Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65576 products of "Quinazoline and Quinoline Derivatives"
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2-Chlorothiophene
CAS:Controlled Product<p>Applications 2-Chlorothiophene (cas# 96-43-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C4H3ClSColor and Shape:NeatMolecular weight:118.584-Desmethyl-2-methyl Celecoxib
CAS:Controlled Product<p>Applications 4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib (C251000). It is a cyclooxygenase 2 inhibitor.<br>References Penning, T., et al.: J. Med. Chem., 40, 1347 (1997); Wesolowski, S., et al.: Bioorg. Med. Chem. Lett., 12, 267 (2002)<br></p>Formula:C17H14F3N3O2SColor and Shape:White To BeigeMolecular weight:381.373-Dimethylaminopropyl-2-benzylaminobenzoate Hydrochloride
CAS:Formula:C19H24N2O2·ClHColor and Shape:NeatMolecular weight:348.87[2-(1H-indol-3-yl)ethyl][(pyridin-4-yl)methyl]amine hydrochloride
CAS:Purity:95.0%Molecular weight:287.7900085449219N-Formyl Mirabegron
CAS:Controlled ProductFormula:C22H24N4O3SColor and Shape:NeatMolecular weight:424.516Nevirapine-d4 (cyclopropyl-2,2,3,3-d4)
CAS:Controlled Product<p>Applications Nevirapine-d4 (cyclopropyl-2,2,3,3-d4) (CAS# 1051418-95-1) is a useful isotopically labeled research compound. This can be prepared to use as non-nucleoside reverse transcriptase inhibitors.<br>References Gant, T., et.al., PCT Int.Appl., 113,(2008);<br></p>Formula:C15D4H10N4OColor and Shape:NeatMolecular weight:270.335-(1,3-Dioxolan-2-yl)-2-(4-fluorobenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:278.299987792968753-Iodothiophene-2-carboxylic acid
CAS:Formula:C5H3IO2SPurity:98%Color and Shape:SolidMolecular weight:254.04trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol
CAS:<p>Applications trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol is an impurity of Ambroxol (A575900), a bronchosecretolytic drug and a metabolite of Bromohexine.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Formula:C13H19BrN2OColor and Shape:NeatMolecular weight:299.21Tert-Butyl (1-(6-chloropyridin-3-yl)cyclobutyl)carbamate
CAS:Purity:98%Molecular weight:282.7699890136719(1S,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
CAS:Controlled Product<p>Applications An intermediate in the synthesis of thephosphodiesterase 5 inhibitor Tadalafil (T004500).<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Formula:C20H18N2O4Color and Shape:White To YellowMolecular weight:350.377-chloro-8-methyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:298.7300109863281Furagin
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Furagin (a nitrofurantoin analog) has the same efficacy in treating acute cystitis as Ciprofloxacin, however the duration of therapy is longer. Antibacterial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Agace, W., et al.: J. Clin. Invest., 92, 780 (1993); Lawrenson, R., et al.: J. Antimicrob. Chemother., 48, 895 (2001); Dalhoff, A., et al.: Lancet Infect. Dis., 3, 359 (2003); Thumbikat, P., et al.: J. Immunol., 176, 3080 (2006);<br></p>Formula:C10H8N4O5Color and Shape:NeatMolecular weight:264.19N-Nitroso Desmethyldiphenhydramine
CAS:Controlled ProductFormula:C16H18N2O2Color and Shape:NeatMolecular weight:270.3267-Hydroxy Loxapine-D8
CAS:Controlled Product<p>Applications 7-Hydroxy Loxapine-D8 is a labelled analogue of 7-Hydroxy Loxapine (H943790).<br>References Kapur, S., et al.: Am. J. Psychiatry, 154, 1525 (1997); Rivers-Bulkeley, N. & Hollender, M.: Am. J. Psychiat., 139, 1345 (1982)<br></p>Formula:C18H10D8ClN3O2Color and Shape:Dark YellowMolecular weight:351.86Levofloxacin-d8
CAS:Controlled Product<p>Applications Labelled S-(-)-Form of Ofloxacin. An antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Formula:C18H12D8FN3O4Color and Shape:Light Yellow SolidMolecular weight:369.423-Pyridin-4-yl-quinoxaline-2-carboxylic acid ethyl ester
Purity:95.0%Molecular weight:279.299011230468754-Hydroxy Phenobarbital-d5
CAS:Controlled ProductFormula:C122H5H7N2O4Color and Shape:NeatMolecular weight:253.27Levosimendan Cyanoacetamide Hydrazone Impurity
CAS:Controlled Product<p>Applications Levosimendan Cyanoacetamide Hydrazone Impurity is an impurity of Levosimendan (L378000) which is a bioactive enantiomer of racemate, Simendan. It is a positive inotropic agent with vasodilating activity and also cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Formula:C14H14N6O2Color and Shape:Off-White To Dark OrangeMolecular weight:298.3Pyrazinamide-15N,d3
CAS:Controlled Product<p>Applications Antibacterial (tuberculostatic).<br>References Weiner, I.M., et al.: J. Pharmacol. Exp. Ther., 180, 411 (1972), Feldner, E., et al.: Anal. Profiles Drug Subs., 12, 433 (1983)<br></p>Formula:C5H2D3N215NOColor and Shape:White Crystalline PowderMolecular weight:127.12Citalopram
CAS:<p>Citalopram (Lu 10-171), a serotonin and 5-HT reuptake inhibitor.Citalopram has antidepressant activity and may be used to study dementia.</p>Formula:C20H21FN2OPurity:99.78% - 99.89%Color and Shape:SolidMolecular weight:324.39Cyanuric Acid-13C3
CAS:<p>Applications Useful for diagnostic determination of Melamine and related compounds in kidney tissue.<br>References Mast, R., et al.: Food Chem. Toxicol., 21, 807 (1983), Yokley, R., et al.: J. Agric. Food Chem., 48, 3352 (2000), Ehling, S., et al.: Food Addit. Contam., 24, 1319 (2007), Vail, T., et al.: J. Anal. Toxicol., 31, 304 (2007),<br></p>Formula:C3H3N3O3Color and Shape:NeatMolecular weight:132.05Etoricoxib N1’-Oxide
CAS:Controlled Product<p>Applications Etoricoxib N1’-Oxide is an impurity of Etoricoxib (E934100).<br>References Friesen, R., et al.: Bioorg. Med. Lett., 8, 2777 (1998), Botting, J., et al.: Drugs of Today, 35, 225 (19990, Talley, J., et al.: J. Med. Chem., 43, 775 (2000),<br></p>Formula:C18H15ClN2O3SColor and Shape:NeatMolecular weight:374.84[2-(2-Methyl-1H-indol-3-yl)ethyl](pyridin-3-ylmethyl)amine dihydrochloride
CAS:Purity:95.0%Molecular weight:338.2799987792969Sodium Azide
CAS:<p>Applications Sodium azide is commonly used as a preservative in aqueous laboratory reagents and biological samples. Sodium azide’s toxicity can be attributed to its role as a reversible inhibitor of mitochondrial respiration and insulin secretion in human pancreatic cells. Acts as a catalyst for: Oxidative decarboxylation & Michael addition reactions.Used as a reagent for synthesis of Blue fluorescent copolymers; Metal phosphonates & Arenes via aminations. Actively involved in regioselective synthesis of prianosin B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chang, S. & Lamm, S.: Int. J. Toxicol., 22, 175 (2003); Misler, S., et al.: Pflügers Archiv., 421, 289 (1992)<br></p>Formula:N3·NaColor and Shape:White To Off-WhiteMolecular weight:65.016-Chloro-4-hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (Lornoxicam)
CAS:Purity:97.0%Molecular weight:371.809997558593755’-[(Desloratadine)methyl] Rupatadine
CAS:Controlled Product<p>Applications 5’-[(Desloratidine)methyl] Rupatadine is an impurity of the antihistaminic drug Rupatadine (R701650).<br>References Wang, H. et al.: Yao. Fen. Zaz., 29, 791 (2009);<br></p>Formula:C45H43Cl2N5Color and Shape:NeatMolecular weight:724.76(2R)-Vildagliptin
CAS:<p>Applications (2R)-Vildagliptin is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4) which can act as a serine exopeptidase. Aside from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C17H25N3O2Color and Shape:Off-White To Light BeigeMolecular weight:303.40Deracoxib
CAS:Controlled Product<p>Applications Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low doses, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation.<br>References Lascelles, B.D.X. et al.: J. Am. Vet. Med. Assoc., 227, 1112 (2005); Anderson, G.D. et al.: Inflam. Res., 58, 109 (2009); Brainard, B.M. et al.: Am. J. Vet. Res., 68, 251 (2007);<br></p>Formula:C17H14F3N3O3SColor and Shape:Light BrownMolecular weight:397.37Loxapine-d8 Hydrochloride
CAS:Controlled ProductFormula:C18H10D8ClN3O·xHClColor and Shape:Off-White To Light YellowMolecular weight:372.329’-Desmethyl Granisetron
CAS:Controlled Product<p>Impurity Granisetron EP Impurity C<br>Applications An impurity in the synthesis of Granisetron Hydrochloride.<br>References Nishikawa, M., et al.: Drug Metab. Pharmacokin., 19, 280 (2004), Firkusny, L., et al.: Biochem. Pharmacol., 49, 1777 (1995), Sanwald, P., et al.: Drug Metab. Dispos., 24, 602 (1996), Vanderstreene, et al.: J. Labelled Comp. Radiopharm., XLI, 3, 71 (1997),<br></p>Formula:C17H22N4OColor and Shape:White To Light YellowMolecular weight:298.386-ethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.36999511718752-Ethoxybenzamidine Hydrochloride
CAS:Controlled Product<p>Applications 2-Ethoxybenzamidine hydrochloride is an impurity of Vardenafil (diHCl salt: V098001), a phosphodiesterase type 5 inhibitor that is used to treat men of varying aetiology with erectile dysfunction.<br>References Hellstrom, W., et al.: J. Andro., 23, 763 (2002); Keating, G. & Scott, L.: Drugs, 63, 2673 (2003); Krishnaiah, C., et al.: Anal. Chem. Ind. J., 8, 284 (2009); Porst, H., et al.: Int. J. Imp. Res., 13, 192 (2001)<br></p>Formula:C9H13ClN2OColor and Shape:NeatMolecular weight:200.67Olanzapine-d3 N-Oxide
CAS:Controlled Product<p>Applications A labelled metabolite of Olanzapine.<br>References Jacobsen, E., et al.: Acta Pharmacol. Toxacol., 11, 135 (1955), Chakrabarti, J.K., et al.: J. Med. Chem., 23, 878 (1980), Luo, H., et al.: J. Pharm. Sci., 11, 1079 (1992), Moore, N.A., et al.: Curr. Opin. Invest. Drugs, 2, 281 (1993),<br></p>Formula:C17H17D3N4OSColor and Shape:NeatMolecular weight:331.458-propyl-4-(pyridine-3-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:333.38800048828125Reboxetine-d5 Mesylate
CAS:Controlled ProductFormula:C20H22D5NO6SColor and Shape:Off White SolidMolecular weight:414.53N’-(1-Methylazepan-4-yl)benzohydrazine Monohydrochloride Salt
CAS:Controlled Product<p>Impurity Azelastine EP Impurity B/Azelastine USP Related Compound B<br>Stability Hygroscopic<br>Applications An intermediate in the preparation of Azelastine (A808250(P)), which is an orally active H1-hystamine receptor antagonist and an antihistaminic.<br>References Scheffler, G. et al.: Arch. Pharm., 321, 205 (1988); Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 (1979); Chand, N., et al.: Int. J. Immunopharmacol., 7, 833 (1985)<br></p>Formula:C14H21N3O·ClHColor and Shape:Light Yellow To Dark YellowMolecular weight:283.80
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