Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(115 productos)
- CDK(547 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(269 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(273 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
Mostrar 10 subcategorías más
Se han encontrado 3909 productos de "Ciclo celular / Checkpoint"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Forma y color:SolidPeso molecular:355.36GPRP acetate (67869-62-9 free base)
CAS:GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.
Fórmula:C20H35N7O7Pureza:>99.99%Forma y color:SolidPeso molecular:485.53BS-181 dihydrochloride
CAS:BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.Fórmula:C22H34Cl2N6Forma y color:SolidPeso molecular:453.46Cetraxate hydrochloride
CAS:Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.Fórmula:C17H24ClNO4Pureza:99.75%Forma y color:SolidPeso molecular:341.83WNK463
CAS:WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).Fórmula:C21H24F3N7O2Pureza:>99.99% - ≥95%Forma y color:SolidPeso molecular:463.46TH588
CAS:TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Fórmula:C13H12Cl2N4Pureza:96.05% - 99.82%Forma y color:SolidPeso molecular:295.171,4-Anthraquinone
CAS:1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.Fórmula:C14H8O2Pureza:95.96% - 97.01%Forma y color:Orange Brown SolidPeso molecular:208.21CDK9-IN-30
CAS:CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.Fórmula:C16H20FNO3Pureza:99.75%Forma y color:SolidPeso molecular:293.33Temozolomide Acid
CAS:TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.Fórmula:C6H5N5O3Pureza:99.28%Forma y color:SolidPeso molecular:195.14PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Fórmula:C18H21Cl3N4OPureza:99.5%Forma y color:SolidPeso molecular:415.75DMT-2′Fluoro-dU Phosphoramidite
CAS:DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.Fórmula:C39H46FN4O8PPureza:99.5%Forma y color:SolidPeso molecular:748.78MLN0905
CAS:MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).Fórmula:C24H25F3N6SPureza:98% - 99.92%Forma y color:SolidPeso molecular:486.56Zoliflodacin
CAS:Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.Fórmula:C22H22FN5O7Pureza:99.82% - 99.93%Forma y color:SolidPeso molecular:487.44Ref: TM-TQ0063
1mg105,00€5mg245,00€1mL*10mM (DMSO)264,00€10mg389,00€25mg645,00€50mg888,00€100mg1.234,00€500mg2.457,00€TH588 hydrochloride
CAS:TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.Fórmula:C13H13Cl3N4Forma y color:SolidPeso molecular:331.63Ibezapolstat
CAS:Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.Fórmula:C18H20Cl2N6O2Pureza:98% - 99.429%Forma y color:SolidPeso molecular:423.3Ref: TM-T10243
1mg50,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg170,00€25mg340,00€50mg557,00€100mg893,00€5'-Deoxy-5-fluorocytidine
CAS:5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.Fórmula:C9H12FN3O4Pureza:99.67%Forma y color:White SolidPeso molecular:245.21IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFórmula:C22H23N5O8Pureza:97.73%Forma y color:SolidPeso molecular:485.45Ref: TM-T9010
1mg40,00€5mg96,00€1mL*10mM (DMSO)131,00€10mg135,00€25mg226,00€50mg320,00€100mg434,00€200mg602,00€Mitonafide
CAS:Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.Fórmula:C16H15N3O4Pureza:99.89%Forma y color:SolidPeso molecular:313.31Ref: TM-T25817
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg90,00€25mg178,00€50mg295,00€100mg484,00€200mg690,00€500mg1.035,00€CHR-6494 TFA
CAS:CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Fórmula:C18H17F3N6O2Pureza:99.50%Forma y color:SolidPeso molecular:406.36Ref: TM-T9521
1mg60,00€5mg122,00€1mL*10mM (DMSO)142,00€10mg190,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€Apcin-A
CAS:Apcin-A is an anaphase-promoting complex (APC) inhibitor.Fórmula:C10H14Cl3N5O2Forma y color:SolidPeso molecular:342.61Palbociclib dihydrochloride
Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.Fórmula:C24H31Cl2N7O2Forma y color:SolidPeso molecular:520.45Sarecycline free base
CAS:Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.Fórmula:C24H29N3O8Pureza:98%Forma y color:SolidPeso molecular:487.5AT7519 TFA
CAS:AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.Fórmula:C18H18Cl2F3N5O4Forma y color:SolidPeso molecular:496.27Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Fórmula:C9H12N2O5SPureza:99.91%Forma y color:SolidPeso molecular:260.27SBC-115076
CAS:SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.Fórmula:C31H33N3O5Pureza:97.07% - 99.89%Forma y color:SolidPeso molecular:527.61Ref: TM-T2626
1mg38,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg94,00€25mg172,00€50mg309,00€100mg477,00€500mg1.063,00€GSK2850163 hydrochloride
CAS:GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.Fórmula:C24H30Cl3N3OForma y color:SolidPeso molecular:482.87Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Fórmula:C18H15N5OPureza:97.03%Forma y color:SolidPeso molecular:317.342-Aminofluorene
CAS:2-Aminofluorene (2-Fluorenamine) is a biochemical.Fórmula:C13H11NPureza:99.9%Forma y color:Light Yellow CrystallinePeso molecular:181.23STAMBP-IN-1
CAS:STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release afterFórmula:C27H28N4O4SPureza:99.64%Forma y color:SolidPeso molecular:504.6Ref: TM-T8706
1mg67,00€5mg152,00€1mL*10mM (DMSO)192,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€RNase L-IN-2
CAS:RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.Fórmula:C16H14N2O2SPureza:98.81%Forma y color:SolidPeso molecular:298.36Ref: TM-T8591
1mg120,00€1mL*10mM (DMSO)243,00€5mg264,00€10mg395,00€25mg627,00€50mg890,00€100mg1.198,00€200mg1.603,00€TH5427 hydrochloride
CAS:TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.Fórmula:C20H21Cl3N8O3Forma y color:SolidPeso molecular:527.79TAK-960 hydrochloride
CAS:TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.Fórmula:C27H35ClF3N7O3Forma y color:SolidPeso molecular:598.06FOY 251
CAS:FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.Fórmula:C17H19N3O7SPureza:97.11% - 99.33%Forma y color:SolidPeso molecular:409.41Ref: TM-T8676
1mg51,00€5mg110,00€1mL*10mM (DMSO)126,00€10mg177,00€25mg300,00€50mg424,00€100mg605,00€500mg1.198,00€SBC-110736
CAS:SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitorFórmula:C26H27N3O2Pureza:99.44%Forma y color:SolidPeso molecular:413.51FEN1-IN-SC13
CAS:FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)
Fórmula:C24H23N3O3SPureza:98.02%Forma y color:SolidPeso molecular:433.52TAK-960 monohydrochloride
CAS:TAK-960 monohydrochloride, an oral compound, inhibits PLK1 (IC50=0.8 nM), PLK2, PLK3, stunts cancer cell growth, and is effective in tumor models.Fórmula:C27H35ClF3N7O3Forma y color:SolidPeso molecular:598.07Garenoxacin mesylate hydrate
CAS:Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strainsFórmula:C23H20F2N2O4·CH4O3S·H2OPureza:99.56%Forma y color:SolidPeso molecular:540.53Nemorubicin
CAS:Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.
Fórmula:C32H37NO13Pureza:97.4%Forma y color:SolidPeso molecular:643.64Methotrexate metabolite
CAS:DAMPA, active metabolite of Methotrexate, is a chemotherapeutic and immunosuppressive folic acid antagonist.Fórmula:C15H15N7O2Pureza:95.60% - 97.59%Forma y color:SolidPeso molecular:325.33PFM01
CAS:PFM01 inhibits MRE11 enzyme, steering DSBR towards NHEJ over HR.Fórmula:C14H15NO2S2Pureza:98.68%Forma y color:SolidPeso molecular:293.4LJI308
CAS:LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.Fórmula:C21H18F2N2O2Pureza:99.73% - 99.87%Forma y color:SolidPeso molecular:368.38N1-Methylpseudouridine
CAS:N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms byFórmula:C10H14N2O6Pureza:98.95% - 99.88%Forma y color:SolidPeso molecular:258.23TCS7010
CAS:TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Forma y color:SolidPeso molecular:588.07MSC2530818
CAS:MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).Fórmula:C18H17ClN4OPureza:98.93%Forma y color:SolidPeso molecular:340.81Ref: TM-TQ0266
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg462,00€50mg692,00€100mg964,00€Talotrexin
CAS:Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.Fórmula:C27H27N9O6Forma y color:SolidPeso molecular:573.56LY3405105
CAS:LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-Fórmula:C26H39N7O3Pureza:99.66%Forma y color:SolidPeso molecular:497.63Mps1-IN-1 dihydrochloride
CAS:Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.Fórmula:C28H35Cl2N5O4SForma y color:SolidPeso molecular:608.58Pyridostatin hydrochloride
CAS:Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.Fórmula:C31H37Cl5N8O5Forma y color:SolidPeso molecular:778.94S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Fórmula:C22H21NO2SPureza:97.02%Forma y color:Almost White To Light Yellow Granular PowderPeso molecular:363.47Dasabuvir sodium
CAS:Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).Fórmula:C26H26N3NaO5SForma y color:SolidPeso molecular:515.56Verosudil hydrochloride
CAS:Verosudil (AR-12286) is a selective Rho kinase inhibitor, reducing IOP in XFS & OHT/XFG, offering a new treatment option.Fórmula:C17H18ClN3O2SForma y color:SolidPeso molecular:363.86TAK-960 dihydrochloride
TAK-960 dihydrochloride: oral PLK1 inhibitor, IC50 0.8 nM; also Hinders PLK2 and PLK3 (IC50s 16.9/50.2 nM); curbs cancer cell growth.Fórmula:C27H36Cl2F3N7O3Forma y color:SolidPeso molecular:634.52Ganciclovir hydrate
CAS:Ganciclovir hydrate: oral anti-cytomegalovirus; inhibits HSV 1/2, CMV, adenoviruses, FHV-1; brain-penetrating.Fórmula:C9H15N5O5Forma y color:SolidPeso molecular:273.249Netarsudil free base
CAS:Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Fórmula:C28H27N3O3Forma y color:SolidPeso molecular:453.53SNS-314
CAS:SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.Fórmula:C18H15ClN6OS2Pureza:98%Forma y color:SolidPeso molecular:430.93CW-069
CAS:CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Forma y color:SolidPeso molecular:500.33Ref: TM-T6209
1mg40,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg118,00€25mg205,00€50mg290,00€100mg409,00€500mg888,00€THZ1 Hydrochloride
THZ1 Hydrochloride: selective covalent CDK7 inhibitor, IC50 of 3.2 nM; affects CDK12/13 & lowers MYC expression.Fórmula:C31H29Cl2N7O2Forma y color:SolidPeso molecular:602.51Chroman 1 dihydrochloride
Chroman 1 dihydrochloride: potent ROCK2 inhibitor (IC50: 1 pM), also affects ROCK1 (52 pM) and MRCK (150 nM).Fórmula:C24H30Cl2N4O4Forma y color:SolidPeso molecular:509.43Dalpiciclib hydrochloride
Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.Fórmula:C25H31ClN6O2Forma y color:SolidPeso molecular:483.01LIMK-IN-22j
CAS:LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.Fórmula:C20H21BrN8Pureza:99.165%Forma y color:SolidPeso molecular:453.34Trimethoprim sulfate
CAS:Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.Fórmula:C28H38N8O10SForma y color:SolidPeso molecular:678.72CX-5461 dihydrochloride
CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).Fórmula:C27H29Cl2N7O2SForma y color:SolidPeso molecular:586.54Folinic acid calcium hydrate
CAS:Folinic acid (Leucovorin) calcium hydrate is a biofolic acid often used as a rescue agent with methotrexate (MTX) to reduce MTX-induced toxicity.Fórmula:C20H23CaN7O8Forma y color:SolidPeso molecular:529.523Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Fórmula:C25H21FN6O2SPureza:96.17% - 97.49%Forma y color:SolidPeso molecular:488.54Simeprevir sodium
CAS:Simeprevir is a drug for the treatment and cure of hepatitis C.Fórmula:C38H46N5NaO7S2Pureza:98%Forma y color:SolidPeso molecular:771.92APTO-253 HCl
CAS:APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.Fórmula:C22H15ClFN5Forma y color:SolidPeso molecular:403.84HA-100 hydrochloride
CAS:HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.Fórmula:C13H16ClN3O2SForma y color:SolidPeso molecular:313.8LY3143921
CAS:LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].Fórmula:C16H12FN5OForma y color:SolidPeso molecular:309.3JSH-150
CAS:JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).Fórmula:C24H33ClN6O2SPureza:99.96% - 99.96%Forma y color:SolidPeso molecular:505.08LY2880070
CAS:LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.Fórmula:C19H23N7O2Pureza:99.77%Forma y color:SolidPeso molecular:381.43GNF2133 hydrochloride
CAS:GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.Fórmula:C24H31ClN6O2Forma y color:SolidPeso molecular:471.0HMN-214
CAS:HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.Fórmula:C22H20N2O5SPureza:98% - >99.99%Forma y color:SolidPeso molecular:424.47Ref: TM-T2438
1mg38,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg207,00€50mg333,00€100mg477,00€500mg1.063,00€TAK-960
CAS:TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.Fórmula:C27H34F3N7O3Pureza:97.06%Forma y color:SolidPeso molecular:561.6Ref: TM-T7200
1mg60,00€2mg85,00€5mg114,00€10mg161,00€1mL*10mM (DMSO)161,00€25mg279,00€50mg464,00€100mg672,00€Cyclo(-RGDfK) TFA
CAS:Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).Fórmula:C29H42F3N9O9Pureza:98.99% - 99.54%Forma y color:SolidPeso molecular:717.69Seliciclib
CAS:Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.Fórmula:C19H26N6OPureza:97.15% - 99.89%Forma y color:White To Off-White SolidPeso molecular:354.45InhA-IN-2
CAS:N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.Fórmula:C16H15ClN2O2S2Pureza:98.4%Forma y color:SolidPeso molecular:366.89Ref: TM-T9734
1mg93,00€5mg182,00€1mL*10mM (DMSO)187,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.071,00€360A
CAS:360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
Fórmula:C27H23N5O2Pureza:98.68%Forma y color:SolidPeso molecular:449.5TH5487
CAS:TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)Fórmula:C19H18BrIN4O2Pureza:98.38% - 98.73%Forma y color:SolidPeso molecular:541.18Ref: TM-T8119
1mg46,00€2mg59,00€5mg88,00€1mL*10mM (DMSO)105,00€10mg152,00€25mg288,00€50mg520,00€100mg750,00€500mg1.521,00€Mogroside I E1
CAS:Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.Fórmula:C36H62O9Pureza:98.62% - 99.71%Forma y color:SolidPeso molecular:638.87Protein kinase inhibitor 6
CAS:Protein kinase inhibitor 6 is a protein kinase inhibitor.Fórmula:C13H9FN2SPureza:98.01%Forma y color:SolidPeso molecular:244.29Ref: TM-T9779
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg86,00€25mg163,00€50mg222,00€100mg324,00€200mg440,00€AZD-5438
CAS:AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Fórmula:C18H21N5O2SPureza:99.73% - 99.87%Forma y color:SolidPeso molecular:371.46PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Fórmula:C20H27F2N5O4SPureza:98.77% - 99.55%Forma y color:SolidPeso molecular:471.52Ref: TM-T8463
1mg54,00€5mg114,00€1mL*10mM (DMSO)118,00€10mg178,00€25mg334,00€50mg557,00€100mg888,00€200mg1.198,00€2'-Deoxy-2'-fluorocytidine
CAS:2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.Fórmula:C9H12FN3O4Pureza:99.90%Forma y color:White Or Almost White Crystalline PowderPeso molecular:245.21GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Fórmula:C29H37N7O5SPureza:99.4% - 99.70%Forma y color:SolidPeso molecular:595.71Ref: TM-T4259
1mg44,00€5mg98,00€1mL*10mM (DMSO)129,00€10mg144,00€25mg236,00€50mg350,00€100mg522,00€500mg1.134,00€Roniciclib
CAS:Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.Fórmula:C18H21F3N4O3SPureza:98% - 98.63%Forma y color:SolidPeso molecular:430.44SCH900776
CAS:SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.Fórmula:C15H18BrN7Pureza:96.69% - 99.6%Forma y color:SolidPeso molecular:376.25Eprociclovir potassium
CAS:Eprociclovir potassium, 15x stronger than acyclovir, inhibits EHV1 and human herpesviruses, also treats herpetic keratitis effectively with eyedrops.Fórmula:C11H15KN5O3Forma y color:SolidPeso molecular:304.37DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Fórmula:C41H49N4O9PPureza:98.28%Forma y color:SolidPeso molecular:772.82SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFórmula:C15H19Br2ClN4Pureza:98.13% - 98.47%Forma y color:SolidPeso molecular:450.6Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFórmula:C24H26N4O5SPureza:99.00% - 99.86%Forma y color:SolidPeso molecular:482.55Ref: TM-T4226
1mg34,00€1mL*10mM (DMSO)52,00€5mg71,00€10mg92,00€25mg152,00€50mg222,00€100mg334,00€200mg494,00€Dalpiciclib
CAS:Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.
Fórmula:C25H30N6O2Pureza:99.69%Forma y color:SolidPeso molecular:446.54CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFórmula:C18H20N6OSPureza:97.36% - 97.59%Forma y color:SolidPeso molecular:368.46Acelarin
CAS:Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Fórmula:C25H27F2N4O8PPureza:99.26%Forma y color:SolidPeso molecular:580.47POL1-IN-1
CAS:POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。
Fórmula:C21H20N6Pureza:98% - 98.01%Forma y color:SolidPeso molecular:356.42LXW7
CAS:LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Fórmula:C29H48N12O12S2Pureza:>99.99%Forma y color:SolidPeso molecular:820.89BMS-3
CAS:BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.Fórmula:C17H12Cl2F2N4OSPureza:99.31% - 99.81%Forma y color:SolidPeso molecular:429.276-O-Methyl Guanosine
CAS:6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.Fórmula:C11H15N5O5Pureza:97.5%Forma y color:SolidPeso molecular:297.27Ispinesib
CAS:Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic
Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Forma y color:SolidPeso molecular:517.06Saccharin 1-methylimidazole
CAS:Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.Fórmula:C7H5NO3S·C4H6N2Pureza:98.21%Forma y color:SolidPeso molecular:265.29AZD-5597
CAS:AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent
Fórmula:C23H28FN7OPureza:98.01%Forma y color:SolidPeso molecular:437.51
