introduces the potential for wobble base pairing, making it a specialized tool for research and potential diagnostic applications.Formula:C10H13N5O3Purity:Min. 95%Molecular weight:251.24 g/mol3'-Deoxyguanosine
CAS:3'-Deoxyguanosine is a nucleic acid that is involved in the synthesis of polysaccharides and proteins. It has been shown to have an inhibitory effect on the synthesis of collagen, which may be due to its ability to increase hydrogen bonding between the nitrogen atoms and oxygen atoms. 3'-Deoxyguanosine has also been shown to have a protective effect on wheat germ extract, which may be due to its ability to inhibit oxidation reactions. The chemical structure of 3'-deoxyguanosine can be synthesized by reacting deoxyribose with sodium nitrate in the presence of sulfuric acid. This reaction can be monitored using electrochemical impedance spectroscopy (EIS).Formula:C10H13N5O4Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:267.25 g/molN6,7-Dimethyldeoxyadenosine
N6,7-Dimethyldeoxyadenosine is a nucleoside with antiviral and anticancer properties. It is a modified DNA monophosphate with the chemical formula C8H16N2O6P. N6,7-dimethyldeoxyadenosine has been shown to inhibit the replication of HIV and herpes simplex virus type 1 (HSV-1) in vitro. This compound also inhibits the growth of cancer cells in culture and has been suggested as an anticancer therapeutic agent.Purity:Min. 95%N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
CAS:Nucleoside phosphoramidites are widely used as building blocks in the chemical synthesis of oligonucleotides. The use of a chemical synthesis rather than an enzymatic one allows bespoke oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with the 5’ hydroxyl of the next nucleoside in the desired sequence. The reaction is usually catalysed by 1H-tetrazole or 4,5-dicyanoimidazole in acetonitrile. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, also called N4-Bz-5'-DMT-5-Me-dC phosphoramidite, is used in the synthesis of 2’-deoxy-5-methylcytidine-containing oligonucleotides as antisense drugs.Formula:C47H54N5O8PPurity:Min. 95%Color and Shape:White PowderMolecular weight:847.93 g/mol9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine
9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine is an oligonucleotide with a fluorinated nucleobase that is used to stabilize DNA duplexes. It is synthesized from 5'-deoxy-5'-fluorocytidine, which is a phosphoramidite, and 2',3',5'-triacetylpyrimidine, which is a substituent. The deprotection of the fluorinated oligonucleotide can be achieved by treatment with sodium hydroxide in ethanol or hydrochloric acid in acetic acid. 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine has been shown to be stable and antiparallel when incorporated into double stranded DNA molecules.Formula:C10H12FN5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.24 g/mol2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyluridine
2′-O-Acetyl-3′-deoxy-3′-fluoro-5′-O-toluoyluridine is a novel, activator ribonucleoside. It is synthesized by the phosphoramidite method and modified with an acetyl group at the 2′ position and a toluoyl group at the 3′ position. This compound has been shown to be active against cancer cells in vitro and in vivo.Formula:C19H19FN2O7Purity:Min. 95%Molecular weight:406.36 g/mol5’(R)-C-Methyl-5-methyluridine
CAS:5’(R)-C-Methyl-5-methyluridine is an nucleoside and a ribonucleoside. It has antiviral, anticancer, and DNA modifying properties. This product is used in research to make phosphoramidites, diphosphates, and deoxyribonucleosides. 5’(R)-C-Methyl-5-methyluridine is also used in the production of modified oligonucleotides as well as other novel DNA compounds.
Purity:Min. 95%N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:N6-Benzoyl-2'-deoxy-5'-O-DMT adenosine 3'-CE phosphoramidite is a protected adenosine amidite.Formula:C47H52N7O7PPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:857.93 g/mol5'-O-p-Anisoylthymidine
5'-O-p-Anisoylthymidine is a novel activator and ribonucleoside that has been synthesized by modifying the structure of thymidine. This compound is active against cancer and antiviral, such as herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, influenza A/PR/8/34 (H1N1), and influenza B/Yamagata/16/88. 5'-O-p-Anisoylthymidine activates viral transcription in cells infected with these viruses by inhibiting the synthesis of deoxyribonucleosides. It also inhibits DNA synthesis by inhibiting the incorporation of deoxyribonucleotides into DNA during replication. This product is CAS No. 138581-03-2 and comes in high purity and high quality.Formula:C18H20N2O7Purity:Min. 95%Molecular weight:376.36 g/molN6-Benzoyl-3’-deoxy-5'-O-DMT-3’- fluoroadenosine 2’-CE-phosphoramidite
N6-Benzoyl-3’-deoxy-5'-O-DMT-3’- fluoroadenosine 2’-CE-phosphoramidite is a novel and activator ribonucleoside with deoxyribonucleosides, diphosphate and phosphoramidites. It is an anti-cancer, antiviral, and antiinflammatory agent. N6-Benzoyl-3’-deoxy-5'-O-DMT-3’ -fluoro adenosine 2’ -CE phosphoramidite has a CAS no.Purity:Min. 95%Denufosol tetrasodium
CAS:A P2Y2 receptor agonist that has been studied in cystic fibrosis and retinal diseases such as retinal detachment. Denufosol was studied as an inhaled drug for cystic fibrosis, due to its ability to activate an alternative chloride channel and avoiding the defective CFTR chloride channel. This enhances hydration of the lung mucosa and improves mucociliary clearance. The drug did not progress from phase III clinical trials. Denufosol resulted in subretinal fluid reabsorption in in vivo model of retinal detachment.
Formula:C18H23N5Na4O21P4Purity:Min. 90 Area-%Color and Shape:PowderMolecular weight:861.25 g/mol5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine
CAS:5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine is a nucleoside that has been synthesized using an oxime opening of the 5' position and a methylation at the 2' position. It has been shown to have an affinity for tissues in a chemotactic assay. The compound is minimised to remove non-specific binding sites, avoiding false positives on the checklist. This molecule has been analysed with fluorescence spectroscopy and microscopy techniques, which revealed that it is distributed in tissues as well as being found in dragonflies. It was also shown to be transduced by muscle cells and geochemically detected in limestone from China.Formula:C36H39N5O8Purity:Min. 95%Color and Shape:PowderMolecular weight:669.74 g/mol8-Hydrazinoadenosine
CAS:8-Hydrazinoadenosine is an inhibitor of phosphodiesterase, which is a key enzyme in the regulation of cellular processes. 8-Hydrazinoadenosine binds to the active site of the enzyme and inhibits its function. This binding prevents hydrolysis of the phosphate bond between two nucleotides and so prevents the formation of a new nucleotide from a nucleoside and a phosphate molecule. 8-Hydrazinoadenosine has been shown to inhibit phosphodiesterases in vitro and in animals, including rat brain and mouse lung. Strategies for 8-hydrazinoadenosine commercialization have been investigated, including attaching it to other molecules that are more easily absorbed by cells or using irradiation to produce 8-aminoadenosine, which can be converted into 8-hydrazinoadenosine.Purity:Min. 95%8-Chloroadenosine
CAS:8-Chloroadenosine is a potent inhibitor of apoptosis, which is the process by which cells die. It has been shown to inhibit cell growth in murine hepatoma cells and synergize with other cytotoxic agents. 8-Chloroadenosine inhibits the activity of bcl-2 protein and thus blocks the release of cytochrome c from mitochondria. This causes DNA damage by inhibiting DNA synthesis and protein synthesis, leading to apoptosis. 8-Chloroadenosine has also been shown to be an active inhibitor of cancer cells, especially myeloma cell lines. The response element for 8-chloroadenosine is located in the promoter region of the gene encoding cyclooxygenase 2 (COX-2), which encodes a protein that produces prostaglandins involved in inflammation and tumor growth. The concentration of camp in cancer tissues determines whether these cells will respond favorably or unfavorably to this drug.Formula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/mol5-Hydroxymethyl-2’-O-(2-methoxyethyl)uridine
CAS:5-Hydroxymethyl-2’-O-(2-methoxyethyl)uridine (5HMEU) is a nucleoside that is synthesized from 2’,3’-dideoxyribonucleosides. 5HMEU has been shown to be an activator of the human telomerase enzyme and is used in the synthesis of DNA. It also has anticancer properties and can inhibit the growth of various cancer cells, including pancreatic, breast, prostate, lung, liver, and cervical cancer cells. 5HMEU is a modified nucleoside that contains a hydroxyl group at the 2’ position and an methoxyl group at the 5’ position. The chemical name for 5HMEU is 5-hydroxymethyl-2'-O-(2-methoxyethyl)uridine.Purity:Min. 95%EdU
CAS:2'-Deoxy-5-ethynyluridine (5-EdU) is a modified thymidine analogue containing a terminal alkyne group, which is used for nucleotide labelling. 5-Edu is easily taken up by cells and incorporated by metabolic activation during DNA synthesis. By adding an azide conjugated to a fluorophore or a biotin moiety, a click reaction occurs from the labelled nucleotide linked by a triazole group. 5-Edu are employed in cell proliferation assays, to study DNA and RNA localisation, structure and dynamics, in the synthesis of aptamers with the click-SELEX method, and in other applications such as the preparation of oligonucleotide microarrays and nanoelectronic devices.Formula:C11H12N2O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:252.23 g/molQueuine hydrochloride
CAS:Queuine is a modified nucleoside found in tRNA. It is synthesized from guanosine by the enzyme queuine tRNA-ribosyltransferase, which converts guanosine to queuosine. Queuine hydrochloride is a synthetic form of queuine that can be used for research purposes to examine the anticodon loop and other structural features of the molecule. The prokaryotic and eukaryotic organisms studied showed different levels of synthesis of queuine, with bacteria synthesizing more than mammals. Bacteria were found to have a greater affinity for queuine than eukaryotes, which may be due to modification of the trna anticodon loop or to differences in ribosomal proteins.Formula:C12H15N5O3·HClPurity:(%) Min. 90%Color and Shape:Light (Or Pale) Beige To Light (Or Pale) Purple SolidMolecular weight:313.74 g/mol2'-C-Methylcytidine
CAS:Broad-spectrum anti-viral; inhibitor of HCV NS5B RNA polymeraseFormula:C10H15N3O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:257.25 g/molPolyinosinic acid-polycytidylic acid, homopolymer (1:1)
CAS:Polyinosinic acid-polycytidylic acid (Poly I:C), an agonist of TLR3 toll-like receptors, is a synthetic double-stranded RNA analog, consisting of polyinosinic acid (poly I) paired with polycytidylic acid (poly C), forming a stable duplex structure.PolyI:C stimulates the secretion of pro-inflammatory cytokines and type I interferon through its interaction with endosomal Toll-like receptor 3 (TLR-3) and the cytoplasmic receptors melanoma differentiation-associated gene 5 (MDA-5) and retinoic acid-inducible gene I (RIG-I). This immunostimulant activity makes Poly I:C a useful vaccine adjuvant and is used in vaccine formulations. Poly I:C and its stabilized analogs (e.g., poly-ICLC) are also being actively researched for their dual role in oncology: directly targeting tumors and acting as immune potentiators. For example Poly I:C can induce apoptosis in tumor cells and stimulate immunogenic cell death and is therefore being explored alongside chemotherapy, radiotherapy, and checkpoint inhibitors, helping to overcome resistance mechanisms and strengthen treatment outcomes.We can supply PolyI:C to all stages of your project - from R&D and preclinical phases right up to GMP commercial manufacture. Contact our team for custom Poly I:C products. For more on poly I:C read out blog 'Poly I:C: A Vaccine Adjuvant With Oncological Potential.'Formula:(C10H13N4O8P)x•(C9H14N3O8P)xColor and Shape:PowderL-Thymidine
CAS:L-Thymidine is an antiviral drug that is used in the treatment of chronic hepatitis. It has been shown to be active against a range of viruses, including HIV, HSV, and HBV. L-Thymidine can also be used to treat patients with cancer as an anti-cancer agent. L-Thymidine is a prodrug that is converted into thymidine triphosphate (TTP), which inhibits viral DNA polymerase by competitive inhibition. The antiviral activity of L-Thymidine may be due to its ability to inhibit the synthesis of viral proteins required for viral replication by interfering with the protein production process or by inhibiting the formation of dsDNA during reverse transcription.Formula:C10H14N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:242.23 g/molN4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine
CAS:N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a synthetic nucleoside that is used as an activator for DNA synthesis. It is also used in the preparation of diphosphate derivatives for use as antiviral and anticancer agents or as probes for DNA and RNA research. N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a novel, high purity, and high quality chemical with CAS No. 86234-45-9.
Formula:C37H35N3O7Purity:Min. 95%Molecular weight:633.69 g/mol2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is a nucleoside that is used in the synthesis of DNA. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is an antiviral, antineoplastic, and anticancer agent. It has been shown to be active against some strains of HIV and herpes viruses. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt also inhibits DNA polymerase and RNA polymerase, preventing viral replication and transcription. The phosphate group on the 5' end of this molecule can be modified to produce phosphoramidites, diphosphates, or triphosphates.Formula:C9H11FN3O13P3·Li4Purity:Min. 95%Molecular weight:508.88 g/mol1-Methylpseudouridine
CAS:1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).Formula:C10H14N2O6Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:258.23 g/mol2-[(Benzo[b]thien-2-ylcarbonyl)amino]benzoic acid
CAS:2-[(Benzo[b]thien-2-ylcarbonyl)amino]benzoic acid is a benzoic acid derivative for use in researchFormula:C16H11NO3SPurity:Min. 95%Color and Shape:PowderMolecular weight:297.33 g/molGuanosine 3', 5'- bisdiphosphate lithium salt
CAS:Regulates gene transcription; inhibits the synthesis of tRNA and rRNAFormula:C10H17N5O17P4·xLiPurity:Min. 95%Molecular weight:603.16 g/mol2,8-Dimethyladenosine
CAS:2,8-Dimethyladenosine is a methylated derivative of the purine nucleoside adenosine, in which methyl groups are added at the 2-position and 8-position of the adenine base.Formula:C12H17N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:295.29 g/mol5-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:5-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a novel nucleoside and phosphoramidite activator. It is synthesized from 2'-deoxyadenosine, 5'-chloropurine riboside, and 1,1'-bis(diisopropylphosphino)ferrocene. This compound has been shown to be an effective antiviral and anticancer agent in vitro.Formula:C12H15ClN4O4Purity:Min. 95%Molecular weight:314.72 g/mol7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine
CAS:7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine is a novel modified ribonucleoside. It has the ability to activate DNA at the monophosphate level and can be used as a substrate for DNA polymerase and in the synthesis of deoxyribonucleosides. 7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine also has antiviral properties, which may be due to its inhibition of viral RNA synthesis. The compound is also used in anticancer treatment as it inhibits cellular proliferation by inhibiting DNA synthesis.
Purity:Min. 95%5'-O-tert-Butyldimethylsilyl-2'-deoxyuridine
5'-O-tert-Butyldimethylsilyl-2'-deoxyuridine (5'-O-TBDMSU) is a modified nucleoside that has antiviral, anticancer and novel activities. It is synthesized by the reaction of 5'-O-tert-butyldimethylsilyl-2'-deoxyuridine with methyl chloroformate. 5'-O-TBDMSU has been shown to inhibit viral replication in cell culture. The antiviral activity of 5'-O-TBDMSU may be due to its ability to inhibit DNA synthesis by inhibiting the incorporation of deoxyribonucleotide triphosphates into DNA or by inhibiting the activity of DNA polymerases. This compound also inhibits the replication of RNA viruses such as HIV and hepatitis C virus, which are dependent on deoxyribonucleosides for their replication.Formula:C15H26N2O5SiPurity:Min. 95%Molecular weight:342.47 g/mol5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine
5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine is a novel nucleoside that is synthesized from ribonucleosides. It is an inhibitor of the RNA polymerase enzyme, which prevents the transcription and replication of DNA. 5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine also inhibits viral DNA synthesis by preventing viral RNA from being translated into DNA. This product has been shown to be active against a wide range of viruses, including influenza A virus, herpes simplex virus type 1, and vaccinia virus.Formula:C16H15FN2O5Purity:Min. 95%Molecular weight:334.35 g/mol3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine
3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is a modified nucleoside that is synthesized by the phosphoramidite method. It is a novel antiviral drug with anticancer properties. This active compound has been shown to be an activator of ribonucleotide reductases, which are enzymes that catalyze the conversion of ribonucleotides to deoxyribonucleotides. 3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is not cytotoxic at concentrations up to 40 mM, and it has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV) in tissue culture.Purity:Min. 95%1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine
1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine is a deoxyribonucleoside monophosphate with antiviral effects. It is a novel nucleotide analogue that contains an azido group and a 2,4,6-trifluorobenzene moiety. The 4′ position of the sugar is modified with an n-docosanoyl group. 1-(4’Azo-2′deoxy-2′fluoro-bDara)ribonucleosides are synthetic nucleotides that can be used to inhibit viral replication by inhibiting DNA polymerase and RNA polymerase.Purity:Min. 95%5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:5'-O-DMT-uridine 3'-CE phosphoramidite is a novel, modified and activator nucleoside. It can be used as an antiviral agent or in the synthesis of DNA. 5'-O-DMT-uridine 3'-CE phosphoramidite has been shown to be cytotoxic in vitro to cancer cells.Formula:C39H47N4O9PPurity:Min. 95%Molecular weight:746.79 g/mol8-Azidoadenosine
CAS:8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.
Formula:C10H12N8O4Purity:Min. 95%Color and Shape:PowderMolecular weight:308.25 g/mol2',3'-Dideoxy-5-methylcytidine
CAS:2',3'-Dideoxy-5-methylcytidine is a synthetic nucleoside analog based on cytidine, a natural building block of DNA and RNA. This molecule is chemically modified to interfere with nucleic acid synthesis, making it a potential tool in antiviral or anticancer therapy, or for studying epigenetics.Formula:C10H15N3O3Purity:Min. 95%Color and Shape:PowderMolecular weight:225.25 g/molN2,N2,7-Trimethylguanosine
CAS:Trimethylguanosine is a hydrogen-bonded base that is found in the DNA of all living organisms. It has a diagnostic role in cancer and metabolic disorders, as well as in the study of cell culture. Trimethylguanosine can be used to identify cancer cells by measuring its fluorescence properties, which are different from those of healthy cells. This compound also has a role in the diagnosis of metabolic disorders, such as diabetes mellitus and renal disease. Trimethylguanosine is also involved in biological function, and is necessary for the synthesis of proteins and nucleic acids.Formula:C13H20N5O5Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:326.33 g/molAdenine
CAS:Adenine is a nucleobase found in DNA and RNA. It is an essential component of the human body and is used in the production of phosphoramidites, which are chemical compounds that can be converted into phosphodiester bonds. Adenine has been shown to have anticancer properties, and it may function as a novel activator for other anticancer drugs. Adenine is also used as a monophosphate in some cases. The purity of this compound exceeds 99% and the molecular weight ranges from 162 to 166.5 Daltons.
Formula:C5H5N5Purity:Min. 98.0 Area-%Molecular weight:135.13 g/molN4,3'-O-Dibenzoyl-2'-deoxycytidine
CAS:N4,3'-O-Dibenzoyl-2'-deoxycytidine is a nucleoside that functions as a base. It is a diester of the naturally occurring nucleoside cytidine and 2′,6′-dibenzoyl-deoxyribose. The compound has been shown to be an inhibitor of DNA polymerases and nuclease activity in vitro. N4,3'-O-Dibenzoyl-2'-deoxycytidine has been shown to inhibit the growth of certain strains of bacteria and can be used for the treatment of tuberculosis. This drug also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. !-- END OF PRODUCT DESCRIPTIONS -->Formula:C23H21N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:435.44 g/mol2'-Deoxy-5'-O-DMT-5-iodouridine
CAS:2'-Deoxy-5'-O-DMT-5-iodouridine is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.Formula:C30H29IN2O7Purity:Min. 95%Color and Shape:PowderMolecular weight:656.48 g/molN6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite
N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite is a novel nucleoside that has antiviral and anticancer properties. It is an analog of adenosine and inhibits the action of ribonucleotide reductase, which is an enzyme that converts ribonucleotides to deoxyribonucleotides. N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite also inhibits the synthesis of DNA, which may be due to its inhibition of DNA polymerase. This compound has been shown to inhibit the growth of leukemia cells in culture and induce apoptosis in human tumor cells.
Formula:C47H51FN7O7PPurity:Min. 95%Molecular weight:875.92 g/mol6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.Formula:C10H12N4O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:268.29 g/mol4-Hydroxy-6-methylpyrimidine
CAS:4-Hydroxy-6-methylpyrimidine (4-OHMP) is a metabolite of trimethyltin. It is formed in the liver by methylation of 4,6-dimethylpyrimidine (4,6-DMPU). The levels of 4-OHMP in urine samples are used to monitor exposure to this agent. The median values for urinary concentrations of 4-OHMP are typically 10 times higher than those found in blood samples. The metabolite can be detected in urine up to 2 weeks after an individual’s last contact with trimethyltin. This compound has been shown to inhibit the synthesis of glycol dimethyl ethers and carbamates.
Formula:C5H6N2OPurity:Min. 95%Molecular weight:110.11 g/mol1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt
1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is an Activator for the synthesis of DNA and RNA. It is a novel synthetic nucleoside that has anticancer activity. 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is used as an antiviral agent, inhibiting viral replication by blocking the RNA polymerase enzyme.Formula:C9H13FN2O14P3·C6H16NPurity:Min. 95%Molecular weight:587.32 g/mol2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt
2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt is a nucleoside that can be used in the synthesis of DNA and RNA. It is a synthetic, high quality, and novel compound that has been shown to have antiviral, anticancer, and anti-inflammatory properties. This compound has been shown to inhibit the growth of cancer cells by inhibiting the production of proteins vital for cell division. 2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt has also been shown to be an activator of nucleoside phosphorylase and deoxynucleotide kinase, which are enzymes that catalyze the conversion of nucleosides into their corresponding monophosphates.Purity:Min. 95%7-Deaza-2'-deoxyadenosine
CAS:7-Deaza-2'-deoxyadenosine is an oligodeoxynucleotide analog that has been shown to be a potent inhibitor of human ovarian carcinoma cells. It inhibits the uptake of organic anion transporters, which are proteins found in the cell membrane that transport organic anions such as nucleosides and nucleotides. 7-Deaza-2'-deoxyadenosine has also been shown to inhibit DNA synthesis and polymerase chain reactions by binding to the enzyme RNA polymerase II. This drug can be synthesized with solid phase chemistry, making it a highly reproducible product.Formula:C11H14N4O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:250.26 g/molAdenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution
CAS:Adenosine-5'-O-(1-thiotriphosphate) lithium salt is an inhibitor of the guanine nucleotide-binding protein that is reversibly inhibited by adenosine triphosphate. It has been shown to inhibit HIV infection by binding to the Ryanodine receptor and blocking the release of calcium ions from intracellular stores. This prevents the activation of caspases, which are enzymes that cause cell lysis. Adenosine-5'-O-(1-thiotriphosphate) lithium salt also blocks transcription and polymerase chain reactions, and may inhibit the growth of cancer cells by inhibiting epidermal growth factor receptors on the cell surface.Formula:C10H12Li4N5O12P3SPurity:Min. 95%Color and Shape:PowderMolecular weight:546.98 g/molb-Nicotinamide adenine dinucleotide phosphate
CAS:Coenzyme and regenerating electron donor in catabolic processesFormula:C21H28N7O17P3Purity:Min. 80 Area-%Color and Shape:Off-White PowderMolecular weight:743.41 g/mol2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt
CAS:2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt is a nucleoside that can be used as an antiviral or anticancer drug. It is a modified nucleoside, which is synthesized by phosphoramidite chemistry. 2'-O-Methyl-5'-methyluridine 5'-triphosphate triethylammonium salt has been shown to be an activator of DNA polymerase in vitro and in vivo. It also has high purity and high quality.Formula:C11H19N2O15P3Purity:Min. 95%Molecular weight:512.19 g/mol8-Chloro-2'-deoxyguanosine
CAS:8-Chloro-2'-deoxyguanosine is a reactive oxygen species that can cause oxidative damage to DNA. This compound is generated by the hypochlorous acid (HOCl) in cells and can be found in human tissues. 8-Chloro-2'-deoxyguanosine can also be generated by the HOCl in diabetic patients, where it has been shown to cause oxidative damage to DNA. 8-Chloro-2'-deoxyguanosine is a product of the reaction between hydrogen peroxide and catalase, and it is activated by HOCl. It has been shown to be carcinogenic in animal models, where it causes DNA damage that leads to cancer.Formula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/mol5-Amino-2’-deoxy-2’-O-methyluridine HCl
5-Amino-2’-deoxy-2’-O-methyluridine HCl is a novel nucleoside analog that has been modified with an O-methyl group at the 5′ position of the ribose moiety. This modification inhibits phosphorylation by inhibiting DNA polymerase and thus, preventing DNA synthesis. 5-Amino-2’-deoxy-2’-O-methyluridine HCl has also been shown to inhibit viral replication by inhibiting viral RNA and protein synthesis, while not affecting human RNA and protein synthesis. 5AADMUT is an activator of diphosphate metabolism in cells which may be due to its ability to inhibit enzymes involved in nucleotide metabolism (e.g., adenosine kinase).Purity:Min. 95%Ribavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS:Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.Formula:C8H15N4O14P3·Na4Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:576.1 g/molN6-Carbamoylthreonyladenosine sodium salt
CAS:N6-Carbamoylthreonyladenosine sodium salt is a fatty acid that is found in the bacterial cell wall. It has been shown to be an essential component of the cell wall for Gram-positive and Gram-negative bacteria. N6-Carbamoylthreonyladenosine sodium salt has been used to study the mechanism of protein synthesis in bacteria, especially how enzymes are involved in this process. Chemical biology studies have shown that this molecule can bind to DNA and inhibit bacterial growth. The crystal structure of N6-Carbamoylthreonyladenosine sodium salt has also been determined using x-ray diffraction data. This molecule inhibits the binding of proteins to DNA, which prevents transcription and replication. The reaction mechanism involves hydrogen bonding between the oxygen atoms on N6-Carbamoylthreonyladenosine sodium salt and divalent metal ions such as magnesium or zinc, which are required for protein synthesis.Formula:C15H19N6O8·NaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:434.34 g/mol2’-Deoxy-N4-dimethylcytidine
CAS:2’-Deoxy-N4-dimethylcytidine is a synthetic nucleoside analog that is used to inhibit viral replication in the treatment of AIDS and cancer. It is phosphorylated by adenosine kinase to form deoxydimethylcytidine monophosphate (dDMP), which inhibits viral DNA synthesis by inhibiting the activity of reverse transcriptase, an enzyme involved in the production of viral DNA. 2’-Deoxy-N4-dimethylcytidine has also been shown to inhibit cancer cell growth by interrupting mitosis and inducing apoptosis.Purity:Min. 95%3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine
3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that inhibits DNA synthesis by competitively inhibiting the activity of deoxycytidine kinase. 3'-Amino-5'-O-p-anisoyl-N4-benzoyl-2',3'-dideoxycytidine is an antiviral agent and has been shown to be effective against herpes simplex virus type 1 and varicella zoster virus. It has also been shown to have anticancer properties, which may be due to its ability to inhibit the growth of human breast cancer cells in culture.Formula:C24H24N4O6Purity:Min. 95%Molecular weight:464.47 g/mol2-Azidoadenosine
CAS:2-Azidoadenosine is a nucleoside analog of adenosine, where the 2'-hydroxyl group of the ribose sugar is replaced with an azido group (–N₃). This substitution imparts unique chemical properties, notably enabling molecules to undergo bioorthogonal reactions, such as click chemistry, which involves the cycloaddition of the azide group with alkynes.
Formula:C10H12H8O4Purity:Min. 95%Color and Shape:PowderMolecular weight:308.25 g/mol2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine
2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine is a novel modified nucleoside with antiviral and anticancer activities. It is synthesized from 2'-deoxyuridine monophosphate, which is activated with bis(trimethylsilyl)acetamide (BSA). This nucleoside has been shown to inhibit the growth of cancer cells in vitro and in vivo.Purity:Min. 95%Trifluorothymidine
CAS:Treats herpes-associated keratitis and keratoconjunctivitis; antineoplasticFormula:C10H11F3N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:296.2 g/molUridine 5'-monophosphate
CAS:Uridine 5'-monophosphate (UMP) is a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. UMP has been shown to inhibit the protein synthesis of cells by inhibiting the enzyme activities of DNA polymerase and RNA polymerase. It also inhibits the synthesis of p2y receptors, which are involved in cell proliferation and differentiation. Further studies suggest that UMP may be an effective anti-inflammatory agent due to its ability to decrease prostaglandin production.Formula:C9H13N2O9PPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:324.18 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a novel modified ribonucleoside that has been synthesized to mimic the natural nucleotide. It has been shown to activate DNA synthesis, inhibit cancer cell division and proliferation, and inhibit viral replication. 2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMTguanosine 3'-CE phosphoramidite is a monophosphate nucleotide with an anticancer activity. It has also showed antiviral effects against HIV and Hepatitis B virus. This novel modified ribonucleoside is highly pure and can be used for the synthesis of high quality DNA, RNA, or phosphoramidites.Formula:C49H66N7O8PSiPurity:Min. 95%Molecular weight:940.17 g/molb-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium)
CAS:b-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium), or NADPH, is involved in redox reactions, where it acts as an electron donor. NADPH is essential for anabolic reactions, such as lipid and cholesterol biosynthesis, and fatty acid chain elongation. It also plays a significant role in antioxidation mechanisms, protecting cells from oxidative stress by neutralizing reactive oxygen species (ROS) and regenerating antioxidants like glutathioneFormula:C21H30N7O17P3·4C6H13NPurity:Min. 90 Area-%Color and Shape:Slightly Yellow PowderMolecular weight:1,142.12 g/mol5'-O-p-Anisoyl-2,2'-anhydrouridine
5'-O-p-Anisoyl-2,2'-anhydrouridine is a novel nucleoside. It is an activator of ribonucleosides and deoxyribonucleosides. This compound has antiviral activity against HIV and DNA synthesis inhibitory activity against cancer cells. 5'-O-p-Anisoyl-2,2'-anhydrouridine is also a modified nucleoside that can be used for the synthesis of phosphoramidites for the chemical synthesis of oligodeoxynucleotides (ODN).Formula:C17H16N2O7Purity:Min. 95%Molecular weight:360.32 g/mol3-Deaza-2'-O-methyluridine
CAS:3-Deaza-2'-O-methyluridine is a nucleoside that is used as an antiviral agent and in the treatment of leukemia. It has been shown to inhibit the growth of L1210 cells in a dose-dependent manner. 3-Deaza-2'-O-methyluridine also inhibits the synthesis of DNA, RNA, and proteins. The compound is eliminated by renal excretion with a plasma elimination half life of 9 hours. This drug can be administered intramuscularly or intravenously at a dosage of 10 mg/kg every 8 hours, but should not be given more than 5 days without interruption due to accumulation in tissues.
Formula:C11H15NO6Purity:Min. 95%Molecular weight:257.24 g/mol5'-O-DMT-α-thymidine
5'-O-DMT-a-thymidine is a modified nucleoside that is used in the synthesis of DNA and RNA. This product is a high quality and pure monophosphate, which has been modified to reduce its potential for activation by phosphatases. It is suitable for use in anticancer drugs and antiviral agents.
Formula:C31H32N2O7Purity:Min. 95%Molecular weight:544.6 g/mol2',3',5'-Tri-O-benzoyl-N6-benzyl-2'-C-methyladenosine
CAS:2',3',5'-Tri-O-benzoyl-N6-benzyl-2'-C-methyladenosine is an adenosine analog for potential use in research into antiviral drug development or nucleoside analogs.Formula:C39H33N5O7Purity:Min. 95%Color and Shape:PowderMolecular weight:683.71 g/mol2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine
CAS:2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.Purity:Min. 95%3'-Deoxythymidine
CAS:3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.Formula:C10H14N2O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:226.23 g/mol3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine
CAS:Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt
CAS:N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is a novel modified nucleoside with anticancer activity. The compound is a monophosphate, which activates DNA and RNA synthesis. This agent also has antiviral and antifungal effects. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is synthesized from diphosphate and deoxyribonucleosides. It was first patented in 1979 and has been approved by the US Food and Drug Administration (FDA) for use as a pharmaceutical agent. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt can be used to produce phosphoramidites, which are synthetic DNA building blocks that are used in the production of DNA and RNA synthesis.Formula:C13H16N4O9Na2Purity:Min. 95 Area-%Color and Shape:Off-White PowderMolecular weight:418.27 g/molN6-Benzoyl-2',3'-isopropylideneadenosine
CAS:N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.
Formula:C20H21N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:411.41 g/mol2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine
CAS:2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine is a modified nucleoside that is used as an anticancer drug. It is synthesized from 2’,3’,5’triphosphate and 2’C-methyl-5-methoxyuridine. This compound is used to treat leukemia and other cancers by inhibiting the synthesis of DNA. Inhibiting DNA synthesis prevents the reproduction of cancer cells. The chemical structure of this compound was first published in 2007.Purity:Min. 95%2'-Deoxyadenosine 3'-O-L-valinyl ester
2'-Deoxyadenosine 3'-O-L-valinyl ester is a novel nucleoside phosphoramidite that is synthesized by activating the 2'-deoxyribose phosphate with an L-valyl chloride. This synthetic nucleoside analog can be used as a substitute for dATP in DNA synthesis and has antiviral as well as anticancer activities.Purity:Min. 95%5'-O-tert-Butyldimethsilyl-2'-Deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite
5'-O-tert-Butyldimethsilyl-2'-Deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel nucleoside analog with antiviral and anticancer properties. It is a modified nucleoside that is synthesized by reacting 5'-O-tert-butyldimethylsilyl guanosine with 2'-deoxyisobutyryl chloride in the presence of triethylamine. The resulting 5'-O-tert-butyldimethylsilyl-2'-deoxyisobutyrylguanosine 3'-CE phosphoramidite has been shown to be cytotoxic to tumor cells without affecting normal cells.Formula:C29H50N7O6PSiPurity:Min. 95%Molecular weight:651.82 g/mol1-(b-L-Threonyl)uracil
1-(b-L-Threonyl)uracil is a novel anticancer drug that has been synthesized with the aim of increasing the efficacy of DNA synthesis. The incorporation of this nucleoside in the DNA chain prevents the formation of ribonuclesides, which are inhibitory to DNA synthesis. It also inhibits viral replication and can be used as a treatment for HIV infection. 1-(b-L-Threonyl)uracil is synthesized by reacting b-L-threonyl chloride with uracil in the presence of a base and a catalytic amount of thiourea. This product is used in biotechnology as an activator for phosphoramidites and modified nucleosides.Purity:Min. 95%3’-Azido-3’-deoxy-b-L-adenosine
CAS:3’-Azido-3’-deoxy-b-L-adenosine is a novel nucleoside that has been synthesized to be used as an antiviral agent. It is phosphorylated, which allows it to be activated by adenosine kinase, and is thus able to inhibit viral replication and spread. 3’-Azido-3’-deoxy-b-L-adenosine is effective against various viruses, including HIV, herpes simplex virus type 1 (HSV1), and hepatitis C virus (HCV). This nucleoside also has anticancer activity due to its ability to inhibit the synthesis of DNA and RNA. It has been modified from the natural nucleosides with the addition of a 2′,3′ azido group at the 3 position on the ribose sugar. The modification prevents viral resistance because it does not require activation by cellular kinases or phosphorylation in order to be active.Purity:Min. 95%3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine
CAS:Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%N6-Benzoyl-2'-C-methyladenosine
N6-Benzoyl-2'-C-methyladenosine is synthetic and has antiviral properties. It is a nucleoside that belongs to the group of modified nucleosides. This compound can be used as an activator for DNA synthesis and as a novel monophosphate, diphosphate, or triphosphate. N6-Benzoyl-2'-C-methyladenosine is also available in high purity, with CAS No., and at a competitive price.Purity:Min. 95%
![Guanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNG46689.webp&w=3840&q=75)
![4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNA167989.webp&w=3840&q=75)
![4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FND162980.webp&w=3840&q=75)
![[2'-18O]Guanosine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNG106386.webp&w=3840&q=75)
![2-[(Benzo[b]thien-2-ylcarbonyl)amino]benzoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNB181580.webp&w=3840&q=75)
![5-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNC14096.webp&w=3840&q=75)
![7-b-D-Ribofuranosyl-7H- tetrazolo[5,1i]purine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNR163016.webp&w=3840&q=75)
