Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(545 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(248 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(273 productos)
- PKC(124 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3857 productos de "Ciclo celular / Checkpoint"
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Isoindigotin
CAS:Isoindigotin is used in the therapy of Y.
Fórmula:C16H10N2O2Pureza:98.14% - ≥95%Forma y color:SolidPeso molecular:262.26Pyridostatin Trihydrochloride
CAS:Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.Fórmula:C31H35Cl3N8O5Pureza:99.69%Forma y color:SolidPeso molecular:706.026-Thioinosine
CAS:6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.Fórmula:C10H12N4O4SPureza:97.74%Forma y color:SolidPeso molecular:284.29CCG-203971
CAS:CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Fórmula:C23H21ClN2O3Pureza:98.82% - 99.50%Forma y color:SolidPeso molecular:408.88RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Fórmula:C14H11Cl3N2O3Pureza:99.3% - 99.62%Forma y color:SolidPeso molecular:361.61TMPyP4 tosylate
CAS:TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.Fórmula:C72H66N8O12S4Pureza:98.61% - 99.85%Forma y color:SolidPeso molecular:1363.6Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFórmula:C31H32N8O5Pureza:98%Forma y color:SolidPeso molecular:596.64Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Fórmula:C27H32N8O2Pureza:98.65% - 99.86%Forma y color:SolidPeso molecular:500.6Ref: TM-T2077
5mg46,00€10mg66,00€25mg81,00€50mg96,00€100mg110,00€200mg161,00€500mg260,00€1mL*10mM (DMSO)49,00€CK7
CAS:CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Fórmula:C14H12N6O2SPureza:99.54%Forma y color:SolidPeso molecular:328.35Ref: TM-T9615
1mg52,00€5mg120,00€10mg187,00€25mg376,00€50mg588,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)133,00€Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Fórmula:C14H12ClN3O4S2Pureza:98.68% - 99.77%Forma y color:SolidPeso molecular:385.85Ref: TM-T4321
1mg34,00€2mg43,00€5mg63,00€10mg88,00€25mg130,00€50mg198,00€100mg298,00€1mL*10mM (DMSO)69,00€Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Fórmula:C22H23N7OPureza:98.68% - 99.64%Forma y color:SolidPeso molecular:401.46Ro3280
CAS:Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Fórmula:C27H35F2N7O3Pureza:97.1% - >99.99%Forma y color:SolidPeso molecular:543.61HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Fórmula:C17H13NO2Pureza:99.96%Forma y color:SolidPeso molecular:263.29IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Fórmula:C24H21ClFNO6Pureza:98.26% - 99.83%Forma y color:SolidPeso molecular:473.88Ref: TM-T8842
1mg138,00€5mg295,00€10mg505,00€25mg733,00€50mg888,00€100mg1.251,00€1mL*10mM (DMSO)309,00€AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Fórmula:C16H14Cl2N8OPureza:>99.99%Forma y color:SolidPeso molecular:405.24Ref: TM-T8378
1mg124,00€2mg170,00€5mg260,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€1mL*10mM (DMSO)286,00€BRD9876
CAS:BRD9876 is a selective inhibitor of MM1S growth.Fórmula:C16H14N2Pureza:97.81%Forma y color:SolidPeso molecular:234.3RK33
CAS:"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Fórmula:C23H20N6O3Pureza:99.04% - 99.72%Forma y color:SolidPeso molecular:428.44T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFórmula:C29H27NO8Pureza:97.88% - 99.29%Forma y color:SolidPeso molecular:517.53Ref: TM-T5416
1mg48,00€5mg96,00€10mg144,00€25mg254,00€50mg424,00€100mg627,00€200mg998,00€1mL*10mM (DMSO)107,00€Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Forma y color:SolidPeso molecular:938.71BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Fórmula:C16H17N5Pureza:90%Forma y color:SolidPeso molecular:279.34
