G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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ML221
CAS:877636-42-5
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s …
Formula:
C17H11N3O6S
Purity:
97.74%
Color and Shape:
Solid
Molecular weight:
385.35
Ref: TM-T4390
| 1ml | 55.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 240.00 € | ||
| 100mg | 435.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Ki16425
CAS:355025-24-0
Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 …
Formula:
C23H23ClN2O5S
Purity:
97.60% - 97.78%
Color and Shape:
Solid
Molecular weight:
474.96
Ref: TM-T6108
| 1ml | 59.00 € | ||
| 2mg | 41.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 360.00 € | ||
| 100mg | 503.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
PU-H54
CAS:1454619-13-6
PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.
Formula:
C18H19N5S
Purity:
98.42%
Color and Shape:
Solid
Molecular weight:
337.44
Ref: TM-T8958
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 525.00 € | ||
| 200mg | 712.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
BAR502
CAS:1612191-86-2
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
Formula:
C25H44O3
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
392.62
Ref: TM-TQ0252
| 1mg | 68.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 598.00 € | ||
| 100mg | 813.00 € | ||
| 200mg | 1,089.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
CGS 21680 Hydrochloride
CAS:124431-80-7
CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in …
Formula:
C23H29N7O6·HCl
Purity:
96.74% - 98.81%
Color and Shape:
Solid
Molecular weight:
535.98
Ref: TM-T6441
| 1mg | 40.00 € | ||
| 1ml | 90.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | 593.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
VKGILS-NH2 Acetate
VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor …
Formula:
C30H58N8O9
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
674.83
Ref: TM-T21699L
| 1mg | 34.00 € | ||
| 1ml | 93.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 337.00 € | ||
| 200mg | 479.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Hydroxyzine dihydrochloride
CAS:2192-20-3
Hydroxyzine dihydrochloride treats allergies, pruritus, anxiety; causes drowsiness; also an antiemetic and sedative.
Formula:
C21H27ClN2O2·2HCl
Purity:
99.79% - 99.79%
Color and Shape:
Oil Powder
Molecular weight:
447.83
Ref: TM-T2200
| 1g | 51.00 € | ||
| 1ml | 45.00 € | ||
| 100mg | 34.00 € | ||
| 200mg | 34.00 € | ||
| 500mg | 41.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
![1-[(5-methylisoxazol-3-yl)methyl]piperazine](https://static.cymitquimica.com/products/TM/thumb/T8582.jpg)
1-[(5-methylisoxazol-3-yl)methyl]piperazine
CAS:173850-51-6
1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI)) is a P2Y12 inhibitor.
Formula:
C9H15N3O
Purity:
95%
Color and Shape:
Solid
Molecular weight:
181.23
Ref: TM-T8582
| 1mg | 85.00 € | ||
| 1ml | 141.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Orphanin FQ(1-11) acetate(178249-41-7 free base)
Nociceptin peptide fragment (1-11 aa), potent ORL1/KOR-3 agonist (Ki=55 nM), non-opioid, analgesic in mice.
Formula:
C51H79N15O16
Purity:
95.54%
Color and Shape:
Solid
Molecular weight:
1158.26
Ref: TM-TP1882L1
| 1mg | 156.00 € | ||
| 5mg | 341.00 € | ||
| 10mg | 508.00 € | ||
| 25mg | 824.00 € | ||
| 50mg | 1,105.00 € | ||
| 100mg | 1,523.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Conopressin S acetate(111317-90-9 free base)
Conopressin S acetate(111317-90-9 free base) (Con-S acetate) is a natural product isolated from Conus striatus, …
Formula:
C43H77N17O12S2
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
1088.32
Ref: TM-TP1192L
| 5mg | 54.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 190.00 € | ||
| 100mg | 285.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
![[Sar9,Met(O2)11]-Substance P](https://static.cymitquimica.com/products/TM/thumb/T7828.jpg)
[Sar9,Met(O2)11]-Substance P
CAS:110880-55-2
[Sar9,Met(O2)11]-Substance P (NA) is an agonist of NK1 receptor.
Formula:
C64H100N18O15S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
1393.66
Ref: TM-T7828
| 1mg | 83.00 € | ||
| 5mg | 267.00 € | ||
| 10mg | 480.00 € | ||
| 25mg | 783.00 € | ||
| 50mg | 1,084.00 € | ||
| 100mg | 1,457.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:960404-48-2
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal …
Formula:
C24H35ClO9
Purity:
99.39% - 99.94%
Color and Shape:
Solid
Molecular weight:
502.98
Ref: TM-T4460
| 1ml | 35.00 € | ||
| 10mg | 43.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 60.00 € | ||
| 100mg | 74.00 € | ||
| 500mg | 161.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Glucagon (19-29), human acetate
Glucagon (19-29), human acetate a COOH-terminal fragment processed from glucagon, is a potent and efficient …
Formula:
C63H93N15O20S
Purity:
98.11%
Color and Shape:
Solid
Molecular weight:
1412.57
Ref: TM-TP1863L
| 5mg | 64.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 353.00 € | ||
| 200mg | 523.00 € | ||
| 500mg | 789.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
3-AQC
CAS:201216-42-4
3-AQC is a competitive antagonist of 5-HT3.
Formula:
C20H21N5O4
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
395.41
Ref: TM-T8475
| 1ml | 55.00 € | ||
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 136.00 € | ||
| 100mg | 198.00 € | ||
| 200mg | 292.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
BMS986188
CAS:1776115-10-6
BMS986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor.
Formula:
C30H31BrO4
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
535.47
Ref: TM-T8992
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 284.00 € | ||
| 200mg | 397.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Clebopride malate
CAS:57645-91-7
Clebopride malate is a dopamine antagonist drug Used to treat functional gastrointestinal disorders such as …
Formula:
C24H30ClN3O7
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
507.96
Ref: TM-T7569
| 1ml | 37.00 € | ||
| 5mg | 35.00 € | ||
| 10mg | 46.00 € | ||
| 25mg | 68.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 141.00 € | ||
| 200mg | 203.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
A-381393
CAS:726174-00-1
A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for …
Formula:
C20H24N4
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
320.43
Ref: TM-T5397
| 1mg | 39.00 € | ||
| 1ml | 85.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 292.00 € | ||
| 100mg | 422.00 € | ||
| 200mg | 593.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
Empagliflozin
CAS:864070-44-0
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with …
Formula:
C23H27ClO7
Purity:
98% - 99.89%
Color and Shape:
Solid
Molecular weight:
450.91
Ref: TM-T1766
| 1g | 277.00 € | ||
| 1ml | 51.00 € | ||
| 5mg | 46.00 € | ||
| 10mg | 60.00 € | ||
| 50mg | 78.00 € | ||
| 100mg | 94.00 € | ||
| 200mg | 142.00 € | ||
| 500mg | 185.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
ABT-702 dihydrochloride
CAS:1188890-28-9
ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor.
Formula:
C22H21BrCl2N6O
Purity:
98.89% - 99%
Color and Shape:
Solid
Molecular weight:
536.25
Ref: TM-T4668
| 1mg | 61.00 € | ||
| 1ml | 140.00 € | ||
| 2mg | 85.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 343.00 € | ||
| 50mg | 520.00 € | ||
| 100mg | 732.00 € | ||
| 500mg | 1,542.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
AVN-101
CAS:1061354-48-0
AVN-101 is a very potent 5-HT7 receptor antagonist (Ki = 153 pM).
Formula:
C21H25ClN2
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
340.89
Ref: TM-T26690
| 1mg | 38.00 € | ||
| 1ml | 95.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 575.00 € |
Estimated delivery in United States, on Tuesday 15 Oct 2024
