APIs for research and impurities
Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,333 products)
- Anthraquinones and derivatives(404 products)
- Benzimidazole and Imidazole Derivatives(10,446 products)
- Benzodiazepine Derivatives(334 products)
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- Esters and Derivatives(42,250 products)
- Fatty Acids and Lypidic Derivatives(32,413 products)
- Flavonoids and Polyphenols(17,083 products)
- Free Radicals and Oxidant/Reducing Agents(213 products)
- Ketones and derivatives(2,401 products)
- Natural and semi-synthetic antibiotics(6,382 products)
- Nitriles and Cyano Derivatives(3,068 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,480 products)
- Organic Phosphates and Phosphonates(1,201 products)
- Organic Sulphonates and Sulphates(10,433 products)
- Organometallics(4,421 products)
- Others(6,305 products)
- Peptides and Proteins(3,148 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,948 products)
- Quinazoline and Quinoline Derivatives(66,025 products)
- Quinones and Derivatives(24,362 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(80,543 products)
- Steroids and Derivatives(4,954 products)
- Sulfonamides and Derivatives(2,595 products)
- Terpenoids and Derivatives(3,848 products)
- Thiazolidinediones and Thiopyrans(2,753 products)
- β-Adrenergic Compounds(231 products)
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Found 57820 products of "APIs for research and impurities"
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Vortioxetine Impurity 19
CAS:3-Indoxyl β-D-galactopyranoside, 6-fluoro-3-indoxyl β-D-galactopyranoside, Tilmicosin, 3-Desacetylcefotaxime potassium, Gatifloxacin, Vortioxetine Impurity 19Formula:C18H22N2OSPurity:Min. 95%Molecular weight:314.4 g/mol4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(trityltetrazol-5-yl)phenyl]phenyl]methylimidazo-5-carboxylate (5-methyl-2-oxo-1,3-dioxo len-4-yl)methyl
CAS:5-methyl-2-oxo-1,3-dioxo-4-[(4-[2-(trityl)phenyl]phenyl)methylimidazo]-5-carboxylate is a drug that belongs to the group of angiotensin II receptor antagonists. The main human metabolite is the product of N-dealkylation at the nitrogen atom of the imidazole ring. It has been shown to inhibit rat liver microsomes at concentrations of 2.5 and 5 μM. This compound is also found as an impurity in cilexetil and olmesartan, which are other drugs belonging to this class. Impurities can be detected by using metal hydroxides, amines and biphenyl as reagents, or with gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS), or high performance liquid chromatography/massFormula:C48H44N6O6Purity:Min. 95%Color and Shape:SolidMolecular weight:800.9 g/molEmtricitabine carboxylic acid
CAS:Emtricitabine (FTC) is a synthetic nucleoside analog that is approved for the treatment of HIV infection. FTC is metabolized in the liver by cytochrome P450 enzymes into two metabolites, EMTR-diol and EMTR-triol. The pharmacopoeia defines impurity standards for both metabolites. FTC also causes metabolism studies to be conducted to determine its effect on other drugs such as cyclosporin and phenytoin. EMTR-diol: CAS No. 1238210-10-0 EMTR-triol: CAS No. 1238210-11-1Formula:C8H8FN3O4SPurity:Min. 95%Molecular weight:261.23 g/molAmlodipine EP Impurity E maleate
CAS:Amlodipine EP Impurity E maleate is a high purity and analytical grade chemical. It is a metabolite of Amlodipine, which is used in the treatment of hypertension. This chemical has been shown to be a natural product that is produced by the human body. It also has been shown to have pharmacological properties, such as anti-inflammatory and vasodilatory effects. The impurity standard for this compound is available from Sigma-Aldrich.br>br>
Formula:C21H27ClN2O5•C4H4O4Purity:Min. 95%Molecular weight:538.98 g/mol7-Epi 10-desacetyl paclitaxel
CAS:7-Epi 10-desacetyl paclitaxel is a prodrug of paclitaxel. It has a similar mechanism of action to paclitaxel, and is used as a chemotherapeutic agent for the treatment of cancer. 7-Epi 10-desacetyl paclitaxel has shown potent apoptotic activity in cell culture, as well as in animal models. This drug is prepared by high performance liquid chromatography and is used to treat cancer. The drug may also be activated by an enzyme called adenosine diphosphate ribose (ADPR), which forms from ATP during cellular metabolism. 7-Epi 10-desacetyl paclitaxel may also have anticancer effects on cervical cancer cells due to its ability to inhibit the synthesis of DNA and RNA.Formula:C45H49NO13Purity:Min. 95%Color and Shape:White PowderMolecular weight:811.87 g/molAtorvastatin lactam phenanthrene calcium salt impurity
CAS:Atorvastatin lactam phenanthrene calcium salt impurity is a high purity, custom synthesis drug product. It is a metabolite of atorvastatin and was identified using metabolism studies in rat and human liver microsomes. This impurity has been shown to be an analytical standard for HPLC. Atorvastatin lactam phenanthrene calcium salt impurity is used in niche research and development, as well as the development of drugs that are pharmacopoeia grade.
Formula:C66H64CaF2N4O12Purity:Min. 95%Molecular weight:1,183.31 g/mol1-Fluoronaphthalene
CAS:1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.
Formula:C10H7FPurity:Min. 95%Molecular weight:146.16 g/molN-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.Formula:C12H9F3N2O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:270.21 g/molPitavastatin N-oxide
CAS:Pitavastatin N-oxide is a drug product that is an analytical standard and natural API impurity. It is used in the synthesis of other drugs, such as pitavastatin, which is a statin drug used to lower cholesterol levels. Pitavastatin N-oxide has been shown to be a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate. This inhibits cholesterol production and lowers levels of low density lipoprotein (LDL) cholesterol in the blood.Formula:C25H24FNO5Purity:Min. 95%Molecular weight:437.46 g/molVildagliptin nitrosamine impurity 1
CAS:Please enquire for more information about Vildagliptin nitrosamine impurity 1 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C17H24N4O3Molecular weight:332.4 g/molClopidogrel EP Impurity B hydrochloride
CAS:Please enquire for more information about Clopidogrel EP Impurity B hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C16H16ClNO2S•HClPurity:Min. 95%Molecular weight:358.28 g/molVildagliptin Related Compound 2
CAS:Vildagliptin Related Compound 2 is a synthetic compound that has been shown to be an inhibitor of DPP-4. It is a white solid that can be synthesized by condensation of vildagliptin with chloroacetyl chloride in the presence of an alkali. The compound was found to have impurities, including 1-(2-chlorophenyl)ethanol and 3-chlorobenzaldehyde.Formula:C17H25N3O2Purity:Min. 95%Molecular weight:303.4 g/molCinacalcet Impurity B HCl
CAS:Cinacalcet Impurity B HCl is an analytical standard that can be used in HPLC as a reference compound. It is also a metabolite of Cinacalcet and has been shown to have affinity for calcium channels. This impurity is found in Cinacalcet at a concentration of less than 1%.Formula:C19H20NClPurity:Min. 95%Color and Shape:PowderMolecular weight:297.82 g/mol3β-Hydroxy pravastatin lactone
CAS:3Beta-Hydroxy pravastatin lactone is a synthetic compound that is the primary metabolite of pravastatin. It has been shown to decrease cholesterol levels in the blood and to be an analytical standard for HPLC. 3Beta-Hydroxy pravastatin lactone has also been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.Formula:C23H34O6Purity:Min. 95%Molecular weight:406.50 g/molDescarboxyl febuxostat
CAS:Descarboxyl febuxostat is a synthetic drug that is metabolized to its active form, febuxostat. This drug product has been custom synthesized and is of high purity. Descarboxyl febuxostat has been used in the development of drugs for hypertension, hypercholesterolemia, and gout. It has also been used as a research tool for studying the metabolism of drugs in humans.Formula:C15H16N2OSPurity:Min. 95%Molecular weight:272.40 g/mol2'-Hydroxy-3-phenylpropiophenone
CAS:2'-Hydroxy-3-phenylpropiophenone is a nucleophile that is hydrogenated to form 2'-hydroxy-3-phenylpropionic acid. It is used as a precursor for the synthesis of chalcones, which are biotransformed by microorganisms to form enantiomers and dihydrochalcones. This substance also has pharmacological activity and multidrug resistance. It is used as a sweetener in foods and beverages.Formula:C15H14O2Purity:Min. 95%Color and Shape:Colourless To Pale Yellow LiquidMolecular weight:226.27 g/molMitoxantrone (2-hydroxyethyl)piperazine impurity
CAS:Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.Formula:C22H26N4O6Purity:Min. 95%Color and Shape:Brown PowderMolecular weight:442.47 g/molRosuvastatin EP impurity M calcium
CAS:Please enquire for more information about Rosuvastatin EP impurity M calcium including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:(C22H29N3O6S)2•CaPurity:Min. 95%Molecular weight:967.1 g/mol(2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic acid
CAS:Orlistat is a lipase inhibitor that is used as a weight-loss drug. It works by inhibiting the absorption of dietary fats and their subsequent conversion into triglycerides in the intestines, thereby limiting the calories absorbed. Orlistat has been shown to be effective in lymphatic and fatty acid transport, but oral bioavailability is low due to extensive first-pass metabolism. Orlistat inhibits pancreatic lipase, which may lead to reduced intestinal fat absorption and decreased systemic exposure. This drug also inhibits long-chain fatty acids from being absorbed through the intestinal wall and prevents them from being metabolized, thereby reducing lipid formulations in the blood.Formula:C29H55NO6Purity:Min. 95%Molecular weight:513.75 g/molApixaban Impurity 6
CAS:Please enquire for more information about Apixaban Impurity 6 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C26H26N4O5Purity:Min. 95%Molecular weight:474.51 g/mol
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