Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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PD 407824
CAS:<p>PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).</p>Fórmula:C20H12N2O3Pureza:98.02%Forma y color:SolidPeso molecular:328.322'-O-Methyl-5-iodouridine
CAS:<p>2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a</p>Fórmula:C10H13IN2O6Pureza:99.89%Forma y color:SolidPeso molecular:384.12TG003
CAS:<p>TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.</p>Fórmula:C13H15NO2SPureza:99.46%Forma y color:SolidPeso molecular:249.33Talotrexin
CAS:<p>Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.</p>Fórmula:C27H27N9O6Forma y color:SolidPeso molecular:573.56kb-NB77-78
CAS:<p>kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).</p>Fórmula:C18H25NO3SiPureza:99.54%Forma y color:SolidPeso molecular:331.48Rabusertib
CAS:<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Fórmula:C18H22BrN5O3Pureza:98.86% - 99.87%Forma y color:SolidPeso molecular:436.3Trilaciclib
CAS:<p>Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.</p>Fórmula:C24H30N8OPureza:99.624%Forma y color:SolidPeso molecular:446.55Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Forma y color:SolidPeso molecular:516.65Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Fórmula:C26H32ClN7O4SForma y color:SolidPeso molecular:574.09NSC 617145
CAS:<p>NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent</p>Fórmula:C13H10Cl4N2O4Pureza:99.72%Forma y color:SolidPeso molecular:400.04GDC0575 monohydrochloride
CAS:<p>GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.</p>Fórmula:C16H21BrClN5OPureza:97.85%Forma y color:SolidPeso molecular:414.73AT-9283 HCl
CAS:<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Fórmula:C19H24ClN7O2Forma y color:SolidPeso molecular:417.89Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Fórmula:C26H26N3NaO5SForma y color:SolidPeso molecular:515.56Phosphonoformic acid trisodium salt hexa
CAS:<p>Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.</p>Fórmula:CH12Na3O11PPureza:98%Forma y color:SolidPeso molecular:300.03E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Forma y color:SolidPeso molecular:336.37EN4
CAS:<p>EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.</p>Fórmula:C25H24N2O4Pureza:98.51%Forma y color:SolidPeso molecular:416.47CKI-7 free base
CAS:<p>CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Fórmula:C11H12ClN3O2SForma y color:SolidPeso molecular:285.75MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Fórmula:C15H9NO3Pureza:98.6%Forma y color:SolidPeso molecular:251.24TH-263
CAS:<p>TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.</p>Fórmula:C21H20N2O3SPureza:99.54%Forma y color:SolidPeso molecular:380.46iRGD peptide
CAS:<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Fórmula:C35H57N13O14S2Pureza:98.77%Forma y color:SolidPeso molecular:948.04Orbofiban
CAS:<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Fórmula:C17H23N5O4Forma y color:SolidPeso molecular:361.4APTO-253 HCl
CAS:<p>APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.</p>Fórmula:C22H15ClFN5Forma y color:SolidPeso molecular:403.84HA-100 hydrochloride
CAS:<p>HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.</p>Fórmula:C13H16ClN3O2SForma y color:SolidPeso molecular:313.8BMH-21
CAS:<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Forma y color:SolidPeso molecular:360.41S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Fórmula:C22H21NO2SPureza:97.02%Forma y color:Almost White To Light Yellow Granular PowderPeso molecular:363.47Apcin
CAS:<p>Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.</p>Fórmula:C13H14Cl3N7O4Pureza:96.74%Forma y color:SolidPeso molecular:438.65CHR-6494
CAS:<p>CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).</p>Fórmula:C16H16N6Pureza:98.78%Forma y color:SolidPeso molecular:292.34Palmatine chloride
CAS:<p>Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.</p>Fórmula:C21H22ClNO4Pureza:97.9% - 99.47%Forma y color:SolidPeso molecular:387.857Datelliptium chloride hydrochloride
CAS:<p>Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.</p>Fórmula:C23H29Cl2N3OPureza:99.46%Forma y color:SolidPeso molecular:434.4CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Forma y color:SolidPeso molecular:551.48AZD-7762
CAS:<p>AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.</p>Fórmula:C17H19FN4O2SPureza:98.96% - 99.19%Forma y color:SolidPeso molecular:362.42Netarsudil free base
CAS:<p>Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.</p>Fórmula:C28H27N3O3Forma y color:SolidPeso molecular:453.53NG 52
CAS:<p>NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.</p>Fórmula:C16H19ClN6OPureza:98% - 99.34%Forma y color:SolidPeso molecular:346.81LY3143921
CAS:<p>LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].</p>Fórmula:C16H12FN5OForma y color:SolidPeso molecular:309.3RCM-1
CAS:<p>RCM-1 is an inhibitor of FOXM1.</p>Fórmula:C20H12N2OS4Pureza:98.08%Forma y color:SolidPeso molecular:424.58IRE1α kinase-IN-1
CAS:<p>IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.</p>Fórmula:C26H26ClFN8Pureza:99.18%Forma y color:SolidPeso molecular:504.99Levomefolate calcium
CAS:<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Fórmula:C20H23CaN7O6Pureza:97.35%Forma y color:Off-White To Pale Yellow SolidPeso molecular:497.52Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Fórmula:C28H26Cl2N4O5Pureza:99.26% - 99.72%Forma y color:SolidPeso molecular:569.44Brr2-IN-3
CAS:<p>Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.</p>Fórmula:C24H20N4O3SPureza:99.26%Forma y color:SolidPeso molecular:444.51Avotaciclib trihydrochloride
CAS:<p>Avotaciclib trihydrochloride (BEY1107) is an oral CDK1 inhibitor targeting advanced pancreatic cancer.</p>Fórmula:C13H14Cl3N7OPureza:99%Forma y color:SolidPeso molecular:390.653'-Deoxyguanosine
CAS:<p>3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.</p>Fórmula:C10H13N5O4Pureza:98.85% - 98.96%Forma y color:SolidPeso molecular:267.24Tempo
CAS:<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Fórmula:C9H18NOPureza:98.35%Forma y color:Orange Crystals Or PowderPeso molecular:156.25AI-10-49
CAS:<p>AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.</p>Fórmula:C30H22F6N6O5Pureza:97.14%Forma y color:SolidPeso molecular:660.526-Thioinosine
CAS:<p>6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.</p>Fórmula:C10H12N4O4SPureza:97.74%Forma y color:SolidPeso molecular:284.29Deoxythymidine triphosphate
CAS:<p>Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.</p>Fórmula:C10H14N2Na3O14P3Pureza:99.78%Forma y color:White Amorphous PowderPeso molecular:548.11PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Fórmula:C18H21Cl3N4OPureza:99.5%Forma y color:SolidPeso molecular:415.75Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Forma y color:SolidPeso molecular:375.37Pyridostatin hydrochloride
CAS:<p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>Fórmula:C31H37Cl5N8O5Forma y color:SolidPeso molecular:778.94BMS-8
CAS:<p>BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.</p>Fórmula:C27H28BrNO3Pureza:98.88%Forma y color:SolidPeso molecular:494.42Mps1-IN-1 dihydrochloride
CAS:<p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>Fórmula:C28H35Cl2N5O4SForma y color:SolidPeso molecular:608.58UNC10217938A
CAS:<p>UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects.</p>Fórmula:C26H28N6O2Pureza:98%Forma y color:SolidPeso molecular:456.54LY3405105
CAS:<p>LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-</p>Fórmula:C26H39N7O3Pureza:99.66%Forma y color:SolidPeso molecular:497.63Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Fórmula:C26H30FN7O3Pureza:98.43% - 99.29%Forma y color:SolidPeso molecular:507.56N6,N6-Dimethyladenosine
CAS:<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Fórmula:C12H17N5O4Pureza:98.79%Forma y color:White PowderPeso molecular:295.29Proguanil
CAS:<p>Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .</p>Fórmula:C11H16ClN5Pureza:99.6%Forma y color:SolidPeso molecular:253.73FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Fórmula:C17H18FN3SPureza:98.61%Forma y color:SolidPeso molecular:315.41NVP-LCQ195
CAS:<p>NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).</p>Fórmula:C17H19Cl2N5O4SPureza:99.56% - 99.85%Forma y color:SolidPeso molecular:460.33JSH-150
CAS:<p>JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).</p>Fórmula:C24H33ClN6O2SPureza:99.96% - 99.96%Forma y color:SolidPeso molecular:505.08Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Fórmula:C27H40N8O7Pureza:98% - 99.8%Forma y color:SolidPeso molecular:588.66Atuveciclib
CAS:<p>Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.</p>Fórmula:C18H18FN5O2SPureza:98.8%Forma y color:SolidPeso molecular:387.432-Chloroadenosine
CAS:<p>2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively</p>Fórmula:C10H12ClN5O4Pureza:99.23%Forma y color:White PowderPeso molecular:301.69Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Fórmula:C29H29FN3O9PPureza:95.87%Forma y color:SolidPeso molecular:613.53GSK461364
CAS:<p>GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.</p>Fórmula:C27H28F3N5O2SPureza:99% - 99.73%Forma y color:SolidPeso molecular:543.6ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Forma y color:SolidPeso molecular:533.593-AP
CAS:<p>3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).</p>Fórmula:C7H9N5SPureza:97.33% - 99.87%Forma y color:SolidPeso molecular:195.24CW-069
CAS:<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Forma y color:SolidPeso molecular:500.33CCG-203971
CAS:<p>CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.</p>Fórmula:C23H21ClN2O3Pureza:98.82% - 99.50%Forma y color:SolidPeso molecular:408.88SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Fórmula:C25H20FN7OPureza:97.82%Forma y color:SolidPeso molecular:453.47LY2880070
CAS:<p>LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.</p>Fórmula:C19H23N7O2Pureza:99.77%Forma y color:SolidPeso molecular:381.43BMS-1001
CAS:<p>BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).</p>Fórmula:C35H34N2O7Pureza:98.43%Forma y color:SolidPeso molecular:594.7WNK-IN-11
CAS:<p>WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)</p>Fórmula:C21H21Cl2N5OSPureza:98.32%Forma y color:SolidPeso molecular:462.4Bractoppin
CAS:<p>Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits</p>Fórmula:C25H23FN4OPureza:98.38%Forma y color:SolidPeso molecular:414.47DMT-2′Fluoro-dU Phosphoramidite
CAS:<p>DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.</p>Fórmula:C39H46FN4O8PPureza:99.5%Forma y color:SolidPeso molecular:748.78BMS-5
CAS:<p>BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.</p>Fórmula:C17H14Cl2F2N4OSPureza:98.01% - 99.88%Forma y color:SolidPeso molecular:431.292′-Deoxy-2′-fluoroguanosine
CAS:<p>2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).</p>Fórmula:C10H12FN5O4Pureza:99.89%Forma y color:SolidPeso molecular:285.23AZD-5597
CAS:<p>AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent</p>Fórmula:C23H28FN7OPureza:98.01%Forma y color:SolidPeso molecular:437.51WR99210 hydrochloride(47326-86-3 free base)
CAS:<p>WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.</p>Fórmula:C14H19Cl4N5O2Pureza:97.77% - 99.8%Forma y color:SolidPeso molecular:431.14Saccharin 1-methylimidazole
CAS:<p>Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.</p>Fórmula:C7H5NO3S·C4H6N2Pureza:98.21%Forma y color:SolidPeso molecular:265.29LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Fórmula:C23H29ClN8OPureza:100%Forma y color:SolidPeso molecular:469.02Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Forma y color:SolidPeso molecular:517.06Bonafton
CAS:<p>Bonafton (Bonaphthone) is an antiviral agent.</p>Fórmula:C10H5BrO2Pureza:97.16%Forma y color:SolidPeso molecular:237.053-Deazauridine
CAS:<p>3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.</p>Fórmula:C10H13NO6Pureza:99.86%Forma y color:SolidPeso molecular:243.21Calcium N5-methyltetrahydrofolate
CAS:<p>Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and</p>Fórmula:C20H23CaN7O6Pureza:99.41%Forma y color:SolidPeso molecular:497.51CC-671
CAS:<p>CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.</p>Fórmula:C28H28N6O4Pureza:98.66% - 98.8%Forma y color:SolidPeso molecular:512.56Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Fórmula:C14H23F3N6O8Pureza:99.2% - ≥98%Forma y color:SolidPeso molecular:460.36Trifluridine/tipiracil hydrochloride mixture
CAS:<p>Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a</p>Fórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Forma y color:SolidPeso molecular:871.53Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Forma y color:SolidPeso molecular:355.36EHT 1864 2HCl
CAS:<p>EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.</p>Fórmula:C25H29Cl2F3N2O4SPureza:98.39% - 99.42%Forma y color:SolidPeso molecular:581.47Danofloxacin
CAS:<p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>Fórmula:C19H20FN3O3Pureza:99.77% - 99.8%Forma y color:SolidPeso molecular:357.38GPRP acetate (67869-62-9 free base)
CAS:<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Fórmula:C20H35N7O7Pureza:>99.99%Forma y color:SolidPeso molecular:485.536-O-Methyl Guanosine
CAS:<p>6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.</p>Fórmula:C11H15N5O5Pureza:97.5%Forma y color:SolidPeso molecular:297.27MLN0905
CAS:<p>MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).</p>Fórmula:C24H25F3N6SPureza:97.17% - 98%Forma y color:SolidPeso molecular:486.56Levoleucovorin Calcium
CAS:<p>Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.</p>Fórmula:C20H21N7O7·CaPureza:99.07% - ≥98%Forma y color:White Crystalline PowderPeso molecular:511.5BMS-3
CAS:<p>BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.</p>Fórmula:C17H12Cl2F2N4OSPureza:99.31% - 99.81%Forma y color:SolidPeso molecular:429.27Fanotaprim
CAS:<p>Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.</p>Fórmula:C19H22N8OPureza:98.1%Forma y color:SolidPeso molecular:378.43TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Fórmula:C24H21Cl2NO5Pureza:98.98%Forma y color:SolidPeso molecular:474.33EOAI3402143
CAS:<p>EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.</p>Fórmula:C25H28Cl2N4O3Pureza:99.6%Forma y color:SolidPeso molecular:503.42LY3177833
CAS:<p>LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)</p>Fórmula:C16H12FN5OPureza:99.87%Forma y color:SolidPeso molecular:309.3LXW7
CAS:<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Fórmula:C29H48N12O12S2Pureza:>99.99%Forma y color:SolidPeso molecular:820.89AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:381.43
