Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65644 products of "Quinazoline and Quinoline Derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Tenoxicam
CAS:Controlled Product<p>Applications Nonsteroidal anti-inflamatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bird, H.A., et al.: Curr. Med. Res. Opin., 8, 9 (1982), Gonzalez, J.P., et al.: Drugs, 34, 289 (1987), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs. Excip., 22, 431 (1993),<br></p>Formula:C13H11N3O4S2Color and Shape:NeatMolecular weight:337.37[2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol
CAS:Controlled Product<p>Applications [2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol is used in the preparation of azepine.<br>References Lypacewicz, Maria K. et al., Pol.(1998);<br></p>Formula:C18H22N2OColor and Shape:White To Light BeigeMolecular weight:282.382-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine, Hydrochloride
CAS:Controlled ProductFormula:C9H9ClF3NO·ClHColor and Shape:NeatMolecular weight:276.081-(3-Hydroxypropyl)theobromine
CAS:Controlled ProductFormula:C10H14N4O3Color and Shape:White To Off-WhiteMolecular weight:238.243Nimodipine-d7
CAS:Controlled Product<p>Applications A labelled dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral).<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Formula:C21H19D7N2O7Color and Shape:NeatMolecular weight:425.48[2-(2-Methyl-1H-indol-3-yl)ethyl](pyridin-3-ylmethyl)amine dihydrochloride
CAS:Purity:95.0%Molecular weight:338.2799987792969Deacetyl Ketoconazole
CAS:Controlled Product<p>Impurity Ketoconazole EP Impurity D<br>Applications Deacetyl Ketoconazole (Ketoconazole EP Impurity D) is a Ketoconazole derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C24H26Cl2N4O3Color and Shape:Off-WhiteMolecular weight:489.39Oxaprozin
CAS:Controlled Product<p>Applications Oxaprozin is an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).<br>References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971), Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978), Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977),<br></p>Formula:C18H15NO3Color and Shape:NeatMolecular weight:293.321-Methoxy Empagliflozin
CAS:Controlled Product<p>Applications 1-Methoxy Empagliflozin is an impurity in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C24H29ClO8Color and Shape:White To Off-WhiteMolecular weight:480.945-(1,3-Dioxolan-2-yl)-2-(3-methoxybenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:290.32998657226567-Despropyl 7-Methyl Vardenafil
Controlled Product<p>Applications 7-Despropyl 7-Methyl Vardenafil is an impurity of Vardenafil (V098001, 2HCl); a selective phosphodiesterase type 5 (PDE5) inhibitor.<br>References Bischoff, E., et al.: J. Urol., 165, 1316 (2001); Kim, N.N., et al.: Life Sci., 69, 2249 (2001); Kendirci, M., et al.: Expert Opin. Pharmacother., 5, 923 (2004)<br></p>Formula:C21H28N6O4SColor and Shape:Off White SolidMolecular weight:460.55Vildagliptin-d3
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Vildagliptin. It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C17H22D3N3O2Color and Shape:NeatMolecular weight:306.42Salsalate-d8
CAS:Controlled Product<p>Applications Isotope labelled Nonacetylated aspirin analog. Analgesic, anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, L.L., et al.: J. Pharm. Sci., 69, 1268 (1980), Dromgoole, S.M., et al.: J. Pharm. Sci., 73, 1657 (1984),<br></p>Formula:C14H2D8O5Color and Shape:NeatMolecular weight:266.28(+/-)-4-Hydroxy Mephenytoin
CAS:Controlled Product<p>Applications CYP2C19 metabolite of Mephenytoin.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980)<br></p>Formula:C12H14N2O3Color and Shape:White SolidMolecular weight:234.253-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Controlled Product<p>Impurity Paliperidone USP Related Compound C<br>Applications Paliperidone USP Related Compound C<br></p>Formula:C11H15ClN2O2Color and Shape:Light Yellow To BrownMolecular weight:242.704-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol
CAS:Controlled Product<p>Applications 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Asaki, T., et al.: Bioorg. Med. Chem., 15, 6692 (2007); Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Formula:C23H27N3OColor and Shape:NeatMolecular weight:361.482-Mercapto-N-methyl-benzamide
CAS:Controlled Product<p>Stability Air Sensitive<br>Applications 2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),<br></p>Formula:C8H9NOSColor and Shape:BeigeMolecular weight:167.2283-Hydroxy Loratadine
CAS:Controlled Product<p>Applications An intermediate for the preparation of 3-Hydroxy Desloratadine.<br></p>Formula:C22H23ClN2O3Color and Shape:NeatMolecular weight:398.882-(4-Methyl-1H-pyrazol-1-yl)ethanol
CAS:Formula:C6H10N2OPurity:95.0%Color and Shape:LiquidMolecular weight:126.159(2,6-Dichloro-phenyl)guanidine
CAS:Controlled ProductFormula:C7H7Cl2N3Color and Shape:NeatMolecular weight:204.057(1S,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
CAS:Controlled Product<p>Applications An intermediate in the synthesis of thephosphodiesterase 5 inhibitor Tadalafil (T004500).<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Formula:C20H18N2O4Color and Shape:White To YellowMolecular weight:350.374-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
CAS:Controlled Product<p>Applications Sitagliptin intermediate.<br>References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),<br></p>Formula:C16H12F6N4O2Color and Shape:NeatMolecular weight:406.28Nitrofurantoin-13C3
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A nitrofuran labelled antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),<br></p>Formula:C3C5H6N4O5Color and Shape:NeatMolecular weight:241.14Nevirapine-d4 (cyclopropyl-2,2,3,3-d4)
CAS:Controlled Product<p>Applications Nevirapine-d4 (cyclopropyl-2,2,3,3-d4) (CAS# 1051418-95-1) is a useful isotopically labeled research compound. This can be prepared to use as non-nucleoside reverse transcriptase inhibitors.<br>References Gant, T., et.al., PCT Int.Appl., 113,(2008);<br></p>Formula:C15D4H10N4OColor and Shape:NeatMolecular weight:270.33Apixaban-d3
CAS:Controlled Product<p>Applications Apixaban-d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C25H22D3N5O4Color and Shape:White To Off-WhiteMolecular weight:462.524-Desmethyl-2-methyl Celecoxib
CAS:Controlled Product<p>Applications 4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib (C251000). It is a cyclooxygenase 2 inhibitor.<br>References Penning, T., et al.: J. Med. Chem., 40, 1347 (1997); Wesolowski, S., et al.: Bioorg. Med. Chem. Lett., 12, 267 (2002)<br></p>Formula:C17H14F3N3O2SColor and Shape:White To BeigeMolecular weight:381.37Ticagrelor Sulfoxide (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Ticagrelor Sulfoxide is an impurity of ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Formula:C23H28F2N6O5SColor and Shape:NeatMolecular weight:538.572-Phenylbutyric Acid
CAS:Controlled ProductFormula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.2Cabergoline N-Oxide
Controlled Product<p>Applications The N-oxide of Cabergoline (C050000), a dopamine D2-receptor agonist.<br>References Brambilla, E., et al.: Eur. J. Med. Chem., 24, 421 (1989), Ferrari, C., et al.: J. Clin. Endocrinol. Metab., 68, 1201 (1989), Hutton, J.T., et al.: Neurology, 46, 1062 (1996)<br></p>Formula:C26H37N5O3Color and Shape:NeatMolecular weight:467.6Saquinavir Mesylate
CAS:Controlled Product<p>Applications A selective HIV protease inhibitor. Antiviral.<br>References Roberts, N.A., et al.: Science, 248, 358 (1990), Craig, J.C., et al.: Antiviral Res., 16, 295 (1991),<br></p>Formula:C38H50N6O5·CH4O3SColor and Shape:NeatMolecular weight:766.95N-Nitroso Lisinopril
CAS:Formula:C21H30N4O6Color and Shape:White To Light YellowMolecular weight:434.486N,N-Dimethyl-4-hydroxymethoxy Clomiphene (~90%, contains ~10% Z-isomer)
CAS:Controlled ProductFormula:C25H26ClNO3Color and Shape:NeatMolecular weight:423.93Mitotane
CAS:Controlled Product<p>Applications An Antineoplastic. Used as an adrenolytic agent.<br>References Das, S., and Thomas, P.: Endocrinology, 140, 1953 (1999), Andersen, A., et al.: Ther. Drug. Monit., 21, 355 (1999), Leblond, V.S., and Hontela, T.: Toxicol. Appl. Pharmacol., 157, 16 (1999)<br></p>Formula:C14H10Cl4Color and Shape:White To Off-WhiteMolecular weight:320.04Nor Mianserin-d6 (Major)
Controlled Product<p>Applications Nor Mianserin-d6 (Major), is a labeled analogue of Nor Mianserin (N736800), an active metabolites of Miansein (M341500) in plasma, an antidepressant.<br>References Kent, J., et al.: Lancet, 355, 911 (2000), Maurer, H., et al.: Ther. Drug Monit., 24, 117 (2002),<br></p>Formula:C17H14D6N2Color and Shape:NeatMolecular weight:258.39Silodosin
CAS:<p>Applications Silodosin is an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertrophy.<br>References (1) Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995) (2) Murata, S., et al.: J. Urol., 164, 578 (2000)<br></p>Formula:C25H32F3N3O4Color and Shape:NeatMolecular weight:495.53Nadolol
CAS:Controlled Product<p>Applications β-Adrenergic blocker. Antihypertensive; antianginal.<br>References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977), Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978), Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980),<br></p>Formula:C17H27NO4Color and Shape:NeatMolecular weight:309.40Sodium Borohydride
CAS:<p>Applications Sodium Borohydride is used as a reagent in the reduction of amino acids and their derivatives. Also used in the catalysis of ammonia borane dehydrogenation.<br> E0<br>References McKennon, M. et al.: J. Org. Chem., 58, 3568 (1993); Denney, M. et al.: J. Am. Chem. Soc., 128, 12048 (2006);<br></p>Formula:BH4NaColor and Shape:White To Off-WhiteMolecular weight:37.8311-(4-Ethyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine Dihydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 11-(4-Ethyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine is an impurity of Quetiapine hemifumarate (Q510000), a dibenzothiazepine antipsychotic medication used in the treatment of schizophrenia.<br>References Kumar, K., et al.: Org. Chem.: An Indian Journal, 8, 164 (2012); Raju, I., et al.: Chromatographia, 70, 545 (2009)<br></p>Formula:C19H23Cl2N3SColor and Shape:NeatMolecular weight:396.38Nicorandil-d4
CAS:Controlled Product<p>Stability Unstable in Solution<br>Applications An antianginal.<br>References Yoneyama, F., et al.: Cardiovasc. Drugs Ther., 4, 1119 (1990), Purcell, H., et al.: Brit. J. Clin. Pract., 47, 150 (1993)<br></p>Formula:C82H4H5N3O4Color and Shape:NeatMolecular weight:215.20A77 1726 (E/Z) Mixture
CAS:Controlled Product<p>Impurity Leflunomide USP Related Compound B<br>Applications rac A77 1726 is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzyme’s teriflunomide therapy against relapsing forms of multiple sclerosis found the once-daily oral drug to be no less effective than injectable interferon beta 1a (Rebif®). Leflunomide USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>Formula:C12H9F3N2O2Color and Shape:NeatMolecular weight:270.212-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzamide
CAS:Purity:95.0%Molecular weight:297.28900146484375N-Ethyl-N-(4-picolyl)atropamide (>85%)
CAS:<p>Stability Light Sensitive<br>Applications N-Ethyl-N-(4-picolyl)atropamide is a major impurity of Tropicamide (T892650), a medication used to dilate the pupil.<br>References Stefanowicz, Zdzislawa, et al.: J. of Pharma. and Biomed. Analy., 49(2), 214-220 (2009)<br></p>Formula:C17H18N2OPurity:>85%Color and Shape:NeatMolecular weight:266.342-Keto Crizotinib
CAS:Controlled Product<p>Applications 2-Keto Crizotinib is an impurity of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C21H20Cl2FN5O2Color and Shape:NeatMolecular weight:464.32(1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester
CAS:Controlled Product<p>Applications An intermediate in the preparation of cis-Tadalafil (T004520). A PDE5 inhibitor.<br>References Beghyn, T. et al.: Bioorg. Med. Chem. Lett., 17, 789 (2007); Daugan, A. et al.: J. Med. Chem., 46, 4533 (2003);<br></p>Formula:C22H19ClN2O5Color and Shape:Off White SolidMolecular weight:426.85(R)-Lansoprazole
CAS:<p>Stability Hygroscopic<br>Applications The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColor and Shape:Off White To Dark BrownMolecular weight:369.362-[[2-2(2-Amino-4-thiazolyl)acetyl]amino]-4-thiazoleacetic Acid
CAS:Controlled ProductFormula:C10H10N4O3S2Color and Shape:NeatMolecular weight:114.142α,α,α',5-Tetramethyl-1,3-benzenediacetonitrile
CAS:Controlled ProductFormula:C14H16N2Color and Shape:NeatMolecular weight:212.29Rivaroxaban
CAS:<p>Applications A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C19H18ClN3O5SColor and Shape:White To BeigeMolecular weight:435.88rac-4-Hydroxy Propranolol Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications rac-4-Hydroxy Propranolol Hydrochloride is a metabolite of Propranolol.<br>References Walle, T., et al.: Drug Metab. Dispos., 13, 204 (1985), Mason, R., et al.: J. Med. Chem., 34, 869 (1991), Anderson, R., et al.: Biochem. Pharmacol., 52, 341 (1996), Hung, D., et al.: J. Pharmacol. Exp. Ther., 297, 780 (2001),<br></p>Formula:C16H21NO3·ClHColor and Shape:NeatMolecular weight:311.80Desmethyl 2N-Nitroso Mirtazapine-d6 (major)
Controlled ProductFormula:C16D6H10N4OColor and Shape:Neat4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
CAS:<p>Applications 4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C19H17Cl2N3O5SColor and Shape:NeatMolecular weight:470.331-(9H-Carbazol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
CAS:Controlled ProductFormula:C18H22N2O2Color and Shape:Colourless Crystalline PowderMolecular weight:298.382-Methyl-2-propyl-1,3-propanediol
CAS:Controlled Product<p>Applications An intermediate in the synthesis of Carisoprodol.<br></p>Formula:C7H16O2Color and Shape:NeatMolecular weight:132.20N-Nitroso Desmethyl Rizatriptan
Controlled ProductFormula:C14H16N6OColor and Shape:NeatMolecular weight:284.316Risperidone Z-Oxime Impurity
CAS:Controlled Product<p>Impurity Risperidone EP Impurity B<br>Applications Risperidone Z-Oxime (Risperidone EP Impurity B) is an impurity of Risperidone (R525000). Risperidone impurity per USP.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Formula:C23H28F2N4O2Color and Shape:NeatMolecular weight:430.493,5-Dichloro-4-(difluoromethyl)pyridine
CAS:Formula:C6H3Cl2F2NPurity:95.0%Color and Shape:LiquidMolecular weight:197.994’-(Trifluoromethyl)valerophenone-(E)-O-2-(2-aminoethyl) Oxime Maleate
Controlled Product<p>Applications 4’-(Trifluoromethyl)valerophenone(E)-O-2-(2-aminoethyl) Oxime Maleate is an impurity in the synthesis of Fluvoxamine (F603500), a selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant. Antiobsessional.<br>References Claassen, V., et al.: Br. J. Pharmacol., 60, 505 (1977), Koran, L.M., et al.: J. Clin. Psychopharmacol., 16, 121 (1996), Ware, M.R., et al.: J. Clin. Psychiatry, 58, Suppl. 5, 15 (1997), Inazu, M., et al.: Neurochem. Int., 39, 39 (2001)<br></p>Formula:C20H28F3N3O5Color and Shape:NeatMolecular weight:447.455,10-Dihydro-2-methyl-4H-thieno[2,3-b][1,5]benzodiazepin-4-one (Olanzapine Impurity)
CAS:<p>Impurity Olanzapine EP Impurity B/ Olanzapeine USP Related Compound B<br>Applications Olanzapine impurity (Olanzapine EP Impurity B).<br>References Fenselau, C., et al.: Xenobiotica, 22, 1207 (1992), Moore, N., et al.: J. Pharmacol. Exper. Ther., 262, 545 (1992), Kassahun, K., et al.: Drug Metab. Dispos., 25, 81 (1997),<br></p>Formula:C12H10N2OSColor and Shape:NeatMolecular weight:230.29N-Ethyl-N-methyl-3-vinylphenyl Carbamate
CAS:Controlled Product<p>Impurity Rivastigmine USP Related Compound F<br>Stability Light Sensitive<br>Applications A related compound of Rivastigmine (R541000), a cholinesterase inhibitor. Rivastigmine USP Related Compound F.<br></p>Formula:C12H15NO2Color and Shape:White SolidMolecular weight:205.25Eltrombopag Olamine
CAS:<p>Stability Hygroscopic<br>Applications Eltrombopag is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008)<br></p>Formula:C25H22N4O4·2C2H7NOColor and Shape:Dark RedMolecular weight:564.633,4-Dihydro-7-(4-hydroxybutoxy)-2(1H)-quinolinone
CAS:Formula:C13H17NO3Color and Shape:NeatMolecular weight:235.28Anastrozole
CAS:Controlled Product<p>Applications An aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formula:C17H19N5Color and Shape:NeatMolecular weight:293.37Uvinul A Plus
CAS:<p>Applications Uvinul A Plus is a component of cosmetic emulsion with UV protection.<br>References Chang, M., et al.: J. Food Drug Anal., 9, 199 (2001), Simeoni, S., et al.: J. Pharm. Biomed. Anal., 38, 250 (2005), Vielhaber, G., et al.: Photochem. Photobiol. Sci., 5, 275 (2006), Lee, S., et al.: J. Cosmet. Sci., 59, 469 (2008),<br></p>Formula:C24H31NO4Color and Shape:White To YellowMolecular weight:397.51Amido Methyl Meloxicam (Meloxicam Impurity)
CAS:Controlled Product<p>Applications Amido Methyl Meloxicam is an impurity of Meloxicam (M216100).<br>References Lazer, E., et al.: J. Med. Chem., 40, 980 (1997),<br></p>Formula:C15H15N3O4S2Color and Shape:NeatMolecular weight:365.43(±)-Bifonazole
CAS:<p>Applications (±)-Bifonazole acts as an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Formula:C22H18N2Color and Shape:NeatMolecular weight:310.393’-Anhydro Ezetimibe
CAS:Controlled ProductFormula:C24H19F2NO2Color and Shape:NeatMolecular weight:391.41(S)-Naproxen Ethyl Ester
CAS:<p>Impurity Naproxen EP Impurity F<br>Applications Naproxen (N377520) ethyl derivative. Naproxen impurity.<br>References Haddock, R., et al.: Xenobiotica, 14, 327 (1984), Jeremy, J., et al.: Drugs, 40, 53 (1990), Wadhwa, L., et al.: Int. J. Pharm., 118, 31 (1995),<br></p>Formula:C16H18O3Color and Shape:NeatMolecular weight:258.31(S)-O-Desmethyl Naproxen
CAS:Controlled Product<p>Applications A metabolite of Naproxen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rettie, A., et al.: Chem. Res. Toxicol., 5, 54 (1992), Tracy, T., et al.: Biochem. Pharmacol., 52, 1305 (1996), Bonnabry, P., et al.: Eur. J. Clin. Pharmacol., 49, 305 (1996), Rao, S., et al.: J. Med. Chem., 43, 2789 (2000), Hutzler, J., et al.: Drug Metab. Dispos., 29, 1029 (2001),<br></p>Formula:C13H12O3Color and Shape:WhiteMolecular weight:216.23Des(methoxycarbonyl) Febantel
CAS:Controlled Product<p>Applications Febantel (F227000) impurity. Anthelmintic.<br>References Wollweber, H., et al.: Arzneim.-Forsch., 34, 531 (1984),<br></p>Formula:C18H20N4O4SColor and Shape:NeatMolecular weight:388.44Asenapine N-β-D-Glucuronide Trifluoroacetic Acid Salt (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Asenapine N-β-D-Glucuronide is a metabolite of Asenapine (A788000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C23H25ClNO7·C2F3O2Color and Shape:NeatMolecular weight:575.92N1-Ethylcarbamoyl Cabergoline (>90%)
CAS:Formula:C29H42N6O3Color and Shape:Off White SolidMolecular weight:522.68Baricitinib
CAS:Controlled Product<p>Applications Baricitinib is a JAK1 and JAK2 inhibitor and have been used as a promising treatment for rheumatoid arthritis.<br>References Greenwald, L.J., et al.: Int. J. Clin. Rheumatol., 6, 401 (2011); Fridman, J.S., et al.: J. Immunol., 184, 5298 (2010);<br></p>Formula:C16H17N7O2SColor and Shape:White SolidMolecular weight:371.42N-Methyl β-Hydroxyl Phentermine
CAS:<p>Applications N-Methyl β-Hydroxyl Phentermine is derived from 2-Nitropropane (N519600), which is an oxidative stress-inducing agent and also a carcinogen. It is used in the induction of DNA polymerase β-dependent base excision repair in response to oxidative stress in the liver.<br>References Cabelof, D.C., et al.: Carcinogenesis,23, 1419 (2002); Kreis, P., et al.: Carcinogenesis, 21, 295 (2000)<br></p>Formula:C11H17NOColor and Shape:Off-WhiteMolecular weight:179.26rac-Epinephrine-3-O-sulfate
CAS:Formula:C9H13NO6SColor and Shape:White To Off-WhiteMolecular weight:263.2683-[4-(2-Methoxyphenyl)piperazin-1-yl]propan-1-amine
CAS:Controlled Product<p>Applications 3-[4-(2-methoxyphenyl)piperazin-1-yl]propan-1-amine (cas# 20529-23-1) is a useful research chemical.<br></p>Formula:C14H23N3OColor and Shape:NeatMolecular weight:249.35Rebamipide 3-Chloro Impurity (>80%)
CAS:Controlled Product<p>Applications Rebamipide 3-Chloro Impurity (CAS# 90098-05-8) is a useful research chemical compound.<br></p>Formula:C19H15ClN2O4Purity:>80%Color and Shape:White To Off-WhiteMolecular weight:370.7864Desmethyl Ofloxacin-d8 Hydrochloride
CAS:Controlled Product<p>Applications A labelled metabolite of Ofloxacin.<br>References Leysen, D., et al.: Antimicrob. Agents Chemother., 33, 1 (1989), Polk, R., et al.: J. Antimicrob. Chemother., 27, 17 (1991), Todo, Y., et al.: Chem. Pharm. Bull., 42, 2049 (1994), Furuhata, K., et al.: Biol. Pharm. Bull., 21, 456 (1998)<br></p>Formula:C17H11D8ClFN3O4Color and Shape:NeatMolecular weight:391.85(5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindoline-2,2’-dione)
CAS:<p>Impurity Ziprasidone EP Impurity D<br>Applications (5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindoline-2,2’-dione) (Ziprasidone EP Impurity D) is a compound related to Ziprasidone (Z485000), which is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Used as an antipsychotic.<br>References Bench, C.J., et al.: Psychopharmacology, 112, 308 (1993), Goldstein, J.M.: Exp. Opin. Invest. Drugs, 4, 291 (1995)<br></p>Formula:C42H40Cl2N8O3S2Color and Shape:NeatMolecular weight:839.85Carboxymefloquine-d3
CAS:Controlled Product<p>Applications Labelled Carboxymefloquine (C178700). Carboxymefloquine is a metabolite of Mefloquine (M207050).<br>References Crevoisier, C., et al.: Eur. J. Clin. Pharmacol., 53, 135 (1997), Ridtitid, W., et al.: J. Pharm. Pharmacol., 52, 1265 (2000),<br></p>Formula:C12H2D3F6NO2Color and Shape:NeatMolecular weight:312.18N-Nitroso Desmethyl Olopatadine
Controlled ProductFormula:C20H20N2O4Color and Shape:NeatMolecular weight:352.384N,N'-Methylene Ambroxol Hydrochloride
CAS:Controlled Product<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Formula:C14H18Br2N2O·ClHColor and Shape:White To Off-WhiteMolecular weight:426.57Chlorpromazine-d6 Oxalate (N,N-dimethyl-d6)
CAS:Controlled Product<p>Applications Chlorpromazine-d6 Oxalate (N,N-dimethyl-d6) (CAS# 1276197-23-9) is a useful isotopically labeled research compound.<br></p>Formula:C17D6H13ClN2S·C2H2O4Color and Shape:Off-WhiteMolecular weight:414.93N-Benzyl Hydroxymedetomidine
CAS:Controlled Product<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Formula:C20H22N2OColor and Shape:NeatMolecular weight:306.42-(Descyclohexylcarbonyl)-2-benzoyl Praziquantel
CAS:Controlled Product<p>Impurity Praziquantel USP Related Compound A<br>Applications 2-(Descyclohexylcarbonyl)-2-benzoyl Praziquantel is used in the synthesis of Praziquantel (P702095), anthelmintic, effective against flatworms. Praziquantel USP Related Compound A<br>References Liu, H. et al.: Chem. Biol. Drug Des., 79, 470 (2012);<br></p>Formula:C19H18N2O2Color and Shape:NeatMolecular weight:306.361-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS:<p>Applications Used in the preparation of Mirtazapine (M365000) impurities.<br></p>Formula:C17H18N4Color and Shape:Light Yellow To BrownMolecular weight:278.35
![[2-(4-Methyl-2-phenylpiperazin-1-yl)phenyl]methanol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM563455.webp&w=3840&q=75)
amine dihydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF494718.webp&w=3840&q=75)
![3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC366270.webp&w=3840&q=75)
![4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD491708.webp&w=3840&q=75)
![(1S,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM330155.webp&w=3840&q=75)
![4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluor…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FO864950.webp&w=3840&q=75)
![11-(4-Ethyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine Dihydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FE925790.webp&w=3840&q=75)
![(1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB121700.webp&w=3840&q=75)
![2-[[2-2(2-Amino-4-thiazolyl)acetyl]amino]-4-thiazoleacetic Acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA630535.webp&w=3840&q=75)
![4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiopheneca…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD435588.webp&w=3840&q=75)
![5,10-Dihydro-2-methyl-4H-thieno[2,3-b][1,5]benzodiazepin-4-one (Olanzapine Impurity)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD449185.webp&w=3840&q=75)
![3-[4-(2-Methoxyphenyl)piperazin-1-yl]propan-1-amine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM229390.webp&w=3840&q=75)
![(5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindol…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB203570.webp&w=3840&q=75)
