Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(269 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3904 productos de "Ciclo celular / Checkpoint"
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PF-4950834
CAS:PF-4950834, a ATP-competitive, selective Rho kinase inhibitor, provides therapeutic benefits in chronic inflammatory diseases.Fórmula:C21H19N3O2Pureza:98%Forma y color:SolidPeso molecular:345.39PV-1115
CAS:PV-1115 is an effective and highly selective inhibitor of the Chk2.Fórmula:C20H19N7O3Pureza:98%Forma y color:SolidPeso molecular:405.41HIV-1 inhibitor-43
CAS:HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.Fórmula:C24H21ClN2O4SForma y color:SolidPeso molecular:468.95SLK/STK10-IN-1
CAS:SLK/STK10-IN-1 is a selective and potent inhibitor of SLK and STK10 with potential antitumor activity.Fórmula:C17H13ClN2O3Pureza:99.34%Forma y color:SolidPeso molecular:328.75(Rac)-Managlinat dialanetil
CAS:Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.Fórmula:C21H33N4O6PSPureza:98.52%Forma y color:SolidPeso molecular:500.55DHODH-IN-12
CAS:DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Fórmula:C10H9N3O2Pureza:99.53%Forma y color:SolidPeso molecular:203.2Ref: TM-T11021
1mg73,00€5mg149,00€10mg213,00€25mg319,00€50mg447,00€100mg610,00€200mg823,00€1mL*10mM (DMSO)122,00€CGP 53353
CAS:CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Fórmula:C20H13F2N3O2Pureza:98.11%Forma y color:SolidPeso molecular:365.33JFN05510
CAS:Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.Fórmula:C50H68N7O9PSiForma y color:SolidPeso molecular:970.18R-82913
CAS:R-82913 blocks RNA-polymerase, lowers mouse DOI-head-shakes, halts 13 HIV-1 strains with 0.15µM IC50, beats AZT-TP by 20x; ineffective on HIV-2.Fórmula:C16H20ClN3SForma y color:SolidPeso molecular:321.87UCK2 Inhibitor-1
CAS:UCK2 Inhibitor-1 is a non-competitive UCK2 inhibitor with an IC 50 of 4.7 µM .Fórmula:C27H21N3O4SForma y color:SolidPeso molecular:483.54RTC14
CAS:RTC14 induces PTC readthrough, restoring dystrophin and aiding muscle function in Duchenne model mice.Fórmula:C17H18N2O3Forma y color:SolidPeso molecular:298.34Epiroprim
CAS:Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor with antibacterial activity, inhibiting Staphylococcus and Streptococcus.Fórmula:C19H23N5O2Pureza:99.68% - >99.99%Forma y color:SolidPeso molecular:353.4212(S)-HpETE
CAS:12(S)-HpETE activates human blood leukocyte 5-LOE and mediates induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction.Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47Fosteabine
CAS:Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.Fórmula:C27H50N3O8PPureza:98%Forma y color:SolidPeso molecular:575.67CBL 0100 free base
CAS:CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Fórmula:C24H26N2O2Pureza:98.18% - 98.86%Forma y color:SolidPeso molecular:374.48β-catenin-IN-3
CAS:β-catenin-IN-3 is a selective and potent β-catenin inhibitor (KD: 54.96 nM) that targets a cryptic regulatory site of β-catenin and significantly reduces theFórmula:C19H20Br2N2OSForma y color:SolidPeso molecular:484.25APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Fórmula:C22H28N6O4Pureza:99.8%Forma y color:SolidPeso molecular:440.5Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Fórmula:C22H18ClN5O3Forma y color:SolidPeso molecular:435.86LSN 3213128
CAS:LSN 3213128: a potent oral antifolate targeting AICARFT with IC50s of 16 nM (enzyme) and 19 nM (cells), offers anti-tumor effects.Fórmula:C17H16FN3O4S2Forma y color:SolidPeso molecular:409.45Myt1-IN-1
CAS:Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].Fórmula:C16H15ClN4O2Forma y color:SolidPeso molecular:330.77CCT245737(S)
CAS:CCT245737(S) is a highly selective oral checkpoint kinase 1 (CHK1) inhibitor.Fórmula:C16H16F3N7OForma y color:SolidPeso molecular:379.34Photoregulin3
CAS:Photoregulin3 is a inhibitor of rod photoreceptor gene expression, potentially though Nr2e3 modulation.Fórmula:C22H23N3O3Forma y color:SolidPeso molecular:377.44AZD7762 HCl
CAS:AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.Fórmula:C17H20ClFN4O2SPureza:98%Forma y color:SolidPeso molecular:398.88CDK-IN-10
CAS:CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.Fórmula:C18H18N4O2Pureza:97.07%Forma y color:SolidPeso molecular:322.36VPC-70619
CAS:VPC-70619: Oral, selective N-Myc inhibitor; blocks cancer growth by hindering N-Myc-Max/DNA binding; well-absorbed.Fórmula:C16H8ClF3N4OForma y color:SolidPeso molecular:364.71CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Fórmula:C16H18N2O7SPureza:99.95%Forma y color:SolidPeso molecular:382.39BAY-958
CAS:BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.Fórmula:C17H16FN5O3SPureza:98%Forma y color:SolidPeso molecular:389.4Erythromycin hydrochloride
CAS:Erythromycin hydrochloride is an inhibitor of protein translation and mammalian mRNA splicing. It inhibits growth of gram negative and gram positiove bacteria.Fórmula:C37H68ClNO13Forma y color:SolidPeso molecular:770.39WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Fórmula:C13H15BrCl2N2O4SPureza:98.09%Forma y color:SolidPeso molecular:446.14Ref: TM-T73295
1mg71,00€5mg152,00€10mg236,00€25mg485,00€50mg782,00€100mg1.305,00€1mL*10mM (DMSO)167,00€Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Fórmula:C30H33Cl4N3O4Pureza:98%Forma y color:SolidPeso molecular:641.41BAP1-IN-1
CAS:BAP1-IN-1 is an inhibitor of the catalytic activity of BRCA1-associated protein 1 (BAP1), which is related to cancer and can be used to study cancer.Fórmula:C18H16N2O2Pureza:98.11%Forma y color:SolidPeso molecular:292.33BAY-707 acetate
CAS:BAY-707: potent, selective MTH1 inhibitor with excellent engagement and pharmacokinetics but no anticancer efficacy alone or combined.Fórmula:C17H24N4O4Forma y color:SolidPeso molecular:348.18TIBI
CAS:TIBI is an ATP-competitive Rio1 inhibitor that acts in a similar manner to fungamycin and enhances the thermal stability of the enzyme.Fórmula:C7H2I4N2Pureza:>99.99%Forma y color:SolidPeso molecular:621.72Ametantrone Acetate
CAS:Ametantrone Acetate is a topoisomerase II inhibitor of anthrapyrazole family, which can lead to DNA covalent crosslinking.Fórmula:C24H32N4O6Forma y color:SolidPeso molecular:472.542Mycro1
CAS:Mycro1 is an inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max.Fórmula:C20H15F3N4O2SForma y color:SolidPeso molecular:432.42RECQL5-IN-1
CAS:RECQL5-IN-1, an oral RECQL5 inhibitor (IC50 46.3 nM), targets enzyme/non-enzyme domains, useful in breast cancer research.Fórmula:C25H18F6N4O2SForma y color:SolidPeso molecular:552.49Pyrazofurin
CAS:Pyrazofurin, a pyrimidine analogue, blocks cell growth and DNA synthesis by targeting UMP synthase & orotate-phosphoribosyltransferase (IC50: 0.06-0.37 μM).Fórmula:C9H13N3O6Pureza:98%Forma y color:SolidPeso molecular:259.22IPR-803
CAS:IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.Fórmula:C27H23N3O4Pureza:95%Forma y color:SolidPeso molecular:453.49GR 144053 trihydrochloride
CAS:platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFórmula:C18H30Cl3N5O2Pureza:98%Forma y color:SolidPeso molecular:454.82CFI-400437
CAS:CFI-400437 is an ATP-competitive PLK4 inhibitor (IC50: 0.6 nM) and is an indolequinone derivative.Fórmula:C29H28N6O2Forma y color:SolidPeso molecular:492.57Cdc7-IN-9
CAS:Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].Fórmula:C15H17N5OSForma y color:SolidPeso molecular:315.39UR-2922
CAS:UR-2922: Oral GPIIb/IIIa blocker with <1 nM affinity, slow 90 min k(off), no LIBS or prothrombotic effects.Fórmula:C25H25N7O6Pureza:98%Forma y color:SolidPeso molecular:519.51SAR156497
CAS:SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Fórmula:C27H24N4O4Forma y color:SolidPeso molecular:468.5SR7826
CAS:SR7826 is a selective LIMK inhibitor.Fórmula:C22H21N5O2Pureza:98%Forma y color:SolidPeso molecular:387.43GSK3182571
CAS:GSK3182571 is a non-speci c kinase inhibitor[1].Fórmula:C25H31ClN8OForma y color:SolidPeso molecular:495.02HOI-07
CAS:HOI-07 is a specific Aurora B inhibitor.Fórmula:C19H13NO4Forma y color:SolidPeso molecular:319.31Chlorozotocin
CAS:Chlorozotocin is a nitrosourea. It is used for cancer therapy.Fórmula:C9H16ClN3O7Forma y color:SolidPeso molecular:313.69IS-741 calcium
CAS:IS-741 calcium is a phospholipase A2 inhibitor.Fórmula:C30H38CaF6N6O6S2Forma y color:SolidPeso molecular:796.8610-Deazaaminopterin
CAS:10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.Fórmula:C20H21N7O5Forma y color:SolidPeso molecular:439.42CFI-400936
CAS:CFI-400936: potent TTK inhibitor (IC50=3.6nM), potential anticancer, active in cell assays, selective vs. human kinases.Fórmula:C25H27N5O3SForma y color:SolidPeso molecular:477.58Tripolin A
CAS:Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)Fórmula:C15H11NO3Pureza:98%Forma y color:SolidPeso molecular:253.25IS-741 potassium
CAS:IS-741 potassium is a phospholipase A2 inhibitor.Fórmula:C15H19F3KN3O3SForma y color:SolidPeso molecular:417.49Teloxantrone
CAS:Teloxantrone: an anthrapyrazole antibiotic inhibiting DNA replication, RNA/protein synthesis by interacting with DNA and topoisomerase II.Fórmula:C21H25N5O4Forma y color:SolidPeso molecular:411.455-OHdU
CAS:5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.Fórmula:C9H12N2O6Pureza:99.5%Forma y color:SolidPeso molecular:244.2Ref: TM-T19152
1mg38,00€5mg80,00€10mg111,00€25mg202,00€50mg305,00€100mg432,00€200mg622,00€1mL*10mM (DMSO)88,00€Cdc7-IN-4
CAS:Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.Fórmula:C22H24F3N5O4Pureza:98%Forma y color:SolidPeso molecular:479.45Valategrast
CAS:Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.Fórmula:C30H32Cl3N3O4Pureza:98%Forma y color:SolidPeso molecular:604.95SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Fórmula:C15H14ClN3OSPureza:98.52%Forma y color:SolidPeso molecular:319.81Ref: TM-T28848
1mg63,00€5mg137,00€10mg215,00€25mg439,00€50mg708,00€100mg1.144,00€1mL*10mM (DMSO)145,00€CB 3731
CAS:CB 3731 is used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase.Fórmula:C23H24FN5O6Forma y color:SolidPeso molecular:485.46AG-012986
CAS:AG-012986: a selective CDK inhibitor with in vitro and in vivo antitumor effects; low IC50 in 14/18 cancer cell types; CAS# 486414-35-1.Fórmula:C22H23F2N5O2SForma y color:SolidPeso molecular:459.51AM-5308
CAS:AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.Fórmula:C26H35N5O5SPureza:98.06% - 99.58%Forma y color:SolidPeso molecular:529.65EMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Fórmula:C25H31F3N4O2Pureza:98%Forma y color:SolidPeso molecular:476.53AP-1/NF-κB activation inhibitor 1
CAS:AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basalFórmula:C13H11F3N4O4Pureza:99.52% - 99.91%Forma y color:SolidPeso molecular:344.25Ref: TM-T9656
1mg70,00€2mg90,00€5mg152,00€10mg205,00€25mg334,00€50mg497,00€100mg692,00€500mg1.404,00€1mL*10mM (DMSO)166,00€2-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.
Fórmula:C5H4FN5Pureza:98.84% - 99.62%Forma y color:White To Light Yellow Crystal PowderPeso molecular:153.12XMD-17-51
CAS:XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.Fórmula:C21H24N8OPureza:99.04%Forma y color:SoildPeso molecular:404.47Aloisine B
CAS:Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.Fórmula:C15H14ClN3Pureza:95.15%Forma y color:SolidPeso molecular:271.74BMS-986463
CAS:BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD). BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC).Fórmula:C32H33FN4O5Forma y color:SolidPeso molecular:572.635-Ethynyluridine
CAS:5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.Fórmula:C11H12N2O6Pureza:99.78%Forma y color:SolidPeso molecular:268.22Ref: TM-T36971
5mg49,00€10mg84,00€25mg138,00€50mg236,00€100mg344,00€200mg515,00€1mL*10mM (DMSO)54,00€DHODH-IN-4
CAS:DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Fórmula:C17H12Cl2N2O2Pureza:99.34%Forma y color:SolidPeso molecular:347.2Ref: TM-T11027
1mg109,00€2mg163,00€5mg243,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mg2.035,00€1mL*10mM (DMSO)248,00€SPC-839
CAS:SPC-839 is an IKK-2 Inhibitor with oral activity.Fórmula:C18H14N4O3SForma y color:SolidPeso molecular:366.39ARN22089
CAS:ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.Fórmula:C23H27N5Pureza:98.37%Forma y color:SolidPeso molecular:373.49Ref: TM-T85727
1mg109,00€5mg260,00€10mg385,00€25mg647,00€50mg964,00€100mg1.431,00€200mg1.963,00€1mL*10mM (DMSO)286,00€IXA6
CAS:IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.Fórmula:C22H20ClN3O3SPureza:98.63%Forma y color:SolidPeso molecular:441.93MTH1-IN-2
CAS:MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.Fórmula:C24H27N3O5SPureza:98%Forma y color:SolidPeso molecular:469.55SB-772077B dihydrochloride
CAS:SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).Fórmula:C15H20Cl2N8O2Pureza:98%Forma y color:SolidPeso molecular:415.28H-1152
CAS:H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).Fórmula:C16H21N3O2SPureza:98%Forma y color:SolidPeso molecular:319.42Mequindox
CAS:Mequindox is an antimicrobial agent [1]. Mequindox, as an inhibitor of DNA synthesis, induces genotoxicity and carcinogenicity in mice [2].Fórmula:C11H10N2O3Forma y color:SolidPeso molecular:218.21Phen-DC3
CAS:Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).Fórmula:C34H26N6O2Pureza:98%Forma y color:SolidPeso molecular:550.61BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Fórmula:C26H19Cl2N5O4Pureza:98.87%Forma y color:SolidPeso molecular:536.37Ref: TM-T14676
1mg108,00€5mg264,00€10mg371,00€25mg665,00€50mg874,00€100mg1.063,00€200mg1.423,00€1mL*10mM (DMSO)311,00€Antitumor agent-84
Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.Fórmula:C24H31N7Forma y color:SolidPeso molecular:417.55TCS 2312
CAS:checkpoint kinase 1 (chk1) inhibitorFórmula:C25H24N4O2Pureza:98%Forma y color:SolidPeso molecular:412.48CDK8-IN-4
CAS:CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).Fórmula:C20H18N4OForma y color:SolidPeso molecular:330.38Trimetrexate
CAS:Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase.Fórmula:C19H23N5O3Pureza:98%Forma y color:SolidPeso molecular:369.42IRE1α kinase-IN-3
CAS:IRE1α kinase-IN-3 is a potent, ATP-competitive inhibitor of IRE1α (Ki: 480 nM).Fórmula:C29H32N6O3SForma y color:SolidPeso molecular:544.67Laflunimus
CAS:Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.Fórmula:C15H13F3N2O2Pureza:99.86%Forma y color:SolidPeso molecular:310.27Integrin-IN-2
CAS:Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.Fórmula:C27H30N4O3Pureza:98%Forma y color:SolidPeso molecular:458.55360A iodide
CAS:360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).Fórmula:C27H23I2N5O2Pureza:98%Forma y color:SolidPeso molecular:703.31CDK12-IN-3
CAS:CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.Fórmula:C23H28F2N8OPureza:99.85%Forma y color:SolidPeso molecular:470.52Ref: TM-T14990
1mg101,00€5mg245,00€10mg401,00€25mg842,00€50mg1.701,00€100mg2.250,00€1mL*10mM (DMSO)254,00€NSC 625987
CAS:NSC 625987, Selective CDK4 inhibitor (IC50=0.2 μM), >500-fold selectivity over CDK2, used for p16-associated tumor studies.Fórmula:C15H13NO2SPureza:98%Forma y color:SolidPeso molecular:271.33Ref: TM-T23092
1mg63,00€2mg105,00€5mg137,00€10mgA consultar25mgA consultar50mg595,00€100mg893,00€1mL*10mM (DMSO)A consultarCdc7-IN-1
CAS:Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.Fórmula:C21H16ClN3O4Forma y color:SolidPeso molecular:409.82Chlorasquin
CAS:Chlorasquin is a dihydrofolate reductase inhibitor.Fórmula:C20H19ClN6O5Pureza:98%Forma y color:SolidPeso molecular:458.86UR-3216
CAS:UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.Fórmula:C27H29N7O7Pureza:98%Forma y color:SolidPeso molecular:563.56Nucleoside-Analog-2
CAS:Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.Fórmula:C9H11N5O6Pureza:98%Forma y color:SolidPeso molecular:285.21CLK1/2-IN-3
CAS:CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.Fórmula:C21H21N5O2Pureza:99.04%Forma y color:SolidPeso molecular:375.42USP28-IN-3
CAS:USP28-IN-3 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.Fórmula:C23H20Cl2N2O3SPureza:99.92%Forma y color:SolidPeso molecular:475.39CDK2-IN-13
CAS:CDK2-IN-13: Potent CDK2 inhibitor, arrests cell cycle, induces apoptosis, IC50=12 µM, used in cancer research.Fórmula:C13H12ClN5Forma y color:SoildPeso molecular:273.72CDK12-IN-E9
CAS:CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.Fórmula:C24H30N6O2Forma y color:SolidPeso molecular:434.53SRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Fórmula:C27H21FN2O3SPureza:98%Forma y color:SolidPeso molecular:472.53AS2863619 free base
CAS:AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.Fórmula:C16H12N8OForma y color:SolidPeso molecular:332.32USP28-IN-4
CAS:USP28-IN-4 is a USP28 inhibitor with anticancer activity that dose-dependently down-regulates cellular levels of c-Myc via the ubiquitin-proteasome system.Fórmula:C22H18Cl2N2O3SPureza:98.48%Forma y color:SolidPeso molecular:461.36FT827
CAS:FT827 is a covalent inhibitor of USP7 that targets the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research.Fórmula:C27H28N6O5SPureza:98.76%Forma y color:SolidPeso molecular:548.61
