Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(269 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3904 productos de "Ciclo celular / Checkpoint"
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XVA143
CAS:XVA143 is an integrin α/β I-like allosteric antagonist, inhibits LFA-1 (αLβ2 integrin)-dependent firm adhesion, induces extended conformations of integrins.Fórmula:C25H21Cl2N3O8Pureza:99.94%Forma y color:SolidPeso molecular:562.36IRE1α kinase-IN-7
CAS:IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmicFórmula:C28H25F3N6OForma y color:SolidPeso molecular:518.53Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Fórmula:C13H11ClFN5Forma y color:SolidPeso molecular:291.71HBV-IN-4
CAS:HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.Fórmula:C24H19ClFN5O3Forma y color:SolidPeso molecular:479.89Cylindrospermopsin
CAS:Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.Fórmula:C15H21N5O7SForma y color:SolidPeso molecular:415.42MDK6204
CAS:MDK6204 is a selective inhibitor of CLK1 and CLK2.Fórmula:C20H20N6OPureza:98%Forma y color:SolidPeso molecular:360.41Zalunfiban
CAS:RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.Fórmula:C16H18N8O2SForma y color:SolidPeso molecular:386.43MLAF50
CAS:MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.Fórmula:C15H12I2O4Forma y color:SolidPeso molecular:510.06Cdc7-IN-15
CAS:Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].Fórmula:C12H14N4OSForma y color:SolidPeso molecular:262.33Syntelin
CAS:Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.Fórmula:C21H20N6O2S3Forma y color:SolidPeso molecular:484.62DNA Gyrase-IN-5
CAS:DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.Fórmula:C25H15BrClN5Forma y color:SolidPeso molecular:500.78CP681301
CAS:CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.Fórmula:C17H22N4OForma y color:SolidPeso molecular:298.38DNA Gyrase-IN-2
CAS:DNA Gyrase-IN-2 inhibits E. coli (IC50: 3.29-10.49 μM) and M. tuberculosis (IC50: 4.41-5.61 μM) COX, has antibacterial properties.Fórmula:C24H24N8OS2Forma y color:SolidPeso molecular:504.63BSJ-01-175
CAS:BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.Fórmula:C30H33ClN6O2Forma y color:SolidPeso molecular:545.08DENV-IN-7
CAS:DENV-IN-7, a flavone analog, inhibits dengue virus at 70 nM EC50 with low toxicity to normal cells.Fórmula:C24H22O8Forma y color:SolidPeso molecular:438.43P1788
CAS:P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].Fórmula:C15H17NO3Forma y color:SolidPeso molecular:259.3Antibacterial agent 89
CAS:Antibacterial agent 89 blocks bacterial transcription and clostridial cytotoxins, inhibiting β'CH-σ interactions.Fórmula:C21H10Cl2F3NO5SForma y color:SolidPeso molecular:516.27CDK7-IN-15
CAS:CDK7-IN-15 (Compound 8) is an effective CDK7 inhibitor for studying cancers associated with transcriptional dysregulation.Fórmula:C21H24F4N6OSPureza:99.27%Forma y color:SolidPeso molecular:484.51Indirubin-3'-monoxime-5-sulphonic acid
CAS:Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.Fórmula:C16H11N3O5SPureza:98%Forma y color:SolidPeso molecular:357.34CDK7-IN-13
CAS:CDK7-IN-13 (compound 1) is an effective CDK7 inhibitor for investigating cancers associated with transcriptional dysregulation.Fórmula:C20H23F3N6OSPureza:99.22%Forma y color:SolidPeso molecular:452.55,10-Dideazafolic acid
CAS:5,10-Dideazafolic acid is an antileukemic drug.Fórmula:C21H21N5O6Forma y color:SolidPeso molecular:439.428RK64
CAS:8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .Fórmula:C14H16N8O2SForma y color:SolidPeso molecular:360.4Chrysotobibenzyl
CAS:Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.Fórmula:C19H24O5Forma y color:SolidPeso molecular:332.39Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Fórmula:C7H4O3S2Pureza:98.50%Forma y color:White To Off-White PowderPeso molecular:200.23Integrin modulator 1
CAS:Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.Fórmula:C13H14N2O4Pureza:99.61%Forma y color:SolidPeso molecular:262.26CDK7-IN-20
CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.Fórmula:C30H26N6O3Forma y color:SolidPeso molecular:518.57c-Myc inhibitor 9
CAS:c-Myc inhibitor 9 (compound 332) with logEC50 ≥6, suppresses tumors in mice, useful for cancer research.Fórmula:C27H31N5OSForma y color:SolidPeso molecular:473.63BMS-587101
CAS:BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.Fórmula:C26H20Cl2N4O4SForma y color:SolidPeso molecular:555.43ML372
CAS:ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.Fórmula:C18H20N2O4SForma y color:SolidPeso molecular:360.43ERCC1-XPF-IN-1
CAS:ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.Fórmula:C28H32ClN5O2Forma y color:SolidPeso molecular:506.04CH-1504
CAS:CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.Fórmula:C23H23N5O5Forma y color:SolidPeso molecular:449.46MtTMPK-IN-6
CAS:MtTMPK-IN-6 inhibits M. tuberculosis thymidylate kinase with IC50 of 29 μM, promising for TB research.Fórmula:C23H25N3O3Forma y color:SolidPeso molecular:391.46FINDY
CAS:FINDY selectively inhibits DYRK1A at 35 μM IC50, blocking Ser97 autophosphorylation, useful for neurological disorder research.Fórmula:C16H17NO2S2SiForma y color:SolidPeso molecular:347.53MMV688844
CAS:MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.Fórmula:C23H25ClN4O2Forma y color:SolidPeso molecular:424.92IACS-4759
CAS:IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.Fórmula:C10H17N3O2Forma y color:SolidPeso molecular:211.26Sibrafiban
CAS:Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.Fórmula:C20H28N4O6Forma y color:SolidPeso molecular:420.46CB 3717
CAS:CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.Fórmula:C24H23N5O6Forma y color:SolidPeso molecular:477.47LIMK1 inhibitor BMS-4
CAS:BMS-4 is a LIMK inhibitor targeting LIMK1/2, reduces cofilin phosphorylation, noncytotoxic to A549 cells.Fórmula:C23H23N7O2SForma y color:SolidPeso molecular:461.54CDK7-IN-10
CAS:CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)Fórmula:C29H35N7O3Forma y color:SolidPeso molecular:529.63CDK7-IN-16
CAS:CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.Fórmula:C19H21F3N6O2SForma y color:SolidPeso molecular:454.47HBV-IN-15
CAS:HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.Fórmula:C24H23ClO6Forma y color:SolidPeso molecular:442.89DHX9-IN-1
CAS:DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].Fórmula:C21H21F2N5O3SForma y color:SolidPeso molecular:461.49Ref: TM-T82569
1mg205,00€5mg528,00€10mg782,00€25mg1.161,00€50mg1.558,00€100mg2.322,00€1mL*10mM (DMSO)537,00€Antitumor agent-85
Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.Fórmula:C24H33N7Forma y color:SolidPeso molecular:419.57VE-465
CAS:VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.Fórmula:C22H28N8OSForma y color:SolidPeso molecular:452.582'-Deoxy-L-guanosine
CAS:2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death.Fórmula:C10H13N5O4Forma y color:SolidPeso molecular:267.24CDK7-IN-8
CAS:CDK7-IN-8 is a potent inhibitor of CDK7 (IC50: 54.29 nM) and exhibits inhibitory activity against several cancer cells and in vivo tumor models.Fórmula:C25H38N8O3Forma y color:SolidPeso molecular:498.62Mps1-IN-4
CAS:Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.Fórmula:C26H31F3N6O2Forma y color:SolidPeso molecular:516.56BDM44768
CAS:BDM44768 is an insulin-degrading enzyme (IDE) inhibitor that acts by inducing glucose intolerance.Fórmula:C24H22FN5O3Forma y color:SolidPeso molecular:447.46DENV-IN-4
CAS:DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.Fórmula:C28H32N4O4SiForma y color:SolidPeso molecular:516.6614α-Demethylase/DNA Gyrase-IN-2
CAS:14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.Fórmula:C24H22N4O4Forma y color:SolidPeso molecular:430.46NSC 109555 ditosylate
CAS:Chk2 inhibitor,ATP-competitiveFórmula:C26H32N10O4SPureza:98%Forma y color:SolidPeso molecular:580.66Indirubin-5-sulfonate
CAS:Indirubin-5-sulfonate inhibits GSK-3β & CDKs with IC50: 55/35/150/300/65 nM for CDK1/B, 2/A&E, 4/D1, 5/p35.Fórmula:C16H10N2O5SPureza:98%Forma y color:SolidPeso molecular:342.33Mps-BAY2b
CAS:Mps-BAY2b is a novel MPS1 inhibitor.Fórmula:C20H23N5OForma y color:SolidPeso molecular:349.43Werner syndrome RecQ helicase-IN-3
CAS:Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.Fórmula:C31H30ClF3N8O5Forma y color:SolidPeso molecular:687.07CDK9-IN-14
CAS:CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.Fórmula:C21H23F2N3O4Forma y color:SolidPeso molecular:419.42IRE1α kinase-IN-9
CAS:IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.Fórmula:C24H24N2O6Pureza:98%Forma y color:SolidPeso molecular:436.46Crisnatol mesylate
CAS:Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.Fórmula:C24H27NO5SForma y color:SolidPeso molecular:441.54CDK7-IN-12
CAS:CDK7-IN-12 inhibits CDK7 to control transcription and cell cycle, halting tumor growth in vitro/vivo with cancer research potential.Fórmula:C20H19F3N6Forma y color:SolidPeso molecular:400.4HBV-IN-16
CAS:HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).Fórmula:C22H20ClNO4Forma y color:SolidPeso molecular:397.85CDK4/6-IN-9
CAS:CDK4/6-IN-9 selectively inhibits CDK4/6 (IC50: 905 nM); potential for MM research.Fórmula:C22H23FN8Forma y color:SolidPeso molecular:418.47DAP-81
CAS:DAP-81, a diaminopyrimidine, inhibits Plk1 (IC50: 0.9 nM), disrupts microtubules, causes monopolar spindles; in preclinical studies.Fórmula:C25H20N6O4Forma y color:SolidPeso molecular:468.46Cdc7-IN-13
CAS:Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].Fórmula:C18H20N4O2SForma y color:SolidPeso molecular:356.44Ulecaciclib
CAS:Ulecaciclib: oral, BBB-permeable CDK inhibitor; favorable pharmacokinetics; ki: 0.62 μM (CDK2/A), 3 nM (CDK6/D3), 0.2 nM (CDK4/D1), 0.63 μM (CDK7/H).Fórmula:C25H33FN8SForma y color:SolidPeso molecular:496.65FAK/aurora kinase-IN-1
CAS:FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Fórmula:C23H24ClN7O3Forma y color:SolidPeso molecular:481.93Type II topoisomerase inhibitor 1
CAS:Potent E. coli DNA gyrase inhibitor (IC50: 1.7 nM), targets Asp73; weak topoisomerase IV inhibitor (IC50: 0.98 μM).Fórmula:C18H15N3O4Forma y color:SolidPeso molecular:337.33P18IN003
CAS:P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion ofFórmula:C17H16N2O3Pureza:99%Forma y color:SolidPeso molecular:296.32DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Fórmula:C17H13ClN2O2Pureza:98%Forma y color:SolidPeso molecular:312.75DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Fórmula:C24H25F4N3O3Forma y color:SolidPeso molecular:479.47LDN-209929 dihydrochloride
CAS:LDN-209929 dihydrochloride: potent haspin kinase inhibitor, 55 nM IC50, 180x more selective than DYRK2.Fórmula:C17H19Cl3N2OSForma y color:SolidPeso molecular:405.77Thiarabine
CAS:Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.Fórmula:C9H13N3O4SPureza:98%Forma y color:SolidPeso molecular:259.28JTK-101
CAS:JTK-101 is a potent and selective Tat-dependent HIV-1 replication inhibitor.Fórmula:C25H23N3O3Forma y color:SolidPeso molecular:413.47IRE1α kinase-IN-8
CAS:IRE1α kinase-IN-8, a benzoheterocyclecarboxaldehyde derivative, serves as a potent inhibitor of IRE-1α.Fórmula:C23H22N2O5Pureza:98%Forma y color:SolidPeso molecular:406.43Dihydro-5-azacytidine acetate
CAS:Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1Fórmula:C10H18N4O7Pureza:98%Forma y color:SolidPeso molecular:306.27PV-1019
CAS:PV-1019 (NSC 744039), a potent Chk2 inhibitor, has an IC50 of 24 nM and blocks Chk2 autophosphorylation and IR-induced apoptosis.Fórmula:C18H17N7O3Forma y color:SolidPeso molecular:379.37Zelpolib
CAS:Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.Fórmula:C22H21N3O5S2Pureza:98.79%Forma y color:SolidPeso molecular:471.55Aurora kinase inhibitor-9
CAS:Aurora kinase inhibitor-9 (9d) targets AURKA/B with IC50: 0.093 μM for A and 0.09 μM for B, with wide anti-proliferative effects.Fórmula:C19H17Cl2N3O4SForma y color:SolidPeso molecular:454.33(R)-DRF053 dihydrochloride
CAS:cdk/CK1 inhibitor,potent and ATP-competitiveFórmula:C23H29Cl2N7OPureza:98%Forma y color:SolidPeso molecular:490.43BI-831266
CAS:BI-831266 is a potent and selective Aurora kinase B inhibitor.Fórmula:C27H38ClN7O2Forma y color:SolidPeso molecular:528.09MK-0668
CAS:MK-0668 is a very potent and orally active very late antigen-4 antagonist.Fórmula:C31H30Cl2N6O6SForma y color:SolidPeso molecular:685.58BAY-707
CAS:BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.Fórmula:C15H20N4O2Pureza:98%Forma y color:SolidPeso molecular:288.34Protein kinase D inhibitor 1
CAS:Protein kinase D inhibitor 1 (17m) is a potent pan-PKD suppressant with IC50 of 17-35 nM, targeting cortactin phosphorylation.Fórmula:C19H21N7Forma y color:SolidPeso molecular:347.42UIAA-II-232
CAS:UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).Fórmula:C20H24FN5O3Forma y color:SolidPeso molecular:401.43L-Guanosine
CAS:L-Guanosine is the L-configuration of Guanosine. Guanosine is a purine nucleoside that has anti-herpesvirus activity [1] [2].Fórmula:C10H13N5O5Forma y color:SolidPeso molecular:283.24Atuveciclib S-Enantiomer
CAS:Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.Fórmula:C18H18FN5O2SPureza:98%Forma y color:SolidPeso molecular:387.43DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Fórmula:C26H26N4Forma y color:SolidPeso molecular:394.51Aditoprime
CAS:Aditoprime (Aditoprim) is a selective bacterial DHFR inhibitor with strong nanomolar potency and broad-spectrum antibacterial activity.Fórmula:C15H21N5O2Pureza:99.89%Forma y color:SolidPeso molecular:303.36Fozivudine tidoxil
CAS:Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C35H64N5O8PSForma y color:SolidPeso molecular:745.95Bis-Pro-5FU
CAS:Bis-Pro-5FU enhances oral uptake and safety of 5-FU, an anti-cancer drug for colorectal and pancreatic tumors.Fórmula:C10H7FN2O2Forma y color:SolidPeso molecular:206.17MSC-1186
CAS:MSC-1186 selectively inhibits SRPKs—IC50: 2.7nM (SRPK1), 81nM (SRPK2), 0.6nM (SRPK3)—for cancer research.Fórmula:C19H17ClFN7O2SForma y color:SolidPeso molecular:461.9Cdc7-IN-14
CAS:Cdc7-IN-14 (compound 82) is a potent CDC7 inhibitor with an IC50 < 1 nM, promising for cancer research.Fórmula:C18H20N4O2SForma y color:SolidPeso molecular:356.44Eg5 Inhibitor V, trans-24
CAS:Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Fórmula:C26H21N3O3Pureza:99.75%Forma y color:SolidPeso molecular:423.46Ref: TM-T11155
1mg96,00€5mg193,00€10mg289,00€25mg469,00€50mg642,00€100mg858,00€200mg1.153,00€1mL*10mM (DMSO)215,00€3,6-DMAD dihydrochloride
CAS:3,6-DMAD dihydrochloride: Potent IRE1α-XBP1s inhibitor, affects IL-6 secretion and RNase activity, used in cancer research.Fórmula:C22H33Cl2N5Forma y color:SolidPeso molecular:438.44AS-136A
CAS:AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Fórmula:C17H19F3N4O3SPureza:98.52%Forma y color:SolidPeso molecular:416.42Ref: TM-T62160
1mg215,00€5mg537,00€10mg802,00€25mg1.369,00€50mg1.783,00€100mg2.395,00€1mL*10mM (DMSO)590,00€Dyrk1A-IN-3
CAS:Dyrk1A-IN-3 is a selective DYRK1A inhibitor with an IC50 of 76 nM, useful for neurodegenerative disease research.Fórmula:C18H16N6Forma y color:SolidPeso molecular:316.36RP-6685
CAS:RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.Fórmula:C22H14F7N5OPureza:99.65%Forma y color:SoildPeso molecular:497.37Ref: TM-T60187
1mg84,00€5mg152,00€10mg219,00€25mg358,00€50mg510,00€100mg715,00€1mL*10mM (DMSO)167,00€6-Hydroxy-DOPA
CAS:6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.
Fórmula:C9H11NO5Pureza:97.78% - 97.95%Forma y color:SolidPeso molecular:213.19CF-1743
CAS:CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication.
Fórmula:C22H26N2O5Pureza:99.6% - 99.79%Forma y color:SolidPeso molecular:398.45SRX3177
CAS:SRX3177 is a novel and potent inhibitor of BRD4, PI3K and CDK.SRX3177 has potential anticancer activity.Fórmula:C31H32N6O4SPureza:99.16%Forma y color:SolidPeso molecular:584.69Ref: TM-T69742
1mg70,00€5mg150,00€10mg215,00€25mg358,00€50mg517,00€100mg707,00€1mL*10mM (DMSO)178,00€6RK73
CAS:6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).Fórmula:C13H17N5O2SPureza:99.91%Forma y color:SolidPeso molecular:307.37Ref: TM-T10188
1mg144,00€5mg298,00€10mg510,00€25mg825,00€50mg1.130,00€100mg1.510,00€500mg3.060,00€1mL*10mM (DMSO)328,00€
