Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(116 productos)
- CDK(547 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(46 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(276 productos)
- Kinesina(87 productos)
- LIM quinasa(21 productos)
- Asociado a microtúbulos(273 productos)
- PKC(127 productos)
- PLK(25 productos)
- ROCK(61 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(77 productos)
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Se han encontrado 3923 productos de "Ciclo celular / Checkpoint"
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4-Amino-5-cyano-1-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine
CAS:Nucleoside Derivatives - 7-Deaza-purine nucleosides; Scaffolds and TemplatesFórmula:C12H13N5O4Forma y color:SolidPeso molecular:291.26Ref: TM-TNU0271
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar4-Deoxy-xylo-uridine
CAS:Nucleoside Derivatives - Xylo-nucleosides; 4-Deoxy pyrimidine nucleosidesFórmula:C9H12N2O5Forma y color:SolidPeso molecular:228.2Ref: TM-TNU1366
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-2'-fluoro-3',5'-bis-O-TBDMS-uridine
CAS:Nucleoside Derivatives –Fluoro-modified nucleosides；Fórmula:C21H39FN2O5Si2Forma y color:SolidPeso molecular:474.71Ref: TM-TNU1512
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS:4-Chloro-5-iodo-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - Halo-nucleoside, 7-Deaza-purine nucleoside.Fórmula:C11H11ClIN3O3Forma y color:SolidPeso molecular:395.58Ref: TM-TNU1025
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN4-Desmethyl-N5-Methyl wyosine
CAS:N4-Desmethyl-N5-Methyl wyosine is a Nucleoside Derivative - Bi-/Tri-cyclic nucleoside; naturally modified ribo-nucleoside.Fórmula:C14H17N5O5Forma y color:SolidPeso molecular:335.32Ref: TM-TNU0179
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-[6-(Diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hexofuranosyl]uracil
Nucleoside Derivatives - Phosphorus-containing nucleosides; 2’-Modified nucleosides; 5’-Modified nucleosidesForma y color:SoildRef: TM-TNU1286
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1,2'-O-Dimethyl guanosine
CAS:1,2'-O-Dimethyl guanosine is a Nucleoside Derivative - 3'-Modified nucleoside, N-Methylated/ alkylated nucleoside.Fórmula:C12H17N5O5Forma y color:SolidPeso molecular:311.29Ref: TM-TNU0572
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarIsocytidine
CAS:Nucleosides - isocytidine derivativeFórmula:C9H13N3O5Forma y color:SolidPeso molecular:243.22Ref: TM-TNU0049
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2',3',5'-Tri-O-benzoyl-5-methoxyuridine
CAS:2',3',5'-Tri-O-benzoyl-5-methoxyuridine is a 5-Modified Pyrimidine Nucleoside.Fórmula:C31H26N2O10Forma y color:SolidPeso molecular:586.55Ref: TM-TNU0806
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2-Methoxy-9-(β-D-ribofuranosyl)purine
CAS:Nucleoside Derivatives - 6-De-aminopurine nucleosides, 2-Modified purine nucleosidesFórmula:C11H14N4O5Forma y color:SolidPeso molecular:282.25Ref: TM-TNU1109
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-2'-fluoro-N1-methyl inosine
CAS:Nucleoside Derivatives - 2’-Modified nucleosides, Fluoro-modified nucleosides, N-Methylated /alkylated nucleosidesFórmula:C11H13FN4O4Forma y color:SolidPeso molecular:284.24Ref: TM-TNU0548
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Chloro-2'-deoxyuridine
CAS:2'-Chloro-2'-deoxyuridine is a Halo-nucleoside.Fórmula:C9H11ClN2O5Forma y color:SolidPeso molecular:262.65Ref: TM-TNU0073
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-N6,N6-dimethyladenosine
CAS:2'-Deoxy-N6,N6-dimethyladenosine is a Nucleoside Derivative - 6-Modified purine nucleoside.Fórmula:C12H17N5O3Forma y color:SolidPeso molecular:279.3Ref: TM-TNU1369
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-(b-D-Xylofuranosyl)-5-methylcytosine
CAS:Nucleoside Derivatives –5-Modified pyrimidine nucleosides；Xylo-nucleosidesFórmula:C10H15N3O5Forma y color:SolidPeso molecular:257.24Ref: TM-TNU0521
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3'-O-Methyl-5-methyluridine
CAS:3'-O-Methyl-5-methyluridine is a Nucleoside Derivative - 3'-Modified nucleoside.Fórmula:C11H16N2O6Forma y color:SolidPeso molecular:272.25Ref: TM-TNU1393
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine
CAS:Nucleoside Derivatives - Xylo-nucleosides; 8-Modified purine nucleosides; Amino nucleosides; N-Methylated alkylated nucleosidesFórmula:C14H20N6O6Forma y color:SolidPeso molecular:368.35Ref: TM-TNU0387
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine
CAS:6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine is a 2'-C-Methyl nucleoside; Halo-nucleoside.Fórmula:C32H25ClN4O7Forma y color:SolidPeso molecular:613.02Ref: TM-TNU0772
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-(b-D-Xylofuranosyl)-5-trifluoromethyluracil
1-(b-D-Xylofuranosyl)-5-trifluoromethyluracil is a Nucleoside Derivative - Xylo-nucleoside, Fluoro-modified nucleoside, 5-Modified pyrimidine nucleoside.Forma y color:SoildRef: TM-TNU1483
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2-Cyanoadenosine
CAS:Nucleoside Derivatives - 2’-Modified purine nucleosidesFórmula:C11H12N6O4Forma y color:SolidPeso molecular:292.25Ref: TM-TNU0296
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar5-Iodoarabinouridine
CAS:5-Iodoarabinouridine is a Halo-nucleoside; Arabino-nucleoside.Fórmula:C9H11IN2O6Forma y color:SolidPeso molecular:370.1Ref: TM-TNU0784
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN1-Ethylpseudouridine
CAS:N1-Ethylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Methylated nucleoside.Fórmula:C11H16N2O6Forma y color:SolidPeso molecular:272.25Ref: TM-TNU0062
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine
CAS:2'-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a Nucleoside Derivative - 6-Modified purine nucleoside.Fórmula:C18H20N6O6Forma y color:SolidPeso molecular:416.39Ref: TM-TNU1005
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarKS15
CAS:KS15 is a cryptochrome (CRY) inhibitor that promotes G1 cell cycle arrest, enhances drug sensitivity in MCF-7 cells, antitumour against human breast cancer.Fórmula:C20H22BrNO4Forma y color:SolidPeso molecular:420.33'-O-DMTr-thymidine 5'-CE phosphoramidite
CAS:3'-O-DMTr-thymidine 5'-CE phosphoramidite (2'-OMe-U Phosphoramidite) is a purine nucleoside analog and phosphoramidite derivative .Fórmula:C40H49N4O8PPureza:99.42%Forma y color:SolidPeso molecular:744.81Lifitegrast sodium
CAS:Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Fórmula:C29H23Cl2N2NaO7SPureza:99.33%Forma y color:SolidPeso molecular:637.46GP-82996
CAS:GP-82996 (CINK4) inhibits CDK4/6; IC50s: 1.5 μM (CDK4/D1), 5.6 μM (CDK6/D1), 25 μM (Cdk5/p35); triggers U2OS cancer cell apoptosis.Fórmula:C27H32N6OPureza:99.94%Forma y color:SolidPeso molecular:456.58HDGFRP2/PSIP1-IN-1
CAS:Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual inhibitor targeting the PWWP domains of Hepatoma-derived Growth Factor Related Protein 2 (HDGFRP2) and its homologue PSIP1. This compound effectively hinders the occurrence and progression of Diffuse Intrinsic Pontine Glioma (DIPG). It demonstrates binding affinity with a Kd value of 7 μM for HDGFRP2, indicative of its efficient ligand efficacy at 0.47. Additionally, Compound BPP exhibits a Kd value of 27 μM when binding to the PSIP1 PWWP domain, and a Kd value of 14 μM against HDGFRP3, confirming its potency as an inhibitor within the HDGFRP2 PWWP subfamily.Fórmula:C8H6BrN3Forma y color:SolidPeso molecular:224.06Napropamide
CAS:Napropamide is an acetamide herbicide that inhibits root growth to control annual grasses and broadleaf weeds.Fórmula:C17H21NO2Pureza:99.14%Forma y color:Colorless Crystals; (Tech Brown Solid) White-Like CrystalPeso molecular:271.35N-6-Furfurylguanosine
CAS:N-6-Furfurylguanosine (kinetin riboside) is a purine nucleoside analog with cytotoxicity, inhibiting the growth of cancer cells.Fórmula:C15H18N6O5Pureza:99.58%Forma y color:SolidPeso molecular:362.345,6-Dihydrothymidine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Fórmula:C10H16N2O5Pureza:99.90%Forma y color:SolidPeso molecular:244.24(S)-GNA-T-phosphoramidite
CAS:(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.Fórmula:C38H47N4O7PPureza:97.08%Forma y color:SolidPeso molecular:702.782'-O-Methyl-5-methyl uridine
CAS:2'-O-Methyl-5-methyl uridine is a 2'-O-Methyl nucleoside.Fórmula:C11H16N2O6Forma y color:SolidPeso molecular:272.25Ref: TM-TNU0716
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar5-Aza-7-deazaguanine
CAS:5-Aza-7-deazaguanine is a non-natural substituted nucleobase with potential antiviral activity, used in cancer and bacterial infection research.Fórmula:C5H5N5OPureza:98.87%Forma y color:SolidPeso molecular:151.13Yuanhuacine
CAS:Gnidilatidin is a biochemical.Fórmula:C37H44O10Forma y color:SolidPeso molecular:648.7492'-O-Methyl isocytidine
CAS:Isocytidine derivative; 2’-O-Methyl nucleosideFórmula:C10H15N3O5Forma y color:SolidPeso molecular:257.24Ref: TM-TNU0050
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar6-Methylmercaptopurine riboside
CAS:6-Methylmercaptopurine riboside is a purine nucleoside analogue applicable to biochemical experiments and drug synthesis studies.Fórmula:C11H14N4O4SForma y color:SolidPeso molecular:298.32TCRS-417
CAS:TCRS-417 (T417) inhibits PBX1-DNA interaction in mammalian cells or cell clusters, used in autoimmune and neurodegenerative disease research.Fórmula:C25H19FN2O5Forma y color:SolidPeso molecular:446.43N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine
CAS:Nucleoside Derivatives - 2’-Modified nucleoside, Protected nucleosides with NH2/OH open; Ready for phosphorylationFórmula:C41H43N3O9Forma y color:SolidPeso molecular:721.79Ref: TM-TNU1115
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar(S)-GNA-G(iBu) phosphoramidite
CAS:(S)-GNA-G(iBu) phosphoramidite is a Nucleoside Derivative - Acyclic nucleoside;Nucleoside Phosphoramidite.Fórmula:C42H52N7O7PForma y color:SolidPeso molecular:797.88Ref: TM-TNU1440
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarX5050
CAS:X5050 is a REST inhibitor, with an EC 50 of 2.1 μM.Fórmula:C17H15N3O3Forma y color:SolidPeso molecular:309.325Cytidine (Standard)
CAS:Cytidine (Standard) is the standard substance of Cytidine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.Fórmula:C9H13N3O5Forma y color:Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:243.225-Bromocytidine
CAS:5-Bromocytidine is a nucleoside analog that is a key disinfection by-product of drinking water and may interfere with nucleic acid synthesis.Fórmula:C9H12BrN3O5Pureza:99.63%Forma y color:SolidPeso molecular:322.115'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine
CAS:5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine is a Nucleoside Derivative - 2'-Modified nucleoside; Protected nucleoside with NH2/OH open;Fórmula:C34H38N2O9Forma y color:SolidPeso molecular:618.67Ref: TM-TNU1094
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarCeftriaxone Sodium
CAS:Ceftriaxone Sodium is a sporotaxin antibiotic that inhibits GSK3β and Aurora B. It is used in the study of sepsis and infective endocarditis.Fórmula:C18H17N8NaO7S3Forma y color:SolidPeso molecular:576.5622'-Amino-2'-deoxy-b-D-arabino-5-methyl uridine
CAS:2'-Amino-2'-deoxy-b-D-arabino-5-methyl uridine is a purine nucleoside analog with potential antitumor activity.Fórmula:C10H15N3O5Pureza:96.76%Forma y color:SolidPeso molecular:257.24VP-U-6
CAS:VP-U-6 is a Nucleoside Phosphoramidite; Nucleoside Derivative - Phosphorus-containing nucleotide; 5'-Modified nucleoside.Fórmula:C24H40N4O9P2Forma y color:SolidPeso molecular:590.54Ref: TM-TNU1009
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarDOTA-cyclo(RGDfK)
CAS:DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.Fórmula:C43H67N13O14Forma y color:SoildPeso molecular:990.078-Hydroxyadenosine
CAS:8-Hydroxyadenosine (8-Oxoadenosine) is a purine nucleoside found in Torula yeast RNA.Fórmula:C10H13N5O5Pureza:99.71%Forma y color:SolidPeso molecular:283.24Verosudil
CAS:Verosudil (AR-12286), a ROCK1/2 inhibitor (Ki: 2 nM), lowers intraocular pressure in mice by enhancing aqueous outflow.Fórmula:C17H17N3O2SPureza:99.68%Forma y color:SolidPeso molecular:327.4Ref: TM-T60924
1mg55,00€5mg147,00€1mL*10mM (DMSO)161,00€10mg231,00€25mg370,00€50mg522,00€100mg692,00€A-674563
CAS:A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.Fórmula:C22H22N4OPureza:99.21%Forma y color:SolidPeso molecular:358.44GSK269962A hydrochloride
CAS:GSK269962A hydrochloride (GSK 269962 hydrochloride) is a ROCK inhibitor with anti-inflammatory and vasodilatory effects and inhibits ROCK1 and ROCK2.Fórmula:C29H31ClN8O5Forma y color:SolidPeso molecular:607.06TG-693
CAS:TG-693, Oral CLK1 inhibitor, promotes exon 31 skipping of dystrophin gene, inhibits CLK1 substrate phosphorylation, for Duchenne muscular dystrophy.Fórmula:C12H9N3Pureza:99.81%Forma y color:SolidPeso molecular:195.23GPRP
CAS:GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.Fórmula:C18H31N7O5Forma y color:White To Off-White PowderPeso molecular:425.48STD1T
CAS:STD1T is a USP2a inhibitor with anticancer activity that reduces levels of the cell cycle protein D1 protein in HCT116 colon cancer cells.Fórmula:C19H19N3O4S2Pureza:98.77%Forma y color:SolidPeso molecular:417.5PROTAC CDK9 Degrader-1
CAS:PROTAC CDK9 Degrader-1 is a selective PROTAC-based CDK9 degrader, composed of a Cereblon ligand and a CDK ligand.Fórmula:C33H35N5O7Pureza:95.1%Forma y color:SolidPeso molecular:613.66USP8-IN-1
CAS:USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 μM [1].Fórmula:C18H21N5O3SPureza:99.07%Forma y color:SoildPeso molecular:387.46Ref: TM-T60146
1mg84,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg250,00€25mg439,00€50mg620,00€100mg893,00€Belumosudil mesylate
CAS:Belumosudil mesylate (KD025 mesylate) is a ROCK2 inhibitor with antifibrotic activity, and can be used in chronic graft-versus-host disease research.Fórmula:C27H28N6O5SPureza:98.73%Forma y color:SolidPeso molecular:548.61Ref: TM-T39555
1mg34,00€2mg46,00€5mg71,00€1mL*10mM (DMSO)85,00€10mg96,00€25mg155,00€50mg230,00€100mg353,00€200mg517,00€Cotosudil
CAS:Cotosudil is a ROCK kinase inhibitor with antihypertensive activity used to treat or prevent neurodegenerative diseases.Fórmula:C16H21N3O2SPureza:98.41%Forma y color:SolidPeso molecular:319.42Maleic hydrazide
CAS:Maleic hydrazide is a plant germination inhibitor that participates in nucleic acid metabolism pathways ,inhibiting cell division in the apical meristem.Fórmula:C4H4N2O2Pureza:98.4%Forma y color:Crystals From Water Maleic Hydrazide Is An Odorless White Solid Sinks In Water (Uscg 1999)Peso molecular:112.09N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
CAS:N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity.Fórmula:C47H52N7O7PPureza:97.36%Forma y color:SolidPeso molecular:857.932'-O-Methylinosine
CAS:2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally bioavailable purine nucleoside analog with antihypertensive activity.Fórmula:C11H14N4O5Pureza:99.88%Forma y color:SolidPeso molecular:282.252',5-Difluoro-2'-deoxy-1-arabinosyluracil
CAS:2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepilepticFórmula:C9H10F2N2O5Pureza:99.99%Forma y color:SolidPeso molecular:264.18NU6102
CAS:NU6102 is a CDK2 inhibitor with antitumor activity against CDK1/cyclinB, CDK1/CDK2, CDK4, DYRK1A , PDK1, and ROCKII, and it can be used to study rectal cancer.Fórmula:C18H22N6O3SPureza:99.76%Forma y color:SolidPeso molecular:402.47LDC4297
CAS:LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.Fórmula:C23H28N8OPureza:98.25%Forma y color:SolidPeso molecular:432.52GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Fórmula:C20H11Cl2NO4Pureza:98%Forma y color:SolidPeso molecular:400.21IRES-C11
CAS:IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.Fórmula:C13H11Cl2NO4Pureza:99.89%Forma y color:SolidPeso molecular:316.14Ref: TM-T40419
1mg94,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.674,00€200mg2.242,00€Poloxime
CAS:Poloxime is a hydrolysis product of poloxin and is a non-ATP-competitive Plk1 inhibitor. It also has moderate Plk1 inhibitory activity.Fórmula:C10H13NO2Pureza:98%Forma y color:SolidPeso molecular:179.22TAME
CAS:Tosyl-L-Arginine Methyl Ester (TAME (N-4-Tosyl-L-arginine methyl ester)) is an APC inhibitor.Fórmula:C14H22N4O4SPureza:98%Forma y color:SolidPeso molecular:342.41Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Fórmula:C29H41F3N8O9Forma y color:SolidPeso molecular:702.68Nolatrexed dihydrochloride
CAS:Nolatrexed dihydrochloride (Thymitaq) is a soluble, lipophilic cancer drug that inhibits DNA replication, causing cell cycle arrest and apoptosis.Fórmula:C14H14Cl2N4OSPureza:97.02%Forma y color:Tan SolidPeso molecular:357.26CCT244747
CAS:CCT244747 is a potent and selective CHK1 inhibitor oral, ATP-competitive, and cytotoxic, abrogating drug-induced S and G2 blockade and inducing apoptosis .Fórmula:C20H24N8O2Pureza:99.17%Forma y color:SolidPeso molecular:408.46Ribociclib hydrochloride
CAS:Ribociclib hydrochloride (LEE011 HCl) is a selective, orally active cyclin-dependent kinase CDK4/6 inhibitor (IC50=10/39 nM) that inhibits proliferation.Fórmula:C23H31ClN8OPureza:99.87%Forma y color:SolidPeso molecular:471sAJM589
CAS:sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels and inhibiting the cellular proliferation.Fórmula:C16H10N2OPureza:98%Forma y color:SolidPeso molecular:246.26Synucleozid hydrochloride
CAS:Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.Fórmula:C22H21ClN6Pureza:98.13%Forma y color:SolidPeso molecular:404.9N,N-Dimethyl-2'-O-methylcytidine
CAS:N,N-Dimethyl-2'-O-methylcytidine (N4, N4, 2'-O-Trimethylcytidine) is a purine nucleoside analogue with anti-cancer activity.Fórmula:C12H19N3O5Pureza:99.62%Forma y color:SolidPeso molecular:285.38-Chloroinosine
CAS:8-Chloroinosine is a purine nucleoside analog and a metabolite of the anticancer compound 8-chloro-adenosine.Fórmula:C10H11ClN4O5Pureza:99.37% - 99.56%Forma y color:SolidPeso molecular:302.67Kinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Fórmula:C20H16Br2N4O4Pureza:97.24%Forma y color:SolidPeso molecular:536.17Ref: TM-T15663
2mg42,00€5mg63,00€1mL*10mM (DMSO)75,00€10mg90,00€25mg163,00€50mg237,00€100mg356,00€200mg526,00€5'-O-DMT-N2-ibu-dG
CAS:5'-O-DMT-N2-ibu-dG is a deoxynucleoside served as a building block in oligonucleotide synthesis, with protecting groups to prevent unwanted reactions.Fórmula:C35H37N5O7Pureza:98.71%Forma y color:SolidPeso molecular:639.78-Bromoadenosine
CAS:8-Bromoadenosine is an adenosine derivative. 8-Br-Adenosine inhibitis mitochondrial membrane potential, cytoplasmic Ca²⁺ levels, and RNA and protein synthesis.Fórmula:C10H12BrN5O4Pureza:99.11%Forma y color:SolidPeso molecular:346.14NSC 23766
CAS:NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.Fórmula:C24H35N7Pureza:99.49%Forma y color:SolidPeso molecular:421.58N2-Isobutyryl-2-deoxyguanosine
CAS:N2-Isobutyryl-2-deoxyguanosine（iBu-dG） is a nucleoside analog that can be used to synthesize oligonucleotides.Fórmula:C14H19N5O5Pureza:97.03%Forma y color:SolidPeso molecular:337.33APE1-IN-1
CAS:APE1-IN-1 is a purine/pyrimidine-free endonuclease 1 inhibitor with potential antitumor activity that enhances the toxicity of alkylating agents on cancer cellsFórmula:C19H21N3OS2Pureza:98.5%Forma y color:SolidPeso molecular:371.52PD 407824
CAS:PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).Fórmula:C20H12N2O3Pureza:98.02%Forma y color:SolidPeso molecular:328.322'-O-Methyl-5-iodouridine
CAS:2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a
Fórmula:C10H13IN2O6Pureza:99.89%Forma y color:SolidPeso molecular:384.12TG003
CAS:TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.Fórmula:C13H15NO2SPureza:99.46%Forma y color:SolidPeso molecular:249.33Ref: TM-T60367
1mg48,00€5mg92,00€10mg150,00€1mL*10mM (DMSO)167,00€25mg266,00€50mg440,00€100mg530,00€200mg767,00€3-Deazauridine
CAS:3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.Fórmula:C10H13NO6Pureza:99.86%Forma y color:SolidPeso molecular:243.21kb-NB77-78
CAS:kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).Fórmula:C18H25NO3SiPureza:99.54%Forma y color:SolidPeso molecular:331.48Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Forma y color:SolidPeso molecular:355.36Palbociclib Isethionate
CAS:Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。Fórmula:C24H29N7O2·C2H6O4SPureza:99.01% - 99.27%Forma y color:SolidPeso molecular:573.66EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Fórmula:C25H29Cl2F3N2O4SPureza:98.39% - 99.42%Forma y color:SolidPeso molecular:581.47Bractoppin
CAS:Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibitsFórmula:C25H23FN4OPureza:98.38%Forma y color:SolidPeso molecular:414.47Ref: TM-T8873
1mg50,00€5mg99,00€1mL*10mM (DMSO)109,00€10mg158,00€25mg309,00€50mg465,00€100mg697,00€500mg1.404,00€Metoprine
CAS:Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.Fórmula:C11H10Cl2N4Pureza:98.42%Forma y color:SolidPeso molecular:269.13AT13148
CAS:AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.Fórmula:C17H16ClN3OPureza:98.04% - ≥95%Forma y color:SolidPeso molecular:313.78TH-263
CAS:TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.Fórmula:C21H20N2O3SPureza:99.54%Forma y color:SolidPeso molecular:380.46Ref: TM-T19578
2mg34,00€5mg49,00€1mL*10mM (DMSO)54,00€10mg75,00€25mg137,00€50mg192,00€100mg281,00€200mg419,00€Activated Protein C (390-404), human acetate
Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.Fórmula:C93H134N22O25Pureza:99.92%Forma y color:SolidPeso molecular:1960.19PFM01
CAS:PFM01 inhibits MRE11 enzyme, steering DSBR towards NHEJ over HR.Fórmula:C14H15NO2S2Pureza:98.68%Forma y color:SolidPeso molecular:293.4ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Fórmula:C17H21ClN2O4SPureza:99.33% - 99.45%Forma y color:SolidPeso molecular:384.88R-IMPP
CAS:R-IMPP is an inhibitor of PCSK9 translation.Fórmula:C24H27N3O2Pureza:99.47% - 99.85%Forma y color:SolidPeso molecular:389.49Ref: TM-T4058
1mg46,00€2mg56,00€1mL*10mM (DMSO)75,00€5mg88,00€10mg140,00€25mg280,00€50mg500,00€100mg718,00€GNE-6640
CAS:GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).Fórmula:C20H18N4OPureza:98.64%Forma y color:SolidPeso molecular:330.38Ref: TM-T5461
1mg66,00€2mg96,00€5mg144,00€1mL*10mM (DMSO)158,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€6-Chloropurine riboside
CAS:6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.Fórmula:C10H11ClN4O4Pureza:96.84%Forma y color:SoildPeso molecular:286.6700
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