G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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MLS1547
CAS:315698-36-3
MLS1547 is a potent D2 receptor G protein-biased agonist (Ki=1.2 μM, EC50=0.37 μM in Ca2+ …
Formula:
C19H19ClN4O
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
354.83
Ref: TM-T28073
| 10mg | 41.00 € | ||
| 25mg | 56.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
Barbadin
CAS:356568-70-2
Barbadin is an inhibitor of β-arrestin/β2-adaptin interaction.Barbadin enhances the effects of lorcaserin on weight loss …
Formula:
C19H15N3OS
Purity:
98.93%
Color and Shape:
Solid
Molecular weight:
333.41
Ref: TM-T14498
| 1mg | 189.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
RS 56812 hydrochloride
CAS:143339-12-2
5-HT3 partial agonist
Formula:
C18H22ClN3O2
Purity:
97.69%
Color and Shape:
Solid
Molecular weight:
347.84
Ref: TM-T23264
| 1mg | 64.00 € | ||
| 2mg | 90.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 431.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
PF2562
CAS:1609258-91-4
PF2562: Dopamine D1 ligand, agonist/partial agonist. Binds D1 receptor (Ki: 113 nM), active in cAMP …
Formula:
C19H17N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
331.37
Ref: TM-T16511
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
Tiopinac
CAS:61220-69-7
Tiopinac: tricyclic with anti-inflammatory, analgesic, antipyretic properties; inhibits prostaglandin synthesis; mild anti-platelet effects in humans.
Formula:
C16H12O3S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
284.33
Ref: TM-T17101
| 1mg | 197.00 € | ||
| 5mg | 497.00 € | ||
| 10mg | 707.00 € | ||
| 25mg | 1,059.00 € | ||
| 50mg | 1,437.00 € | ||
| 100mg | 1,872.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
GR 113808
CAS:144625-51-4
GR 113808 is a 5-HT4 receptor antagonist that inhibits 5-HT1B and 5-HT3 receptors and attenuates …
Formula:
C19H27N3O4S
Purity:
98.16%
Color and Shape:
Solid
Molecular weight:
393.5
Ref: TM-T15414
| 1mg | 38.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
MK-0249
CAS:862309-06-6
MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).
Formula:
C23H24F3N3O2
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
431.45
Ref: TM-T12054
| 1mg | 225.00 € | ||
| 5mg | 555.00 € | ||
| 10mg | 804.00 € | ||
| 25mg | 1,191.00 € | ||
| 50mg | 1,585.00 € | ||
| 100mg | 2,147.00 € | ||
| 200mg | 2,785.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
PF-184298
CAS:813447-40-4
PF-184298 is a serotonin and norepinephrine monoamine reuptake inhibitor (SNRI) that inhibits dopamine reuptake.
Formula:
C15H20Cl2N2O
Purity:
98.30%
Color and Shape:
Solid
Molecular weight:
315.24
Ref: TM-T28380
| 1mg | 276.00 € | ||
| 5mg | 680.00 € | ||
| 10mg | 930.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
Lesopitron
CAS:132449-46-8
Lesopitron: anxiolytic, 5-HT1A agonist, treats rodent anxiety, counters benzodiazepine withdrawal, low toxicity, no alcohol/barbiturate interaction.
Formula:
C15H21ClN6
Purity:
98.60% - 98.92%
Color and Shape:
Solid
Molecular weight:
320.82
Ref: TM-T25672
| 1mg | 138.00 € | ||
| 5mg | 337.00 € | ||
| 10mg | 495.00 € | ||
| 25mg | 797.00 € | ||
| 50mg | 1,096.00 € | ||
| 100mg | 1,477.00 € | ||
| 500mg | 2,960.00 € |
Estimated delivery in United States, on Tuesday 28 Jan 2025
PAF (C16)
CAS:74389-68-7
PAF, short for Platelet-activating factor, is a mediator of platelet aggregation and a ligand for …
Formula:
C26H54NO7P
Purity:
Min. 95%
Molecular weight:
523.68 g/mol
Ref: 3D-ZCA38968
| 1mg | 400.00 € | ||
| 2mg | 569.00 € | ||
| 5mg | 881.00 € | ||
| 10mg | 1,276.00 € | ||
| 25mg | 1,913.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Siponimod fumarate
CAS:1234627-85-0
Siponimod is a synthetic, polymorphic drug that has been developed to treat autoimmune and inflammatory …
Purity:
Min. 95%
Ref: 3D-BS168323
| 1g | 3,824.00 € | ||
| 50mg | 400.00 € | ||
| 100mg | 626.00 € | ||
| 250mg | 1,243.00 € | ||
| 500mg | 2,169.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Ubrogepant
CAS:1374248-77-7
Ubrogepant is a small-molecule drug that is used to treat migraine. It inhibits the activity …
Formula:
C29H26F3N5O3
Purity:
Min. 95%
Molecular weight:
549.54 g/mol
Ref: 3D-FU165699
| 1mg | 1,148.00 € | ||
| 2mg | 1,531.00 € | ||
| 5mg | 2,104.00 € | ||
| 10mg | 3,507.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
Phentolamine Analogue 1
CAS:47142-51-8
Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective antagonist of α-adrenergic.
Formula:
C17H19N3O
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
281.35
Ref: TM-T12444
| 1mg | 83.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
(Rac)-Modipafant
CAS:122956-68-7
(Rac)-Modipafantis a PAFR antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits.
Formula:
C34H29ClN6O3
Purity:
97.82% - 98.09%
Color and Shape:
Solid
Molecular weight:
605.09
Ref: TM-T28081
| 1mg | 205.00 € | ||
| 5mg | 511.00 € | ||
| 10mg | 739.00 € | ||
| 25mg | 1,138.00 € | ||
| 50mg | 2,250.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
Osemozotan HCl
CAS:137275-80-0
Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.
Formula:
C19H22ClNO5
Purity:
98.87% - 99.63%
Color and Shape:
Solid
Molecular weight:
379.84
Ref: TM-T28270
| 1mg | 350.00 € | ||
| 5mg | 837.00 € | ||
| 10mg | 1,144.00 € | ||
| 25mg | 1,688.00 € | ||
| 50mg | 2,287.00 € | ||
| 100mg | 3,061.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
RTI-13951-33
CAS:2244884-08-8
RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional …
Formula:
C28H33N3O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
459.58
Ref: TM-T12778L
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
BMS-960
CAS:1265321-86-5
BMS-960 is an S1P agonist with potential anti-tumour activity for cancer research.
Formula:
C26H23F3N4O5
Purity:
97.74% - 99.28%
Color and Shape:
Solid
Molecular weight:
528.48
Ref: TM-T26866
| 1mg | 705.00 € | ||
| 5mg | 1,467.00 € | ||
| 25mg | 2,661.00 € | ||
| 50mg | 3,978.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
LPA1 receptor antagonist 1
CAS:1396006-71-5
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a lysophosphatidic acid receptor antagonist for the …
Formula:
C28H26N4O4
Purity:
99% - 99.58%
Color and Shape:
Solid
Molecular weight:
482.53
Ref: TM-T15785
| 1mg | 142.00 € | ||
| 5mg | 341.00 € | ||
| 10mg | 545.00 € | ||
| 25mg | 853.00 € | ||
| 50mg | 1,141.00 € | ||
| 100mg | 1,549.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
GLP-1R agonist 3
CAS:2428640-18-8
GLP-1R agonist 3 is a GLP-1R agonist, an imidazole derivative.GLP-1R agonist 3 can be used …
Formula:
C31H28FN5O4
Purity:
97.19%
Color and Shape:
Liquid
Molecular weight:
553.58
Ref: TM-T63909
| 1mg | 126.00 € | ||
| 5mg | 292.00 € | ||
| 10mg | 479.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,548.00 € |
Estimated delivery in United States, on Tuesday 11 Feb 2025
4-Thiouridine 5′-triphosphate tetralithium
CAS:20188-72-1
4-Thiouridine 5′-triphosphate tetralithium (4-Thio-UTP), a potent P2Y2 and P2Y4 receptor agonist, exhibits EC50 values of …
Formula:
C9H11Li4N2O14P3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
523.94
Ref: TM-T79196
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 11 Feb 2025
