Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(544 productos)
- Detención del ciclo celular(5 productos)
- Chk(47 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(230 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(273 productos)
- PKC(119 productos)
- PLK(25 productos)
- ROCK(63 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3831 productos de "Ciclo celular / Checkpoint"
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Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Fórmula:C21H27N7OPureza:98% - 99.45%Forma y color:SolidPeso molecular:393.49Ref: TM-T1825
1mg35,00€2mg50,00€5mg66,00€10mg84,00€25mg156,00€50mg212,00€100mg371,00€1mL*10mM (DMSO)66,00€Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Forma y color:SolidPeso molecular:375.37S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Fórmula:C22H21NO2SPureza:97.02%Forma y color:Almost White To Light Yellow Granular PowderPeso molecular:363.47Brr2-IN-3
CAS:Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.Fórmula:C24H20N4O3SPureza:99.26%Forma y color:SolidPeso molecular:444.51Ref: TM-T22282
1mg52,00€2mg65,00€5mg92,00€10mg161,00€25mg290,00€50mg420,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)110,00€Hesperadin
CAS:Hesperadin(IC50=250 nM) effectively inhibits Aurora B.Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Forma y color:SolidPeso molecular:516.65MLS000532223
CAS:MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).Fórmula:C15H9NO3Pureza:98.6%Forma y color:SolidPeso molecular:251.24Ref: TM-T8473
1mg105,00€5mg250,00€10mg401,00€25mg685,00€50mg982,00€100mg1.341,00€1mL*10mM (DMSO)301,00€GSK-25
CAS:GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K, and a dramatically improved P450 profile.Fórmula:C24H16Cl2F2N6OPureza:98.59%Forma y color:SolidPeso molecular:513.33Ref: TM-T4488
1mg44,00€2mg56,00€5mg87,00€10mg111,00€25mg168,00€50mg258,00€100mg430,00€1mL*10mM (DMSO)89,00€A-674563 2HCl(552325-73-2(fb-2hcl))
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.Fórmula:C22H24Cl2N4OPureza:94.66%Forma y color:SolidPeso molecular:431.36Ref: TM-T6139L
1mg86,00€5mg138,00€10mg188,00€25mg335,00€50mg505,00€100mg730,00€1mL*10mM (DMSO)170,00€Dasabuvir sodium
CAS:Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).Fórmula:C26H26N3NaO5SForma y color:SolidPeso molecular:515.56Palbociclib
CAS:Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.Fórmula:C24H29N7O2Pureza:98% - 99.9%Forma y color:SolidPeso molecular:447.53K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Fórmula:C13H15N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:277.34Favipiravir sodium
CAS:Favipiravir sodium inhibits viral RNA polymerases, effective against flu, West Nile, yellow fever, and more RNA viruses.Fórmula:C5H4FN3NaO2Forma y color:SolidPeso molecular:180.09IMP-1088
CAS:IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Fórmula:C25H29F2N5OPureza:98.48% - 99.52%Forma y color:SolidPeso molecular:453.53Ref: TM-T9350
1mg144,00€2mg188,00€5mg283,00€10mg469,00€25mg833,00€50mg1.121,00€1mL*10mM (DMSO)310,00€BTYNB
CAS:BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Fórmula:C12H9BrN2OSPureza:≥95%Forma y color:SolidPeso molecular:309.186-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Fórmula:C10H13N5O3SPureza:97.52%Forma y color:SolidPeso molecular:283.31CHR-6494
CAS:CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).Fórmula:C16H16N6Pureza:98.78%Forma y color:SolidPeso molecular:292.34Ref: TM-T14959
5mg54,00€10mg82,00€25mg145,00€50mg259,00€100mg442,00€200mg643,00€1mL*10mM (DMSO)60,00€TAK-960 hydrochloride
CAS:TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.Fórmula:C27H35ClF3N7O3Forma y color:SolidPeso molecular:598.06CCT 137690
CAS:CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Forma y color:SolidPeso molecular:551.48SL327
CAS:SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.Fórmula:C16H12F3N3SPureza:97.98% - >99.99%Forma y color:SolidPeso molecular:335.35Apcin
CAS:Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.Fórmula:C13H14Cl3N7O4Pureza:96.74%Forma y color:SolidPeso molecular:438.65Ref: TM-T8561
1mg48,00€2mg63,00€5mg87,00€10mg140,00€25mg274,00€50mg472,00€100mg710,00€1mL*10mM (DMSO)97,00€
