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Quinazoline and Quinoline Derivatives

Quinazoline and Quinoline Derivatives

Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules. At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.

Found 65562 products of "Quinazoline and Quinoline Derivatives"

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  • Tafamidis

    CAS:
    <p>Tafamidis stabilizes TTR, preventing amyloid buildup; binds with negative cooperativity (Kd1: 3 nM, Kd2: 278 nM); treats familial amyloid polyneuropathy.</p>
    Formula:C14H7Cl2NO3
    Purity:99.34% - 99.65%
    Color and Shape:Solid
    Molecular weight:308.12
  • Brexpiprazole Impurity 57


    Formula:C13H14ClNO2
    Molecular weight:251.71

    Ref: 4Z-B-115062

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  • Terazosin

    CAS:
    <p>Terazosin: oral α1-blocker, relaxes blood vessels, treats BPH and hypertension.</p>
    Formula:C19H25N5O4
    Color and Shape:Solid
    Molecular weight:387.43
  • Betahistine dihydrochloride

    CAS:
    <p>Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator.</p>
    Formula:C8H14Cl2N2
    Purity:99.34% - 99.88%
    Color and Shape:White To Light Yellow Crystalline Powder
    Molecular weight:209.12
  • (S)-Afatinib

    CAS:
    <p>(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.</p>
    Formula:C24H25ClFN5O3
    Purity:99.22% - >99.99%
    Color and Shape:Off-White Solid
    Molecular weight:485.94
  • Elenbecestat free base

    CAS:
    <p>Elenbecestat (E2609) is a BACE1 inhibitor that reduces Aβ peptide formation, potentially preventing amyloid plaques in the brain.</p>
    Formula:C19H15F6N5O2S
    Color and Shape:Solid
    Molecular weight:491.41
  • Mozavaptan

    CAS:
    <p>Mozavaptan (OPC-31260) is a competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.</p>
    Formula:C27H29N3O2
    Purity:98.98% - 99.12%
    Color and Shape:Solid
    Molecular weight:427.54
  • Bedaquiline

    CAS:
    <p>Bedaquiline, an anti-TB drug, blocks mycobacterial ATP synthesis, effective against all Mycobacterium tuberculosis states.</p>
    Formula:C32H31BrN2O2
    Purity:98% - 99.8%
    Color and Shape:Solid
    Molecular weight:555.5
  • Mirogabalin Impurity 64


    Formula:C25H34N2O2
    Molecular weight:394.56

    Ref: 4Z-M-269073

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  • Tulobuterol hydrochloride

    CAS:
    <p>Tulobuterol hydrochloride (Hokunalin) is a long-acting beta2-adrenergic receptor agonist.</p>
    Formula:C12H19Cl2NO
    Purity:99.24% - >99.99%
    Color and Shape:Appearance White Crystalline Powder
    Molecular weight:264.19
  • Benidipine

    CAS:
    <p>Benidipine: potent oral calcium blocker, boosts nitric oxide synthase, enhances coronary flow, protects heart cells post-ischemia.</p>
    Formula:C28H31N3O6
    Color and Shape:Solid
    Molecular weight:505.56
  • Barnidipine

    CAS:
    <p>Barnidipine (YM-09730-5(Free base)) is a calcium channel blocker.</p>
    Formula:C27H29N3O6
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:491.54
  • Tiagabine

    CAS:
    <p>Tiagabine (NO050328) is an Anti-epileptic Agent.</p>
    Formula:C20H25NO2S2
    Purity:99.25%
    Color and Shape:White To Off-White Crystalline Solid
    Molecular weight:375.55
  • eCF506

    CAS:
    <p>eCF506 is a potent and selective inhibitor of SRC (IC50 &lt; 0.5 nM)</p>
    Formula:C26H38N8O3
    Purity:97.85% - 98.16%
    Color and Shape:Solid
    Molecular weight:510.63
  • 1-Phenylpropane-1,2-dione

    CAS:
    <p>1-Phenylpropane-1,2-dione (Acetyl benzoyl) is a eukaryotic metabolite produced in plant metabolic reactions.</p>
    Formula:C9H8O2
    Purity:97.12%
    Color and Shape:Liquid
    Molecular weight:148.16
  • Upadacitinib Dimer


    Formula:C35H38F6N12O2
    Molecular weight:772.76

    Ref: 4Z-U-103074

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  • Morroniside

    CAS:
    <p>Morroniside regulates liver inflammation, lipid metabolism, protects against diabetic kidney damage, and guards the brain from ischemic injury.</p>
    Formula:C17H26O11
    Purity:99.70% - 99.84%
    Color and Shape:Solid
    Molecular weight:406.38
  • N-Nitroso N-Desmethyl Alcaftadine


    Formula:C18H18N4O2
    Molecular weight:322.37

    Ref: 4Z-A-199018

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  • Pyr10

    CAS:
    <p>Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.</p>
    Formula:C18H13F6N3O2S
    Purity:99.69% - 99.7%
    Color and Shape:Solid
    Molecular weight:449.37
  • Paritaprevir

    CAS:
    <p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。</p>
    Formula:C40H43N7O7S
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:765.88