Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(249 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(124 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
Mostrar 10 subcategorías más
Se han encontrado 3864 productos de "Ciclo celular / Checkpoint"
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Fanotaprim
CAS:Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.Fórmula:C19H22N8OPureza:98.1%Forma y color:SolidPeso molecular:378.43Ref: TM-T36692
1mg52,00€2mg74,00€5mg116,00€10mg178,00€25mg335,00€50mg467,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)128,00€HA-100
CAS:HA-100 is an inhibitor of protein kinaseFórmula:C13H15N3O2SPureza:99.44%Forma y color:Pale Yellow Crystalline SolidPeso molecular:277.34PNU112455A hydrochloride
CAS:PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.Fórmula:C10H12ClN5O2SPureza:98.58% - 99.22%Forma y color:SolidPeso molecular:301.75Ref: TM-T8230
2mg44,00€5mg71,00€10mg100,00€25mg172,00€50mg266,00€100mg434,00€500mg964,00€1mL*10mM (DMSO)79,00€Ribociclib succinate hydrate
CAS:Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).Fórmula:C27H38N8O6Pureza:98%Forma y color:SolidPeso molecular:570.651CAN508
CAS:CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.Fórmula:C9H10N6OPureza:98.65%Forma y color:SolidPeso molecular:218.22TAK-632
CAS:TAK-632 is a potent pan-Raf inhibitor.Fórmula:C27H18F4N4O3SPureza:98% - 99.5%Forma y color:SolidPeso molecular:554.52Palmatine
CAS:Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Fórmula:C21H22NO4Pureza:96.28% - 99.49%Forma y color:SolidPeso molecular:352.4SPHINX
CAS:SPHINX is a new generation inhibitor of SPRK1Fórmula:C17H17F3N2O3Pureza:99.29%Forma y color:SolidPeso molecular:354.32Hu7691
CAS:Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.Fórmula:C22H22ClF3N4OPureza:99.81%Forma y color:SolidPeso molecular:450.887BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Fórmula:C16H10BrN3O2Pureza:99.67%Forma y color:SolidPeso molecular:356.17SBC-115337
CAS:SBC-115337 is a PCSK9 inhibitor.Fórmula:C29H19N3O4Pureza:99.41%Forma y color:SolidPeso molecular:473.48Simeprevir
CAS:Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Fórmula:C38H47N5O7S2Pureza:99.45% - 99.92%Forma y color:SolidPeso molecular:749.94WR99210 hydrochloride(47326-86-3 free base)
CAS:WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.Fórmula:C14H19Cl4N5O2Pureza:97.77% - 99.8%Forma y color:SolidPeso molecular:431.14Ref: TM-T17257L
1mg62,00€5mg132,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€200mg954,00€1mL*10mM (DMSO)157,00€WNK-IN-11
CAS:WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)Fórmula:C21H21Cl2N5OSPureza:98.32%Forma y color:SolidPeso molecular:462.4Ref: TM-T5456
1mg87,00€5mg172,00€10mg280,00€25mg474,00€50mg683,00€100mg964,00€500mg1.918,00€1mL*10mM (DMSO)188,00€3'-Deoxyguanosine
CAS:3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.Fórmula:C10H13N5O4Pureza:98.85% - 98.96%Forma y color:SolidPeso molecular:267.24Phosphonoformic acid trisodium salt hexa
CAS:Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.Fórmula:CH12Na3O11PPureza:98%Forma y color:SolidPeso molecular:300.03Cyclo(RGDyK) trifluoroacetate
CAS:Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Fórmula:C31H43F6N9O12Pureza:95.28% - ≥95%Forma y color:SolidPeso molecular:847.72PfDHODH-IN-1
CAS:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Fórmula:C14H11F3N2O2Pureza:99.87%Forma y color:SolidPeso molecular:296.24Ref: TM-T12438
1mg52,00€5mg101,00€10mg152,00€25mg295,00€50mg447,00€100mg658,00€200mg888,00€1mL*10mM (DMSO)92,00€GAK inhibitor 49 hydrochloride
Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.Fórmula:C20H23ClN2O5Forma y color:SolidPeso molecular:406.86Tirapazamine
CAS:Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.Fórmula:C7H6N4O2Pureza:96.65% - 99.87%Forma y color:Orange-Red Crystalline PowderPeso molecular:178.15
