Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
Mostrar 10 subcategorías más
Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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MSC2530818
CAS:<p>MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).</p>Fórmula:C18H17ClN4OPureza:98.93%Forma y color:SolidPeso molecular:340.81GDC-0575
CAS:<p>GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).</p>Fórmula:C16H20BrN5OPureza:≥95%Forma y color:SolidPeso molecular:378.27TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Forma y color:SolidPeso molecular:588.07HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Fórmula:C13H15N3O2SPureza:99.44%Forma y color:Pale Yellow Crystalline SolidPeso molecular:277.34Zoliflodacin
CAS:<p>Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.</p>Fórmula:C22H22FN5O7Pureza:99.82% - 99.93%Forma y color:SolidPeso molecular:487.44BS-181 dihydrochloride
CAS:<p>BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.</p>Fórmula:C22H34Cl2N6Forma y color:SolidPeso molecular:453.46GNF2133 hydrochloride
CAS:<p>GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.</p>Fórmula:C24H31ClN6O2Forma y color:SolidPeso molecular:471.06-Thio-2'-Deoxyguanosine
CAS:<p>6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.</p>Fórmula:C10H13N5O3SPureza:97.52%Forma y color:SolidPeso molecular:283.31POL1-IN-1
CAS:<p>POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。</p>Fórmula:C21H20N6Pureza:98% - 98.01%Forma y color:SolidPeso molecular:356.42Ocifisertib(CFI-400945 free base)
CAS:<p>Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4.Cost-effective and quality-assured.</p>Fórmula:C33H34N4O3Pureza:98.53% - 99.04%Forma y color:SolidPeso molecular:534.65N1-Methylpseudouridine
CAS:<p>N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by</p>Fórmula:C10H14N2O6Pureza:98.95% - 99.88%Forma y color:SolidPeso molecular:258.23LJI308
CAS:<p>LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.</p>Fórmula:C21H18F2N2O2Pureza:99.73% - 99.87%Forma y color:SolidPeso molecular:368.38Acelarin
CAS:<p>Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.</p>Fórmula:C25H27F2N4O8PPureza:99.26%Forma y color:SolidPeso molecular:580.47CYC-116
CAS:<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Fórmula:C18H20N6OSPureza:97.36% - 97.59%Forma y color:SolidPeso molecular:368.46THZ1
CAS:<p>THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.</p>Fórmula:C31H28ClN7O2Pureza:95.09% - 99.27%Forma y color:SolidPeso molecular:566.05PFM01
CAS:<p>PFM01 inhibits MRE11 enzyme, steering DSBR towards NHEJ over HR.</p>Fórmula:C14H15NO2S2Pureza:98.68%Forma y color:SolidPeso molecular:293.4Simeprevir
CAS:<p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>Fórmula:C38H47N5O7S2Pureza:99.45% - 99.92%Forma y color:SolidPeso molecular:749.94Aurora kinase inhibitor-3
CAS:<p>Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,</p>Fórmula:C21H18F3N5OPureza:98.91%Forma y color:SolidPeso molecular:413.4GW406108X(Z/E)
CAS:<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Fórmula:C20H11Cl2NO4Pureza:98.23%Forma y color:SolidPeso molecular:400.21Dalpiciclib
CAS:<p>Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.</p>Fórmula:C25H30N6O2Pureza:99.69%Forma y color:SolidPeso molecular:446.54MLN8054
CAS:<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Fórmula:C25H15ClF2N4O2Pureza:98.07% - 98.26%Forma y color:SolidPeso molecular:476.86A-205804
CAS:<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Fórmula:C15H12N2OS2Pureza:98.07% - 98.52%Forma y color:SolidPeso molecular:300.4TH588 hydrochloride
CAS:<p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>Fórmula:C13H13Cl3N4Forma y color:SolidPeso molecular:331.63Methotrexate metabolite
CAS:<p>DAMPA, active metabolite of Methotrexate, is a chemotherapeutic and immunosuppressive folic acid antagonist.</p>Fórmula:C15H15N7O2Pureza:95.60% - 97.59%Forma y color:SolidPeso molecular:325.33SBC-115337
CAS:<p>SBC-115337 is a PCSK9 inhibitor.</p>Fórmula:C29H19N3O4Pureza:99.41%Forma y color:SolidPeso molecular:473.48BTYNB
CAS:<p>BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.</p>Fórmula:C12H9BrN2OSPureza:≥95%Forma y color:SolidPeso molecular:309.18Y16 acetate(429653-73-6 free base)
<p>Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA</p>Fórmula:C51H74N14O13Pureza:98%Forma y color:SolidPeso molecular:1091.24Briciclib
CAS:<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Fórmula:C19H23O10PSPureza:98% - 99.84%Forma y color:SolidPeso molecular:474.42Nemorubicin
CAS:<p>Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.</p>Fórmula:C32H37NO13Pureza:97.4%Forma y color:SolidPeso molecular:643.64Amenamevir
CAS:<p>Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL</p>Fórmula:C24H26N4O5SPureza:99.00% - 99.86%Forma y color:SolidPeso molecular:482.55Garenoxacin mesylate hydrate
CAS:<p>Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains</p>Fórmula:C23H20F2N2O4·CH4O3S·H2OPureza:99.56%Forma y color:SolidPeso molecular:540.53CCT245737
CAS:<p>CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.</p>Fórmula:C16H16F3N7OPureza:98.06% - 99.69%Forma y color:SolidPeso molecular:379.34IMP-1088
CAS:<p>IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.</p>Fórmula:C25H29F2N5OPureza:98.48% - 99.52%Forma y color:SolidPeso molecular:453.53TAK-960 monohydrochloride
CAS:<p>TAK-960 monohydrochloride, an oral compound, inhibits PLK1 (IC50=0.8 nM), PLK2, PLK3, stunts cancer cell growth, and is effective in tumor models.</p>Fórmula:C27H35ClF3N7O3Forma y color:SolidPeso molecular:598.07Pritelivir
CAS:<p>Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).</p>Fórmula:C18H18N4O3S2Pureza:97.96% - 99.42%Forma y color:SolidPeso molecular:402.49Senexin A
CAS:<p>Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.</p>Fórmula:C17H14N4Pureza:99.74%Forma y color:SolidPeso molecular:274.32SEL120-34A HCl
CAS:<p>SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectively</p>Fórmula:C15H19Br2ClN4Pureza:98.13% - 98.47%Forma y color:SolidPeso molecular:450.6FEN1-IN-SC13
CAS:<p>FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)</p>Fórmula:C24H23N3O3SPureza:98.02%Forma y color:SolidPeso molecular:433.52Palbociclib
CAS:<p>Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.</p>Fórmula:C24H29N7O2Pureza:98% - 99.9%Forma y color:SolidPeso molecular:447.53LY2334737
CAS:<p>LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.</p>Fórmula:C17H25F2N3O5Pureza:98.82%Forma y color:SolidPeso molecular:389.39MLS-573151
CAS:<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Fórmula:C21H19N3O2SPureza:98.80%Forma y color:SolidPeso molecular:377.46Dalpiciclib hydrochloride
<p>Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.</p>Fórmula:C25H31ClN6O2Forma y color:SolidPeso molecular:483.01SBC-110736
CAS:<p>SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor</p>Fórmula:C26H27N3O2Pureza:99.44%Forma y color:SolidPeso molecular:413.51DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:<p>DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.</p>Fórmula:C41H49N4O9PPureza:98.28%Forma y color:SolidPeso molecular:772.82FOY 251
CAS:<p>FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.</p>Fórmula:C17H19N3O7SPureza:97.11% - 99.33%Forma y color:SolidPeso molecular:409.415-BrdU
CAS:<p>5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!</p>Fórmula:C9H11BrN2O5Pureza:99.54% - 99.87%Forma y color:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:307.1TAK-960 hydrochloride
CAS:<p>TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.</p>Fórmula:C27H35ClF3N7O3Forma y color:SolidPeso molecular:598.06BMS-1166
CAS:<p>BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.</p>Fórmula:C36H33ClN2O7Pureza:99.22%Forma y color:SolidPeso molecular:641.11SCH900776
CAS:<p>SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.</p>Fórmula:C15H18BrN7Pureza:96.69% - 99.6%Forma y color:SolidPeso molecular:376.25TH5427 hydrochloride
CAS:<p>TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.</p>Fórmula:C20H21Cl3N8O3Forma y color:SolidPeso molecular:527.79Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Fórmula:C32H46O8Pureza:97.1% - 99.33%Forma y color:SolidPeso molecular:558.7Ibezapolstat
CAS:<p>Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.</p>Fórmula:C18H20Cl2N6O2Pureza:98% - 99.429%Forma y color:SolidPeso molecular:423.3RI-1
CAS:<p>RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).</p>Fórmula:C14H11Cl3N2O3Pureza:99.3% - 99.62%Forma y color:SolidPeso molecular:361.61Y16
CAS:<p>Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.</p>Fórmula:C24H20N2O3Pureza:98.26% - 99.32%Forma y color:SolidPeso molecular:384.43TMPyP4 tosylate
CAS:<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Fórmula:C72H66N8O12S4Pureza:98.61% - 99.85%Forma y color:SolidPeso molecular:1363.6RNase L-IN-2
CAS:<p>RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.</p>Fórmula:C16H14N2O2SPureza:98.81%Forma y color:SolidPeso molecular:298.365'-Deoxy-5-fluorocytidine
CAS:<p>5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.</p>Fórmula:C9H12FN3O4Pureza:99.67%Forma y color:White SolidPeso molecular:245.21PNU112455A hydrochloride
CAS:<p>PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.</p>Fórmula:C10H12ClN5O2SPureza:98.58% - 99.22%Forma y color:SolidPeso molecular:301.75Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Fórmula:C22H39ClN2O6SPureza:98.81% - >99.99%Forma y color:White SolidPeso molecular:495.07STAMBP-IN-1
CAS:<p>STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after</p>Fórmula:C27H28N4O4SPureza:99.64%Forma y color:SolidPeso molecular:504.62-Aminofluorene
CAS:<p>2-Aminofluorene (2-Fluorenamine) is a biochemical.</p>Fórmula:C13H11NPureza:99.9%Forma y color:Light Yellow CrystallinePeso molecular:181.23ON-013100
CAS:<p>ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.</p>Fórmula:C19H22O7SPureza:98.27%Forma y color:SolidPeso molecular:394.44Pyridostatin
CAS:<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Fórmula:C31H32N8O5Pureza:98%Forma y color:SolidPeso molecular:596.64Ribociclib succinate hydrate
CAS:<p>Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).</p>Fórmula:C27H38N8O6Pureza:98%Forma y color:SolidPeso molecular:570.65110074-G5
CAS:<p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>Fórmula:C18H12N4O3Pureza:99.51% - 99.67%Forma y color:SolidPeso molecular:332.31IMM-H007
CAS:<p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>Fórmula:C22H23N5O8Pureza:97.73%Forma y color:SolidPeso molecular:485.45Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Fórmula:C18H15N5OPureza:97.03%Forma y color:SolidPeso molecular:317.34A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Fórmula:C24H27N3O4SPureza:97.81%Forma y color:SolidPeso molecular:453.55Adavosertib
CAS:<p>Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.</p>Fórmula:C27H32N8O2Pureza:98.65% - 99.86%Forma y color:SolidPeso molecular:500.6PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Forma y color:SolidPeso molecular:419.48ML216
CAS:<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Fórmula:C15H9F4N5OSPureza:98.12%Forma y color:SolidPeso molecular:383.32Fadraciclib
CAS:<p>Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).</p>Fórmula:C21H31N7OPureza:99.75%Forma y color:SolidPeso molecular:397.52Mitonafide
CAS:<p>Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.</p>Fórmula:C16H15N3O4Pureza:99.89%Forma y color:SolidPeso molecular:313.31CHR-6494 TFA
CAS:<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Fórmula:C18H17F3N6O2Pureza:99.50%Forma y color:SolidPeso molecular:406.36CAN508
CAS:<p>CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.</p>Fórmula:C9H10N6OPureza:98.65%Forma y color:SolidPeso molecular:218.22CK7
CAS:<p>CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.</p>Fórmula:C14H12N6O2SPureza:99.54%Forma y color:SolidPeso molecular:328.35HMN-214
CAS:<p>HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.</p>Fórmula:C22H20N2O5SPureza:98% - >99.99%Forma y color:SolidPeso molecular:424.47TAK-960
CAS:<p>TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.</p>Fórmula:C27H34F3N7O3Pureza:97.06%Forma y color:SolidPeso molecular:561.6Indisulam
CAS:<p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>Fórmula:C14H12ClN3O4S2Pureza:98.68% - 99.77%Forma y color:SolidPeso molecular:385.85Cyclo(-RGDfK) TFA
CAS:<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Fórmula:C29H42F3N9O9Pureza:98.99% - 99.54%Forma y color:SolidPeso molecular:717.69GSK2850163 hydrochloride
CAS:<p>GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.</p>Fórmula:C24H30Cl3N3OForma y color:SolidPeso molecular:482.87TAK-632
CAS:<p>TAK-632 is a potent pan-Raf inhibitor.</p>Fórmula:C27H18F4N4O3SPureza:98% - 99.5%Forma y color:SolidPeso molecular:554.52SBC-115076
CAS:<p>SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.</p>Fórmula:C31H33N3O5Pureza:97.07% - 99.89%Forma y color:SolidPeso molecular:527.617BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Fórmula:C16H10BrN3O2Pureza:99.67%Forma y color:SolidPeso molecular:356.17Apcin-A
CAS:<p>Apcin-A is an anaphase-promoting complex (APC) inhibitor.</p>Fórmula:C10H14Cl3N5O2Forma y color:SolidPeso molecular:342.61Roniciclib
CAS:<p>Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.</p>Fórmula:C18H21F3N4O3SPureza:98% - 98.63%Forma y color:SolidPeso molecular:430.44GLPG0187
CAS:<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Fórmula:C29H37N7O5SPureza:99.4% - 99.70%Forma y color:SolidPeso molecular:595.71Tiazofurin
CAS:<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Fórmula:C9H12N2O5SPureza:99.91%Forma y color:SolidPeso molecular:260.272'-Deoxy-2'-fluorocytidine
CAS:<p>2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.</p>Fórmula:C9H12FN3O4Pureza:99.90%Forma y color:White Or Almost White Crystalline PowderPeso molecular:245.21Cetraxate hydrochloride
CAS:<p>Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.</p>Fórmula:C17H24ClNO4Pureza:99.75%Forma y color:SolidPeso molecular:341.83PF-06873600
CAS:<p>PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.</p>Fórmula:C20H27F2N5O4SPureza:98.77% - 99.55%Forma y color:SolidPeso molecular:471.52Hu7691
CAS:<p>Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.</p>Fórmula:C22H22ClF3N4OPureza:99.81%Forma y color:SolidPeso molecular:450.88Risdiplam
CAS:<p>Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.</p>Fórmula:C22H23N7OPureza:98.68% - 99.64%Forma y color:SolidPeso molecular:401.46Palmatine
CAS:<p>Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.</p>Fórmula:C21H22NO4Pureza:96.28% - 99.49%Forma y color:SolidPeso molecular:352.4AT7519 TFA
CAS:<p>AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.</p>Fórmula:C18H18Cl2F3N5O4Forma y color:SolidPeso molecular:496.27Poloxin
CAS:<p>Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).</p>Fórmula:C18H19NO3Pureza:99.19%Forma y color:SolidPeso molecular:297.35Palbociclib dihydrochloride
<p>Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.</p>Fórmula:C24H31Cl2N7O2Forma y color:SolidPeso molecular:520.45SPHINX
CAS:<p>SPHINX is a new generation inhibitor of SPRK1</p>Fórmula:C17H17F3N2O3Pureza:99.29%Forma y color:SolidPeso molecular:354.32Cdk5 Substrate acetate
<p>Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.</p>Fórmula:C55H103N15O14Pureza:96.21%Forma y color:SolidPeso molecular:1198.5AZD-5438
CAS:<p>AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).</p>Fórmula:C18H21N5O2SPureza:99.73% - 99.87%Forma y color:SolidPeso molecular:371.46
