Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4948 products of "Steroids and Derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Fluocinonide 22 Methyl Homologue
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Fluocinonide 22 Methyl Homologue is a steriod and a derivative compound of Fluocinolone Acetonide (F455800) with anti-inflammatory activity.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Formula:C25H30F2O7Color and Shape:NeatMolecular weight:480.517α-Hydroxy Progesterone
CAS:Controlled Product<p>Impurity Progesterone 17?-Hydroxy Impurity<br>Applications 17α-Hydroxy Progesterone is a metabolite of Progesterone (P755900). It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Formula:C21H30O3Color and Shape:Off-WhiteMolecular weight:330.46Estradiol Enanthate
CAS:<p>Applications Estradiol Enanthate has been used as an injectable contraceptive.<br>References Coutinho, E.M., et. al.: Contraception, 73, 249 (2006)<br></p>Formula:C25H36O3Color and Shape:BeigeMolecular weight:384.55Ursodeoxycholic acid
CAS:Purity:98.0%Color and Shape:Solid, White powderMolecular weight:392.5799865722656Deflazacort
CAS:Controlled Product<p>Applications A systemic corticosteroid. A derivative of prednisolone. Used for rheumatoid arthritis and lupus.<br>References Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),<br></p>Formula:C25H31NO6Color and Shape:NeatMolecular weight:441.52Alphadolone
CAS:Controlled Product<p>Applications Alphadolone or Alfadolone (INN) is a neuroactive steroid with hypnotic effects. Alphadolone is one of the components of Althesin.<br>References Harrison, N., et al.: J. Pharmacol. Exp. Ther., 241, 346 (1987), Serrao, J., et al.: Anesthesiology, 70, 780 (1989), Mistry, D., et al.: Exp. Physiol., 75, 199 (1900),<br></p>Formula:C21H32O4Color and Shape:NeatMolecular weight:348.485(6)-Dehydro-4(5)-dihydro D-(-)-Norgestrel (>90%)
CAS:Controlled Product<p>Impurity Levonorgestrel EP Impurity P<br>Applications 5(6)-Dehydro-4(5)-dihydro D-(-)-Norgestrel (Levonorgestrel EP Impurity P) is a Norgestrel (N689500) impurity.<br></p>Formula:C21H28O2Purity:>90%Color and Shape:NeatMolecular weight:312.45Corticosterone
CAS:Controlled Product<p>Applications Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex.<br>References Schmidt, M., et al.: Endocrinol., 150, 2709 (2009), Bailey, M., et al.: J. Immunol., 182, 7888 (2009), Brunton, P., et al.: J. Neurosci., 29, 6449 (2009), Pruett, S., et al.: Toxicol. Sci., 109, 265 (2009),<br></p>Formula:C21H30O4Color and Shape:NeatMolecular weight:346.466-Dehydroprogesterone
CAS:Controlled Product<p>Applications 6-Dehydroprogesterone is an impurity found in progesterone (P755900).<br>References Maslov, L., et al.: Khimiko-Farmatsevticheskii Zhurnal, 29, 53 (1995); Sokolova, T., et al.: Khimiko-Farmatsevticheskii Zhurnal , 19, 236 (1985)<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.4511-Deoxy Prednisolone
CAS:Controlled Product<p>Impurity Prednisolone EP Impurity J<br>Applications 11-Deoxy Prednisolone (Prednisolone EP Impurity J) is a Prednisolone (P703740) derivative as a corticosteroid.<br>References Kobayashi, Y., et al.: Biol. Pharm. Bull., 16, 1175 (1993), Ogata, M., et al.: J. Pharm. Sci., 87, 91 (1998), Hou, S., et al.: J. Pharm. Biomed. Anal., 24, 371 (2001),<br></p>Formula:C21H28O4Color and Shape:Light BrownMolecular weight:344.44Norethindrone 3-Isopropyl Enol Ether
Controlled ProductFormula:C23H32O2Color and Shape:NeatMolecular weight:340.4992-Hydroxy Atorvastatin Calcium Salt
CAS:Controlled Product<p>Applications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C66H68CaF2N4O12Color and Shape:White To YellowMolecular weight:1187.356-Ketoprogesterone
CAS:Controlled Product<p>Applications 6-Ketoprogesterone is used in the synthesis and biological evaluation of steroidal deivatives as selective inhibitors of AKR1B10. AKR1B10 is a promising anti-cancer therapeutic target.<br>References Zhang, W., et al.: Steroids, 86, 39 (2014)<br></p>Formula:C21H28O3Color and Shape:NeatMolecular weight:328.455,6-trans-Vitamin D3
CAS:<p>5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol） is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.</p>Formula:C27H44OPurity:98.23%Color and Shape:SolidMolecular weight:384.645β-Dihydrocortisol-d6
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 5β-Dihydrocortisol-d6 is an isotope labelled analog of 5β-Dihydrocortisol (D448595). 5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland.<br>References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),<br></p>Formula:C21H26D6O5Color and Shape:NeatMolecular weight:370.51Betamethasone 17-Valerate
CAS:Controlled Product<p>Applications Betamethasone 17-Valerate is a corticosteroid with anti-inflammatory properties. Topical application of Betamethasone 17-Valerate has been shown to inhibit heat-induced vasodilatation in man.<br>References Banfi, S. et al.: Curr. Ther. Res., 19, 126 (1976); Ahluwalia, A. et al.: Br. J. Dermatol., 128, 45 (1993);<br></p>Formula:C27H37FO6Color and Shape:WhiteMolecular weight:476.584-Hydroxy-17β-estradiol
CAS:Controlled Product<p>Applications A metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>Formula:C18H24O3Color and Shape:FluidMolecular weight:288.3811-Ketoprogesterone
CAS:Controlled Product<p>Applications 11-Ketoprogesterone is a metabolite of Progesterone which is a steroid hormone Inducing maturation and secretory activity of the uterine endothelium. Progesterone is implicated in the etiology of breast cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formula:C21H28O3Color and Shape:NeatMolecular weight:328.453α-Hydroxy Tibolone
CAS:Controlled Product<p>Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References Belman, S., et al.: Cancer Res., 32, 450 (1972), Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1993), Hoyte, R., et al.: Steroids, 58, 13 (1993), Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (2005),<br></p>Formula:C21H30O2Color and Shape:White To Off-WhiteMolecular weight:314.4617β-Estradiol-d3 17-Acetate
CAS:Controlled Product<p>Applications Protected Estradiol.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Formula:C20H23D3O3Color and Shape:NeatMolecular weight:317.449α-Bromodesonide ~90%
CAS:Controlled Product<p>Applications 9α-Bromodesonide is a bromo derivative of Desonide (D296940); an anti-inflammatory agent.<br>References Phillips, et al.: Toxicol. Appl. Pharmacol., 20, 522 (1971); Sanen, F.J., et al.: Int. J. Clin. Pharmacol. Biopharm., 12, 174 (1975); Tarayre, J.P., et al.: Pharmacol., 19, 323 (1979)<br></p>Formula:C24H31BrO6Purity:~90%Color and Shape:YellowMolecular weight:495.4033Dienestrol
CAS:<p>Applications Dienestrol is a metabolite of Diethylstilbestrol, a non-steroidal synthetic estrogen derivative.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982); Yearley, E. et al.: J. Mol. Struct., 890, 240 (2008);<br></p>Formula:C18H18O2Color and Shape:NeatMolecular weight:266.331-Chloro Dihydro Dutasteride
CAS:<p>Impurity Dutasteride EP Impurity F<br>Applications 1-Chloro Dihydro Dutasteride (Dutateride EP Impurity F) is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative and an impurity of Dutasteride (D735000).<br></p>Formula:C27H31ClF6N2O2Color and Shape:NeatMolecular weight:564.995α-Pregnane-3β,20(S)-diol
CAS:Controlled Product<p>Applications 5α-Pregnane-3β,20(S)-diol, is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Formula:C21H36O2Color and Shape:NeatMolecular weight:320.51Spironolactone-d3
CAS:Controlled Product<p>Applications Spironolactone-d3 is the labeled analogue of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.<br>References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975)<br></p>Formula:C24H29D3O4SColor and Shape:Yellow SolidMolecular weight:419.591,2-Dihydrobudesonide (Mixture of diastereomers)
CAS:Controlled Product<p>Impurity Budesonide EP Impurity G<br>Applications 1,2-Dehydrobudesonide (Budesonide EP Impurity G) is an impurity in the synthesis of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Formula:C25H36O6Color and Shape:NeatMolecular weight:432.55Budesonide-d6
CAS:Controlled Product<p>Applications Labelled Budesonide, a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Formula:C25H28D6O6Color and Shape:NeatMolecular weight:436.57Algestone
CAS:Controlled Product<p>Applications A pregnane steroid, its acetonide is used as anti-inflammatory drug (topical) and combination with enanthate as injectable contraceptive.<br>References Hydorn, A., et al.: Steroids, 3, 493 (1964), Plesner, R., et al.: Acta Endorcinol., 61, 494 (1969),<br></p>Formula:C21H30O4Color and Shape:NeatMolecular weight:346.4625-Hydroxy Cholesterol
CAS:<p>Applications An oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.<br>References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);<br></p>Formula:C27H46O2Color and Shape:NeatMolecular weight:402.6522α-Hydroxy Cholesterol
CAS:Controlled Product<p>Applications The 22R-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.<br>References Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997), Mackay, C., et al.: Nature Immunol., 2, 95 (2001), Navenot, J., et al.: J. Mol. Biol., 313, 1181 (2001),<br></p>Formula:C27H46O2Color and Shape:NeatMolecular weight:402.65Norgestrel
CAS:Controlled Product<p>Applications Norgestrel is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.<br>References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),<br></p>Formula:C21H28O2Color and Shape:White To Off-WhiteMolecular weight:312.4517α-Dutasteride
CAS:Controlled Product<p>Impurity Dutateride EP Impurity E<br>Applications 17α-Dutasteride (Dutateride EP Impurity E) is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000).<br></p>Formula:C27H30F6N2O2Color and Shape:Dark Orange Colour SolidMolecular weight:528.53Norethindrone-d7 (Major)
CAS:Controlled ProductFormula:C20H19D7O2Color and Shape:NeatMolecular weight:305.46Testosterone 17-O-Acetate
CAS:Controlled Product<p>Applications An Androgen.Controlled substance.<br>References Alikhan, A., et al.: J. App. Toxicol., 29, 590 (2009), Christy H., et al.: J. Steroid Biochem. Mol. Biol., 116, 171 (2009), Li, C., et al.: Steroids, 75, 859 (2010),<br></p>Formula:C21H30O3Color and Shape:NeatMolecular weight:330.466β-Hydroxy Testosterone
CAS:Controlled ProductFormula:C19H28O3Color and Shape:WhiteMolecular weight:304.42Testosterone-d3 (100 ug/mL in Acetonitrile)
CAS:Controlled ProductFormula:C192H3H25O2Color and Shape:Single SolutionMolecular weight:291.4417α-Hydroxy Progesterone-d8
CAS:Controlled Product<p>Applications Labelled 17α-Hydroxyprogesterone (H952330). 17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Formula:C212H8H22O3Color and Shape:Off-WhiteMolecular weight:338.5121-Acetoxy-11β-hydroxy-16α,17α-propylmethylenedioxpregna-1,4-diene-3,20-dione
CAS:Controlled ProductFormula:C27H36O7Color and Shape:Off WhiteMolecular weight:472.57Estradiol Benzoate
CAS:<p>Applications Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.<br>References MacLusky, N., et al.: Endocrinology, 106, 192 (1980), Apostolakis, E., et al.: J. Neurosci., 16, 4823 (1996), Guarraci, F., et al.: Brain Res., 999, 40 (2004), Petralia, S., et al.: J. Neuroendocrinol., 18, 902 (2006),<br></p>Formula:C25H28O3Color and Shape:WhiteMolecular weight:376.4917β-Estradiol-16,16,17-d3 3-Benzoate
CAS:Controlled Product<p>Applications 17beta-Estradiol-16,16,17-d3 3-Benzoate (CAS# 1192354-74-7) is a useful isotopically labeled research compound.<br></p>Formula:C25H25D3O3Color and Shape:NeatMolecular weight:379.51Estriol Trisulfate Trisodium Salt
CAS:<p>Applications Estriol Trisulfate Trisodium Salt (cas# 100940-55-4) is a compound useful in organic synthesis.<br></p>Formula:C18H21Na3O12S3Color and Shape:NeatMolecular weight:594.52Equilin 3-Sulfate Sodium Salt (Stabilized with TRIS, 50% w/w)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Equilin 3-Sulfate Sodium Salt, is a metabolite of Equilin (E592800).<br>References Hajdu, A., et al.: Experientia, 27, 956 (1971), Adams, W.P., et al.: J. Pharma. Sci., 68, 986 (1979),<br></p>Formula:C18H19O5S·NaColor and Shape:NeatMolecular weight:370.401α-(Chloromethyl) Chlormadinone Acetate
CAS:Controlled Product<p>(1α)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)-pregna-4,6-<br>diene-3,20-dione; 6-Chloro-1α-(chloromethyl)-17-<br>hydroxypregna-4,6-diene-3,20-dione Acetate; Cyproterone<br>Acetate EP Impurity C</p>Formula:C24H30Cl2O4Color and Shape:NeatMolecular weight:453.4017-Deoxy Cortienic Acid
CAS:<p>Applications 17-Deoxy Cortienic Acid was used in the synthetic preparation of macrolactonolides, a class of potential antiinflammatory drugs.<br>References Tomaskovic, L., et al.: Bioorg. Med. Chem., 21, 321 (2013); Little, R.J., et al.: Pharma. Res., 16, 961 (1999); Manz. B., et al.: J. Steroid. Biochem., 17, 335 (1982);<br></p>Formula:C20H28O4Color and Shape:NeatMolecular weight:332.435β-Pregnan-3α-ol-20-one
CAS:Controlled Product<p>Applications A hyponotic-anaesthetic agent.<br>References Gyermek, et al.: J. Med. Chem., 11, 117 (1968)<br></p>Formula:C21H34O2Color and Shape:NeatMolecular weight:318.504-Hydroxy Estrone
CAS:Controlled ProductFormula:C18H22O3Color and Shape:Light Brown SolidMolecular weight:286.37Estradiol-13C2 17-Benzoate
CAS:<p>Applications Estradiol-13C2 17-Benzoate is an intermediate in the synthesis of 17β-Estradiol-13C2 (E888003). Isotope labelled 17β-Estradiol (E888000) is the major estrogen (1) secreted by the premenopausal ovary (2).<br></p>Formula:C2313C2H28O3Purity:>90%Color and Shape:NeatMolecular weight:378.47trans-Diethyl Stilbestrol
CAS:Controlled Product<p>Stability And Ether., Chloroform, Isomerizes Rapidly In Benzene<br>Applications A synthetic, nonsteroidal estrogen.Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References White, W. A. et. al.: J. Agric. Food Chem. 19(2), 388-390 (1971).<br></p>Formula:C18H20O2Color and Shape:NeatMolecular weight:268.35Hexestrol-d4
CAS:Controlled Product<p>Applications Estrogen; antineoplastic (hormonal).<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 11, 347 (1982),<br></p>Formula:C182H4H18O2Color and Shape:White To Off-WhiteMolecular weight:274.395a-Dihydrolevonorgestrel
CAS:Controlled Product<p>Applications 5α-Dihydrolevonorgestrel is the reduced analogue of levonorgestrel (N689510), a safe, tolerated and effective emergency contraceptive for women.<br>References Cabeza, M., et al.: Steroids., 60, 630 (1995); Lemus, A.E., et al.: J. Steroid. Biochem. Molec. Biol., 41,881 (1992); Bergink. E.W., et al.: J. Steroids. Biochem., 14, 175 (1981);<br></p>Formula:C21H30O2Color and Shape:NeatMolecular weight:314.46Fluocinolone Acetonide-21-aldehyde
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity D<br>Stability Hygroscopic<br>Applications Fluocinolone acetonide-21-aldehyde, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Formula:C24H28F2O6Color and Shape:White To Light YellowMolecular weight:450.47Aldosterone-d7 (Major)
CAS:Controlled ProductFormula:C21H21D7O5Color and Shape:NeatMolecular weight:367.499-Dehydroandrostenedione
CAS:Controlled Product<p>Applications 9-Dehydroandrostenedione, is a dehydrated analogue of 4-Androsten-11β-ol-3,17-dione (A637705). It is a steroid hormone, and also a derivative of Androstenedione (A637550), which is a Testosterone precursor and metabolite with androgenic activity.<br>References Walker, V.R., et al.: Anal. Biopchem., 234, 194 (1996), King, D.S., et al.: J. Am. Med. Assoc., 281, 2020 (1999), Grosser, B. et al.: Steroids. 8, 915 (1966);<br></p>Formula:C19H24O2Color and Shape:NeatMolecular weight:284.39δ5-Avenasterol (E/Z mixture)
CAS:<p>Applications Δ5-Avenasterol is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone.<br>References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)<br></p>Formula:C29H48OColor and Shape:White To Off-WhiteMolecular weight:412.6917a-Dihydro Equilenin
CAS:Controlled Product<p>Applications The 17α-metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formula:C18H20O2Color and Shape:NeatMolecular weight:268.356-β-Hydroxy Eplerenone
CAS:<p>Applications A metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br></p>Formula:C24H30O7Color and Shape:White To Off-WhiteMolecular weight:430.49Dydrogesterone
CAS:Controlled Product<p>Applications A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.<br>References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.45O,O-Dimethyl Methylphosphonate
CAS:Controlled Product<p>Applications O,O-Dimethyl Methylphosphonate is a commercially used preignition additive for gasoline, anti-foaming agent, plasticizer, stabilizer and antistatic agents.<br>References Jang, S.H., et al.: J. Korean. Phy. Soc., 55, 294 (2009); Schneider, B.B., et al.: Int. J. Mass. Spectro., 298, 45 (2010);<br></p>Formula:C3H9O3PColor and Shape:NeatMolecular weight:124.076(17α)-19-Norpregna-3,5-dien-20-yne-3,17-diol 3,17-Diacetate
CAS:Controlled Product<p>Applications Inhibits the development of uterus decidua. Estrogenic activity.<br>References Pollard, I. & Martin, L.; Steroids, 11, 897 (1968)<br></p>Formula:C24H30O4Color and Shape:White To Light YellowMolecular weight:382.4914,15-Dehydro Triamcinolone Acetonide
CAS:Controlled Product<p>Applications 14,15-Dehydro Triamcinolone Acetonide is a derivative of Triamcinolone acetonide. A corticosteroid.<br></p>Formula:C24H29FO6Color and Shape:Light YellowMolecular weight:432.4811-β-Hydroxyandrosterone
CAS:<p>Applications 11-β-Hydroxyandrosterone is a steroid metabolite of Andosterone (A637535), and is one of the major hormones monitored (in urine) when testing athletes for anabolic steroid usage.<br>References Flenker, U., et al.: Steroids, 73, 408 (2008); Norli, H., et al.: J. Steroid Biochem., 24, 83 (1995)<br></p>Formula:C19H30O3Color and Shape:NeatMolecular weight:306.44Spironolactone
CAS:Controlled Product<p>Applications It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.<br>References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),<br></p>Formula:C24H32O4SColor and Shape:Off-WhiteMolecular weight:416.57Testosterone Sulfate Triethylamine Salt
CAS:Controlled Product<p>Applications A metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.<br>References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);<br></p>Formula:C25H43NO5SColor and Shape:NeatMolecular weight:469.682-Hydroxy Atorvastatin-d5 Sodium Salt
CAS:Controlled Product<p>Applications A deuterated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Formula:C332H5H28FN2O6·2NaColor and Shape:NeatMolecular weight:623.637α-Thiomethyl Spironolactone-d7 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Spironolactone.<br>References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),<br></p>Formula:C23H25D7O3SColor and Shape:NeatMolecular weight:395.617α-Hydroxy Cholesterol
CAS:Controlled Product<p>Applications Secondary metabolite of Cholesterol.<br>References Notaro, G., et al.: J. Nat. Prod., 55, 1588 (1992), Aydogmus, Z., et al.: Nat. Prod. Res., 18, 43 (2004), Mao, S., et al.: J. Nat. Prod ., 69, 1209 (2006), Shoji, T., et al.: J. Agric. Food Chem., 54, 884 (2006),<br></p>Formula:C27H46O2Color and Shape:Off-WhiteMolecular weight:402.65Clobetasone 17-Propionate
CAS:Controlled Product<p>Impurity Clobetasone Butyrate EP Impurity H<br>Applications Clobetasone-17-propionate is derived from Clobetasol (Clobetasol Propionate EP Impurity G) (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986)<br></p>Formula:C25H30ClFO5Color and Shape:NeatMolecular weight:464.95Isovitamin D3 (90%)
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Isovitamin D3 is a metabolite of Vitamin D. Studies show that Isovitamin D3 is biologically active in normal rats but inactive in anephric rats.<br>References Holick, M.F. et al.: Science, 180, 964 (1973); Wilczek, H. et al.: Prak. Lek., 59, 794 (1979);<br></p>Formula:C27H44OPurity:90%Color and Shape:NeatMolecular weight:384.64N-[4-Nitro-3-(trifluoromethyl)phenyl]-propanamide
CAS:Controlled Product<p>Applications N-[4-Nitro-3-(trifluoromethyl)phenyl]-propanamide is an impurity of flutamide (F598850). Flutamide is a nonsteroidal antiandrogen drug; antineoplastic (hormonal).<br>References Neri, et al.: Endocrinology, 91, 427 (1972), Sogani, P.C., et al.: J. Urol., 122, 640 (1979), Greenway, B.A., et al.: Br. Med. J., 316, 1935 (1998),<br></p>Formula:C10H9F3N2O3Color and Shape:Light Yellow SolidMolecular weight:262.194-Hydroxy-17β-estradiol-16,16,17-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>Formula:C182H5H19O3Color and Shape:NeatMolecular weight:293.41Eplerenone-d3
CAS:Controlled Product<p>Applications Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Formula:C24H27D3O6Color and Shape:NeatMolecular weight:417.51(3a)-Allopregnanolone
CAS:Controlled Product<p>Applications (3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain. In 2019, the US Food and Drug Administration approved (3α)-Allopregnanolone as an intravenous infusion for treating postpartum depression.<br>References Puja, G. et al.: Neuron, 4, 759 (1990); Belelli, D. et ael. Neurosteroid, 6, 565 (2006); Viapiano, M. et al.: Neurochem. Res., 23, 155 (1998);<br></p>Formula:C21H34O2Color and Shape:White To Off-WhiteMolecular weight:318.49Dutasteride a-Dimer (~90%)
CAS:Controlled Product<p>Applications Dutasteride α-Dimer is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formula:C46H55F6N3O4Purity:~90%Color and Shape:Off-WhiteMolecular weight:827.94Betamethasone 6α-Bromo 17-Valerate
Controlled Product<p>Applications Betamethasone 6α-Bromo 17-Valerate is an impurity of Betamethasone (B327000), which is a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Formula:C27H36BrFO6Color and Shape:NeatMolecular weight:555.479,11-Anhydrobudesonide(Mixture of Diastereomers)
CAS:Controlled Product<p>Impurity Budesonide EP Impurity H<br>Applications 9,11-Anhydrobudesonide (Budesonide EP Impurity H) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>Formula:C25H32O5Color and Shape:NeatMolecular weight:412.52Isoflupredone
CAS:Controlled Product<p>Applications Anti-inflammatory.<br>References Buchwald, P., et al.: Steroids, 73, 193 (2008), Holbeck, S., et al.: Mol. Endocrinol., 24, 1287 (2010),<br></p>Formula:C21H27FO5Color and Shape:NeatMolecular weight:378.43Desmosterol
CAS:<p>Applications A metabolite of Cholesterol (C432501).<br>References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),<br></p>Formula:C27H44OColor and Shape:White To Off-WhiteMolecular weight:384.64(3b)-Allopregnanolone Sulfate Sodium Salt
CAS:Controlled Product<p>Applications (3β)-Allopregnanolone Sulfate is the sulfate conjugate of (3β)-Allopregnanolone, a metabolite of progesterone and a potent inhibitory modulator of GABAA receptors.<br>References Li, P. et al.: Mol. Pharmacol., 77, 539 (2010); El-Etr, M. et al.: Brain Res., 790, 334 (1998); Park-Chung, M. et al.: Brain Res., 830, 72 (1999);<br></p>Formula:C21H33NaO5SColor and Shape:NeatMolecular weight:420.54Cortisol 21-Sulfate Potassium Salt
CAS:Controlled Product<p>Applications Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).<br>References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),<br></p>Formula:C21H29KO8SColor and Shape:NeatMolecular weight:480.6121-Chloro-9-fluoro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-Propionate (>90%)
CAS:<p>Impurity Clobetasol Propionate EP Impurity C<br>Applications 21-Chloro-9-fluoro-11β,17-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17-Propionate (Clobetasol Propionate EP Impurity C) is an impurity of Clobetasol 17-Propionate (C583500), an topical corticosteroid with anti-inflammatory properties.<br>References Sugai, S., et al.: Chem. Pharma. Bull., 31, 12 (1983);<br></p>Formula:C25H32ClFO5Color and Shape:NeatMolecular weight:466.974-Hydroxy Estrone 1-N7-Guanine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Formula:C23H25N5O4Color and Shape:NeatMolecular weight:435.48Triamcinolone 16,21-Diacetate
CAS:Controlled Product<p>Applications A glucocorticoid that inhibits prolyl hydroxylase activity and used as an antiasthmatic and antiallergic drug.<br>References Kos-Kudla, B. et al.; J. Clin. Pharm. Ther., 28, 103 (2003); Hochhaus, G. et al.; Pharmaceut. Res., 7, 558 (1990); Counts, D. et al.: Mol. Pharmacol., 15, 99 (1979); Cutroneo, K. et al.; Mol. Pharmacol., 11, 632 (1975); Cutroneo, K. et al.: Mol. Pharmacol., 11, 44 (1975)<br></p>Formula:C25H31FO8Color and Shape:NeatMolecular weight:478.514-Hydroxy Atorvastatin-d5 Disodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A deuterated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Formula:C33H28D5FN2Na2O6Color and Shape:NeatMolecular weight:623.63Z,Z-Dienestrol-D6
CAS:Controlled Product<p>Applications A labelled metabolite of Diethylstilbestrol.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982),<br></p>Formula:C18H12D6O2Color and Shape:NeatMolecular weight:272.376a,9a-Difluoroprednisolone 21-Acetate
CAS:Controlled Product<p>Applications 6α,9α-Difluoroprednisolone 21-Acetate, is an impurity of Difluprednate (D445925), which is shown to have antiinflammatory activity.<br>References Toscano L., et al.: J. Med. chem., 20, 213 (1977);<br></p>Formula:C23H28F2O6Color and Shape:White To Off-WhiteMolecular weight:438.465β-Finasteride
CAS:Controlled Product<p>Applications 5β-Finasteride is an azasteroid and 5β-isomeric impurity of Finasteride (F342000).<br>References Cendrowska, I. et al.: J. Liq. Chrom. Rel. Technol., 22, 2259 (1999);<br></p>Formula:C23H36N2O2Color and Shape:Off-WhiteMolecular weight:372.54Medroxy Progesterone-d3
CAS:Controlled Product<p>Applications Labelled Medroxyprogesterone, an orally active progestogen used in hormone replacement therepy (HRT), in the past has been used as a component of oral contraceptives.<br>References Pan, Q., et al.: Mol. Hum. Reprod., 13, 797 (2007), Matsson, P., et al.: J. Pharmacol. Exp. Ther., 323, 19 (2007), Jukosky, J.A., et al.: Bull. Environ. Contam. Toxicol., 81, 230 (2008), Cherkasov, A., et al.: J. Med. Chem., 51, 2047 (2008),<br></p>Formula:C22H29D3O3Color and Shape:NeatMolecular weight:347.5111-Deoxy Corticosterone
CAS:Controlled Product<p>Applications A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).<br>References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),<br></p>Formula:C21H30O3Color and Shape:White To Light YellowMolecular weight:330.46Oxandrolone
CAS:Controlled Product<p>Applications A synthetic, anabolic steroid. Used to promote muscle growth and combat involuntary weight loss. It has also been used to treat cases of osteoporosis.<br>References Cadwallader, A., et al.: Mol. Pharm., 7, 689 (2010), Amundson, E., et al.: J. Clin. Endocrinol. Metabol., 95, 1355 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010),<br></p>Formula:C19H30O3Color and Shape:White To Off-WhiteMolecular weight:306.44Cholesterol-d7
CAS:Controlled Product<p>Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Formula:C272H7H39OColor and Shape:NeatMolecular weight:393.70Testosterone β-D-Glucuronide Monosodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Metabolite of Testosterone (T155000).<br>References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug Metab. Disposition, 37, 417 (2009),<br></p>Formula:C25H35O8·NaColor and Shape:White To Off-WhiteMolecular weight:486.534α-Hydroxy Cholesterol
CAS:Controlled Product<p>Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Formula:C27H46O2Color and Shape:NeatMolecular weight:402.65Testosterone Enanthate
CAS:Controlled Product<p>Applications Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Formula:C26H40O3Color and Shape:Colourless To Off-WhiteMolecular weight:400.594’-Hydroxy Dutasteride
Controlled Product<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formula:C27H30F6N2O3Color and Shape:NeatMolecular weight:544.53
![N-[4-Nitro-3-(trifluoromethyl)phenyl]-propanamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FN596850.webp&w=3840&q=75)
