Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65580 products of "Quinazoline and Quinoline Derivatives"
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Tris(2-ethylhexyl) 4,4',4''-((1,3,5-triazine-2,4,6-triyl)tris(azanediyl))tribenzoate
CAS:Purity:97.0%Color and Shape:Liquid, No data available.Molecular weight:823.0919799804688Ref: 10-F545236
1gTo inquire5gTo inquire10gTo inquire25gTo inquire100gTo inquire500gTo inquire100mgTo inquire500mgTo inquireLisinopril (S,S,R)-Diketopiperazine (~90%)
CAS:<p>Impurity Lisinopril EP Impurity D<br>Stability Hygroscopic<br>Applications Lisinopril (S,S,R)-Diketopiperazine (Lisinopril EP Impurity D) is an impurity of Lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor (1).<br>References 1. Goa, K. et al.: Drugs. 1996 Oct;52(4):564-88.<br></p>Formula:C21H29N3O4Purity:~90%Color and Shape:White To Off-WhiteMolecular weight:387.47N-Butyl-N-methylnitrosamine (1 mg/mL in Methanol)
CAS:Formula:C5H12N2OColor and Shape:Single SolutionMolecular weight:116.16Pyrazol-1-yl-acetonitrile
CAS:Formula:C5H5N3Purity:95.0%Color and Shape:LiquidMolecular weight:107.116Pyrimethamine-d3
CAS:Controlled Product<p>Applications Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.<br>References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004),<br></p>Formula:C12H10D3ClN4Color and Shape:Off-WhiteMolecular weight:251.734-phenyl-3-(2-thienyl)-1,2,4-triazoline-5-thione 98%
CAS:Purity:98.0%Molecular weight:259.35000610351563,6,7-Trimethyl-quinoxaline-2-carboxylic acid benzyl ester
Purity:95.0%Molecular weight:306.364990234375N-Phenoxycarbonylparoxetine
CAS:Controlled Product<p>Applications N-Phenoxycarbonylparoxetine is an impurity of Paroxetine (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>Formula:C26H24FNO5Color and Shape:NeatMolecular weight:449.47N-Boc-Sitagliptin
CAS:Controlled Product<p>Applications N-Boc-Sitagliptin is the N-Boc protected derivative of Sitagliptin (S490990), a dipeptidyl peptidase-4 inhibitor that is used for glycemic control for patients with type 2 diabetes.<br>References Aschner, P., et al.: Diabetes Care, 29, 2632 (2006); Charbonnel, B., et al.: Diabetes Care, 29, 2638 (2006)<br></p>Formula:C21H23F6N5O3Color and Shape:NeatMolecular weight:507.43rac trans-Loxoprofen Alcohol
CAS:<p>Applications The cis-alcohol metabolite of Loxoprofen (L472900).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Terada, A., et al.: J. Med. Chem., 27, 212 (1984), Sugimoto, M., et al.: Biochem. Pharmacol., 42, 2363 (1991), Riendeau, D., et al.: Bioorg. Med. Chem. Lett., 14, 1201 (2004),<br></p>Formula:C15H20O3Color and Shape:NeatMolecular weight:248.322-(5-Methylthiophen-2-yl)quinoline-4-carboxylic acid
CAS:Color and Shape:SolidMolecular weight:269.32000732421875Riociguat
CAS:Controlled Product<p>Applications Riociguat is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Formula:C20H19FN8O2Color and Shape:NeatMolecular weight:422.4157Acrivastine
CAS:Controlled Product<p>Applications Acrivastine is an allergy medication that is histamine H2 antagonists.<br>References Manna, V.K., et al.: J. Int. Med. Res., 20, 106 (1992);<br></p>Formula:C22H24N2O2Color and Shape:Off White PowderMolecular weight:348.44(1-(4-Methylphenyl)-3-(4-(methylthio)phenyl)-1H-pyrazol-4-yl)methanol
CAS:Molecular weight:310.42001342773441,1'-[(1-Methylethyl)imino]bis[3-(1-naphthalenyloxy)-2-propanol
CAS:<p>Applications 1,1'-[(1-Methylethyl)imino]bis[3-(1-naphthalenyloxy)-2-propanol is an impurity of Propranolol (P831800), an β−Adrenergic blocker used as a antihypertensive and antilanginal agent.<br>References Helboe, P., et al.: J. Chromatography., 245, 229 (1982); Helboe, P., et al.: J. Chromatography., 245, 229 (1982);<br></p>Formula:C29H33NO4Color and Shape:Off-White To BeigeMolecular weight:459.58N-Nitrosodiethylamine (1 mg/mL in Methanol)
CAS:Formula:C4H10N2OColor and Shape:Single SolutionMolecular weight:102.14Hydroxy Fasudil Hydrochloride
CAS:Controlled Product<p>Applications A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.<br>References Shimokawa, H., et al.: Cardiovasc. Res., 43, 1029 (1999), Takemoto, M., et al.: Circulation, 106, 57 (2002), Ito, K., et al.: J. Physiol., 546, 823 (2003),<br></p>Formula:C14H17N3O3S·ClHColor and Shape:NeatMolecular weight:343.83Quizalofop
CAS:<p> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C17H13ClN2O4Color and Shape:Off-White To Light YellowMolecular weight:344.75Rivastigmine N-Oxide (Technical Grade)
CAS:Controlled Product<p>Applications Rivastigmine N-Oxide is an impurity of Rivastigmine (R541000, Tartrate Salt) which is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Formula:C14H22N2O3Color and Shape:Light Yellow LiquidMolecular weight:266.34Dronedarone Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications A drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.<br>References Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008), Hoy, S., et al.: Drugs, 69, 1647 (2009), Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009),<br></p>Formula:C31H44N2O5S·ClHColor and Shape:NeatMolecular weight:593.22endo-9-Methyl-9-azabicyclo[3.3.1]nonan-3-amine
CAS:Controlled Product<p>Impurity Granisetron EP Impurity E<br>Applications Granisetron impurity E. An intermediate of Granisetron.<br>References McCallum, R., et al.: Drugs, 36, 652 (1988), Kaumann, A., et al.: Br. J. Pharmacol., 100, 879 (1990), Mohr, K., et al.: Pharmacol. Toxicol., 70, 198 (1992), Van, W.A., et al.: Nucl. Med. Biol., 21, 41 (1994), Mize, A., et al.: Brain Res., 836, 229 (1999),<br></p>Formula:C9H18N2Color and Shape:NeatMolecular weight:154.253Candoxatril
CAS:<p>Candoxatril is an inhibitor neutral endopeptidase (NEP).</p>Formula:C29H41NO7Purity:97.73% - 99.94%Color and Shape:SolidMolecular weight:515.64Reserpine
CAS:Controlled Product<p>Applications An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.<br>References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),<br></p>Formula:C33H40N2O9Color and Shape:Off-WhiteMolecular weight:608.68Fluazuron
CAS:Controlled Product<p>Applications A pesticide, like other BPUs it interferes with chitin synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yamada, R., et al.: Biosci., Biotechnol., Biochem., 70, 54 (2006), Kryger, U., et al.: Vet. Parasitol., 143, 380 (2007), Arakawa, T., et al.: App. Entomol. Zool., 43, 167 (2008),<br></p>Formula:C20H10Cl2F5N3O3Color and Shape:White To Off-WhiteMolecular weight:506.214-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazole-2-carbaldehyde
CAS:Purity:99.0%Molecular weight:304.31298828125Mosapride N-Oxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Mosapride (M731000).<br>References Chen, H., et al.: J. Pharm. Biomed. Anal., 40, 142 (2006), Pedraglio, S., et al.: J. Pharm. Biomed. Anal., 44, 665 (2007), Christopher, L., et al.: Drug Metab. Dispos., 36, 1341 (2008), Curran, M., et al.: Drugs, 68, 981 (2008),<br></p>Formula:C21H25ClFN3O4Color and Shape:NeatMolecular weight:437.89Desmethyl Amisulpride Hydrobromide
CAS:Controlled ProductFormula:C16H26BrN3O4SColor and Shape:NeatMolecular weight:436.36Famotidine Acid Methyl Ester Hydrochloride (Famotidine Impurity)
CAS:Controlled Product<p>Applications Famotidine acid methyl ester hydrochloride salt is a Famotidine (F102250) impurity.<br>References Junnarkar, G., et al.: Pharm. Res., 12, 599 (1995), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Formula:C9H14N4O2S2·ClHColor and Shape:NeatMolecular weight:310.822-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol Hemisulfate Hydrate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol Hemisulfate Hydrate is a salt form of 2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-isoquinolinetriol (CAS 94120-05-5) which is used in analytical study of identification of degradation products and process impurities from terbutaline sulfate by UHPLC-Q-TOF-MS/MS and In silico toxicity prediction.<br>References Zhou, N., et al.: Chromatographia, 80, 793 (2017)<br></p>Formula:(C13H19NO3)•H2SO4•x(H2O)Color and Shape:NeatMolecular weight:2237.3098071802Potassium Phthalimide
CAS:Controlled Product<p>Applications Potassium Phthalimide is a green, solid-base organocatalys.<br>References Kiyani, H., Ghiasi, M.: Chinese Chem. Lett., 25, 313 (2014)<br></p>Formula:C8H4NO2·KColor and Shape:NeatMolecular weight:185.22Vortioxetine Hydrobromide
CAS:<p>Applications Vortioxetine Hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Formula:C18H22N2S·BrHColor and Shape:Beige To Light YellowMolecular weight:379.358Epicaptopril
CAS:<p>Stability Air Sensitive<br>Applications Epicaptopril is an impurity of Captopril (C175750) which is an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978);<br></p>Formula:C9H15NO3SColor and Shape:White To Off-WhiteMolecular weight:217.28N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester
CAS:Controlled Product<p>Applications N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester is an impurity of the drug Valsartan (V095750), which is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Formula:C25H30N2O3Color and Shape:Colourless OilyMolecular weight:406.522-(1-phenyl-1H-pyrazol-4-yl)cyclopropane-1-carboxylic acid
CAS:Purity:95.0%Molecular weight:228.25100708007812Levofloxacin Hemihydrate
CAS:<p>Applications Levofloxacin Hemihydrate is a S-(-) form of Ofloxacin (O245750), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992); North, D.S., et al.: Pharmacotherapy, 18, 915 (1998); Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003);<br></p>Formula:C18H20FN3O4·H2OColor and Shape:Light YellowMolecular weight:740.75L-Aminobutyric Acid
CAS:<p>Applications Receptor antagonist.<br>References Porter, D.J.T., et al.: Biochem. Pharmacol., 50, 1475 (1995),<br></p>Formula:C4H9NO2Color and Shape:NeatMolecular weight:103.12Ketanserin Tartrate
CAS:Controlled Product<p>Applications Ketanserin Tartrate is used in nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis for preventing a variety of diseases ranging from cancer to ischemic injury.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gohil, V. M., et al.: Nat. Biotechnol, 28, 249 (2010)<br></p>Formula:C22H22FN3O3·C4H6O6Color and Shape:Off-WhiteMolecular weight:545.516-Hydroxy Chlorzoxazone-d2
CAS:Controlled Product<p>Applications 6-Hydroxy Chlorzoxazone-d2 is a labeled analogue of 6-Hydroxy Chlorzoxazone (H825120), A major metabolite of chlorzoxazone and formed by the actions of cytochrome P450IIE1.<br>References Twele, et al.: Arzneim.-Forsch., 32, 759 (1982); Peter, et al.: che. Res. Toxicol., 3, 566 (1990)<br></p>Formula:C7H2D2ClNO3Color and Shape:White To BrownMolecular weight:187.58rac-Ruxolitinib
CAS:Controlled Product<p>Applications rac-Ruxolitinib is the racemic analogue of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.<br>References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);<br></p>Formula:C17H18N6Color and Shape:NeatMolecular weight:306.36Niclosamide Ethanolamine Salt
CAS:<p>Applications Niclosamide Ethanolamine Salt is an ethanolamine salt of Niclosamide (N395500), which is used as an anthelmintic drug (Cestodes)<br>References Loftsson, T., et al.: J. Pharm. Sci., 85, 1017 (1996), Malik, N., et al.: Anti. Cancer Drugs, 10, 767 (1999), El-Sayed, M., et al.: Pharm. Res., 18, 23 (2001),<br></p>Formula:C13H8Cl2N2O4·C2H7NOColor and Shape:Dark YellowMolecular weight:388.203-(Morpholinosulfonyl)benzoic acid
CAS:Formula:C11H13NO5SPurity:95.0%Color and Shape:Liquid, No data available.Molecular weight:271.29Dehydronitrosonisoldipine
CAS:Controlled Product<p>Impurity Nisoldipine<br>Applications Dehydronitrosonisoldipine is an impurity of Nisoldipine (N489125). Nisoldipine is a dihydropyridine calcium channel blocker and it is antihypertensive and antianginal.<br>References Kazda, S., et al.: Arzneimittel-Forsch., 30, 2144 (1980); Pasanisi, F., et al.: Eur. J. Clin. Pharmacol., 29, 21 (1985); Lam, J., et al.: J. Am. Col. Cardiol., 6, 447 (1985)<br></p>Formula:C20H22N2O5Color and Shape:NeatMolecular weight:370.4
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