APIs for research and impurities

Please enquire for more information about Depyrazine 6,8-diaminophenyl varenicline hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Lactiflorin is a natural compound that has been found to have potent inhibitory effects on cancer cells. This medicinal plant extract is commonly used in Chinese traditional medicine as an anticancer agent. Lactiflorin has been shown to induce cell cycle arrest and promote apoptosis in human cancer cells by inhibiting the activity of protein kinases, which are essential for tumor growth and survival. Additionally, lactiflorin analogs have been developed with even greater potency against cancer cells. In preclinical studies, lactiflorin and its derivatives have demonstrated promising results as potential therapeutic inhibitors for various types of cancers. Furthermore, lactiflorin has also shown potential as a non-invasive biomarker for early detection of certain cancers through analysis of urine samples.

Isoquinine is a potent compound with promising anticancer activity. It has been shown to have inhibitory activity against protein kinases, which are enzymes involved in the regulation of cell cycle and proliferation. Isoquinine can act as an inhibitor of kinase inhibitors, leading to a decrease in tumor growth and inducing apoptosis in tumor cells. In addition to its potential as an anticancer agent, Isoquinine has also shown antitumor activity against Alzheimer's disease. This compound is a carboxylic acid that can bind to specific targets within cells and inhibit their function, making it a promising candidate for future drug development. Its unique mechanism of action makes it an attractive target for further study and exploration.

Paritaprevir is a medicinal compound that acts as an inhibitor of protein kinases. It has been shown to be effective against various types of cancer cells, including those found in the urine and tumors. Paritaprevir is an analog of a Chinese anticancer compound and has been shown to induce apoptosis in human cancer cells. This potent kinase inhibitor selectively targets specific kinases involved in cancer cell proliferation, making it a promising candidate for the treatment of cancer. Its ability to inhibit kinases also makes it an attractive therapeutic option for other diseases that involve aberrant kinase activity.

Olaparib impurity 14 is a metabolite of olaparib. Olaparib is a drug used to treat cancer by inhibiting the activity of PARP1, an enzyme that repairs DNA damage. This impurity is a compound that can be synthesized in high purity and quality with a custom synthesis service. It has been shown to have niche applications in pharmacopoeia, drug development, and analytical studies.

Please enquire for more information about Rosuvastatin EP Impurity C sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-(1-Hydroxy-9H-fluoren-2-yl)-acetamide is an anticancer agent that functions as a kinase inhibitor. It has been shown to inhibit the growth of cancer cells in both Chinese hamster ovary and human cell lines. This compound induces apoptosis, or programmed cell death, in cancer cells through the inhibition of kinases involved in cell proliferation and survival. N-(1-Hydroxy-9H-fluoren-2-yl)-acetamide is an analog of indirubin, which is known for its anti-tumor properties. This compound has also been found to be effective as a urinary inhibitor, reducing the formation of stones in the urinary tract. Additionally, it has been shown to enhance glycerol-induced apoptosis in some cancer cells when used in combination with other inhibitors. Overall, N-(1-Hydroxy-9H-fluoren-2-yl)-acetamide holds great promise as a potential treatment option for various types of

Ulimorelin hydrochloride hydrate is an inhibitor that has been shown to selectively induce apoptosis in cancer cells. This medicinal compound is a protein analog that inhibits the activity of kinases, which are enzymes that play a critical role in tumor growth and progression. Ulimorelin hydrochloride hydrate has been tested on human cancer cell lines and has demonstrated potent anticancer activity. Additionally, it has been found to have inhibitory effects on Chinese hamster ovary (CHO) cells, which suggests potential therapeutic applications beyond cancer treatment. Ulimorelin hydrochloride hydrate is excreted primarily via urine and may be the basis for future research in developing new kinase inhibitors for treating various types of cancer.

2-Bromo-4-chloro-N-methyl-N-phenyl-butanamide is an analog of saxagliptin, a protein inhibitor that has been shown to induce apoptosis in cancer cells. This compound has demonstrated potent anticancer activity in vitro and in vivo, inhibiting the growth of tumor cells by targeting kinases involved in cell proliferation and survival. It has also been found to be effective against a variety of human cancer types, including breast, prostate, and lung cancer. Additionally, 2-Bromo-4-chloro-N-methyl-N-phenyl-butanamide has been shown to have potential as a urine biomarker for detecting early-stage Chinese bladder cancer. Overall, this compound shows promise as a potent inhibitor of cancer cell growth and may have important applications in the development of novel anticancer therapies.

(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.

Applications 3,5-Diiodo-4’-O-methyl Thyroacetic Acid Ethyl Ester is a derivative of 3,5-Diiodo Thyroacetic Acid (D455140), the acetic acid analog of Thyroxine (T425601). It is a reactant in the preparation of bifunctional thyrointegrin inhibitors, thyroxine (T425601) and triiodothyronine (T795380).
References Bridoux, A. et al.: J. Enz. Inh. Med. Chem., 26, 871 (2011); Wilkinson, J.: Biochem. J., 63, 601 (1956); Wilkinson, J.: Chem. Ind., 1352 (1955)

Applications epi-Glycochenodeoxycholic Acid Sodium Salt-d7 is a labelled epimer analogue of Glycochenodeoxycholic Acid Sodium Salt (G641255), which is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005);

Please enquire for more information about Vildagliptin carboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

(24R)-Calcipotriene is a synthetic analog of calcitriol, the active form of vitamin D3. It is a proapoptotic agent that inhibits tumor growth by causing mitochondrial membrane potential collapse in cancer cells. (24R)-Calcipotriene has been shown to inhibit tumor growth in animals and human cells in vitro. This drug also potentiates the effects of other anticancer drugs such as doxorubicin and etoposide. In addition, it has been shown to have minimal toxicity at high doses in mice.

Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.

Amiodarone impurity E is a nucleophilic compound that is synthesized by the acylation of a diazonium salt with an amine. It has been shown to be active against staphylococci, but not against subtilis. The reaction may be catalyzed by acid or chloride. Amiodarone impurity E is also demethylated and dehydrated to form the final product, amiodarone.

5,6-Dehydro-tigecycline is a synthetic antibiotic that is used for the treatment of multi-drug resistant bacterial infections. 5,6-Dehydro-tigecycline binds to the 30S ribosomal subunit and blocks protein synthesis by inhibiting peptidyl transferase activity. This drug has been shown to be effective in treating methicillin resistant Staphylococcus aureus (MRSA) infections. 5,6-Dehydro-tigecycline also inhibits the growth of Mycobacterium tuberculosis and Mycobacterium avium complex, although it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Metabolism studies have shown that 5,6-Dehydro-tigecycline undergoes oxidative metabolism via CYP450 enzymes to form reactive metabolites like N2-[(

3-Chloro-4-hydroxyacetanilide is a chemical compound that belongs to the class of acetanilides. It has long-term toxicity and is used as a drug substance in the production of aniline derivatives. 3-Chloro-4-hydroxyacetanilide has been shown to be carcinogenic in hamsters. The long term exposure to this chemical was shown to cause liver damage and increased incidence of tumours in rats. This drug also contains impurities and traces of chloride, chlorine, and thionyl chloride, which are toxic substances that can cause irritation or burns on contact with skin or eyes.

Gentamicin Impurity

Please enquire for more information about Mycophenolate mofetil EP Impurity C including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methylacrylamide is a cavity inhibitor that has inhibitory activity against polymerization. It also reacts with chloride and alkene, which can be used to synthesize an amide. N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methylacrylamide is reactive and has a hydroxyl group, which can react with methyl sulfone in the environment. This agent has been shown to have anticancer activity in cell lines and tumor models.

Clarithromycin EP Impurity A is an analytical standard for clarithromycin. Clarithromycin EP Impurity A is a white to off-white powder that is soluble in methanol, acetone, and chloroform. It has a molecular weight of 459.23 Da and the chemical formula C18H26N2O5S. Clarithromycin EP Impurity A is an impurity found in clarithromycin that has been isolated from the product by high-performance liquid chromatography (HPLC) and confirmed by nuclear magnetic resonance spectroscopy (NMR). Clarithromycin EP Impurity A can be used as a reference standard for pharmacopoeia testing or as a research and development sample for drug development. It can also be synthesized from natural or synthetic sources.

1-Oxo mirtazapine is a metabolite of mirtazapine. It is a synthetic compound and is not found in nature. This product is a research and development impurity standard for the preparation of drug product, which has been synthesized to be highly pure. The material is used for drug development, including pharmacopoeia requirements for analytical studies and metabolism studies. 1-Oxo mirtazapine has been shown to have niche applications in pharmacopoeia and as an HPLC standard.