Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65580 products of "Quinazoline and Quinoline Derivatives"
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(Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid is a stereoisomer of Epalrestat (E565300), an aldose reductase inhibitor. Used in the treatment of diabetic neuropathy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Terashima, H., et al.: J. Pharmacol. Exp. Ther., 229, 226 (1983), Kikkawa, R., et al.: Diabetologia, 24, 290 (1983), Kojima, K., et al.: Jpn. J. Ophthalmol., 29, 99 (1985), Qi, M. et al.: J. Beij, Inst. Tech., 13, 445 (2004);<br></p>Formula:C15H13NO3S2Color and Shape:Yellow-Red SolidMolecular weight:319.4Deshydroxyethoxy Ticagrelor
CAS:<p>Applications Deshydroxyethoxy Ticagrelor analog of Ticagrelor (T437700) an antiplatelet agent, and preventative in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases.<br>References Zhang, H. et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>Formula:C21H24F2N6O3SColor and Shape:White To Off-WhiteMolecular weight:478.521-piperazine-1-yl-isoquinoline
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:213.28399658203125Desfluoro Risperidone
CAS:Controlled Product<p>Impurity Risperidone EP Impurity K<br>Applications Desfluoro Risperidone (Risperidone EP Impurity K) is a Risperidone (R525000) impurity, as antipsychotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C23H28N4O2Color and Shape:NeatMolecular weight:392.492-(1-Amino-2-methylpropyl)-3-benzyl-7-chloroquinazolin-4(3H)-one
CAS:Purity:98%Molecular weight:341.8399963378906N-Nitrosomorpholine-d8
CAS:Controlled Product<p>Applications N-Nitrosomorpholine-d8 (CAS# 1219805-76-1) is a useful isotopically labeled research compound.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C42H8N2O2Color and Shape:Light YellowMolecular weight:124.17Rivastigmine-d4 Tartrate Salt
CAS:Controlled Product<p>Applications Rivastigmine-d4 Tartrate Salt, is the labeled analogue of Rivastigmine Tartrate Salt (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C18H24D4N2O8Color and Shape:NeatMolecular weight:404.456-fluoro-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:259.299987792968755-(4'-Methyl-2-biphenyl)tetrazole
CAS:<p>Impurity Irbesartan EP Impurity E / Irbesartan Methyl Impurity/ Losartan Impurity E<br>Applications Valsartan (V095750) impurity.<br>References Thai, H., et al.: J. Cardiovasc. Pharmacol., 50, 703 (2007), Lukas, J., et al.: Science, 313, 662 (2006),<br></p>Formula:C14H12N4Color and Shape:NeatMolecular weight:236.277-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
CAS:Purity:98%Molecular weight:454.29901123046875Hydroxydehydro Nifedipine Carboxylate
CAS:Controlled ProductFormula:C16H14N2O7Color and Shape:NeatMolecular weight:346.29(E)-N-(4-(1-BENZOYLPIPERIDIN-4-YL)BUTYL)-3-(PYRIDIN-3-YL)ACRYLAMIDE
CAS:Purity:95.0%Molecular weight:391.51501464843752-Methyl-6-trifluoromethyl-nicotinic acid methyl ester
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:219.16299438476562Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid
CAS:Controlled Product<p>Applications Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid is a reactant used in the preparation of peptidase IV inhibitors.<br>References Park, W. et al.: Bioorg. Med. Chem. Lett., 21, 1366 (2011);<br></p>Formula:C15H18F3NO4Color and Shape:NeatMolecular weight:333.342-O-tert-Butyldimethylsilyloxyethyl Rapamycin
CAS:<p>Stability Hygroscopic<br>Applications 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin is a useful synthetic intermediate in the synthesis of Everolimus (E945400); an immunosuppressant macrolide and analog of the parent drug Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002); Venkata, S.P., et al.: PCT Int. Appl. WO 2012066502 A1 20120524. May 24, 2012<br></p>Formula:C59H97NO14SiColor and Shape:NeatMolecular weight:1072.48Ebastine
CAS:<p>Applications A nonsedating type histamine H1-receptor antagonist. Antihistaminic.<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Inomata, N., et al.: J. Dermatol., 36, 224 (2009), Carvajal, A., et al.: Clin. Pharmacol. Ther., 85, 481 (2009), Yamashita, S., et al.: Mol. Pharm., 6, 48 (2009),<br></p>Formula:C32H39NO2Color and Shape:White To Off-WhiteMolecular weight:469.66Mavoglurant
CAS:Controlled Product<p>Applications Mavoglurant is a non-competitive metabotropic glutamate receptor 5 (mGlu5) receptor antagonist.<br>References Vranesic, I., et al.; Bioorg. Med. Chem., 22, 5790 (2014); Kubas, H., et al.: Bioorg. Med. Chem. Lett., 23, 6370 (2013)<br></p>Formula:C19H23NO3Color and Shape:NeatMolecular weight:313.395-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole
CAS:Controlled Product<p>Applications Sitagliptin intermediate. An anti-hypertensive agent for the treatment of diabetes and hypertension.<br>References Sarges, R, et al.: J. Med. Chem., 33, 2240 (1990),<br></p>Formula:C4H2ClF3N2OColor and Shape:NeatMolecular weight:186.52Cinnarizine
CAS:<p>Applications Calcium channel blocker with antiallergic and anti-vasoconstricting activity. Antihistaminic.<br>References Barber, J.H., et al.: Pharmatherapeutica, 2, 401 (1980), Spedding, M., et al.: Arch. Pharmacol., 318, 234 (1982), Morad, et al.: Pharmacol. Res., 35, 177 (1997)<br></p>Formula:C26H28N2Color and Shape:NeatMolecular weight:368.51Decoquinate
CAS:Controlled Product<p>Applications Decoquinate is a quinolone coccidiostat used in veterinary medicine, in particular as animal feed for poultry.<br>References Del Cacho, E. et al.: Int. J. Parasitol., 36, 1515 (2006); Guo, F.C. et al.: Vet. Parasitol., 147, 239 (2007); Davis, J.L. et al.: Vet. Pharmacol. Therap., 9, 1145 (2009);<br></p>Formula:C24H35NO5Color and Shape:Off-WhiteMolecular weight:417.54Despiperazine Amino Norfloxacin
CAS:Controlled ProductFormula:C12H11FN2O3Color and Shape:NeatMolecular weight:250.22(S)-(-)-Carvedilol
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications The optically active isomer of Carvedilol (C184625), a nonselective ß-adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990),<br></p>Formula:C24H26N2O4Color and Shape:Off White SolidMolecular weight:406.474-methyl-2-(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)aniline
CAS:Purity:95.0%Molecular weight:252.27699279785156Bisnortilidine
CAS:Controlled Product<p>Applications A metabolite of Tilidine (T440300(M)), which is a controlled substance (opiate) and a analgesic. Tilidine is used in clinical trial in comparison with Nefopam. Tilidine is one of the most widely used narcotics in Germany and Belgium.<br>References Hengy, H., et al.: J. Pharm. Sci., 67, 1765 (1978); Cordonnier, J., et al.: J. Anal. Toxicol., 11, 144 (1987); Hajda, J., et al.: J. Clin. Pharmacol., 42, 1257 (2002); Vollmer, K.-O., et al.: Arzneim.-Forsch., 20, 990 (1970); Abeloos, J., et al.: Acta Anaesthesiol. Belg., 34, 283 (1983); Van Cauwenberge, H., et al.: Int. J. Clin. Pharmacol. Res., 12, 1 (1992)<br></p>Formula:C15H19NO2Color and Shape:NeatMolecular weight:245.322-Amino-4-(4-cyclohexyl-phenyl)-thiophene-3-carboxylic acid methyl ester
CAS:Formula:C18H21NO2SPurity:97%Color and Shape:SolidMolecular weight:315.432-[4-[2-(1-Piperidinyl)ethoxy]benzoyl]benzoic Acid
CAS:<p>Applications 2-[4-[2-(1-Piperidinyl)ethoxy]benzoyl]benzoic Acid is a research reagent with antispasmodic<br>References Bal-Tembe, S., et al.: Bioorg. Med. Chem., 5, 1381(1997);Punekar, N., et al.: Biotech. App. Biochem, 14, 378 (1991);<br></p>Formula:C21H23NO4Color and Shape:NeatMolecular weight:353.41Ondansetron
CAS:Controlled Product<p>Applications Ondansetron is a specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>Formula:C18H19N3OColor and Shape:White To Light BeigeMolecular weight:293.36N,O-Bis(trimethylsilyl)trifluoroacetamide (~90%)
CAS:Controlled Product<p>Applications Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Driscoll, J.S. et al.: J. Med. Chem., 34, 3280 (1991); Pan, L. et al.: J. Pharm. Biomed. Anal., 52, 589 (2010);<br></p>Formula:C8H18F3NOSi2Purity:~90%Color and Shape:Colourless To Light YellowMolecular weight:257.402-(4-Chlorophenoxy)aniline
CAS:Controlled Product<p>Applications Amoxapine impurity.<br>References Matsuo, M., et al.: Chem. Pharma. Bull., 33, 4409 (1985),<br></p>Formula:C12H10ClNOColor and Shape:NeatMolecular weight:219.674-Bromo Riluzole
CAS:Controlled Product<p>Applications 4-Bromo Riluzole is an impurity of Riluzole (R510000); a benzothiazole derivative that is used to treat amyotrophic lateral sclerosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ahamed, A., et al.: J. Pharm. Res., 3, 1028 (2010); Satyanarayana, B., et al.: ARKIVOC, no vol., 109 (2008)<br></p>Formula:C8H4BrF3N2OSColor and Shape:NeatMolecular weight:313.094-Ethoxy-3-(3-pyridin-2-yl-ureido)benzenesulfonyl chloride
CAS:Formula:C14H14ClN3O4SPurity:98%Color and Shape:SolidMolecular weight:355.79Dehydronitroso Nifedipine
CAS:Controlled Product<p>Impurity Nifedipine EP Impurity B<br>Applications A photodegradation product of Nifedipine (N457000). Shown to relax contractions of the rat aortic strip induced by norepinephrine and other agonists.<br>References Hayase, N. et at.: J. Pharmac. Exp. Ther., 275, 813 (1995); De Vries, H. et al.: Photochem. Photobio., 62, 959 (1995);<br></p>Formula:C17H16N2O5Color and Shape:NeatMolecular weight:328.32rac-Vigabatrin-13C,d2 (Major)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Vigabatrin. A novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.<br>References Vajda, F., et al.: Clin. Neurosci., 7, 88 (2000), Beghi, E., et al.: Lancet. Neurol., 3, 618 (2004), Sagirli, O., et al.: J. Pharmaceut. Biomed., 42, 618 (2006),<br></p>Formula:C513CH9D2NO2Color and Shape:White To Dark YellowMolecular weight:132.16L-Homoserine Lactone, Hydrochloride
CAS:Controlled Product<p>Applications L-Homoserine Lactone, Hydrochloride (cas# 2185-03-7) is a compound useful in organic synthesis.<br></p>Formula:C4H7NO2·ClHColor and Shape:NeatMolecular weight:137.56Vioxx-d5 (Major)
CAS:Controlled Product<p>Applications A selective labelled cyclooxygenase-2 (COX-2) inhibitor. Use as an anti-inflammatory, analgesic.<br>References Catalla-Lawson, F., et al.: J. Pharmacol. Exp. Ther., 289, 735 (1999), Ehrich, E.W., et al.: Clin. Pharmacol. Ther., 65, 336 (1999), Langman, M.J., et al.: J. Am. Med. Assoc., 282, 1929 (1999),<br></p>Formula:C172H5H9O4SColor and Shape:NeatMolecular weight:319.387Carvedilol N’-2-Hydroxy-3-[[2-(methoxyphenoxy)ethyl]amine
CAS:Controlled Product<p>Impurity Carvedilol Impurity A; Carvedilol USP A<br>Applications An impurity from the process of Carvedilol (C184625). Carvedilol impurity A. Carvedilol USP A.<br></p>Formula:C36H43N3O7Color and Shape:NeatMolecular weight:629.742-(CHLOROMETHYL)-4-(2,2,3,3,4,4,4-HEPTAFLUOROBUTOXY)PYRIDINE
CAS:Purity:95.0%Molecular weight:325.6099853515625rac Talinolol-d5
CAS:Controlled Product<p>Applications Labelled Talinolol. Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.<br>References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),<br></p>Formula:C202H5H28N3O3Color and Shape:Off White CrystallineMolecular weight:368.52Roflumilast-d4
CAS:Controlled Product<p>Applications Labelled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease.<br>References Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001), Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001), Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002), Rabe, K.F., et al.: Lancet, 366, 563 (2005),<br></p>Formula:C17D4H10Cl2F2N2O3Color and Shape:NeatMolecular weight:407.23N-Dehydroxyzileuton
CAS:Controlled Product<p>Applications N-Dehydroxyzileuton is a pharmacologically inactive metabolite of Zileuton (Z420000), an inhibitor of 5-lipoxygenase that is used to treat patients with asthma.<br>References Awni, W., et al.: Clin. Pharm., 29, 62 (1995); Machinist, J., et al.: Clin. Pharm., 29, 34 (1995); Remko, M., et al.: Phys. Chem. Chem. Phys., 2, 2511 (2000);<br></p>Formula:C11H12N2OSColor and Shape:NeatMolecular weight:220.29Desmethyl Ofloxacin-d8 Hydrochloride
CAS:Controlled Product<p>Applications A labelled metabolite of Ofloxacin.<br>References Leysen, D., et al.: Antimicrob. Agents Chemother., 33, 1 (1989), Polk, R., et al.: J. Antimicrob. Chemother., 27, 17 (1991), Todo, Y., et al.: Chem. Pharm. Bull., 42, 2049 (1994), Furuhata, K., et al.: Biol. Pharm. Bull., 21, 456 (1998)<br></p>Formula:C17H11D8ClFN3O4Color and Shape:NeatMolecular weight:391.851,3-Bis(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiourea
CAS:Purity:98%Molecular weight:448.54998779296875(S)-5-Iodo Naproxen
CAS:Controlled ProductFormula:C14H13IO3Color and Shape:NeatMolecular weight:356.163-Hydroxyagomelatine
CAS:<p>Impurity Agomelatine Impurity 11/ Agomelatine 3-Hydroxy Impurity<br>Applications 3-Hydroxyagomelatine is an intermediate in the synthesis of 1-(aminoethyl)naphthalene derivative with potential binding affinity for melatonin receptors. Agomelatine Impurity 11<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simonin, G., et al.: J. Pharma. Biomed. Anal., 21, 591 (1999)<br></p>Formula:C15H17NO3Color and Shape:NeatMolecular weight:259.32-[-2[(5-Nitro-2-furanyl)methylene]hydrazinyl]acetic Acid
CAS:Controlled Product<p>Applications 2-[-2[(5-Nitro-2-furanyl)methylene]hydrazinyl]acetic Acid is an impurity of Nitrofurantoin (N493850), a nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals.<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976); Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004);<br></p>Formula:C7H7N3O5Color and Shape:NeatMolecular weight:213.148Letermovir
CAS:<p>Applications Letermovir acts as an orally or i.v administered cytomegalovirus terminus complex inhibitor, antiviral agent, used in the treatment of CMV infection which is prevalent in those with immunocompromised systems.<br>References Kropeit, D. et al.: Brit. J. Clin Pharmacol., 83, 2678 (2017); Kim, E. et al.: Drugs. 78, 147 (2018);<br></p>Formula:C29H28F4N4O4Color and Shape:NeatMolecular weight:572.551Ref: 10-F340506
1gTo inquire5gTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquirePaliperidone Palmitate N-Oxide
CAS:Controlled Product<p>Applications Paliperidone Palmitate N-Oxide is a metabolite of Paliperidone Palmitate (P141020).<br></p>Formula:C39H57FN4O5Color and Shape:NeatMolecular weight:680.89(5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindoline-2,2’-dione)
CAS:<p>Impurity Ziprasidone EP Impurity D<br>Applications (5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindoline-2,2’-dione) (Ziprasidone EP Impurity D) is a compound related to Ziprasidone (Z485000), which is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Used as an antipsychotic.<br>References Bench, C.J., et al.: Psychopharmacology, 112, 308 (1993), Goldstein, J.M.: Exp. Opin. Invest. Drugs, 4, 291 (1995)<br></p>Formula:C42H40Cl2N8O3S2Color and Shape:NeatMolecular weight:839.85N4-(3-Chloro-4-fluorophenyl)-7-ethoxyquinazoline-4,6-diamine (Afatinib Impurity)
CAS:Purity:97%Molecular weight:332.76Carisoprodol
CAS:Controlled Product<p>Applications Muscle relaxant (skeletal).<br>References Musso, D., et al.: J. Med. Chem. 46, 399 (2003), Newman, P., et al.: Eur. J. Clin. Pharm., 23, 31 (1982).<br></p>Formula:C12H24N2O4Color and Shape:White To Off-WhiteMolecular weight:260.33Bromperidol
CAS:<p>Applications Bromine analog of Haloperidol. Antipsychotic.<br>References Niemegeers, C.J.E., et al.: Life Sci., 24, 2201 (1979), Van Den Eeckhout, E., et al.: Eur. J. Drug Metab. Pharmacokinet., 5, 45 (1980), Vincent, S.H., et al.: J. Med. Chem., 23, 75 (1980),<br></p>Formula:C21H23BrFNO2Color and Shape:NeatMolecular weight:420.32Empagliflozin α-Anomer
CAS:Controlled ProductFormula:C23H27ClO7Color and Shape:White To Off-WhiteMolecular weight:450.9093-acetyl-6-chloro-4-(4-fluorophenyl)quinolin-2(1H)-one
CAS:Purity:95.0%Molecular weight:315.7300109863281O-Desmethyl Everolimus (Technical Grade)
CAS:Controlled Product<p>Applications O-Desmethyl Everolimus is an impurity of Everolimus (E945400). Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Formula:C52H81NO14Color and Shape:NeatMolecular weight:944.22-[(1S,3R)-3-Hydroxycyclopentyl]-9-methoxy-1,8-dioxo-N-[(2,4,6-trifluorophenyl)methyl]pyrido[1,2-a]pyrazine-7-carboxamide
CAS:Formula:C22H20F3N3O5Color and Shape:Neat5-Fluoro Risperidone
CAS:Controlled Product<p>Impurity Risperidone EP Impurity D<br>Applications 5-Fluoro Risperidone (Risperidone EP Impurity D) is a Risperidone (R525000) impurity.<br></p>Formula:C23H27FN4O2Color and Shape:NeatMolecular weight:410.48(1R,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
CAS:Controlled Product<p>Applications An intermediate and impurity in the synthesis of Tadalafil (T004500).<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Formula:C20H18N2O4Color and Shape:NeatMolecular weight:350.37N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
CAS:Purity:95.0%Molecular weight:396.6700134277344Mirtazapine N-Glucuronide (Mixture of Diastereomers) Contains Unknown Inorganics >80%
CAS:Controlled Product<p>Applications Mirtazapine N-Glucuronide is a metabolite of Mirtazapine (M365000), an α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.<br>References Smith, D.A., RSC Drug Discovery Series, 1, 193 (2010); De Boer, T., et al.: Neuropharmacology, 27, 399 (1988); Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Formula:C23H28N3O6Purity:>80%Color and Shape:NeatMolecular weight:442.48Procymidox
CAS:Controlled Product<p>Applications Systemic agricultural fungicide.<br>References Ozer, N., et al.: J. Phytopathol., 158, 744 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),<br></p>Formula:C13H11Cl2NO2Color and Shape:Off WhiteMolecular weight:284.14N-Des-(2-chloroethyl) Chlorambucil
CAS:Controlled Product<p>Applications N-Des-(2-chloroethyl) Chlorambucil is the half-mustard analog of Chlorambucil (C325050) and exhibits mutagenic activity.<br>References Ferguson, L.R., et al.: Anti-Cancer Drug Des., 3, 67 (1988)<br></p>Formula:C12H16ClNO2Color and Shape:Off WhiteMolecular weight:241.7141,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
CAS:Controlled Product<p>Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);<br></p>Formula:C17H17N3OColor and Shape:White To Off-WhiteMolecular weight:279.343-(1-Pyridin-4-yl-3,4-dihydroisoquinolin-2(1H)-yl)propanoic acid
CAS:Purity:90.0%Molecular weight:282.3429870605469(S)-2-((tert-Butoxycarbonyl)amino)pentane-1,5-diyl Dimethanesulfonate
CAS:Controlled ProductFormula:C12H25NO8S2Color and Shape:NeatMolecular weight:375.459Empagliflozin (Tetrahydrofuranyl-d4)
CAS:Controlled Product<p>Applications Empagliflozin-d4 is a labelled analog of Empagliflozin (E521510); a novel, potent and selective SGLT-2 inhibitor, improves glycaemic control and features of metabolic syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C23D4H23ClO7Color and Shape:NeatMolecular weight:454.9343-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3
CAS:Controlled Product<p>Applications Intermediate in the preparation of labelled Nilotinib.<br>References Zhang, G., et al.: Bioorg. Med. Chem. Lett., 19, 6691 (2009), Seeliger, M., et al.: Cancer Res., 69, 2384 (2009),<br></p>Formula:C11H7D3F3N3Color and Shape:NeatMolecular weight:244.24Carvedilol Bis-carbazole
CAS:Controlled Product<p>Impurity Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B<br>Applications Carvedilol Bis-carbazole (Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B) is an impurity from the process of Carvedilol (C184625).<br></p>Formula:C39H39N3O6Color and Shape:Off-White To Light BeigeMolecular weight:645.74Ritonavir
CAS:<p>Applications A selective HIV protease inhibitor. It is a COVID19-related research product.<br>References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006)<br></p>Formula:C37H48N6O5S2Color and Shape:NeatMolecular weight:720.94Minoxidil-d10
CAS:Controlled Product<p>Applications Deuterated Minoxidil, which is used as an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Franz, T.J., Arch. Dermatol., 121, 203 (1985), Gadwood, R.C., et al.: Annu. Rep. Med. Chem., 24, 187 (1989), Hautala, T., et al.: Biochem. J., 283, 51 (1992)<br></p>Formula:C92H10H5N5OColor and Shape:White To Off-WhiteMolecular weight:219.31Deoxy Epinephrine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Andregenic and dopamine receptor agonist; active metabolite of Ibopramine (I123500). Also, it is used as internal standard in chromatographic analysis of catecholamines.<br>References Kindler, P., et al.: Arch. Pharm., 270, 340 (1932), Bridgers, W.F., et al.: J. Biol. Chem., 237, 526 (1962),<br></p>Formula:C9H13NO2·ClHColor and Shape:Light Brown To PurpleMolecular weight:203.67(R)-N-Desacryloyl N-Propionyl Ibrutinib
CAS:<p>Applications (R)-N-Desacryloyl N-Propionyl Ibrutinib is an inhibitor for bruton’s tyrosine kinase.<br>References Pan, Z., et al.: ChemMedChem (2007), 2(1), 58-61<br></p>Formula:C25H26N6O2Color and Shape:NeatMolecular weight:442.512-Amino-5-ethyl-thiophene-3-carboxylic acid methylester
CAS:Formula:C8H11NO2SPurity:95+%Color and Shape:SolidMolecular weight:185.24Tianeptine
CAS:<p>Applications Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.<br>References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991),<br></p>Formula:C21H25ClN2O4SColor and Shape:White To Off-WhiteMolecular weight:436.953-Cyclohexyl-6,8-dibromo-3-methyl-1,2,3,4-tetrahydroquinazolinium Chloride
CAS:<p>Impurity Bromhexine EP Impurity E Chloride<br>Applications 3-Cyclohexyl-6,8-dibromo-3-methyl-1,2,3,4-tetrahydroquinazolinium Chloride is an impurity of Bromhexine Hydrochloride (B678600). Bromhexine Hydrochloride impurity E Chloride. Bromhexine is an expectorant; mucolytic.<br>References Goicoechea, H., et al.: Talanta, 49, 793 (1999), Ribone, M., et al.: J. Pharm. Biomed. Anal., 23, 591 (2000),<br></p>Formula:C15H21Br2N2·ClColor and Shape:NeatMolecular weight:424.616-Methyl-5-((3-(2-(methylthio)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-amine
CAS:Purity:98%Molecular weight:374.4599914550781Carprofen Glucuronide
CAS:<p>Stability Hygroscopic<br>Applications Carprofen Glucuronide is a derivative of Carprofen (C184350), a non steroidal anti-inflammatory that is used by veterinarians for the relief of arthritic systems in dogs. It can be used for joint pain or post operative inflammation. Carprofen, is also used for the relief from pain and inflammation associated with osteoarthritis, hip dysplasia and other joint issues.<br>References Randall, L.O., et al.: Arch. Int. Pharmacodyn., 220, 94 (1976), Yu, T.F., et al.: J. Clin. Pharmacol., 20, 347 (1980), O’Brien, W.M., et al.: Pharmacotherapy, 7, 16 (1987),<br></p>Formula:C21H20ClNO8Color and Shape:Light BrownMolecular weight:449.84
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