Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(544 productos)
- Detención del ciclo celular(5 productos)
- Chk(47 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(230 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(273 productos)
- PKC(120 productos)
- PLK(25 productos)
- ROCK(63 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
Mostrar 10 subcategorías más
Se han encontrado 3832 productos de "Ciclo celular / Checkpoint"
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Atuveciclib
CAS:Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.Fórmula:C18H18FN5O2SPureza:98.8%Forma y color:SolidPeso molecular:387.43Ref: TM-T10464L
1mg88,00€2mg120,00€5mg202,00€10mg329,00€25mg612,00€50mg817,00€100mg1.121,00€1mL*10mM (DMSO)224,00€Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Fórmula:C27H40N8O7Pureza:98% - 99.8%Forma y color:SolidPeso molecular:588.66Danusertib
CAS:Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Fórmula:C26H30N6O3Pureza:97.88% - 98.79%Forma y color:White PowderPeso molecular:474.55KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Fórmula:C20H20N4OPureza:98.43% - 99.69%Forma y color:SolidPeso molecular:332.4Silver sulfadiazine
CAS:Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.Fórmula:C10H9AgN4O2SPureza:99.04% - 99.58%Forma y color:SolidPeso molecular:357.14Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Fórmula:C12H22N6O6Pureza:99.11%Forma y color:SolidPeso molecular:346.34YKL-5-124
CAS:YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displaysFórmula:C28H33N7O3Pureza:99.36%Forma y color:SolidPeso molecular:515.61Ref: TM-T22461
1mg96,00€2mg135,00€5mg188,00€10mg341,00€25mg548,00€50mg782,00€100mg1.035,00€1mL*10mM (DMSO)225,00€PTC-209 hydrobromide
CAS:PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in
Fórmula:C17H13Br2N5OS·HBrPureza:99.91%Forma y color:SolidPeso molecular:576.1Ref: TM-T6178
1mg37,00€5mg78,00€10mg124,00€25mg265,00€50mg465,00€100mg753,00€200mg1.035,00€1mL*10mM (DMSO)89,00€Bredinin aglycone
CAS:Bredinin aglycone (SM-108) is a purine nucleotide analog.Fórmula:C4H5N3O2Pureza:99.06%Forma y color:SolidPeso molecular:127.1WEE1-IN-3
CAS:WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.Fórmula:C28H31N7O2Pureza:98.33%Forma y color:SolidPeso molecular:497.59Ref: TM-T8916
1mg70,00€5mg156,00€10mg239,00€25mg419,00€50mg562,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)170,00€HALOFUGINONE LACTATE
CAS:HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.Fórmula:C19H23BrClN3O6Pureza:99.70% - 99.96%Forma y color:SolidPeso molecular:504.8Ref: TM-T8785
2mg39,00€5mg56,00€10mg89,00€25mg123,00€50mg197,00€100mg294,00€200mg437,00€1mL*10mM (DMSO)63,00€dGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFórmula:C10H16N5O13P3Pureza:99.64%Forma y color:SolidPeso molecular:507.182'-Fluoro-2'-Deoxyadenosine
CAS:2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Fórmula:C10H12FN5O3Pureza:99.95%Forma y color:SolidPeso molecular:269.23Carotegrast methyl
CAS:Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Fórmula:C28H26Cl2N4O5Pureza:99.26% - 99.72%Forma y color:SolidPeso molecular:569.44Levomefolate calcium
CAS:Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.Fórmula:C20H23CaN7O6Pureza:97.35%Forma y color:Off-White To Pale Yellow SolidPeso molecular:497.52AZD-7762
CAS:AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.Fórmula:C17H19FN4O2SPureza:98.96% - 99.19%Forma y color:SolidPeso molecular:362.42Ref: TM-T6093
1mg35,00€2mg50,00€5mg77,00€10mg90,00€25mg167,00€50mg265,00€100mg424,00€1mL*10mM (DMSO)84,00€CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Fórmula:C21H17ClF6N2O2Pureza:99.58%Forma y color:SolidPeso molecular:478.82Ref: TM-T22062
5mg35,00€10mg54,00€25mg108,00€50mg178,00€100mg286,00€200mg425,00€1mL*10mM (DMSO)40,00€Abemaciclib
CAS:Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.Fórmula:C27H32F2N8Pureza:99.43% - 99.87%Forma y color:SolidPeso molecular:506.59NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFórmula:C38H43N3O6Pureza:99.16% - 99.27%Forma y color:SolidPeso molecular:637.76NSC23005 Sodium
CAS:NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Fórmula:C13H16NNaO4SPureza:99.64%Forma y color:SolidPeso molecular:305.32
