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Complement System

Complement System

The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.

Found 168 products of "Complement System"

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  • Avdoralimab

    CAS:
    Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting complement C5a receptor 1 (C5aR1).
    Purity:>95%
    Color and Shape:Liquid
    Molecular weight:145.9 kDa

    Ref: TM-T76913

    1mg
    256.00€
    5mg
    762.00€
    10mg
    1,209.00€
    25mg
    1,737.00€
    50mg
    2,340.00€
  • Cyclosporin A

    CAS:
    Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.
    Formula:C62H111N11O12
    Purity:99.00% - 99.92%
    Color and Shape:White Powder
    Molecular weight:1202.61

    Ref: TM-T0945

    1g
    150.00€
    50mg
    40.00€
    100mg
    52.00€
    500mg
    97.00€
    1mL*10mM (DMSO)
    55.00€
  • SB290157 trifluoroacetate

    CAS:
    SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).
    Formula:C24H29F3N4O6
    Purity:98.93% - 99.89%
    Color and Shape:Solid
    Molecular weight:526.51

    Ref: TM-T12851

    5mg
    50.00€
    10mg
    81.00€
    25mg
    160.00€
    50mg
    264.00€
    100mg
    464.00€
    1mL*10mM (DMSO)
    66.00€
  • Ravulizumab

    CAS:
    Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:145.80 kDa

    Ref: TM-T76867

    1mg
    235.00€
    5mg
    588.00€
    10mg
    944.00€
    25mg
    1,396.00€
    50mg
    1,882.00€
    100mg
    2,547.00€
  • PMX 205 acetate(514814-49-4 free base)


    PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
    Formula:C47H66N10O8
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:899.09

    Ref: TM-T12506L1

    1mg
    105.00€
    5mg
    266.00€
    10mg
    350.00€
    25mg
    745.00€
    50mg
    1,189.00€
    100mg
    1,735.00€
    1mL*10mM (DMSO)
    374.00€
  • Dexamethasone

    CAS:
    Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.
    Formula:C22H29FO5
    Purity:98% - 99.91%
    Color and Shape:Crystals From Ether (Ntp 1992)
    Molecular weight:392.46

    Ref: TM-T1076

    50mg
    33.00€
    1mL*10mM (DMSO)
    50.00€
  • Tesidolumab

    CAS:
    Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.
    Purity:99.72% (SEC-HPLC) - > 95%
    Color and Shape:Liquid
    Molecular weight:142 kDa (average)

    Ref: TM-T76831

    1mg
    188.00€
    5mg
    472.00€
    10mg
    787.00€
    25mg
    1,169.00€
    50mg
    1,568.00€
    100mg
    2,118.00€
  • Compstatin TFA


    Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).
    Formula:C68H100F3N23O19S2
    Color and Shape:Solid
    Molecular weight:1664.79

    Ref: TM-T75775

    5mg
    To inquire
    50mg
    To inquire
  • PMX-53

    CAS:
    PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.
    Formula:C47H65N11O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:896.09

    Ref: TM-T28429

    1mg
    1,064.00€
  • Pegcetacoplan acetate


    Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.
    Color and Shape:Odour Solid

    Ref: TM-TP2795

    10mg
    To inquire
    50mg
    To inquire
  • ATWLPPR Peptide TFA


    ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.
    Formula:C42H62F3N11O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:954

    Ref: TM-T10408

    50mg
    To inquire
    100mg
    To inquire
  • 3-O-(2'E,4'Z-Decadienoyl)ingenol


    3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.
    Formula:C30H42O6
    Color and Shape:Solid
    Molecular weight:498.66

    Ref: TM-T124104

    1mg
    To inquire
    5mg
    To inquire
  • Claseprubart

    CAS:
    Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.
    Color and Shape:Liquid

    Ref: TM-T9901A-931

    1mg
    To inquire
    5mg
    To inquire
  • PIC1 PA TFA


    PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.
    Formula:C71H123N19O21S2·xC2HF3O2
    Color and Shape:Solid

    Ref: TM-TP3251

    10mg
    To inquire
    50mg
    To inquire
  • PMX 205 Trifluoroacetate


    PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.
    Formula:C47H63F3N10O8
    Color and Shape:Solid
    Molecular weight:953.06

    Ref: TM-T73710

    5mg
    To inquire
    50mg
    To inquire
  • Vemircopan

    CAS:
    Vemircopan is a complement factor D inhibitor.
    Formula:C29H28BrN7O3
    Color and Shape:Solid
    Molecular weight:602.493

    Ref: TM-T39493

    5mg
    783.00€
    10mg
    1,224.00€
  • TLQP-21

    CAS:
    TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.
    Formula:C107H170N40O26
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2432.75

    Ref: TM-TP2296

    1mg
    1,198.00€
  • ARC186


    ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.
    Color and Shape:Solid
    Molecular weight:120702.76

    Ref: TM-T75106

    5mg
    To inquire
    50mg
    To inquire
  • AMY-101

    CAS:
    AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.
    Formula:C83H117N23O18S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1789.11

    Ref: TM-TP2139

    100mg
    To inquire
    500mg
    To inquire
  • Factor B-IN-1

    CAS:
    Factor B-IN-1 is a Factor B inhibitor.
    Formula:C19H16N4O2
    Color and Shape:Solid
    Molecular weight:332.3559

    Ref: TM-T38969

    5mg
    612.00€