G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
Read more
Bosentan
CAS:147536-97-8
Bosentan is a competitive endothelin receptor antagonist, used for treating pulmonary arterial hypertension.
Formula:
C27H29N5O6S
Purity:
100% - 99.8%
Color and Shape:
Pale Yellow To Off-White Solid
Molecular weight:
551.614
Ref: TM-T6264
| 10mg | 38.00 € | ||
| 25mg | 55.00 € | ||
| 50mg | 80.00 € | ||
| 100mg | 124.00 € | ||
| 200mg | 202.00 € | ||
| 500mg | 304.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Cebranopadol
CAS:863513-91-1
Cebranopadol (GRT6005) is an analgesic NOP and opioid receptor agonist with Kis of 0.9 nM, …
Formula:
C24H27FN2O
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
378.48
Ref: TM-T5167
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 402.00 € | ||
| 200mg | 585.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Palosuran hydrochloride 540769-28-6(free base)
Palosuran hydrochloride 540769-28-6(free base)(ACT-058362 hydrochloride) is a new potent and specific antagonist of the human …
Formula:
C25H31ClN4O2
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
454.99
Ref: TM-T4689
| 1mg | 65.00 € | ||
| 2mg | 104.00 € | ||
| 5mg | 181.00 € | ||
| 10mg | 281.00 € | ||
| 25mg | 456.00 € | ||
| 50mg | 653.00 € | ||
| 1mL*10mM (DMSO) | 181.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
CAY10471 Racemate
CAS:844639-57-2
CAY10471 Racemate is a potent CRTH2/DP2 antagonist with Ki of 0.6 nM; less active on …
Formula:
C21H21FN2O4S
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
416.47
Ref: TM-T7359
| 5mg | 50.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 136.00 € | ||
| 50mg | 196.00 € | ||
| 100mg | 290.00 € | ||
| 200mg | 419.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
CJC-1295 acetate(863288-34-0 free base)
CJC-1295 acetate is a synthetic GHRH analogue and GHS.
Formula:
C154H256N44O44
Purity:
98%
Color and Shape:
Solid
Molecular weight:
3428.01
Ref: TM-TP2328L
| 1mg | 86.00 € | ||
| 5mg | 168.00 € | ||
| 10mg | 252.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 582.00 € | ||
| 100mg | 787.00 € | ||
| 200mg | 1,044.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
EST64454 hydrochloride
CAS:1950569-11-5
EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the …
Formula:
C18H23ClF2N4O2
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
400.85
Ref: TM-T8834
| 1mg | 51.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 318.00 € | ||
| 50mg | 515.00 € | ||
| 100mg | 817.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
CP 376395
CAS:175140-00-8
CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.
Formula:
C21H30N2O
Purity:
99.83% - 99.96%
Color and Shape:
Solid
Molecular weight:
326.48
Ref: TM-T4329
| 1mg | 41.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 133.00 € | ||
| 25mg | 262.00 € | ||
| 50mg | 416.00 € | ||
| 100mg | 661.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
ML-18
CAS:1422269-30-4
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.
Formula:
C32H35N5O5
Purity:
100% - 98.53%
Color and Shape:
Solid
Molecular weight:
569.65
Ref: TM-T4540
| 1mg | 35.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 173.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 434.00 € | ||
| 200mg | 598.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Protease-Activated Receptor-1, PAR-1 Agonist acetate
PAR-1 Agonist acetate is a selective PAR-1 agonist that mimics thrombin action.
Formula:
C37H62N10O11
Purity:
98.18%
Color and Shape:
Liquid
Molecular weight:
822.95
Ref: TM-T38836L
| 1mg | 130.00 € | ||
| 5mg | 251.00 € | ||
| 10mg | 363.00 € | ||
| 25mg | 609.00 € | ||
| 50mg | 866.00 € | ||
| 100mg | 1,182.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
PRE-084 hydrochloride
CAS:75136-54-8
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
Formula:
C19H28ClNO3
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
353.88
Ref: TM-T3198L
| 5mg | 44.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 204.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Dapagliflozin
CAS:461432-26-8
Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.
Formula:
C21H25ClO6
Purity:
99.5% - 99.74%
Color and Shape:
Solid
Molecular weight:
408.87
Ref: TM-T2389
| 5mg | 49.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 80.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 111.00 € | ||
| 200mg | 148.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Galanin (1-16), mouse, porcine, rat
CAS:125118-77-6
Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with …
Formula:
C78H116N20O21
Purity:
98.65%
Color and Shape:
White Powder
Molecular weight:
1669.88
Ref: TM-TP1380
| 1mg | 162.00 € | ||
| 5mg | 461.00 € | ||
| 10mg | 672.00 € | ||
| 25mg | 1,051.00 € | ||
| 50mg | 1,388.00 € | ||
| 100mg | 1,857.00 € | ||
| 500mg | 3,684.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Montelukast sodium
CAS:151767-02-1
Montelukast sodium (MK0476), an oral leukotriene antagonist for asthma, can cause rare liver injury.
Formula:
C35H35ClNNaO3S
Purity:
99.35% - 99.89%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
608.17
Ref: TM-T1677L
| 50mg | 53.00 € | ||
| 100mg | 76.00 € | ||
| 500mg | 132.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
MS21570
CAS:65373-29-7
MS21570 as a GPR171 antagonist based on its ability to block,with an IC50 of 220 …
Formula:
C10H11N3S2
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
237.34
Ref: TM-T5828
| 5mg | 45.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 146.00 € | ||
| 100mg | 211.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Dexmedetomidine
CAS:113775-47-6
Dexmedetomidine: a central alpha-2 adrenergic agonist for general anesthesia.
Formula:
C13H16N2
Purity:
100% - 99.96%
Color and Shape:
Solid
Molecular weight:
200.28
Ref: TM-T2524
| 25mg | 46.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 94.00 € | ||
| 200mg | 149.00 € | ||
| 500mg | 245.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
1-methoxycyclopropanecarboxylic acid
CAS:100683-08-7
1-methoxycyclopropanecarboxylic acid is an agonist of free fatty acid receptor 3 (FFAR3, human).
Formula:
C5H8O3
Purity:
99.44%
Color and Shape:
Light-Yellow To Yellow Solid Or Liquid
Molecular weight:
116.12
Ref: TM-T9437
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 110.00 € | ||
| 100mg | 164.00 € | ||
| 200mg | 238.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
SB-265610
CAS:211096-49-0
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.
Formula:
C14H9BrN6O
Purity:
97.67%
Color and Shape:
Solid
Molecular weight:
357.16
Ref: TM-T16850
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 370.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 786.00 € | ||
| 500mg | 1,612.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
VER-155008
CAS:1134156-31-2
VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and …
Formula:
C25H23Cl2N7O4
Purity:
98.88% - 99.55%
Color and Shape:
Solid
Molecular weight:
556.4
Ref: TM-T7010
| 2mg | 46.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 457.00 € | ||
| 200mg | 639.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Brimonidine Tartrate
CAS:70359-46-5
Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 …
Formula:
C15H16BrN5O6
Purity:
99.83%
Color and Shape:
Off-White Crystalline Solid
Molecular weight:
442.22
Ref: TM-T6422
| 100mg | 48.00 € | ||
| 500mg | 121.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
TC-O 9311
CAS:444932-31-4
TC-O 9311 (TCO-9311) is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 …
Formula:
C20H19N3O4
Purity:
99.24% - 99.84%
Color and Shape:
Solid
Molecular weight:
365.38
Ref: TM-T4626L
| 5mg | 49.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 200.00 € | ||
| 100mg | 326.00 € | ||
| 200mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
