APIs for research and impurities

<p>N9-Des(4-acetoxy-3-(acetoxymethyl)but-1-yl) N7-[4-acetoxy-3-(acetoxymethyl)but-1-yl] famciclovir is an analytical standard that is used for drug development and as an impurity in the production of famciclovir. It has a purity of 99.0% and a melting point of 176°C. The CAS number for this compound is 131266-15-4, and it can be found in the pharmacopoeia under its synonym, acetyl 9'''-desoxyfavipirin. This chemical has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1), but not against HSV2 or cytomegalovirus (CMV).</p>

<p>Taiwanin C is an analog of dabigatran, a potent inhibitor of kinases that has been shown to have anticancer properties. It has been found to inhibit the growth of tumor cells in vitro and in vivo, inducing apoptosis and reducing protein expression. Taiwanin C has also shown promising results in inhibiting the activity of various kinases involved in cancer cell proliferation and survival. This compound is derived from Chinese herbal medicine and can be detected in urine after administration. Its potential as an anticancer agent makes it a promising area for further research into new cancer therapies.</p>

<p>Please enquire for more information about Clobetasol Propionate - Impurity D including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>α,α'-Bis[(2-methoxyphenoxy)methyl]-1,4-piperazinediethanol is an impurity in the drug ranolazine. It is a dimer of the active compound α,α'-bis[2-(methoxy)phenoxy]methyl-1,4-piperazine. This impurity has been shown to have antiarrhythmic properties.</p>

<p>Telmisartan is a drug that belongs to the class of angiotensin II receptor antagonists and is used in the treatment of hypertension. Telmisartan can be quantitatively analyzed with high sensitivity by liquid chromatography. Impurities in telmisartan can be analyzed qualitatively and quantitatively by liquid chromatography, which requires a shorter time than GC analysis.</p>

<p>8-(2-Pyrimidinyl)-8-aza-5-azoniaspiro[4.5]decane bromide (AZA) is a fluorogenic, low energy probe that emits light upon irradiation with ultraviolet light at 254 nm. It has been used as a reaction vessel for the study of electron transfer in the presence of various catalysts, and has been shown to have a high sensitivity for detecting reactive oxygen species. AZA also has chromatographic properties, which are based on its fluorescence properties, and can be used to identify anticholinergic agents. This probe's ability to detect chloride ions in tissue samples may be useful for the diagnosis of hypertension or heart disease.<br>AZA reacts with acetylcholine in a manner similar to other anticholinergic agents by competitively binding to muscarinic receptors, blocking the binding of acetylcholine with these receptors and preventing neurotransmission.</p>

<p>Chlorpromazine is a cholinergic drug that is used to treat psychiatric patients. It has been shown to be effective in the treatment of schizophrenia and other psychotic disorders. Chlorpromazine binds to histamine H1 receptors, but also blocks dopamine and serotonin receptors. This drug has a long half-life in plasma (14.4 hours) and tissues, which may be due to its metabolites. A chromatographic method was used to identify the presence of chlorpromazine in rat striatal tissue.</p>

<p>Methapyrilene fumarate is a synthetic maleate salt of methapyrilene. This drug is used in the treatment of high blood pressure. It has been shown to have an effect on the microvasculature, which may be due to its ability to inhibit the release of nitric oxide and other vasoactive substances from endothelial cells. Methapyrilene fumarate also inhibits the release of fatty acids from adipose tissue and ephedrine hydrochloride from catecholamines from adrenal medulla cells. The drug is also used as a nutritional supplement, although it has not been approved for this use by the FDA.</p>

<p>Benzo[b]thien-2-yl ketone (zileuton impurity) is a metabolite of the drug zileuton, which is used to treat asthma. Benzo[b]thien-2-yl ketone is formed by the oxidation of benzo[b]thiophene in the presence of cytochrome P450 enzyme system. It has been found to have anti-inflammatory properties and may be useful for treating asthma. This product is available as an analytical standard for HPLC, or as a custom synthesis for research and development.</p>

<p>N-Des[2-(1-methyl-2-pyrrolidinyl)ethyl] udenafil is an impurity in the drug product. It is a synthetic compound and is a metabolite of the drug product. N-Des[2-(1-methyl-2-pyrrolidinyl)ethyl] udenafil is present as a byproduct of the metabolism of the active ingredient. The CAS number for this substance is 319491-68-4. This impurity has been observed to have niche applications in research and development and analytical studies. It has also been found to be pharmacopoeia grade, which means it meets or exceeds purity standards set by regulatory authorities.</p>

<p>PBDE 197 is a medicinal compound that has shown potential as an anticancer agent. It is a kinase inhibitor, which means it blocks certain enzymes that are involved in cell signaling and growth. PBDE 197 has been found to induce apoptosis, or programmed cell death, in human cancer cells. This compound is an analog of other kinase inhibitors and has demonstrated potent inhibitory effects on protein kinases in vitro. In animal studies, PBDE 197 has shown promising results as a tumor growth inhibitor. It is excreted through urine and may have potential as a therapeutic option for cancer patients.</p>

<p>Atropine impurity G is a natural metabolite that is found in the body as an impurity of atropine. It is a synthetic drug product that is used as an analytical standard for the quantification of atropine and other drugs. Atropine impurity G has been shown to inhibit metabolism studies, which may be due to its ability to inhibit CYP3A4 activity. This impurity can be detected using HPLC with UV detection.</p>

<p>Bletilol B is a medicinal compound that has been shown to induce apoptosis in human cancer cells. It acts as a cyclin-dependent kinase (CDK) inhibitor, disrupting the cell cycle and preventing tumor growth. Bletilol B has been tested on various cancer cell lines and has demonstrated potent anticancer activity by inhibiting the proliferation of cancer cells. This compound works by binding to the active site of CDKs and blocking their activity, leading to cell cycle arrest and ultimately causing apoptosis. In addition, Bletilol B also inhibits the expression of proteins involved in cancer cell survival, making it an attractive candidate for future anticancer therapies.</p>

<p>3-Hydroxy mepivacaine is a drug product that is synthesized in the laboratory for research and development purposes. It has been shown to be metabolized by CYP2D6, CYP1A2, CYP3A4, CYP2C9 and CYP2C19. The metabolite of 3-hydroxy mepivacaine is not known at this time. 3-Hydroxy mepivacaine has been shown to have a potency of 1/10 of levobupivacaine, which is an analgesic drug used in clinical practice.</p>

<p>Please enquire for more information about 3-Des[2-(dimethylamino)ethyl] zolmitriptan acetonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Solifenacin Impurity D is a synthetic impurity of solifenacin. Solifenacin is an anti-cholinergic drug used to treat overactive bladder and urinary incontinence. The purity of this product is 99%. It is soluble in methanol, ethanol, chloroform, and acetone. Solifenacin Impurity D can be used as a reference material for analytical purposes or as an impurity standard in the development of new drugs.</p>

<p>4-(Phthalazin-1-yloxy)aniline is an analog of cyclin-dependent kinase (CDK) inhibitors that has shown promising anticancer activity. It inhibits the activity of CDKs, which are enzymes involved in regulating cell division and proliferation. This compound has been tested on Chinese hamster ovary cells and has demonstrated potent antiproliferative activity against various cancer cell lines. 4-(Phthalazin-1-yloxy)aniline induces apoptosis in tumor cells, leading to their death. This compound may be a potential candidate for the development of novel anticancer drugs that target CDKs and promote tumor cell death. Additionally, this compound can be detected in urine samples, making it a useful biomarker for cancer diagnosis and monitoring.</p>

<p>Risperidone pyrimidinone-N-oxide (ROPN) is a metabolite of risperidone. It is an impurity that is used as a reference standard for HPLC in the drug development process. ROPN can be synthesized from risperidone, but it is also found naturally in some plants and fungi. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>3-Carboxy-a-methyl-benzeneacetic acid (3CMA) is an impurity in the synthesis of 3,4-methylenedioxyphenylacetone. It is a preservative that has been analysed as a potential source of contamination in pharmaceutical preparations. 3CMA has been shown to be effective at inhibiting the growth of bacteria, yeast and moulds. The analysis time for 3CMA is typically 8 hours or less. The parameters that are used to analyse 3CMA include the use of acetonitrile, optimal porosity and efficiency. The analytical methods used for 3CMA include chromatographic and chromolith methods.</p>

<p>(S)-3''-Hydroxy pravastatin sodium salt is a drug product that is custom synthesized. It is the sodium salt of (S)-3''-hydroxypravastatin, which has been shown to be a natural product with high purity. The metabolite of (S)-3''-hydroxypravastatin sodium salt is 3'-hydroxypravastatin. This product can be used for analytical purposes as well as in pharmacopoeia, drug development, and research and development. It can also be used as an impurity standard for HPLC and GC analysis.</p>

<p>Lumiflavin 5-oxide is a metabolite of lumiflavin. It is a synthetic compound that is used as an analytical reference standard for impurities in lumiflavin and other pharmaceuticals. Lumiflavin 5-oxide has been shown to be metabolized through the cytochrome P450 system, with oxidative metabolites being formed by CYP1A2 and CYP3A4. Lumiflavin 5-oxide has also been shown to be a competitive inhibitor of NAD+-dependent enzymes such as glycerol kinase, phosphofructokinase, lactate dehydrogenase, alcohol dehydrogenase, and glucose 6-phosphate dehydrogenase.</p>

<p>Enantiomer of Perindopril t-Butylamine</p>

<p>Solifenacin is an anti-cholinergic drug that has been shown to have a potent antagonistic effect on muscarinic receptors. It is used in the treatment of overactive bladder, urinary incontinence, and irritable bowel syndrome. Solifenacin succinate is a metabolite of solifenacin and it has been found to be an antagonist of M3 muscarinic receptors. The presence of solifenacin and its metabolites in wastewater can interfere with treatment processes by inhibiting the removal of other organic chemicals such as tamsulosin hydrochloride. Optimisation studies for solifenacin production have shown that famotidine can be used as a process aid to reduce solifenacin impurities. Famotidine is also an antagonist of M3 muscarinic receptors and can be used to remove solifenacin from wastewater. Analytes detected in wastewater samples include solifenacin, famot</p>

<p>Please enquire for more information about Fenbufen-d9 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N2-Methyl alfuzosin hydrochloride (1:1) is a synthetic compound that is used as an impurity standard for the drug product Alfuzosin. It has been shown to be metabolized by the liver, and its metabolites are excreted through the bile. The N2-methyl group of this compound provides a marker for metabolism studies and it has been shown to inhibit bacterial growth in vitro.</p>

<p>Roxindole hydrochloride is a synthetic compound that is used to treat bowel disease. It belongs to the group of pharmaceutical preparations and has been shown to inhibit 5-HT1A receptors in the brain. Roxindole hydrochloride has been shown to have therapeutic effects on patients with ischemic brain damage, as well as dopamine-related diseases such as Parkinson's Disease and restless legs syndrome. This drug also inhibits the synthesis of proinflammatory cytokines in the gastrointestinal tract, which may be due to its ability to bind CB2 receptors.</p>

<p>22-Hydroxycholest-4-en-3-one is an analog that has been shown to have potent anticancer activity. It works by inhibiting kinase activity, which plays a key role in the regulation of cell cycle and apoptosis. This inhibitor has been found to induce apoptosis in cancer cells, leading to tumor regression. 22-Hydroxycholest-4-en-3-one has also been shown to inhibit protein synthesis and inhibit the growth of human cancer cell lines. In Chinese medicine, it is used for its medicinal properties and is present in urine as a natural metabolite. Its potential as an anticancer agent makes it a promising candidate for further research and development of cancer therapies.</p>

<p>Des(N-methyl-2-nitro-1,1-ethenediamino) N-methylureido nizatidine is a drug product that belongs to the group of ureidos. It has been used as an analytical standard for impurities in drugs and for HPLC standards. This compound has shown no toxicity in animal studies and is not metabolized by the human body. It does not bind to plasma proteins and is excreted unchanged in urine. The purity of this compound can be custom synthesized according to customer needs.</p>

<p>Atorvastatin is a drug product that is designed for the treatment of dyslipidemia, hypercholesterolemia, and mixed dyslipidemia. It is an impurity in the drug product Atorvastatin EP. Impurity B is a natural metabolite that has been found to have a niche market as an analytical standard for HPLC. The metabolite can be synthesized with high purity and quality standards, which are suitable for use in pharmacopoeia and research and development.</p>

<p>Please enquire for more information about 3-Desmethyl-3-(5-oxohexyl) pentoxifylline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Ethoxycarbonyl norfloxacin is a custom synthesis for research and development. It is an impurity standard used to determine the purity of drug product. This compound is synthesized using the chemistry of synthetic organic compounds, and it has a high purity. N-Ethoxycarbonyl norfloxacin can be used as a pharmacopoeia reference material or as a metabolite in metabolism studies.</p>

<p>(S)-2-Amino-3-(3,5-diiodo-4-(4-methoxyphenoxy)phenyl propanoic acid is a synthetic compound that is used as an impurity standard. It has been shown to be metabolized by cytochrome P450 enzyme system and its metabolites are excreted in the urine. This chemical can also act as an analytical reference for HPLC analysis of other compounds.</p>

<p>Remdesivir impurity 14 is a research and development product that belongs to the class of drugs. It is a synthetic metabolite with high purity. Remdesivir impurity 14 meets the pharmacopoeia standard for drug products and drug development. It has been synthesized to be used as an analytical standard for HPLC analysis of remdesivir. This product also has niche applications in metabolism studies, because it is a natural metabolite with its own metabolic pathway.</p>

<p>6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dimethyl-7H-purin-8(9H)-one is a drug product that belongs to the class of purine derivatives. The chemical name is 6-[(1-(2-fluorobenzyl)pyrazolo[3,4b]pyridin-3yl)amino]-2-(7,9dimethyl)-8(9H)purinone. It has been shown to be metabolized by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This active form is also bound to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX</p>

<p>7-Hydroxyhyoscyamine is an antibacterial agent that is used in the treatment of bacterial infections. It has been shown to inhibit the growth of a number of bacteria including Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli. 7-Hydroxyhyoscyamine has been shown to be more potent than 6-hydroxyhyoscyamine (6-OH Hya) for inhibiting protein synthesis in the bacteria. The compound does not have any psychoactive effects, unlike atropine sulfate, which is also an alkaloid found in plants from the Solanaceae family. 7-Hydroxyhyoscyamine can be synthesized by reacting atropine with nitrous acid or hydrochloric acid. This synthetic process leads to n-oxides as impurities, which can be removed by using a reversed phase high performance liquid chromatography (RP HPLC). Validation of this</p>

<p>Pyrazole N-demethyl sildenafil-d3 is a synthetic impurity standard for drug development and research. It is used as an analytical reference material for the study of metabolism in humans, animals, and other species. Pyrazole N-demethyl sildenafil-d3 has been shown to inhibit the CYP2C9 enzyme from metabolizing sildenafil, leading to increased plasma levels of active sildenafil.</p>

<p>Please enquire for more information about N-Demethyl-N-(ethylsuccinyl) erythromycin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-Chloro-N-[3-[[(5-chloro-2-thienyl)carbonyl]amino]-2-hydroxypropyl]-N-[4-(3-oxo-4-morpholinyl)phenyl]-2-thiophenecarboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N5-(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)-L-ornithine hydrochloride hydrate is a monoclonal antibody that is specific to lysine residues. It can be used in cancer tissue identification and detection of reactive cells. The formation rate of this antibody is dependent on the concentration of trifluoroacetic acid. N5-(5-Hydroxy-4,6-dimethyl-2-pyrimidinyl)-L-ornithine hydrochloride hydrate reacts with the amino group of lysine residues at pH 7.4 and has a logistic regression coefficient of 0.934 (95% confidence interval: 0.837 - 1.000). This antibody is also able to bind to pluripotent cells, which are cells capable of differentiating into any cell type, including neural cells in diabetic neuropathy patients and chaperones in biological samples.</p>

<p>Rotigotine Impurity 18 is a drug product that is an analytical standard for impurities. It is a synthetic impurity that is not found in natural sources. Rotigotine Impurity 18 has been used as a pharmacopoeia reference in the development of rotigotine, which is used to treat Parkinson's disease. This synthetic impurity has been extensively studied for its metabolism and toxicity properties.</p>

<p>N-Nitroso N-hydroxy cyclohexanamine is an analog of betamethasone and a potent inhibitor of kinases. It has been shown to have anticancer properties by inducing apoptosis in cancer cells. This compound is excreted in urine and has been studied extensively in Chinese populations for its potential as an anticancer agent. N-Nitroso N-hydroxy cyclohexanamine inhibits the activity of kinases, which are important enzymes involved in cell signaling pathways that regulate cell growth and division. This inhibition leads to the suppression of tumor growth and the induction of apoptosis in cancer cells. Additionally, this compound has been found to be a potent inhibitor of vitamin D receptor (VDR) and may play a role in regulating VDR-mediated gene expression.</p>

<p>Please enquire for more information about trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]cyclohexanol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>S 14506 Hydrochloride is a selective 5-HT1A receptor agonist that has been shown to have proapoptotic activity in prostate cancer cells. S 14506 Hydrochloride binds to the serotonin receptor, which is important for the modulation of mood, appetite, sexual function and pain sensation. It causes an increase in extracellular levels of hydrogen chloride and chloride ions, which may be responsible for its anxiolytic effects. This drug has also been shown to inhibit cell growth by binding to the subunits that make up the enzyme protein kinase A (PKA). PKA activates protein kinases, which are enzymes that regulate cellular processes such as metabolism and gene expression. In addition, S 14506 Hydrochloride binds to the 5-HT1A receptor on cancer cells and increases the synthesis of proteins associated with apoptosis or programmed cell death.</p>

<p>Lamivudine is an antiviral drug that belongs to the group of nucleoside analogues. It is a prodrug that is activated by intracellular phosphorylation to form the active compound, lamivudine triphosphate (L-TTP). L-TTP inhibits viral replication by competing with natural substrates for incorporation into viral DNA. The antiviral activity of L-TTP has been shown in animals and humans with hepatitis B virus or human immunodeficiency virus type 1 (HIV-1) infections. Lamivudine S-oxide is a stereoselective form of lamivudine, which can be used for chemoprophylaxis against the pandemic H1N1 virus. This drug has shown to have a lower toxicity profile than other drugs used for this purpose.</p>

<p>Please enquire for more information about Meropenem EP Impurity B Disodium Salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Acyclovir EP Impurity Q is a drug product that is used as the impurity standard for Acyclovir EP. It is a natural metabolite of acyclovir and may be found in the urine of patients taking this drug. Acyclovir EP Impurity Q has shown to have antiviral activity against herpes simplex virus type 1 and type 2. The structure of this compound has been determined by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.</p>

<p>Doxazosin-d8 hydrochloride is an analytical reference standard for HPLC and LCMS, and a drug development impurity. It is a metabolite of doxazosin that is used as an impurity in the manufacture of doxazosin. Doxazosin-d8 hydrochloride has been shown to be a substrate for CYP3A4, where it undergoes oxidation to form 2-(2-hydroxyphenyl)-N-[(1S)-1-[[(2R)-2-methylpropyl]sulfonyl]-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,6 dimethylphenyl)acetamide (CYP3A4). This metabolite may contribute to the pharmacological activity of doxazosin.</p>

<p>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol is a synthetic compound that is used as an intermediate in the synthesis of coumarin derivatives. Reaction with sulfonating agents produces sulfones, and reaction with borohydride reagents produces boronates. The synthesis of 2-methoxy-5-methyl-gamma-phenylbenzenepropanol can be accomplished by the reduction of diphenyl ethers with lithium aluminum hydride or borohydride. The reduction can also be carried out using lanthanum oxide and potassium borohydride. The reaction proceeds smoothly at room temperature in nonpolar solvents.<br>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol reacts with chloride to produce the corresponding chlorides, which are useful intermediates for the synthesis of tolterodine tartrate, a drug used to treat urinary inc</p>

<p>Please enquire for more information about Dutasteride EP impurity E including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>15-Epi travoprost is a synthetic, natural, and impurity standard drug product. It is used in research and development to study metabolism and pharmacology of drugs. 15-Epi travoprost is a metabolite of the drug product Prostaglandin F2α (PGF2α). The chemical name for this compound is 15-(3'-oxo-ethenyl)-prostaglandin F2α. This compound has been shown to be produced by the human body during metabolism of PGF2α. The CAS number for this compound is 1420791-14-5.</p>

<p>Chlorhexidine digluconate EP Impurity L is a metabolite of chlorhexidine digluconate. It is an impurity found in the drug product, which is used for the treatment of skin and mucous membrane infections. The mechanism of action for chlorhexidine digluconate EP Impurity L is not known. However, it has been shown to be metabolized by CYP3A4 and CYP2C9 enzymes to form chlorhexidine acetate, a metabolite that inhibits bacterial growth, and hydrolyzed by esterases to form 2-hydroxychlorhexidine acetate. This metabolite has been found in the urine of rats following oral administration with chlorhexidine digluconate EP Impurity L.</p>

<p>Dapoxetine N-oxide is a pharmaceutical agent that inhibits serotonin reuptake and has been shown to be effective in the treatment of premature ejaculation. It is a metabolite of dapoxetine, which is an antidepressant drug. Dapoxetine N-oxide has a terminal half-life of about 10 hours, which is shorter than that of its parent compound. Dapoxetine N-oxide also has a lower carcinogenic potential than its parent compound. This agent can inhibit the activity of rat liver microsomes, as well as human liver microsomes at high concentrations. It also has no effect on plasma concentrations at low doses, but does show dose proportionality at higher doses. Dapoxetine N-oxide also does not have any impurities or other drugs added to it.</p>

<p>2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene is an impurity found in sulfasalazine. It is a metabolite that is formed by the P450 system in the liver. The metabolic process of 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene has been studied in detail and has been shown to be a major contributor to the pharmacokinetic profile of sulfasalazine. This substance also exhibits antimicrobial activity and inhibits the growth of bacteria, fungi, and viruses.</p>

<p>N-(3-Trifluoromethylphenyl)-phenylamine is a research and development drug product that is used as an analytical impurity standard. It has a CAS number of 101-23-5 and is classified under the trade name 3TFPPA. The chemical formula for N-(3-Trifluoromethylphenyl)-phenylamine is C12H8F3NO. This compound can be synthesized from phenylamine, 3-trifluoromethylaniline, and hydrochloric acid. The molecular weight of this compound is 197.19 g/mol, which falls within the range of 195 to 200 g/mol. N-(3-Trifluoromethylphenyl)-phenylamine can be found in the following pharmacopoeia: USP (United States Pharmacopeia), EP (European Pharmacopoeia), JP (Japanese Pharmacopeia), BP</p>

<p>(2S, 4’R, 8’S)-α-Tocopherol is a vitamin E compound that has been shown to have various health benefits. It acts as an antioxidant and protects cells from oxidative damage. Additionally, it has been found to inhibit the growth of cancer cells by inducing apoptosis, inhibiting protein kinase C activity, and blocking the cell cycle. Studies have shown that (2S, 4’R, 8’S)-α-Tocopherol is a potent inhibitor of tumor growth in Chinese hamster ovary cells and human breast cancer cell lines. This vitamin has also been detected in urine samples of individuals who consume a diet rich in vitamin E. Overall, (2S, 4’R, 8’S)-α-Tocopherol is an important anticancer agent with promising therapeutic potential for cancer treatment.</p>

<p>Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate is an impurity that can be found in the drug product. It is a metabolite of clozapine, which is used to treat schizophrenia and other psychiatric disorders. This impurity can be detected by HPLC or LC/MS analysis and quantified using a calibration curve generated from standards. Methyl 4-methyl-3-[2-(propylamino)acetamido]thiophene-2-carboxylate may also be found in the urine as an indicator of clozapine use.</p>

<p>(4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone is a synthetic, impurity standard and research and development compound. (4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2pyrrolidinone is used as an analytical reference in the synthesis of other compounds. It is also used in drug development for the treatment of tuberculosis. This product has a high purity level and is pharmacopoeia grade.</p>

<p>DMAC-PDB is an aromatic cleavable linker commonly used in protein and drug conjugation. It enables controlled release of payloads under specific chemical conditions.</p>

<p>Diethyl 2-propylimidazole-4,5-dicarboxylate is a synthesized intermediate that can be used in the synthesis of other organic compounds. It is a diethyl ester of tartaric acid and an intermediate in the preparation of other organic compounds. The diethyl ester is made by nitrating diethyl to give diethyl nitrite, which is then reacted with tartaric acid to form the desired product. Diethyl 2-propylimidazole-4,5-dicarboxylate has been shown to be toxic, but it has not been shown to have any carcinogenic effects.</p>

<p>Olsalazine sodium impurity A is a synthetic drug that is used as an active pharmaceutical ingredient (API) in the development of drug products. It is a metabolite of olsalazine sodium, which is a natural product. Olsalazine sodium impurity A has been shown to be an analytical impurity for HPLC standards and is also used in metabolism studies. This impurity has niche applications as an analytical standard or as a pharmacopoeia reference material.END&gt;</p>

<p>Please enquire for more information about 6-(tert-Butylamino)-3-methyl-1,3,5-triazine-2,4(1H,3H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Monophenyl succinate is an organic compound that is a derivative of succinic acid. It contains a hydroxyl group, which reacts with hydrogen chloride to form a cross-linking agent. The diameters of the particles are between 1 and 100 nm. Monophenyl succinate can be used as a cross-linking agent in polymers and coatings, as well as an antihypertensive drug. The hydroxy group on the monophenyl group has ester linkages with the methyl and ethoxycarbonyl groups on the phenyl group. This compound also has methoxy groups and chlorine atoms attached to it. The reaction products of this compound are hydrogen chloride, hydroxyl group, and diameter.</p>

<p>4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide is a custom synthesis drug product. It is used as an analytical standard and has been shown to be metabolized in vitro. The main metabolites are 4'-hydroxymethyl-[1,1'-biphenyl]-2-carboxamide and 4'-carboxy-[1,1'-biphenyl]-2-carboxamide. The drug product is also a natural product and can be found in the human body.</p>

<p>Ulifloxacin acyl-β-D-glucuronide is an inhibitor of protein kinases that has been shown to induce apoptosis in cancer cells. This compound is a metabolite of ulifloxacin, a fluoroquinolone antibiotic used to treat urinary tract infections. Ulifloxacin acyl-β-D-glucuronide has potent anticancer activity and has been shown to inhibit the growth of tumor cells in vitro. This compound is an analog of other kinase inhibitors and has been extensively studied in Chinese hamster ovary (CHO) cells, where it was found to be effective against various types of cancer. Ulifloxacin acyl-β-D-glucuronide also possesses toxin-binding properties and may have potential as an anti-toxin agent.</p>

<p>Probimane is an anticancer drug that belongs to the class of kinase inhibitors. It is a synthetic analog of the Chinese herb, curcumol, and has been shown to inhibit the growth of tumor cells in vitro and in vivo. Probimane targets cyclin-dependent kinases (CDKs) and other protein kinases involved in cell cycle regulation, leading to apoptosis or programmed cell death. This drug has demonstrated potent activity against a range of human cancer cell lines, including breast, lung, and colon cancer. Probimane has also been found to be excreted in urine, making it a potential candidate for non-invasive monitoring of treatment efficacy.</p>

<p>Please enquire for more information about BCL6-IN-5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Adenosine cyclic 2',3'-phosphate 5'-phosphate is an inhibitor that has been shown to induce apoptosis in cancer cells. It is a urinary metabolite of nifedipine, an anti-hypertensive drug. Adenosine cyclic 2',3'-phosphate 5'-phosphate has anticancer activity and can inhibit protein kinase A, which plays a role in tumor growth and progression. This compound is an analog of cyclic adenosine monophosphate (cAMP) and can compete with cAMP for binding to regulatory subunits of protein kinases. Adenosine cyclic 2',3'-phosphate 5'-phosphate has been shown to inhibit the activity of several kinases, including protein kinase C, GSK-3β, and ERK1/2 in human cancer cells. It may have therapeutic potential as a targeted therapy for certain types of cancer.</p>

<p>N,N-Bis[2-(2-hydroxyethoxy)ethyl] quetiapine chloride is a synthetic drug product with a purity of &gt;98% and low impurity content, which is used in research and development. It can be custom synthesized to meet the needs of a particular research or development project. This compound has an analytical purity of &gt;98% and low impurity content, making it suitable for use as an API impurity standard. N,N-Bis[2-(2-hydroxyethoxy)ethyl] quetiapine chloride is not currently regulated by any pharmacopoeia.</p>

<p>O-De(3-fluorobenzyl) lapatinib ditosylate (OFLB) is a drug product that is supplied as a white to light yellow crystalline powder. It has been custom synthesized for the purpose of drug development and research. OFLB is an analytical standard and metabolite, which will be used in metabolism studies. This product is not intended for use in humans or animals.</p>

<p>Zanapezil is a human and Chinese analog of mirtazapine that has been studied for its potential anticancer properties. It is a protein kinase inhibitor that targets multiple kinases involved in cancer cell growth and survival, leading to induction of apoptosis (programmed cell death) in cancer cells. Zanapezil has been shown to be effective against various types of tumors, including lung cancer, breast cancer, and prostate cancer. It can be detected in urine after administration, making it a potential biomarker for monitoring treatment efficacy. With its promising anticancer activity and specificity as a kinase inhibitor, Zanapezil may offer new hope for cancer patients.</p>

<p>Please enquire for more information about Evixapodlin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Moclobemide N-oxide is a metabolite of moclobemide, an antidepressant drug. It is a white to off-white crystalline powder with a molecular formula of C14H14N2O4 and a molecular weight of 237.3. Moclobemide N-oxide is used in the treatment of depression, but it has not been approved for clinical use in the United States. Moclobemide N-oxide is extensively metabolized by cytochrome P450 enzymes, which may lead to variations in its activity among patients.</p>

<p>Please enquire for more information about 2-(Hydroxymethyl)-1-phenylcyclopropanecarbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rivaroxaban N-Hydrolyse N-5-Chlorothiophene-2-carbaldehyde is a drug product that is used as an analytical standard to study the metabolism of rivaroxaban. It is produced by custom synthesis and has been confirmed to be a high purity, pharmacopoeia grade material. This API impurity has CAS No. 1151893-81-0 and is classified as a natural material.</p>

Tivantinib is a potent inhibitor of the c-Met receptor tyrosine kinase, which plays a role in tumor growth and metastasis. This Chinese medicinal compound has been shown to have anticancer properties by inducing apoptosis in cancer cells and inhibiting cell cycle progression. Tivantinib has been found to be effective against a range of cancers, including leukemia and human solid tumors. In addition, this compound has been found in urine samples of cancer patients treated with tivantinib, indicating that it is excreted from the body after administration. Tivantinib is one of several protein kinase inhibitors currently being investigated for its potential as an anticancer therapy.

<p>2-tert-Butyl-1,2,3,4-tetrahydro-isoquinoline-4,6,8-triol is an impurity found in the drug product 2-tert-butyl-1,2,3,4-tetrahydroisoquinoline. It is a synthetic compound with pharmacological properties that have been studied in animals and humans. The chemical name for 2-tert-butyl isoquinoline is 4-(2'-methylpropoxy)-isoquinoline. The structure of this compound is shown below:</p>

<p>3,5-Dimethyl-2-(ethoxycarbonyl)-4-pyrone is a drug product that has been used as an HPLC standard. It has been used in the development of new drugs, and is a metabolite of many drugs including amoxicillin. 3,5-Dimethyl-2-(ethoxycarbonyl)-4-pyrone is also an impurity in some pharmaceuticals, such as the antibiotic cefazolin. This compound was synthesized for use as a research and development chemical. The synthesis of 3,5-dimethyl-2-(ethoxycarbonyl)-4-pyrone is based on the reaction between 2-chloroacetophenone and ethyl formate with potassium hydroxide. 3,5-dimethyl-2-(ethoxycarbonyl)-4-pyrone is an analytical standard for impurities in API compounds.</p>

<p>Propafenone beta-D-glucuronide is a drug product that is used as an analytical reference standard. It has been shown to be metabolized in the rat, dog, and human by hydrolysis of the glucuronide group. The natural form of propafenone is found in various plants and fruits. Research and Development includes the synthesis of Propafenone beta-D-glucuronide from synthetic precursors. CAS No. 91411-76-6 is a Metabolite impurity standard for API Impurities testing which is found in pharmaceuticals, including propafenone, as an impurity.</p>

<p>Aripiprazole EP Impurity E is a potential impurity of aripiprazole, which is an antipsychotic drug. It has been detected as a major impurity in the drug. Aripiprazole EP Impurity E has been found to be present in human plasma and it is thought that this impurity may have pharmacological effects on humans similar to those of aripiprazole. The detection of this impurity has been achieved using LC-MS/MS methods. This method can be used for wastewater treatment due to the matrix effect of nitrogen atoms. Aripiprazole EP Impurity E may have significant implications in the diagnosis, prevention, and treatment of obesity and other metabolic disorders.</p>

<p>N-Desmethyltoremifene is an anti-estrogen that has been shown to have genotoxic effects. It inhibits DNA synthesis and protein synthesis in human breast cancer cells. N-Desmethyltoremifene is a potent inducer of CYP3A4, which metabolizes many drugs. This drug also binds to α1-acid glycoprotein, which can lead to reduced plasma concentrations and pharmacokinetics. N-Desmethyltoremifene has been shown to inhibit the growth of renal cell carcinoma in animals, but not normal tissue, at high doses.</p>

<p>Simvastatin 4'-methyl ether is a metabolite of simvastatin. It is an impurity in the drug product and can be used as an analytical standard for HPLC. It is not a drug product or a pharmaceutical ingredient, but it can serve as an impurity standard for pharmacopoeia.</p>

<p>Dahurinol is an analog of teriparatide and a potent inhibitor of replication kinase. This compound has been shown to induce apoptosis in human cancer cells through the inhibition of trypsin-like proteasome activity. Dahurinol has been found to be effective against a variety of cancers, including breast, lung, and colon tumors. In addition, it has been shown to enhance the efficacy of methotrexate in cancer treatment. This compound also exhibits antioxidant properties due to its similarity to astaxanthin, which may contribute to its anti-cancer effects. Dahurinol is commonly used in traditional Chinese medicine for its medicinal properties, and its potential as an anti-cancer agent makes it a promising area for further research.</p>

<p>(R)-Valiolamine voglibose dihydrochloride is an analog of voglibose that acts as a potent inhibitor of alpha-glucosidases. It has been shown to be effective in reducing blood glucose levels in humans and has also been investigated as a potential anticancer agent. (R)-Valiolamine voglibose dihydrochloride inhibits the activity of kinases, which are enzymes that play a critical role in cancer cell growth and survival. This inhibition leads to the induction of apoptosis and the suppression of tumor growth. Additionally, this drug has been found to increase the levels of glutathione, which is an antioxidant that protects cells from oxidative stress. (R)-Valiolamine voglibose dihydrochloride has shown promising results in preclinical studies for various types of cancer, including breast, lung, and pancreatic cancers. It has also been evaluated as a potential inhibitor for rivaroxaban and ginsenoside.</p>

<p>Meclofenamate sodium hydrate is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase, lipoxygenase, and phospholipase A 2 . It has been shown to be effective in the treatment of many diseases such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and gout. Meclofenamate sodium hydrate is a potent inducer of polymorphonuclear leucocytes, which are cells involved in the inflammatory response. It also reduces the production of prostaglandins and leukotrienes by inhibiting cyclooxygenase and lipoxygenase enzymes. This agent is very potent in inhibiting diphosphatidylinositol 4-kinase (DPP IV), which is involved in the degradation of glucocorticoids.</p>

<p>2-Aminoethyl-amino palbociclib is a versatile compound used in various industrial applications. It is commonly used in the production of cellulose, where it acts as a basic protein to enhance the efficiency of cellulose synthesis. Additionally, 2-Aminoethyl-amino palbociclib is also utilized in the extraction of chamomile extract, as it helps to preserve the active compounds and growth factors present in the extract.</p>

<p>Please enquire for more information about (S)-Carisbamate β-D-o-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Demethoxy-4-methoxy urapidil is a drug product that is used in the development of new drugs. It is a synthetic compound that is metabolized to form its natural metabolite, 2-demethoxyurapidil. This impurity standard has been shown to have anti-inflammatory effects and can be used as an API impurity for pharmacopoeia. 2DMO4MU has been shown to be useful in the study of metabolism and has been found to inhibit prostaglandin synthesis.</p>

<p>8-Hydroxy warfarin-d5 is a drug product that is an impurity standard for the metabolism of warfarin. It is an analytical standard that can be used to determine the concentration of warfarin in a sample. The CAS number for 8-Hydroxy warfarin-d5 is 94820-66-3, and it has a molecular weight of 318.83 g/mol. This compound can be synthesized from natural sources or by chemical synthesis. 8-Hydroxy warfarin-d5 may also be used as a research and development tool in pharmacology, drug development, and toxicology studies.</p>

<p>Please enquire for more information about 7,8,9,10-Dehydro doxorubicinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>