Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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Everolimus-d4 (>85%)
CAS:Controlled Product<p>Applications Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Formula:C532H4H79NO14Purity:>85%Color and Shape:White To Light YellowMolecular weight:962.25(R)-Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity D<br>Applications (R)-Rivastigmine (Rivastigmine EP Impurity D) is a carbamate inhibitor of acetylcholinesterase used as a treatment of Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lucangioli, S. E., et al.: J. Chromatogr. A, 1081, 31-35 (2005); Bar-On, P., et al.: Biochem., 41, 3555-3564 (2002);<br></p>Formula:C14H22N2O2·C4H6O6Color and Shape:NeatMolecular weight:400.422-Methoxy-5-(morpholine-4-sulfonyl)-benzoic acid
CAS:Formula:C12H15NO6SColor and Shape:SolidMolecular weight:301.31(2S,2'S)-1,1'-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)imino]bis(1-oxo-2,1-ethanediyl)]bis-2-pyrrolidinecarbonitrile
CAS:Formula:C24H33N5O3Color and Shape:Off-WhiteMolecular weight:439.55Safinamide Mesylate
CAS:Controlled Product<p>Applications Safinamide mesylate is a potent and selective MAO-B inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C17H19FN2O2·CH4O3SColor and Shape:White To Off-WhiteMolecular weight:398.45Telmisartan-d3
CAS:Controlled ProductFormula:C332H3H27N4O2Color and Shape:BeigeMolecular weight:517.646-fluoro-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:259.299987792968754,5-dimethyl-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.3699951171875GLPG-0634 (Filgotinib)
CAS:Controlled Product<p>Applications GLPG-0634 (Filgotinib) is a potent, selective JAK1 inhibitor. Used as an anti-inflammatory agent, it reduces levels of inflammatory cytokines in the bones and tissue of mammals.<br>References Moran, N. et al.: BioWorld Int., 16, 1 (2011);<br></p>Formula:C21H23N5O3SColor and Shape:NeatMolecular weight:425.52,3-Dihydroxypropyl 2-((7-chloroquinolin-4-yl)amino)benzoate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:372.80999755859375Dasatinib monohydrate
CAS:Controlled ProductFormula:C22H26ClN7O2S·H2OColor and Shape:White To Off-WhiteMolecular weight:506.02Brexpiprazole-d8
CAS:Controlled Product<p>Applications Isotope labelled Brexpiprazole (B677385) is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders.<br>References Yamashita, H., et al.: PCT Int. Appl., WO 2006112464 A1 20061026 (2006)<br></p>Formula:C25H19D8N3O2SColor and Shape:White To BeigeMolecular weight:441.621-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl-7-hydroxy-3,4-dihydro Carbostyril (Aripiprazole Imp
CAS:<p>Applications This compound is an impurity in the synthesis of Aripiprazole (A771000) which is a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Formula:C23H27Cl2N3O2Color and Shape:NeatMolecular weight:448.39o-Flutamide
CAS:Controlled Product<p>Impurity Flumazenil EP Impurity F<br>Applications o-Flutamide is an isomer of Flutamide (F598850), a nonsteroidal antiandrogen drug; antineoplastic (hormonal).<br>References Neri, et al.: Endocrinology, 91, 427 (1972), Sogani, P.C., et al.: J. Urol., 122, 640 (1979), Greenway, B.A., et al.: Br. Med. J., 316, 1935 (1998),<br></p>Formula:C11H11F3N2O3Color and Shape:NeatMolecular weight:276.213-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>Applications 3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a byproduct in the synthesis of 5-Fluoro Paliperidone (F595170), which is a Paliperidone (P141000) impurity.<br></p>Formula:C11H11ClN2O2Color and Shape:Yellow To GreenMolecular weight:238.67Clofazimine-d7
CAS:Controlled Product<p>Applications Labelled Clofazimine (C324300). Antibacterial (tuberculostatic, leprostatic).<br>References Doak, A., et al.: J. Med. Chem., 53, 4259 (2010), Rodgers, A., et al.: Chem. Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Formula:C27H15D7Cl2N4Color and Shape:NeatMolecular weight:480.445-p-Tolyl-1H-pyrazole-3-carboxylic acid methyl ester
CAS:Purity:95.0%Molecular weight:216.240005493164068-Hydroxy Amoxapine
CAS:<p>Applications A metabolite of Amoxapine.<br>References Hansen, E., et al.: Drug Metab. Dispos.,15, 97 (1987), Hansen, E., et al.: Xenobiotica, 25, 1081 (1995), Moody, J., et al.: Drug Metab. Dispos., 27, 1157 (1999),<br></p>Formula:C17H16ClN3O2·ClHColor and Shape:NeatMolecular weight:366.242-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid
CAS:Purity:97%Molecular weight:313.739990234375Nilotinib Regio Isomer
CAS:Controlled Product<p>Applications Nilotinib Regio Isomer is a more potent Bcr-Abl tyrosine kinase inhibitor for the treatment of patients with myelogenous leukemia. It is a COVID19-related research product.<br>References Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Bilbe, G.,et al.: From PCT Int. Appl. (2005), WO 2005039586 A1 20050506<br></p>Formula:C28H22F3N7OColor and Shape:NeatMolecular weight:529.52(2R,3S)-rel-Nadolol-de(N-tert-butyl)methoxy
<p>Impurity Nadolol EP Impurity B<br>Stability Hygroscopic<br>Applications (2R,3S)-rel-Nadolol-de(N-tert-butyl)methoxy is an impurity of Nadolol (N201050), a β-Adrenergic blocker. Antihypertensive; antianginal.<br>References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977); Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978); Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980)<br></p>Formula:C14H20O5Color and Shape:NeatMolecular weight:268.304-AMINO-1-[2,3-O-(1-METHYLETHYLIDENE)PENTOFURANOSYL]-1,3,5-TRIAZIN-2(1H)-ONE
CAS:Purity:95.0%Molecular weight:284.2720031738281N-Methyl-3,3-diphenylpropylamine
CAS:<p>Applications N-Methyl-3,3-diphenylpropylamine is an intermediate for the synthesis of SNRI-NMDA antagonist and neuroprotectants.<br>References Olney, J. et al.: Sci., 244, 1360 (1989); Williams, W., et al.: Mol. Pharmacol. 44, 851 (1993);<br></p>Formula:C16H19NColor and Shape:NeatMolecular weight:225.33Haloperidol-d4
CAS:Controlled Product<p>Applications Antidyskinetic; antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Janicki, C.A., et al.: Anal. Profiles Drug Subs., 9, 341 (1980), Beresford, R., et al.: Drugs, 33, 31 (1987)<br></p>Formula:C212H4H19ClFNO2Color and Shape:WhiteMolecular weight:379.89Hydantoin
CAS:Controlled Product<p>Applications Hydantoin (cas# 461-72-3) is a compound useful in organic synthesis.<br></p>Formula:C3H4N2O2Color and Shape:NeatMolecular weight:100.08Linagliptin Acetamide
CAS:Controlled Product<p>Impurity Linagliptin N-Acetyl Impurity<br>Applications Linagliptin Acetamide is an impurity of linagliptin (L465900), which is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formula:C27H30N8O3Color and Shape:NeatMolecular weight:514.584-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride
CAS:Controlled ProductFormula:C14H17N3O4·ClHColor and Shape:NeatMolecular weight:327.762-(3-PYRIDINYLMETHYLENE)-1H-INDENE-1,3(2H)-DIONE
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:235.242004394531251,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one
CAS:Controlled Product<p>Impurity Ondansetron EP Impurity D; Ondansetron USP Related Compound D<br>Applications 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one (Ondansetron EP Impurity D; Ondansetron USP Related Compound D) is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011); Zizkovsky, V. et al.: J. Pharm. Biomed. Anal., 44, 1048 (2007)<br></p>Formula:C14H13NOColor and Shape:WhiteMolecular weight:211.26D-(+)-Epinephrine
CAS:<p>Applications D-(+)-Epinephrine, is an isomer of L-(-)-Epinephrine (E588580), is a hormone and a neurotransmitter. It is a Principal sympathomimetic hormone produced by the adrenal medulla. a Bronchodilator, cardiostimulant, mydriatic, and antiglaucoma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Malmejac, et al.: Physiol. Rev., 44, 186 (1964), Pohorecky, L.A., et al.: Pharmacol. Rev., 23, (1971), Hebert, P., et al.: J. Emerg. Med., 9, 487 (1991), McLean-Tooke, et al.: Br. Med. J., 327, 1332 (2003),<br></p>Formula:C9H13NO3Color and Shape:Off-White To Light BrownMolecular weight:183.20rac Ramelteon-d3
CAS:Controlled Product<p>Applications Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic.<br>References Yukuhiro, N., et al.: Brain Res., 59, 1027 (2004), Cajochen, C., et al.: Curr. Opin. Invest. Drugs, 6, 114 (2005), Kato, K., et al.: Neuropharmacology, 48, 301 (2005),<br></p>Formula:C16H18D3NO2Color and Shape:NeatMolecular weight:262.361?-Hydroxy Bufuralol-d9 (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity.<br>References Boobis, A.R., et al.: Biochem. Pharmacol., 34, 65 (1985), Yamazaki, H., et al.: Mol. Pharmacol., 46, 568 (1994), Mast, N., et al.: Biochem., 42, 14284 (2003),<br></p>Formula:C16H14D9NO3Color and Shape:White To YellowMolecular weight:286.41N-Benzyl Carvedilol
CAS:Controlled Product<p>Impurity Carvedilol EP Impurity C; Carvedilol Impurity C; Carvedilol USP C<br>Applications N-Benzyl Carvedilol (Carvedilol EP Impurity C) is an impurity of Carvedilol (C184625) and a degradation product in Carvedilol tablets.<br>References Karle, C., et al.: Cardiovasc. Res., 49, 361 (2001), Chen, J., et al.: Acta Cardiol. Sin., 19, 93 (2003), Xiang, T., et al.: Pharm. Res., 22, 1205 (2005),<br></p>Formula:C31H32N2O4Color and Shape:NeatMolecular weight:496.60Methyl-(1-methyl-1H-pyrazol-3-ylmethyl)-amine
CAS:Purity:95.0%Color and Shape:Liquid, liquidMolecular weight:125.17500305175781Propylthiouracil
CAS:Controlled Product<p>Applications Antihyperthyroid. Has been used to promote fattening. This substance is reasonably anticipated to be a human carcinogen.<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 6, 457 (1977), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984),<br></p>Formula:C7H10N2OSColor and Shape:White To Off-WhiteMolecular weight:170.231,2,3,4-Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol
CAS:Controlled ProductFormula:C18H21NO4Color and Shape:NeatMolecular weight:315.361-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid
CAS:Formula:C25H24N4O5Color and Shape:Light Orange ColourMolecular weight:460.484-[4-(4-Chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-1-(4-fluorophenyl)-1-butanone
CAS:<p>Applications 4-[4-(4-Chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-1-(4-fluorophenyl)-1-butanone is a dehydrated metabolite of haloperidol that can be biotransfomed by humans to Haloperidol pyridinium (HPP+), a potential neurotoxic found in the brain.<br>References Usuki, E., et. al.: Neurotoxicity Res., 4, 51 (2002)<br></p>Formula:C21H21ClFNOColor and Shape:NeatMolecular weight:357.85ETHYL 2-(3-METHYL-4-OXO-3,4-DIHYDROPHTHALAZIN-1-YL)ACETATE
CAS:Purity:95.0%Molecular weight:246.26600646972656(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride
CAS:Controlled ProductFormula:C12H17NO2·ClHColor and Shape:NeatMolecular weight:243.736-Chloro-pyrimidine-2,4-diamine
CAS:Controlled Product<p>Impurity Minoxidil EP Impurity B<br>Applications 6-Chloro-pyrimidine-2,4-diamine (cas# 156-83-2) is a compound useful in organic synthesis.<br></p>Formula:C4H5ClN4Color and Shape:WhiteMolecular weight:144.56Azobenzene
CAS:<p>Applications Impurity in the production of Phenylbutazone (P319570). Dyes and metabolites.<br>References Chung, K., et al.: Mutation Res., 114, 269 (1983), Kawanishi, S., et al.: J. Biol. Chem., 261, 5952 (1986), Floyd, R., et al.: Carcinogenesis, 11, 1447 (1990), Shibutani, S., et al.: Nature, 349, 431 (1991),<br></p>Formula:C12H10N2Color and Shape:NeatMolecular weight:182.22Saxagliptin Hydrate
CAS:Controlled Product<p>Applications Saxagliptin Hydrate is a selective and reversible dipeptidyl peptidase-4 (DPP4) inhibitor that may be used to develop treatment for type 2 diabetes.<br>References Gu, S., et al.: PLoS One. 11, e0167190 (2016); Dave, D. J.: J Pharmacol Pharmacother 2, 230 (2011)<br></p>Formula:C18H25N3O2·H2OColor and Shape:NeatMolecular weight:333.43Gefitinib Morpholine N-oxide
CAS:Controlled Product<p>Applications Gefitinib Morpholine N-oxide is the N-oxide derivative of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).<br>References Lynch, T.J., et al.: N. Engl. J. Med., 350, 2129 (2004); Engelman, J.A., et al.: Science, 316, 1039 (2007); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003)<br></p>Formula:C22H24ClFN4O4Color and Shape:White To Off-WhiteMolecular weight:462.902-(3-Pyridyl)-2-oxazoline
CAS:Controlled Product<p>Applications 2-(3-Pyridyl)-2-oxazoline is an impurity of Nicorandil (N398500). Nicorandil impurity E.<br></p>Formula:C8H8N2OColor and Shape:Off-White To Light YellowMolecular weight:148.16N-Benzyl Salbutamon Hydrochloride
CAS:Controlled Product<p>Applications N-Benzyl Salbutamon Hydrochloride is an impurity of Albuterol (Salbutamol) (A514500), an β2-adrenoceptor agonist. Bronchodilator; tocolytic.<br>References 1. Collin, D. et al.: J. Med. Chem. 1970 Jul;13(4):674-80.2. Raidal, S. et al.: Vet. J. 2017 Apr;222:22-28.<br></p>Formula:C20H25NO3·ClHColor and Shape:NeatMolecular weight:363.882-Acetoxy-N-(2-thiazolyl)benzamide
CAS:Controlled Product<p>Applications 2-Acetoxy-N-(2-thiazolyl)-benzamide is used in the synthesis of thiazolides as novel antiviral agents. Used in the inhibition of hepatitis C virus replication. Nitazoxanide Impurity<br>References Edwards, G. et al.: J. Med. Chem., 54, 8670 (2011);<br></p>Formula:C12H10N2O3SColor and Shape:Off-WhiteMolecular weight:262.287-Despropyl 7-Methyl Vardenafil
Controlled Product<p>Applications 7-Despropyl 7-Methyl Vardenafil is an impurity of Vardenafil (V098001, 2HCl); a selective phosphodiesterase type 5 (PDE5) inhibitor.<br>References Bischoff, E., et al.: J. Urol., 165, 1316 (2001); Kim, N.N., et al.: Life Sci., 69, 2249 (2001); Kendirci, M., et al.: Expert Opin. Pharmacother., 5, 923 (2004)<br></p>Formula:C21H28N6O4SColor and Shape:Off White SolidMolecular weight:460.55Vildagliptin-d3
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Vildagliptin. It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C17H22D3N3O2Color and Shape:NeatMolecular weight:306.42Salsalate-d8
CAS:Controlled Product<p>Applications Isotope labelled Nonacetylated aspirin analog. Analgesic, anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, L.L., et al.: J. Pharm. Sci., 69, 1268 (1980), Dromgoole, S.M., et al.: J. Pharm. Sci., 73, 1657 (1984),<br></p>Formula:C14H2D8O5Color and Shape:NeatMolecular weight:266.28(+/-)-4-Hydroxy Mephenytoin
CAS:Controlled Product<p>Applications CYP2C19 metabolite of Mephenytoin.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980)<br></p>Formula:C12H14N2O3Color and Shape:White SolidMolecular weight:234.253-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Controlled Product<p>Impurity Paliperidone USP Related Compound C<br>Applications Paliperidone USP Related Compound C<br></p>Formula:C11H15ClN2O2Color and Shape:Light Yellow To BrownMolecular weight:242.702-Descarboxy-2-cyano Telmisartan
CAS:<p>Impurity Telmisartan EP Impurity G<br>Applications 2-Descarboxy-2-cyano Telmisartan (Telmisartan EP Impurity G) is an impurity of the angiotensin II receptor antagonist, Telmisartan (T017000).<br>References Reddy, M.R. et al.: Int. J. Pharm. Pharmac. Sci., 4, 497 (2012);<br></p>Formula:C33H29N5Color and Shape:NeatMolecular weight:495.62L-Valine Methyl Ester Hydrochloride
CAS:Controlled Product<p>Applications L-Valine Methyl Ester Hydrochloride is used in the synthesis of Valaciclovir (V085000), the L-Valine ester prodrug of Acyclovir (A192400), orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.<br>References McClean, K. et al.: Tetrahedron Lett., 52, 215 (2011); Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992), Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),<br></p>Formula:C6H13NO2·ClHColor and Shape:NeatMolecular weight:167.63Argatroban Ethyl Ester
Controlled ProductFormula:C25H40N6O5SColor and Shape:NeatMolecular weight:536.6871-(2-Methoxyphenyl)piperazine
CAS:Controlled Product<p>Applications A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Byrska, B. et al.: Zagadnien Nauk Sadowych 81, 101 (2010); Cervo, L. et al.: Pharmacol Biochem Be 82, 727 (2005)<br></p>Formula:C11H16N2OColor and Shape:NeatMolecular weight:192.261-[3-(Trifluoromethyl)pyrid-2-yl]piperazine
CAS:Formula:C10H12F3N3Purity:98%Color and Shape:Solid, Low Melting SolidMolecular weight:231.222rac-Monepantel
CAS:Controlled Product<p>Applications rac-Monepantel is a recently discovered anthelmitic used in the treatment of parasitic nematodes via stun or kill without damaging the host entity.<br>References Baur, R. et al.: Mol. Pharm., 87, 96 (2015); Stuchlikova, L. et al.: Chemico. Biol. Interact., 227, 63 (2015);<br></p>Formula:C20H13F6N3O2SColor and Shape:Off White SolidMolecular weight:473.394-Diphenylmethoxypiperidine hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 4-Diphenylmethoxypiperidine, HCl<br></p>Formula:C18H21NO·ClHColor and Shape:WhiteMolecular weight:303.83γ-Aminobutyric Acid
CAS:<p>Applications An important inhibitory neurotransmitter. The foods contain γ-aminobutyric acid (GABA) at an amount that shows immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity.<br>References Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951), Gerlach, M., et al.: Brain Res., 741, 142 (1996), Choi, D., et al.: J Neurobiol 1992, 23, 1261<br></p>Formula:C4H9NO2Color and Shape:NeatMolecular weight:103.12Ilaprazole
CAS:Controlled Product<p>Applications Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.<br>References Cao, S., et al.: Acta Pharmacol. Sin., 33, 1095 (2012); Wang, L., et al.: J. Clin. Gastroenterol., 45, 322 (2011)<br></p>Formula:C19H18N4O2SColor and Shape:NeatMolecular weight:366.44Piperonylic Acid
CAS:Controlled Product<p>Applications Piperonylic Acid is a compound closely mimicking the structure of transcinnamic acid involved in the phenylpropanoid pathway in plant physiology.<br>References Schalk, M. et al.: Plant Physiol., 118, 209 (1998);<br></p>Formula:C8H6O4Color and Shape:NeatMolecular weight:166.133-(4-Chloro-5-methyl-pyrazol-1-yl)-propionic acid
CAS:Formula:C7H9ClN2O2Purity:95.0%Molecular weight:188.61Axitinib Tetrahydro-2H-pyran
CAS:Controlled ProductFormula:C27H26N4O2SColor and Shape:NeatMolecular weight:470.5862-Oxo-6-thiophen-2-yl-4-trifluoromethyl-1,2-dihydropyridine-3-carbonitrile
CAS:Formula:C11H5F3N2OSPurity:97%Color and Shape:SolidMolecular weight:270.23(+/-)-Epinephrine Hydrochloride
CAS:Controlled Product<p>Applications (+/-)-Epinephrine hydrochloride is an adrenergic receptor agonist; Neurotransmitter; Causes suppression of efferent activity of the adrenal nerve.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirano, T., et al.: J. Auton. Nerv. Syst., 1, 283-290 (1980)<br></p>Formula:C9H13NO3·ClHColor and Shape:Off-WhiteMolecular weight:219.67Meloxicam-d3
CAS:Controlled Product<p>Applications Labelled form of Meloxicam. Preferential cyclooxygenase (COX-2) inhibitor. Used as an anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hawkey, C., et al.: Br. J. Rheumatol., 35, Suppl. 1, 1 (1996), Fleischmann, R., et al.: Expert Opin. Pharmacother., 3, 1501 (2002),<br></p>Formula:C142H3H10N3O4S2Color and Shape:Light Yellow To YellowMolecular weight:354.42Desisopropyl Atrazine-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Atrazine (ATR) (A794600).<br>References Compton, D., et al.: Eur. J. Pharmacol., 110, 157 (1985), Das, P., et al.: Toxicol. Sci., 59, 127 (2001), Das, P., et al.: Life Sci., 73, 3123 (2003), Coban, A., et al.: J. Neurochem., 100, 1177 (2007),<br></p>Formula:C52H5H3ClN5Color and Shape:Off-WhiteMolecular weight:178.63Asenapine N-Oxide
CAS:Controlled Product<p>Applications A metabolite of Asenapine (A788000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ven der Wildenberg, H.M., et al.: Arzneim.-Forsch., 40, 540 (1990),<br></p>Formula:C17H16ClNO2Color and Shape:NeatMolecular weight:301.77ETHYL 1-METHYL-3-(4-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOLE-5-CARBOXYLATE
CAS:Purity:97.0%Molecular weight:298.2650146484375Reserpine-d9
CAS:Controlled Product<p>Applications Labelled Reserpine (R144600). An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.<br>References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),<br></p>Formula:C332H9H31N2O9Color and Shape:NeatMolecular weight:617.73Irbesartan
CAS:Controlled Product<p>Applications An angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997), Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998), Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008), Ren, X., et al.: Pharmacol., 83, 80 (2009),<br></p>Formula:C25H28N6OColor and Shape:NeatMolecular weight:428.53N,O-Dibenzoyl-L-tyrosine (>90%)
CAS:Controlled Product<p>Applications N,O-Dibenzoyl-L-tyrosine is an impurity of Tiropramide (T446900). Tiropramide impurity A.<br>References Fox, S.W., et al.: Arch. Biochem., 25, 13 (1950),<br></p>Formula:C23H19NO5Purity:>90%Color and Shape:White To Off-WhiteMolecular weight:389.42,3-Dihydro-3,5-dihydroxy-6-methyl-4-pyrone
CAS:Controlled ProductFormula:C6H8O4Color and Shape:NeatMolecular weight:144.13Dehydro Levetiracetam
CAS:<p>Impurity Levetiracetam EP Impurity B<br>Stability Light Sensitive<br>Applications Dehydro Levetiracetam (Levetiracetam EP Impurity B) is an impurity of Levetiracetam (L331500) which is an (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant.<br>References Gower, A. J., et al.: Eur. J. Pharmacol., 222, 193 (1992); Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996); Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000)<br></p>Formula:C8H12N2O2Color and Shape:WhiteMolecular weight:168.194-Amino-6-ethoxy-5-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]azo]-α-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]-2-pyrimidineacetonitrile
CAS:<p>Applications 4-Amino-6-ethoxy-5-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]azo]-α-[[4-[(4R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]-2-pyrimidineacetonitrile is a levosimendan dimer impurity, which is a bioactive enantiomer of racemate, Simendan. Positive inotropic agent with vasodilating activity. Cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995), Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996),<br></p>Formula:C30H30N12O3Color and Shape:NeatMolecular weight:606.642-(5-Methyl-3-nitropyrazol-1-yl)ethanol
CAS:Formula:C6H9N3O3Purity:95.0%Color and Shape:SolidMolecular weight:171.1567-Hydroxy-N-des{[2-(2-hydroxy)ethoxy]ethyl} Quetiapine Dihydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Quetiapine.<br>References McConville, B., et al.: J. Clin. Psychiatry, 61, 252 (2000), Wong, Y., et al.: J. Clin. Psychopharmacol, 21, 89 (2001), Cooper, K., et al.: Eur. J. Clin. Pharmacol., 59, 51 (2003),<br></p>Formula:C17H17N3OS·2ClHColor and Shape:White To Off-WhiteMolecular weight:384.32Carvedilol b-D-Glucuronide (mixture of diasteromers)
CAS:Controlled Product<p>Applications A metabolite of Carvedilol (C184625).<br>References McGurk, K., et al.: Biochem. Pharmacol., 55, 1005 (1998), Tukey, R., et al.: Annu. Rev. Pharmacol. Toxicol., 40, 581 (2000), Bowalgaha, K., et al.: Br. J. Clin. Pharmacol., 52, 605 (2001), Richardson, T., et al.: Drug Metab. Dispos., 34, 351 (2006),<br></p>Formula:C30H34N2O10Color and Shape:NeatMolecular weight:582.60Flubendazole
CAS:<p>Applications An anthelmintic.<br>References Thienpont, D., et al.: Arzneimittel-Forsch., 28, 605 (1978), Vanparijs, O., et al.: Vet. Parasitol, 5, 237 (1979),<br></p>Formula:C16H12FN3O3Color and Shape:ColourlessMolecular weight:313.28
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