Peptides

Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.

<p>Applications L-Carnosine is a naturally-occurring histidine-containing compound and the biological role of this dipeptide is to act as cytosolic buffering agents. Other roles ascribed to L-Carnosine include actions as neurotransmitters, modulation of enzymic activities and chelation of heavy metals.<br>References Quinn, P.J., et al.: Mol. Aspects. Med., 13, 379 (1992); Aruoma, O.I., et al.: Biochem. J., 264, 863 (1989);<br></p>

Fmoc-His-OH (FMOC-L-Histidine) is a histidine derivative and a common material for peptide synthesis.

<p>Applications Lactoferrin is a multifunctional protein of transferin family. A glycoprotein present in various secretions including milk, saliva and tears. Antiviral agent, it binds to liproproteins of cell membranes dispersing virus molecules from host cells.<br>References Sánchez L. et al.: Arch. Dis. CHild., 67, 657 (1992); Harmsen MC. et al.: J. Infect. Dis., 172, 380 (1995);<br></p>

Nisin A: a lantibiotic peptide made by L. lactis, contains unique amino acids like lanthionine, and fights bacteria.

<p>Applications Glutamine analog.<br>References Hellberg, S., et al.: J. Med. Chem., 30, 1126 (1987), Blondelle, S., et al.: Antimicrob. Agents Chemother., 38, 2280 (1994), Jiracek, J., et al.: J. Biol. Chem., 270, 21701(1995),<br></p>

H-Leu-Leu-OMe HBr (L-Leucyl-L-Leucine methyl ester HBr) is a dipeptide condensation of L-Leucine methyl ester, a peptide that is toxic to natural killer T-cells

<p>Stability Hygroscopic<br>Applications H-Asp-Leu-OH (cas# 3062-14-4) is a useful research chemical.<br></p>

<p>Applications tert-Butoxycarbonyl-D-proline is Boc protected D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.<br>References Jung, M., et al.: Bioorg. Med. Chem. Lett., 7, 1655 (1997); Lee, D., et al.: J. Med. Chem,, 44, 2015 (2001)<br></p>

<p>Stability Hygroscopic<br>Applications This compound is an impurity in the synthesis of Antazoline (A678405) which acts as a histamine H1 receptor blocker, functioning as an antihistamine pharmaceutical.<br>References Constanti, A. et al.: Brit. J. Pharmacol. 58, 583 (1976);<br></p>

<p>Applications Benzotriazol-1-yl-oxytripyrrolidinphosphonium Hexafluorophosphate (cas# 128625-52-5) is a compound useful in organic synthesis.<br></p>

<p>Applications n-Octyl-oligo-oxyethylene is a detergent for useful solubilization, purification and crystallization of proteins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic<br>Applications MG 132 is a potent, membrane-permeable proteasome inhibitor. It induces neurite outgrowth in PC12 cells. Neuroprotective product.<br>References Lee, D., et al.: Trends in Cell Biol., 8, 397 (1998); Tsubuki, S., et al.: J. Biochem., 119., 572 (1996); Grimm, L., et al.: EMBO J., 15, 3835 (1996)<br></p>

<p>Applications Z-VAL-MET-OH (cas# 108543-82-4) is a useful research chemical.<br></p>

<p>Applications N-tert-Boc-L-alanine is the protected form of L-Alanine (A481500), a non-essential amino acid that can be found naturally in the human body and is obtained by our diet.<br>References Anderson, H., et al.: J. Nutr., 99, 82 (1969)<br></p>

<p>Stability Hygroscopic<br>Applications H-ALA-ASP-OH (cas# 20727-65-5) is a useful research chemical.<br></p>

<p>Applications Poly(ethylene Glycol) molecules of an average molecular mass of 200. Poly(ethylene Glycol) is used in various applications from industrial chemistry to biological chemistry. Recent research has shown PEG maintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals. In rats, it has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery. It is industrially produced as a lubricating substance for various surfaces to reduce friction. PEG is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.<br>References Borgens, R. et al.: J. Neurosci. Res., 66, 1179 (2001); Stavisky, R. et al.: Neurosci. Lett., 376, 98 (2005); Nalam, P. et al.: Tribiol. Lett., 37, 541 (2010); Steinmetz, N. et al.: J. Am. Chem. Soc., 131, 17093 (2009); Li, X. et al.: J. Am. Chem. Soc., 133, 11147 (2011); Li, L. et al.: Int. J. Pharm., 447, 192 (2013);<br></p>