Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(269 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3904 productos de "Ciclo celular / Checkpoint"
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INDY
CAS:INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.Fórmula:C12H13NO2SPureza:99.26%Forma y color:SolidPeso molecular:235.3hDHODH-IN-7
CAS:hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Fórmula:C21H23FN4OPureza:99.87%Forma y color:SolidPeso molecular:366.43Ref: TM-T11031
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)266,00€PCSK9-IN-10
CAS:PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.Fórmula:C18H23N5O4Pureza:99.06%Forma y color:SoildPeso molecular:373.41Ref: TM-T72025
2mg39,00€5mg60,00€10mg96,00€25mg170,00€50mg266,00€100mg391,00€200mg555,00€1mL*10mM (DMSO)62,00€NSC16168
CAS:NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.Fórmula:C17H15NO9S3Pureza:99.88%Forma y color:SolidPeso molecular:473.5Ref: TM-T16351
1mg60,00€5mg130,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)135,00€COH34
CAS:COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM.Fórmula:C18H15NOSPureza:99.57%Forma y color:SolidPeso molecular:293.38SB 328437
CAS:SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Fórmula:C21H18N2O5Pureza:99.54%Forma y color:SolidPeso molecular:378.38Ref: TM-T23321
1mg39,00€5mg82,00€10mg123,00€25mg250,00€50mg394,00€100mg618,00€200mg874,00€1mL*10mM (DMSO)69,00€SMN-C2
CAS:SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.Fórmula:C24H27N5O2Pureza:99.14%Forma y color:SolidPeso molecular:417.5Ref: TM-T73475
1mg105,00€5mg250,00€10mg401,00€25mg795,00€50mg982,00€100mg1.324,00€1mL*10mM (DMSO)268,00€AzddMeC
CAS:AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infectionFórmula:C10H14N6O3Pureza:97.14% - 99.62%Forma y color:SolidPeso molecular:266.26GSK2643943A
CAS:GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti-tumor efficacy.Fórmula:C17H12FN3Pureza:97.09%Forma y color:SolidPeso molecular:277.3Ref: TM-T11485
1mg39,00€2mg50,00€5mg82,00€10mg120,00€25mg236,00€50mg356,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)90,00€Anticancer agent 73
CAS:Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.Fórmula:C14H15NO4Pureza:99.56%Forma y color:SolidPeso molecular:261.27L82
CAS:L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.Fórmula:C11H8ClN5O4Pureza:98.06% - 98.91%Forma y color:SolidPeso molecular:309.67Ref: TM-T60753
5mg70,00€10mg103,00€25mg187,00€50mg298,00€100mg472,00€500mg1.026,00€1mL*10mM (DMSO)77,00€CRT0066854 hydrochloride
CAS:CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.Fórmula:C24H27Cl2N5SPureza:99.63%Forma y color:SolidPeso molecular:488.48Ref: TM-T10888
1mg57,00€5mg122,00€10mg192,00€25mg324,00€50mg459,00€100mg642,00€200mg888,00€1mL*10mM (DMSO)146,00€RP-6306
CAS:Lunresertib (RP-6306) is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 14 nM.Cost-effective and quality-assured.
Fórmula:C18H20N4O2Pureza:98.41% - 99.28%Forma y color:SolidPeso molecular:324.38TTP-8307
CAS:TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.Fórmula:C27H21FN4OPureza:98.95%Forma y color:SolidPeso molecular:436.48Ref: TM-T13221
1mg100,00€5mg236,00€10mg380,00€25mg740,00€50mg1.108,00€100mg1.791,00€200mg2.412,00€1mL*10mM (DMSO)286,00€9-Isopropylolomoucine
CAS:9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.Fórmula:C17H22N6OPureza:99.82%Forma y color:SolidPeso molecular:326.4Ref: TM-T23589
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€1mL*10mM (DMSO)607,00€hSMG-1 inhibitor 11e
CAS:hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.Fórmula:C26H27N7O3SPureza:99.89%Forma y color:SolidPeso molecular:517.6PS423
CAS:PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.Fórmula:C25H23F3O9Pureza:98.81% - 99.26%Forma y color:SolidPeso molecular:524.44YK-2-69
CAS:YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.Fórmula:C25H27FN8OSPureza:98.61% - 99.64%Forma y color:SolidPeso molecular:506.6Poloxin-2
CAS:Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.Fórmula:C16H15NO3Pureza:99.67%Forma y color:SolidPeso molecular:269.3GS-6620 PM
CAS:GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.Fórmula:C13H15N5O4Pureza:98.52% - 98.7%Forma y color:SolidPeso molecular:305.29AS 1892802
CAS:AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.Fórmula:C20H19N3O2Pureza:99.86%Forma y color:SolidPeso molecular:333.38Ref: TM-T22037
1mg49,00€5mg92,00€10mg166,00€25mg358,00€50mg530,00€100mg758,00€200mg1.044,00€1mL*10mM (DMSO)109,00€GKI-1
CAS:GKI-1, a GWL kinase inhibitor: IC50 - 4.9 µM for hGWLFL, 2.5 µM for hGWL-KinDom, 11 µM for ROCK1; weak on PKA.Fórmula:C15H12ClN3Pureza:99.96%Forma y color:SolidPeso molecular:269.73Ref: TM-T11402
1mg93,00€5mg200,00€10mg299,00€25mg485,00€50mg658,00€100mg892,00€1mL*10mM (DMSO)215,00€SJ572403
CAS:SJ572403 inhibits p27 protein, Kd 2.2 mM at D2 subdomain of p27-KID; useful in disordered protein disease research.Fórmula:C13H17N5O2Pureza:99.93%Forma y color:SolidPeso molecular:275.31Ref: TM-T16889
1mg39,00€5mg86,00€10mg119,00€25mg231,00€50mg371,00€100mg537,00€200mg710,00€1mL*10mM (DMSO)95,00€Cytembena
CAS:Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.Fórmula:C11H8BrNaO4Pureza:99.7%Forma y color:White PowderPeso molecular:307.07CDK9-IN-10
CAS:CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.Fórmula:C22H16O5Pureza:99.8%Forma y color:SolidPeso molecular:360.36DS18561882
CAS:DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.Fórmula:C28H31F3N4O6SPureza:98.19% - >99.99%Forma y color:SolidPeso molecular:608.63Ref: TM-T11103
1mg109,00€5mg260,00€10mg409,00€25mg737,00€50mg1.198,00€100mg1.611,00€1mL*10mM (DMSO)358,00€CDK8-IN-1
CAS:CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).Fórmula:C11H8F3N3OPureza:98.48%Forma y color:SolidPeso molecular:255.2Ref: TM-T10740
1mg87,00€5mg216,00€10mg311,00€25mg525,00€50mg707,00€100mg944,00€1mL*10mM (DMSO)240,00€Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.
Fórmula:C27H21N3O3Pureza:99.22%Forma y color:SolidPeso molecular:435.47Caracemide
CAS:Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Fórmula:C6H11N3O4Pureza:99.8%Forma y color:SolidPeso molecular:189.17DENV-IN-5
CAS:Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.Fórmula:C23H25ClF2N4OSPureza:99.42%Forma y color:SolidPeso molecular:478.99Ref: TM-T63143
1mg424,00€5mg964,00€10mg1.288,00€25mg1.890,00€50mg2.322,00€100mg3.060,00€1mL*10mM (DMSO)898,00€Talotrexin ammonium
CAS:Talotrexin ammonium, a non-polyglutamic antifolate, inhibits cancer by targeting DHFR.
Fórmula:C27H30N10O6Pureza:97.49%Forma y color:SolidPeso molecular:590.59Ref: TM-T64295
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€DIF-3
CAS:DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.Fórmula:C13H17ClO4Pureza:99.57%Forma y color:SolidPeso molecular:272.72Ref: TM-T60485
1mg96,00€5mg222,00€10mg333,00€25mg557,00€50mg795,00€100mg1.071,00€500mg2.187,00€1mL*10mM (DMSO)205,00€DDRI-18
CAS:DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.Fórmula:C26H20N6Pureza:98%Forma y color:SolidPeso molecular:416.48CLK-IN-T3
CAS:CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.Fórmula:C28H30N6O2Pureza:99.61%Forma y color:SolidPeso molecular:482.58Ref: TM-T14980
1mg47,00€2mg62,00€5mg92,00€10mg160,00€25mg289,00€50mg505,00€100mg787,00€200mg1.063,00€Abemaciclib metabolite M20
CAS:Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂，可用于癌症治疗的相关研究。Fórmula:C27H32F2N8OPureza:98.1% - 99.08%Forma y color:SolidPeso molecular:522.59AGX51
CAS:AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.Fórmula:C27H29NO4Pureza:97.65%Forma y color:OilPeso molecular:431.52Ref: TM-T10268
1mg96,00€5mg205,00€10mg334,00€25mg652,00€50mg858,00€100mg1.108,00€200mg1.504,00€1mL*10mM (DMSO)227,00€Ryuvidine
CAS:Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response, and can be used to study breast cancer and erythroderma.Fórmula:C15H12N2O2SPureza:98.6%Forma y color:SolidPeso molecular:284.33CD532
CAS:CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Fórmula:C26H25F3N8OPureza:99.99%Forma y color:SolidPeso molecular:522.52EHT 1610
CAS:EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.Fórmula:C18H14FN5O2SPureza:98.43%Forma y color:SolidPeso molecular:383.4Eprociclovir
CAS:Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention ofFórmula:C11H15N5O3Pureza:98.50% - 99.86%Forma y color:SolidPeso molecular:265.27DSS30
CAS:DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid secretion to help prevent Alzheimer's.Fórmula:C16H14ClNO3S2Pureza:99.19% - 99.4%Forma y color:SolidPeso molecular:367.87CMX-521
CAS:CMX521: an antiviral for norovirus, effective against rotavirus; inhibits viral RNA polymerase.Fórmula:C13H17N5O5Pureza:99.57%Forma y color:SolidPeso molecular:323.3SEL120-34A
CAS:SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.Fórmula:C15H18Br2N4Pureza:99.764% - 99.84%Forma y color:SolidPeso molecular:414.14Ref: TM-T10744
1mg612,00€5mg1.529,00€10mg1.880,00€25mg2.178,00€50mg2.862,00€100mg3.870,00€1mL*10mM (DMSO)1.835,00€UMK57
CAS:UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Fórmula:C17H17N3SPureza:99.86%Forma y color:SolidPeso molecular:295.4Firategrast
CAS:Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFórmula:C27H27F2NO6Pureza:99.67%Forma y color:SolidPeso molecular:499.5Ref: TM-TQ0291
1mg44,00€5mg93,00€10mg133,00€25mg268,00€50mg439,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)92,00€Antiviral agent 17
CAS:Antiviral agent 17, EC50 0.015 μM in human assay, effective against murine norovirus, may aid infectious/malignant disease research.Fórmula:C11H14N4O4Pureza:99.89%Forma y color:SolidPeso molecular:266.2510-Formylfolic acid
CAS:10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.Fórmula:C20H19N7O7Pureza:99.97%Forma y color:SolidPeso molecular:469.41CQ211
CAS:CQ211 is a potent selective RIOK2 inhibitor, Kd 6.1 nM, effectively inhibits cancer cell line proliferation.Fórmula:C26H22F3N7O2Pureza:97.01% - 98.31%Forma y color:SolidPeso molecular:521.49Netivudine
CAS:Netivudine, a potent NRTI with anti-varicella activity, treats HIV by inhibiting reverse transcriptase, reducing viral load.Fórmula:C12H14N2O6Pureza:99.78%Forma y color:SolidPeso molecular:282.25AS-0141
CAS:AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM)，具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶，在细胞周期中对 DNA 复制的启动至关重要。Fórmula:C21H22F3N5O4Pureza:99.97%Forma y color:SolidPeso molecular:465.43ITX3
CAS:ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.Fórmula:C22H17N3OSPureza:97.28%Forma y color:SolidPeso molecular:371.45Rho-Kinase-IN-1
CAS:Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.Fórmula:C20H24N4SPureza:99.8%Forma y color:SolidPeso molecular:352.5Ref: TM-T12721
1mg71,00€5mg138,00€10mg205,00€25mg358,00€50mg502,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)105,00€BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Fórmula:C14H16N2OSPureza:99.84%Forma y color:SolidPeso molecular:260.35Ref: TM-T36964
5mg48,00€10mg80,00€25mg160,00€50mg264,00€100mg462,00€500mg982,00€1mL*10mM (DMSO)50,00€USP30 inhibitor 11
CAS:USP30 inhibitor 11 (USP30-IN-11) is a USP30 inhibitor that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.Fórmula:C17H16N6O2SPureza:98.84% - 99.59%Forma y color:SolidPeso molecular:368.41dCeMM2
CAS:dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.Fórmula:C16H11ClN6OSPureza:99.68%Forma y color:SolidPeso molecular:370.82Ref: TM-T61477
1mg34,00€5mg74,00€10mg113,00€25mg236,00€50mg404,00€100mg600,00€500mg1.279,00€1mL*10mM (DMSO)104,00€Haspin-IN-3
CAS:Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.
Fórmula:C16H10N2O3Pureza:98.78%Forma y color:SolidPeso molecular:278.26CHK1-IN-3
CAS:CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).Fórmula:C20H23N9OPureza:98.78%Forma y color:SolidPeso molecular:405.46Ref: TM-T10791
1mg168,00€2mg231,00€5mg371,00€10mg558,00€25mg868,00€50mg1.153,00€100mg1.575,00€200mg2.125,00€1mL*10mM (DMSO)423,00€Cdk2 Inhibitor II
CAS:Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Fórmula:C14H11BrN4O3SPureza:97.27%Forma y color:SolidPeso molecular:395.23Ref: TM-T36933
1mg98,00€2mg133,00€5mg192,00€10mg289,00€25mg485,00€50mg692,00€100mg945,00€500mg1.873,00€OTUB1/USP8-IN-1
CAS:OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung cancer.Fórmula:C22H16ClFN2O4Pureza:98.59%Forma y color:SoildPeso molecular:426.83NR2F6 modulator-1
CAS:NR2F6 modulator-1, a potent agent for NR2F6, affects immune response and tumor stem cell activity.Fórmula:C23H17NO5SPureza:98.31%Forma y color:SolidPeso molecular:419.45Ref: TM-T62204
1mg87,00€5mg178,00€10mg268,00€25mg502,00€50mg703,00€100mg982,00€1mL*10mM (DMSO)203,00€SB-747651A Dihydrochloride
CAS:SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.Fórmula:C16H24Cl2N8OPureza:98.05%Forma y color:SolidPeso molecular:415.32Ref: TM-T9652
1mg70,00€5mg146,00€10mg207,00€25mg349,00€50mg497,00€100mg675,00€500mgA consultar1mL*10mM (DMSO)160,00€CHD1Li 6.11
CAS:CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.Fórmula:C21H22BrN5OSPureza:99.04%Forma y color:SolidPeso molecular:472.4Ref: TM-T63049
1mg92,00€5mg216,00€10mg354,00€25mg597,00€50mg852,00€100mg1.159,00€500mg2.327,00€1mL*10mM (DMSO)227,00€D-I03
CAS:D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.Fórmula:C23H36N6SPureza:99.65%Forma y color:SolidPeso molecular:428.64Ref: TM-T10936
1mg34,00€5mg73,00€10mg119,00€25mg236,00€50mg353,00€100mg517,00€200mg737,00€1mL*10mM (DMSO)80,00€Galocitabine
CAS:Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.Fórmula:C19H22FN3O8Pureza:99.89%Forma y color:SolidPeso molecular:439.39P22074
CAS:P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.Fórmula:C12H9NO3S2Pureza:>99.99%Forma y color:SolidPeso molecular:279.33Ref: TM-T28284
1mg137,00€5mg314,00€10mg427,00€25mg600,00€50mg798,00€100mg1.099,00€200mg1.468,00€1mL*10mM (DMSO)239,00€SJB3-019A
CAS:SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 timesFórmula:C16H8N2O3Pureza:99.72%Forma y color:SolidPeso molecular:276.25Ref: TM-T12926
1mg77,00€2mg101,00€5mg168,00€10mg253,00€25mg416,00€50mg580,00€100mg783,00€200mg1.054,00€ZIM
CAS:ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.Fórmula:C20H19N3O3Pureza:99.85%Forma y color:SolidPeso molecular:349.38CDK4/6/1 Inhibitor
CAS:CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM).Fórmula:C28H30F2N6Pureza:97.25% - 99.72%Forma y color:SolidPeso molecular:488.57TC-S 7005
CAS:TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).Fórmula:C21H17N3O3Pureza:99.516%Forma y color:SolidPeso molecular:359.38Ref: TM-T17008
1mg57,00€2mg84,00€5mg125,00€10mg188,00€25mg354,00€50mg532,00€100mg712,00€500mgA consultar1mL*10mM (DMSO)138,00€ERCC1-XPF-IN-2
CAS:ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).
Fórmula:C15H13Cl2NO3Pureza:98.21%Forma y color:SolidPeso molecular:326.17Ref: TM-T60904
2mg40,00€5mg60,00€10mg96,00€25mg187,00€50mg311,00€100mg472,00€200mg658,00€500mg1.026,00€GRK6-IN-1
CAS:GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Fórmula:C22H23ClN6O2Pureza:99.37%Forma y color:SolidPeso molecular:438.91Ref: TM-T62518
1mg54,00€5mg114,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€1mL*10mM (DMSO)126,00€116-9e
CAS:116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.Fórmula:C31H32N2O5Pureza:99.55%Forma y color:SolidPeso molecular:512.6Ref: TM-T25770
1mg50,00€5mg105,00€10mg170,00€25mg355,00€50mg595,00€100mg862,00€200mg1.153,00€1mL*10mM (DMSO)34,00€HA-1004
CAS:HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.Fórmula:C12H15N5O2SPureza:99.56% - 99.63%Forma y color:SolidPeso molecular:293.34CRT-0105950
CAS:CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Fórmula:C21H16ClN3OSPureza:99.78% - 99.86%Forma y color:SolidPeso molecular:393.89Ref: TM-T23917
1mg65,00€5mg140,00€10mg216,00€25mg439,00€50mg707,00€100mg1.130,00€1mL*10mM (DMSO)156,00€BioE-1115
CAS:BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).Fórmula:C19H18FN3O2Pureza:97.54%Forma y color:SolidPeso molecular:339.36ProINDY
CAS:ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome.Fórmula:C14H15NO3SPureza:97.19%Forma y color:SolidPeso molecular:277.34Cdc7-IN-7c
CAS:Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.Fórmula:C15H17N5OSPureza:98.19% - 99.22%Forma y color:SolidPeso molecular:315.39Ref: TM-T23867
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€1mL*10mM (DMSO)600,00€Rhodblock 6
CAS:Rhodblock 6 is a Rho kinase inhibitor, blocking phosphorylated MRLC localization by targeting ROCK activity.Fórmula:C12H13N3OPureza:99.87%Forma y color:SolidPeso molecular:215.25ML 315
CAS:ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.Fórmula:C18H13Cl2N3O2Pureza:99.08%Forma y color:SolidPeso molecular:374.22(S)-PF-06873600
CAS:(S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.Fórmula:C20H27F2N5O4SPureza:98.59%Forma y color:SolidPeso molecular:471.52Elarofiban
CAS:Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Fórmula:C22H32N4O4Pureza:98.76%Forma y color:SolidPeso molecular:416.51Talviraline
CAS:Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in aFórmula:C15H20N2O3S2Pureza:99.88%Forma y color:SolidPeso molecular:340.46CDK-IN-2
CAS:CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: <8 nM).Fórmula:C18H19ClFN3O2Pureza:99.67%Forma y color:SolidPeso molecular:363.81Ref: TM-TQ0078
1mg38,00€2mg51,00€5mg96,00€10mg138,00€25mg258,00€50mg376,00€100mg532,00€500mg1.063,00€1mL*10mM (DMSO)92,00€Peldesine
CAS:Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Fórmula:C12H11N5OPureza:99.27% - 99.9%Forma y color:SolidPeso molecular:241.25Ref: TM-T12399
1mg108,00€5mg260,00€10mg416,00€25mg690,00€50mg964,00€100mg1.305,00€500mg2.592,00€1mL*10mM (DMSO)286,00€Lotrafiban hydrochloride
CAS:Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.Fórmula:C23H33ClN4O4Forma y color:SolidPeso molecular:464.99KIF18A-IN-7
CAS:KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependentFórmula:C27H35N3O5S2Forma y color:SoildPeso molecular:545.71NTRC 0066-0
CAS:NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.Fórmula:C33H39N7O2Pureza:98.30%Forma y color:SolidPeso molecular:565.71N-desmethyl Netupitant
CAS:N-desmethyl Netupitant is a metabolite of Netupitant and a potential Substance-P receptor agonist.Fórmula:C29H30F6N4OPureza:98%Forma y color:SolidPeso molecular:564.57Palbociclib orotate
CAS:Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively.Fórmula:C29H33N9O6Pureza:98%Forma y color:SolidPeso molecular:603.63Butylparaben sodium
CAS:Butylparaben sodium significantly impacts the later phases of spermatogenesis in the testes by impairing hormonal regulation and/or RNA and protein synthesis [1Fórmula:C11H13NaO3Pureza:98%Forma y color:SolidPeso molecular:216.21CDK4-IN-2
CAS:CDK4-IN-2 (A17) is a potent inhibitor of CDK4, exhibiting K i and IC 50 values of less than 10 nM and is utilized in cancer research [1].Fórmula:C22H26F2N6O4SPureza:98%Forma y color:SolidPeso molecular:508.54Homouridine
CAS:Homouridine, an analogue of uridine, functions as an intermediate in the synthesis of MMP-2 inhibitor (compound I, IC50 = 150 μM).Fórmula:C10H14N2O6Pureza:98%Forma y color:SolidPeso molecular:258.23CDK9-IN-9
CAS:CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).Fórmula:C22H23F2N5O2SPureza:98%Forma y color:SolidPeso molecular:459.51Cytidine 3'-monophosphate
CAS:Cytidine 3'-monophosphate, a ribonucleotide, results from the hydrolysis of cytidine 2',3'-cyclic monophosphate via RNase—a process that cytidine 3'-monophosphate itself inhibits. Additionally, it can be dephosphorylated to cytidine by 3'-nucleotidase.Fórmula:C9H14N3O8PForma y color:SolidPeso molecular:323.2CCT239065
CAS:CCT239065 is a novel, selective, and efficacious nanomolar pyridopyrazinone V600EBRAF and LCK inhibitor.Fórmula:C29H29N7O3SForma y color:SolidPeso molecular:555.65Pelitrexol
CAS:Pelitrexol (AG2037) is a GARFT inhibitor, which can inhibit the activity of mTORC1, block the cell cycle in the s-phase, with antiproliferative activity,NSCLC .Fórmula:C20H25N5O6SPureza:98.03%Forma y color:SolidPeso molecular:463.51Mps1-IN-10
CAS:Mps1-IN-6 (Compound 9) is a highly effective Mps1 inhibitor with an IC50 value of 6.4 nM and exhibits significant anti-proliferation and anti-tumor effects onFórmula:C24H27N7O2Forma y color:SolidPeso molecular:445.52CDK9-IN-19
CAS:CDK9-IN-19: Potent CDK9 inhibitor, anti-cancer, moderate pharmacokinetics, low hERG impact, effective in AML research.Fórmula:C26H22F2N4O5Forma y color:SolidPeso molecular:508.47CCT-271850
CAS:CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.Fórmula:C24H29N7OPureza:98%Forma y color:SolidPeso molecular:431.53KSP-IA
CAS:KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.Fórmula:C21H22F2N2OPureza:98%Forma y color:SolidPeso molecular:356.41
